Works by Scott G. Franzblau

Results: 45

Synthesis, antimycobacterial, cytotoxicity, anti‐inflammatory, in silico studies and molecular dynamics of pyrazole‐embedded thiazolidin‐4‐one hybrids.

Published in:

Archiv der Pharmazie, 2023, v. 356, n. 3, p. 1, doi. 10.1002/ardp.202200444

By:

Kamat, Vinuta;
Poojary, Boja;
Puthran, Divyaraj;
Das, Vishwa B.;
Kumar, Banoth K.;
Sankaranarayan, Murugesan;
Shetye, Gauri;
Ma, Rui;
Franzblau, Scott G.;
Nayak, Suresh P.

Publication type:

Article

Anti-Microbial Activity of Aliphatic Alcohols from Chinese Black Cardamom (Amomum tsao - ko) against Mycobacterium tuberculosis H37Rv.

Published in:

Plants (2223-7747), 2023, v. 12, n. 1, p. 34, doi. 10.3390/plants12010034

By:

Lee, So Young;
Shetye, Gauri S.;
Son, So-Ri;
Lee, Hyun;
Klein, Larry L.;
Yoshihara, Jeffrey K.;
Ma, Rui;
Franzblau, Scott G.;
Cho, Sanghyun;
Jang, Dae Sik

Publication type:

Article

Chemical Diversity and Antimicrobial Potential of Cultivable Fungi from Deep-Sea Sediments of the Gulf of Mexico.

Published in:

Molecules, 2021, v. 26, n. 23, p. 7328, doi. 10.3390/molecules26237328

By:

Villanueva-Silva, Rodrigo;
Velez, Patricia;
Riquelme, Meritxell;
Fajardo-Hernández, Carlos A.;
Martínez-Cárdenas, Anahí;
Arista-Romero, Alejandra;
Wan, Baojie;
Ma, Rui;
Qader, Mallique;
Franzblau, Scott G.;
Figueroa, Mario

Publication type:

Article

Synthesis and Activity against Mycobacterium tuberculosis of Olivacine and Oxygenated Derivatives.

Published in:

Molecules, 2018, v. 23, n. 6, p. 1402, doi. 10.3390/molecules23061402

By:

Schmidt, Ulrike;
Theumer, Gabriele;
Jäger, Anne;
Kataeva, Olga;
Wan, Baojie;
Franzblau, Scott G.;
Knölker, Hans-Joachim

Publication type:

Article

Antitubercular and Cytotoxic Constituents from Goniothalamus gitingensis.

Published in:

Records of Natural Products, 2014, v. 8, n. 1, p. 41

By:

Macabeo, Allan Patrick G.;
Lopez, Amier Dayle A.;
Schmidt, Sebastian;
Heilmann, Jörg;
Dahse, Hans-Martin;
Alejandro, Grecebio Jonathan D.;
Franzblau, Scott G.

Publication type:

Article

Phytoconstituents from Alpinia purpurata and their in vitro inhibitory activity against Mycobacterium tuberculosis.

Published in:

Pharmacognosy Magazine, 2010, v. 6, n. 24, p. 339, doi. 10.4103/0973-1296.71785

By:

Villaflores, Oliver B.;
Macabeo, Allan Patrick G.;
Gehle, Dietmar;
Krohn, Karsten;
Franzblau, Scott G.;
Aguinaldo, Alicia M.

Publication type:

Article

Antitubercular and cytotoxic polyoxygenated cyclohexane derivatives from Uvaria grandiflora.

Published in:

Natural Product Research, 2021, v. 35, n. 23, p. 5229, doi. 10.1080/14786419.2020.1741579

By:

Macabeo, Allan Patrick G.;
Flores, Angeli Izza G.;
Fernandez, Rey Arturo T.;
Budde, Simon;
Faderl, Christian;
Dahse, Hans-Martin;
Franzblau, Scott G.

Publication type:

Article

An iboga alkaloid chemotaxonomic marker from endemic Tabernaemontana ternifolia with antitubercular activity.

