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A Triple Combination of Targeting Ligands Increases the Penetration of Nanoparticles across a Blood-Brain Barrier Culture Model.
- Published in:
- Pharmaceutics, 2022, v. 14, n. 1, p. 86, doi. 10.3390/pharmaceutics14010086
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- Publication type:
- Article
Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state.
- Published in:
- 2022
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- Publication type:
- journal article
Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids.
- Published in:
- Cell & Tissue Research, 2020, v. 382, n. 3, p. 463, doi. 10.1007/s00441-020-03249-y
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- Publication type:
- Article
The RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs.
- Published in:
- Nucleic Acids Research, 2015, v. 43, n. 5, p. 2638, doi. 10.1093/nar/gkv138
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- Publication type:
- Article
A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1–miRNA feedback loop.
- Published in:
- Nucleic Acids Research, 2013, v. 41, n. 6, p. 3699, doi. 10.1093/nar/gkt070
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- Publication type:
- Article
Anti-inflammatory treatment induced regenerative oligodendrogenesis in parkinsonian mice.
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- Stem Cell Research & Therapy, 2012, v. 3, n. 4, p. 124, doi. 10.1186/scrt124
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- Publication type:
- Article
Neural Stem Cells Maintain Their Stemness through Protein Kinase C ζ-Mediated Inhibition of TRIM32.
- Published in:
- Stem Cells, 2011, v. 29, n. 9, p. 1437, doi. 10.1002/stem.687
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- Publication type:
- Article
Non-proteolytic ubiquitination of OTULIN regulates NF-κB signaling pathway.
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- Journal of Molecular Cell Biology, 2020, v. 12, n. 3, p. 163, doi. 10.1093/jmcb/mjz081
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- Publication type:
- Article
Derivation and Expansion Using Only Small Molecules of Human Neural Progenitors for Neurodegenerative Disease Modeling.
- Published in:
- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059252
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- Publication type:
- Article
Regrowing the Adult Brain: NF-κB Controls Functional Circuit Formation and Tissue Homeostasis in the Dentate Gyrus.
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- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0030838
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- Publication type:
- Article
TRIM32 Regulates Skeletal Muscle Stem Cell Differentiation and Is Necessary for Normal Adult Muscle Regeneration.
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- PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0030445
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- Publication type:
- Article
Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis.
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- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. 1, doi. 10.1186/s40478-019-0871-7
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- Publication type:
- Article
Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity.
- Published in:
- Acta Neuropathologica Communications, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40478-018-0554-9
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- Publication type:
- Article
Prox1 Is Required for Oligodendrocyte Cell Identity in Adult Neural Stem Cells of the Subventricular Zone.
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- Stem Cells, 2016, v. 34, n. 8, p. 2115, doi. 10.1002/stem.2374
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- Publication type:
- Article
Retraction: 'Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity'.
- Published in:
- EMBO Journal, 2014, v. 33, n. 24, p. 3012, doi. 10.15252/embj.201470130
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- Publication type:
- Article
Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity.
- Published in:
- EMBO Journal, 2007, v. 26, n. 5, p. 1410, doi. 10.1038/sj.emboj.7601580
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- Publication type:
- Article
JAM-A is a novel surface marker for NG2-Glia in the adult mouse brain.
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- BMC Neuroscience, 2010, v. 11, p. 27, doi. 10.1186/1471-2202-11-27
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- Publication type:
- Article
CLN3 deficiency leads to neurological and metabolic perturbations during early development.
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- Life Science Alliance, 2024, v. 7, n. 3, p. 1, doi. 10.26508/lsa.202302057
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- Publication type:
- Article
3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing.
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- Advanced Science, 2019, v. 6, n. 1, p. N.PAG, doi. 10.1002/advs.201800927
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- Publication type:
- Article
Automated high-throughput high-content autophagy and mitophagy analysis platform.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-45917-2
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- Publication type:
- Article
Quality Control Strategy for CRISPR-Cas9-Based Gene Editing Complicated by a Pseudogene.
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- Frontiers in Genetics, 2020, v. 10, p. 1, doi. 10.3389/fgene.2019.01297
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- Publication type:
- Article
Guidelines for Fluorescent Guided Biallelic HDR Targeting Selection With PiggyBac System Removal for Gene Editing.
- Published in:
- Frontiers in Genetics, 2019, p. N.PAG, doi. 10.3389/fgene.2019.00190
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- Publication type:
- Article
The neural stem cell fate determinant TRIM32 regulates complex behavioral traits.
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- Frontiers in Cellular Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fncel.2015.00075
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- Publication type:
- Article
Gene regulatory network analysis reveals differences in site-specific cell fate determination in mammalian brain.
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- Frontiers in Cellular Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fncel.2014.00437
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- Publication type:
- Article
Impaired neuron differentiation in GBA-associated Parkinson's disease is linked to cell cycle defects in organoids.
- Published in:
- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00616-8
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- Publication type:
- Article
6-hydroxydopamine-induced Parkinson's disease-like degeneration generates acute microgliosis and astrogliosis in the nigrostriatal system but no bioluminescence imaging-detectable alteration in adult neurogenesis.
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- European Journal of Neuroscience, 2016, v. 43, n. 10, p. 1352, doi. 10.1111/ejn.13232
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- Publication type:
- Article
The E3-ubiquitin ligase TRIM2 regulates neuronal polarization.