Published in:

Natural Product Research, 2020, v. 34, n. 8, p. 1175, doi. 10.1080/14786419.2018.1550759

By:

Garcellano, Rhea C.;
Cort, John R.;
Moinuddin, Syed G. A.;
Franzblau, Scott G.;
Ma, Rui;
Aguinaldo, Alicia M.

Publication type:

Article

Dereplication of pentacyclic triterpenoids in plants by GC-EI/MS.

Published in:

Phytochemical Analysis, 2006, v. 17, n. 2, p. 102, doi. 10.1002/pca.892

By:

Gu, Jian-Qiao;
Wang, Yuehong;
Franzblau, Scott G.;
Montenegro, Gloria;
Timmermann, Barbara N.

Publication type:

Article

Antitubercular activity of the semi–polar extractives of Uvaria rufa

Published in:

Asian Pacific Journal of Tropical Medicine, 2012, v. 5, n. 10, p. 777, doi. 10.1016/S1995-7645(12)60142-4

By:

Macabeo, Allan Patrick G;
Tudla, Florie A;
Krohn, Karsten;
Franzblau, Scott G

Publication type:

Article

Biophysical Screening of a Focused Library for the Discovery of CYP121 Inhibitors as Novel Antimycobacterials.

Published in:

ChemMedChem, 2017, v. 12, n. 19, p. 1616, doi. 10.1002/cmdc.201700363

By:

Brengel, Christian;
Thomann, Andreas;
Schifrin, Alexander;
Allegretta, Giuseppe;
Kamal, Ahmed A. M.;
Haupenthal, Jörg;
Schnorr, Isabell;
Cho, Sang Hyun;
Franzblau, Scott G.;
Empting, Martin;
Eberhard, Jens;
Hartmann, Rolf W.

Publication type:

Article

Small Molecules Targeting Mycobacterium tuberculosis Type II NADH Dehydrogenase Exhibit Antimycobacterial Activity.

Published in:

Angewandte Chemie International Edition, 2018, v. 57, n. 13, p. 3478, doi. 10.1002/anie.201800260

By:

Harbut, Michael B.;
Yang, Baiyuan;
Liu, Renhe;
Yano, Takahiro;
Vilchèze, Catherine;
Cheng, Bo;
Lockner, Jonathan;
Guo, Hui;
Yu, Chenguang;
Franzblau, Scott G.;
Petrassi, H. Mike;
Jacobs, Jr., William R.;
Rubin, Harvey;
Chatterjee, Arnab K.;
Wang, Feng

Publication type:

Article

Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes.

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 42, p. 13011, doi. 10.1002/anie.201707324

By:

Liu, Renhe;
Lyu, Xiaoxuan;
Batt, Sarah M;
Hsu, Mei-Hui;
Harbut, Michael B;
Vilchèze, Catherine;
Cheng, Bo;
Ajayi, Kehinde;
Yang, Baiyuan;
Yang, Yun;
Guo, Hui;
Lin, Changyou;
Gan, Fei;
Wang, Chen;
Franzblau, Scott G.;
Jacobs, William R.;
Besra, Gurdyal S.;
Johnson, Eric F.;
Petrassi, Mike;
Chatterjee, Arnab K.

Publication type:

Article

Bioassay-Guided Isolation and Structural Modification of the Anti- TB Resorcinols from Ardisia gigantifolia.

Published in:

Chemical Biology & Drug Design, 2016, v. 88, n. 2, p. 293, doi. 10.1111/cbdd.12756

By:

Guan, Yi ‐ Fu;
Song, Xun;
Qiu, Ming ‐ Hua;
Luo, Shi ‐ Hong;
Wang, Bao ‐ Jie;
Van Hung, Nguyen;
Cuong, Nguyen M.;
Soejarto, Djaja Doel;
Fong, Harry H.S.;
Franzblau, Scott G.;
Li, Sheng ‐ Hong;
He, Zhen ‐ Dan;
Zhang, Hong ‐ Jie

Publication type:

Article

6-Hydrogen-8-Methylquinolones Active Against Replicating and Non-replicating Mycobacterium tuberculosis.

Published in:

Chemical Biology & Drug Design, 2012, v. 80, n. 5, p. 781, doi. 10.1111/cbdd.12022

By:

Tabarrini, Oriana;
Sabatini, Stefano;
Massari, Serena;
Pieroni, Marco;
Franzblau, Scott G.;
Cecchetti, Violetta

Publication type:

Article

Quinoline‐Proline, Triazole Hybrids: Design, Synthesis, Antituberculosis, Molecular Docking, and ADMET Studies.

Published in:

Journal of Heterocyclic Chemistry, 2021, v. 58, n. 4, p. 952, doi. 10.1002/jhet.4229

By:

Ganesan, Moorthiamma Sarathy;
Raja, Kamatchi Kanmani;
Murugesan, Sankaranarayanan;
Karankumar, Banoth;
Faheem, Faheem;
Thirunavukkarasu, Sappanimuthu;
Shetye, Gauri;
Ma, Rui;
Franzblau, Scott G.;
Wan, Baojie;
Rajagopal, Gurusamy

Publication type:

Article

Activity of Scottish Plant, Lichen and Fungal Endophyte Extracts against Mycobacterium aurum and Mycobacterium tuberculosis.

Published in:

Phytotherapy Research, 2010, v. 24, n. 5, p. 692, doi. 10.1002/ptr.2988

By:

Gordien, Andréa Y.;
Gray, Alexander I.;
Ingleby, Kevin;
Franzblau, Scott G.;
Seidel, Véronique

Publication type:

Article

Antitubercular sterols from Thalia multiflora Horkel ex Koernicke.

Published in:

Phytotherapy Research, 2005, v. 19, n. 10, p. 876, doi. 10.1002/ptr.1731

By:

Gutierrez-Lugo, Maria-Teresa;
Wang, Yuehong;
Franzblau, Scott G.;
Suarez, Enrique;
Timmermann, Barbara N.

Publication type:

Article

Antitubercular constituents from the hexane fraction of Morinda citrifolia Linn. (Rubiaceae).

Published in:

Phytotherapy Research, 2002, v. 16, n. 7, p. 683, doi. 10.1002/ptr.1003

By:

Saludes, Jonel P.;
Garson, Mary J.;
Franzblau, Scott G.;
Aguinaldo, Alicia M.

Publication type:

Article

Biological Profiling Enables Rapid Mechanistic Classification of Phenotypic Screening Hits and Identification of KatG Activation-Dependent Pyridine Carboxamide Prodrugs With Activity Against Mycobacterium tuberculosis.

Published in:

Frontiers in Cellular & Infection Microbiology, 2020, v. 10, p. N.PAG, doi. 10.3389/fcimb.2020.582416

By:

Chengalroyen, Melissa D.;
Jordaan, Audrey;
Seldon, Ronnett;
Ioerger, Thomas;
Franzblau, Scott G.;
Nasr, Mohamed;
Warner, Digby F.;
Mizrahi, Valerie

Publication type:

Article

Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.

Published in:

ChemMedChem, 2011, v. 6, n. 6, p. 1041, doi. 10.1002/cmdc.201100003

By:

Lu, Jing-Ping;
Yuan, Xiu-Hua;
Yuan, Hai;
Wang, Wen-Long;
Wan, Baojie;
Franzblau, Scott G.;
Ye, Qi-Zhuang

Publication type:

Article

Design, Synthesis, and Pharmacological Evaluation of Mefloquine-Based Ligands as Novel Antituberculosis Agents.

Published in:

ChemMedChem, 2007, v. 2, n. 11, p. 1624, doi. 10.1002/cmdc.200700112

By:

Mao, Jialin;
Wang, Yuehong;
Wan, Baojie;
Kozikowski, Alan P.;
Franzblau, Scott G.

Publication type:

Article

HTS, Chemical Hybridization, and Drug Design Identify a Chemically Unique Antituberculosis Agent-Coupling Serendipity and Rational Approaches to Drug Discovery.