- Published in:
- Journal of Neurochemistry, 2011, v. 117, n. 1, p. 29, doi. 10.1111/j.1471-4159.2010.06971.x
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- Publication type:
- Article
TRIM32 Senses and Restricts Influenza A Virus by Ubiquitination of PB1 Polymerase.
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- PLoS Pathogens, 2015, v. 11, n. 6, p. 1, doi. 10.1371/journal.ppat.1004960
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- Publication type:
- Article
Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.87081
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- Publication type:
- Article
PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-84278-7
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- Publication type:
- Article
Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening.
- Published in:
- Scientific Reports, 2021, v. 10, n. 1, p. 1, doi. 10.1038/s41598-021-81129-3
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- Publication type:
- Article
Impaired mitochondrial–endoplasmic reticulum interaction and mitophagy in Miro1-mutant neurons in Parkinson's disease.
- Published in:
- Human Molecular Genetics, 2020, v. 29, n. 8, p. 1353, doi. 10.1093/hmg/ddaa066
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- Publication type:
- Article
Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein.
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- Human Molecular Genetics, 2019, v. 28, n. 1, p. 31, doi. 10.1093/hmg/ddy326
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- Publication type:
- Article
Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling.
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- Cerebral Cortex, 2020, v. 30, n. 5, p. 3240, doi. 10.1093/cercor/bhz306
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- Publication type:
- Article
Abundant Occurrence of Basal Radial Glia in the Subventricular Zone of Embryonic Neocortex of a Lissencephalic Primate, the Common Marmoset Callithrix jacchus.
- Published in:
- Cerebral Cortex, 2012, v. 22, n. 2, p. 469, doi. 10.1093/cercor/bhr301
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- Publication type:
- Article
The Future of Parkinson's Disease Research: A New Paradigm of Human Specific Investigation Is Necessary... and Possible.
- Published in:
- Altex, 2022, v. 39, n. 4, p. 694, doi. 10.14573/altex.2203161
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- Publication type:
- Article
Advanced Good Cell Culture Practice for Human Primary, Stem Cell-Derived and Organoid Models as well as Microphysiological Systems.
- Published in:
- Altex, 2018, v. 35, n. 3, p. 353, doi. 10.14573/altex.1710081
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- Publication type:
- Article
Mitochondrial and Clearance Impairment in p.D620N VPS35 Patient‐Derived Neurons.
- Published in:
- Movement Disorders, 2021, v. 36, n. 3, p. 704, doi. 10.1002/mds.28365
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- Publication type:
- Article
A human stem cell-derived test system for agents modifying neuronal N-methyl-d-aspartate-type glutamate receptor Ca2+-signalling.
- Published in:
- Archives of Toxicology, 2021, v. 95, n. 5, p. 1703, doi. 10.1007/s00204-021-03024-0
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- Publication type:
- Article
Treating Parkinson's Disease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Administration.
- Published in:
- Cells (2073-4409), 2023, v. 12, n. 21, p. 2565, doi. 10.3390/cells12212565
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- Publication type:
- Article
Targeting Human Endothelial Cells with Glutathione and Alanine Increases the Crossing of a Polypeptide Nanocarrier through a Blood–Brain Barrier Model and Entry to Human Brain Organoids.
- Published in:
- Cells (2073-4409), 2023, v. 12, n. 3, p. 503, doi. 10.3390/cells12030503
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- Publication type:
- Article
The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity.
- Published in:
- Nature Neuroscience, 2004, v. 7, n. 9, p. 923, doi. 10.1038/nn1295
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- Publication type:
- Article
The majority of newly generated cells in the adult mouse substantia nigra express low levels of Doublecortin, but their proliferation is unaffected by 6- OHDA-induced nigral lesion or Minocycline-mediated inhibition of neuroinflammation.
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- European Journal of Neuroscience, 2013, v. 38, n. 5, p. 2684, doi. 10.1111/ejn.12269
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- Publication type:
- Article
Transition metal dichalcogenides to optimize the performance of peptide-imprinted conductive polymers as electrochemical sensors.
- Published in:
- Microchimica Acta, 2021, v. 188, n. 6, p. 1, doi. 10.1007/s00604-021-04850-w
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- Publication type:
- Article
Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality.
- Published in:
- Glia, 2022, v. 70, n. 7, p. 1267, doi. 10.1002/glia.24167
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- Publication type:
- Article
Environmental enrichment and physical exercise revert behavioral and electrophysiological impairments caused by reduced adult neurogenesis.
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- Hippocampus, 2017, v. 27, n. 1, p. 36, doi. 10.1002/hipo.22669
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- Publication type:
- Article
Omics data integration suggests a potential idiopathic Parkinson's disease signature.
- Published in:
- Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-05548-w
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- Publication type:
- Article
Automated microfluidic cell culture of stem cell derived dopaminergic neurons.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-34828-3
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- Publication type:
- Article
Structural Plasticity of Dopaminergic Neurons Requires the Activation of the D3R-nAChR Heteromer and the PI3K-ERK1/2/Akt-Induced Expression of c-Fos and p70S6K Signaling Pathway.
- Published in:
- Molecular Neurobiology, 2022, v. 59, n. 4, p. 2129, doi. 10.1007/s12035-022-02748-z
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- Publication type:
- Article
Parkinson’s Disease-Associated Mutant LRRK2-Mediated Inhibition of miRNA Activity is Antagonized by TRIM32.
- Published in:
- Molecular Neurobiology, 2018, v. 55, n. 4, p. 3490, doi. 10.1007/s12035-017-0570-y
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- Publication type:
- Article