Published in:

ChemMedChem, 2007, v. 2, n. 6, p. 811, doi. 10.1002/cmdc.200700048

By:

Mao, Jialin;
Wan, Baojie;
Wang, Yuehong;
Franzblau, Scott G.;
Kozikowski, Alan P.

Publication type:

Article

Synthesis and Activity of Carbazole Derivatives Against Mycobacterium tuberculosis.

Published in:

ChemMedChem, 2006, v. 1, n. 8, p. 812, doi. 10.1002/cmdc.200600002

By:

Choi, Taylor A.;
Czerwonka, Regina;
Fröhner, Wolfgang;
Krahl, Micha P.;
Reddy, Kethiri R.;
Franzblau, Scott G.;
Knölker, Hans-Joachim

Publication type:

Article

Design, Synthesis, and SAR Studies of Mefloquine-Based Ligands as Potential Antituberculosis Agents.

Published in:

ChemMedChem, 2006, v. 1, n. 7, p. 667, doi. 10.1002/cmdc.200690024

By:

Jayaprakash, Sarva;
Iso, Yasuyoshi;
Wan, Baojie;
Franzblau, Scott G.;
Kozikowski, Alan P.

Publication type:

Article

Design, Synthesis, and SAR Studies of Mefloquine-Based Ligands as Potential Antituberculosis Agents.

Published in:

ChemMedChem, 2006, v. 1, n. 6, p. 593, doi. 10.1002/cmdc.200600010

By:

Jayaprakash, Sarva;
Iso, Yasuyoshi;
Wan, Baojie;
Franzblau, Scott G.;
Kozikowski, Alan P.

Publication type:

Article

Cover Picture: Design, Synthesis, and SAR Studies of Mefloquine-Based Ligands as Potential Antituberculosis Agents (ChemMedChem 6/2006).

Published in:

ChemMedChem, 2006, v. 1, n. 6, p. 577, doi. 10.1002/cmdc.200690018

By:

Jayaprakash, Sarva;
Iso, Yasuyoshi;
Wan, Baojie;
Franzblau, Scott G.;
Kozikowski, Alan P.

Publication type:

Article

Small Molecules Targeting Mycobacterium tuberculosis Type II NADH Dehydrogenase Exhibit Antimycobacterial Activity.

Published in:

Angewandte Chemie, 2018, v. 130, n. 13, p. 3536, doi. 10.1002/ange.201800260

By:

Harbut, Michael B.;
Yang, Baiyuan;
Liu, Renhe;
Yano, Takahiro;
Vilchèze, Catherine;
Cheng, Bo;
Lockner, Jonathan;
Guo, Hui;
Yu, Chenguang;
Franzblau, Scott G.;
Petrassi, H. Mike;
Jacobs, Jr., William R.;
Rubin, Harvey;
Chatterjee, Arnab K.;
Wang, Feng

Publication type:

Article

Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes.

Published in:

Angewandte Chemie, 2017, v. 129, n. 42, p. 13191, doi. 10.1002/ange.201707324

By:

Liu, Renhe;
Lyu, Xiaoxuan;
Batt, Sarah M;
Hsu, Mei‐Hui;
Harbut, Michael B;
Vilchèze, Catherine;
Cheng, Bo;
Ajayi, Kehinde;
Yang, Baiyuan;
Yang, Yun;
Guo, Hui;
Lin, Changyou;
Gan, Fei;
Wang, Chen;
Franzblau, Scott G.;
Jacobs, William R.;
Besra, Gurdyal S.;
Johnson, Eric F.;
Petrassi, Mike;
Chatterjee, Arnab K.

Publication type:

Article

Evaluation of gyrase B as a drug target in Mycobacterium tuberculosis.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2012, v. 67, n. 2, p. 415, doi. 10.1093/jac/dkr449

By:

Chopra, Sidharth;
Matsuyama, Karen;
Tran, Tran;
Malerich, Jeremiah P.;
Wan, Baojie;
Franzblau, Scott G.;
Lun, Shichun;
Guo, Haidan;
Maiga, Mariama C.;
Bishai, William R.;
Madrid, Peter B.

Publication type:

Article

In vitro and in vivo antimycobacterial activities of ketone and amide derivatives of quinoxaline 1,4-di-N-oxide.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2008, v. 62, n. 3, p. 547, doi. 10.1093/jac/dkn214

By:

Raquel Villar;
Esther Vicente;
Beatriz Solano;
Silvia Pérez-Silanes;
Ignacio Aldana;
Joseph A. Maddry;
Anne J. Lenaerts;
Scott G. Franzblau;
Sang-Hyun Cho;
Antonio Monge;
Robert C. Goldman

Publication type:

Article

Targeted Antitubercular Peptide Nanocarriers Prepared by Flash NanoPrecipitation with Hydrophobic Ion Pairing.

Published in:

Advanced Materials Technologies, 2022, v. 7, n. 11, p. 1, doi. 10.1002/admt.202101748

By:

Ristroph, Kurt D.;
McManus, Simon A.;
Shetye, Gauri;
Cho, Sang Hyun;
Lee, Dennis;
Szekely, Zoltan;
Sinko, Patrick J.;
Franzblau, Scott G.;
Prud'homme, Robert K.

Publication type:

Article

Microbiological Screening of 5-Functionalized Pyrazoles for the Future Development of Optimized Pyrazole-Based Delivery Systems.

Published in:

Pharmaceutics, 2022, v. 14, n. 9, p. N.PAG, doi. 10.3390/pharmaceutics14091770

By:

Brullo, Chiara;
Caviglia, Debora;
Spallarossa, Andrea;
Alfei, Silvana;
Franzblau, Scott G.;
Tasso, Bruno;
Schito, Anna Maria

Publication type:

Article

Synthesis and Structure–Activity Relationships for the Anti-Mycobacterial Activity of 3-Phenyl- N -(Pyridin-2-ylmethyl)Pyrazolo[1,5- a ]Pyrimidin-7-Amines.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 9, p. N.PAG, doi. 10.3390/ph15091125

By:

Sutherland, Hamish S.;
Choi, Peter J.;
Lu, Guo-Liang;
Giddens, Anna C.;
Tong, Amy S. T.;
Franzblau, Scott G.;
Cooper, Christopher B.;
Palmer, Brian D.;
Denny, William A.

Publication type:

Article

glpx Gene in Mycobacterium tuberculosis Is Required for In Vitro Gluconeogenic Growth and In Vivo Survival.

Published in:

PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0138436

By:

Gutka, Hiten J.;
Wang, Yuehong;
Franzblau, Scott G.;
Movahedzadeh, Farahnaz

Publication type:

Article

In Vitro and In Vivo Activities of Ruthenium(II) Phosphine/Diimine/Picolinate Complexes (SCAR) against <i>Mycobacterium tuberculosis</i>

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064242

By:

Pavan, Fernando R.;
Poelhsitz, Gustavo V.;
da Cunha, Lucas V. P.;
Barbosa, Marilia I. F.;
Leite, Sergio R. A.;
Batista, Alzir A.;
Cho, Sang H.;
Franzblau, Scott G.;
de Camargo, Mariana S.;
Resende, Flávia A.;
Varanda, Eliana A.;
Leite, Clarice Q. F.

Publication type:

Article

Enhancing Hit Identification in <i>Mycobacterium tuberculosis</i> Drug Discovery Using Validated Dual-Event Bayesian Models

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063240

By:

Ekins, Sean;
Reynolds, Robert C.;
Franzblau, Scott G.;
Wan, Baojie;
Freundlich, Joel S.;
Bunin, Barry A.

Publication type:

Article

Improved BM212 MmpL3 Inhibitor Analogue Shows Efficacy in Acute Murine Model of Tuberculosis Infection.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056980

By:

Poce, Giovanna;
Bates, Robert H.;
Alfonso, Salvatore;
Cocozza, Martina;
Porretta, Giulio Cesare;
Ballell, Lluís;
Rullas, Joaquin;
Ortega, Fátima;
De Logu, Alessandro;
Agus, Emanuela;
La Rosa, Valentina;
Pasca, Maria Rosalia;
De Rossi, Edda;
Wae, Baojie;
Franzblau, Scott G.;
Manetti, Fabrizio;
Botta, Maurizio;
Biava, Mariangela

Publication type:

Article

Carcinogenic effects of N-nitroso-3- (substituted phenylimino)-indolin-2-one derivatives.

Published in:

Journal of Pharmacy & Bioallied Sciences, 2012, v. 4, n. 3, p. 207, doi. 10.4103/0975-7406.99035

By:

Kumarasamy, Murali;
Theivendren, Panneerselvam;
Govindarajan, Rousso;
Franzblau, Scott G.;
Ramalingam, Kirthiga

Publication type:

Article

Antituberculotic and Antiprotozoal Activities of Primin, a Natural Benzoquinone: In vitro and in vivo Studies.

Published in:

Chemistry & Biodiversity, 2006, v. 3, n. 11, p. 1230, doi. 10.1002/cbdv.200690124

By:

Tasdemir, Deniz;
Brun, Reto;
Yardley, Vanessa;
Franzblau, Scott G.;
Rüedi, Peter

Publication type:

Article

In vitro susceptibility of Mycobacterium tuberculosis to extracts of Eucalyptus camaldulensis and Eucalyptus torelliana and isolated compounds.

Published in:

Pharmaceutical Biology, 2012, v. 50, n. 1, p. 92, doi. 10.3109/13880209.2011.625953

By:

Lawal, Temitope O.;
Adeniyi, Bolanle A.;
Adegoke, Aremu O.;
Franzblau, Scott G.;
Mahady, Gail B.

Publication type:

Article

Biological evaluation of plants of Laos used in the treatment of tuberculosis in Lao traditional medicine.

Published in:

Pharmaceutical Biology, 2009, v. 47, n. 1, p. 26, doi. 10.1080/13880200802398002

By:

Elkington, Bethany G.;
Southavong, Bounhong;
Sydara, Kongmany;
Souliya, Onevilay;
Vanthanouvong, Manoluck;
Nettavong, Kongdeuane;
Thammachack, Bounleuth;
Pak, Dennis H.;
Riley, Mary C.;
Franzblau, Scott G.;
Soejarto, D. Doel

Publication type:

Article

Vaccination with Bacille-Calmette Guérin Promotes Mycobacterial Control in Guinea Pig Macrophages Infected In Vivo.

Published in:

Journal of Infectious Diseases, 2008, v. 198, n. 5, p. 768, doi. 10.1086/590436

By:

Ly, Lan H.;
Barhoumi, Rola;
Cho, Sang H.;
Franzblau, Scott G.;
McMurray, David N.

Publication type:

Article

Strategies in anti-Mycobacterium tuberculosis drug discovery based on phenotypic screening.

Published in:

Journal of Antibiotics, 2019, v. 72, n. 10, p. 719, doi. 10.1038/s41429-019-0205-9

By:

Grzelak, Edyta M.;
Choules, Mary P.;
Gao, Wei;
Cai, Geping;
Wan, Baojie;
Wang, Yuehong;
McAlpine, James B.;
Cheng, Jinhua;
Jin, Yingyu;
Lee, Hanki;
Suh, Joo-Won;
Pauli, Guido F.;
Franzblau, Scott G.;
Jaki, Birgit U.;
Cho, Sanghyun

Publication type:

Article

Discovery of a capuramycin analog that kills nonreplicating Mycobacterium tuberculosis and its synergistic effects with translocase I inhibitors.

Published in:

Journal of Antibiotics, 2015, v. 68, n. 4, p. 271, doi. 10.1038/ja.2014.133

By:

Siricilla, Shajila;
Mitachi, Katsuhiko;
Wan, Bajoie;
Franzblau, Scott G;
Kurosu, Michio

Publication type:

Article