Works by Schuppert, Andreas

Results: 44

Future Medical Artificial Intelligence Application Requirements and Expectations of Physicians in German University Hospitals: Web-Based Survey.

Published in:

2021

By:

Maassen, Oliver;
Fritsch, Sebastian;
Palm, Julia;
Deffge, Saskia;
Kunze, Julian;
Marx, Gernot;
Riedel, Morris;
Schuppert, Andreas;
Bickenbach, Johannes

Publication type:

journal article

Translational learning from clinical studies predicts drug pharmacokinetics across patient populations.

Published in:

NPJ Systems Biology & Applications, 2017, v. 3, n. 1, p. N.PAG, doi. 10.1038/s41540-017-0012-5

By:

Krauss, Markus;
Hofmann, Ute;
Schafmayer, Clemens;
Igel, Svitlana;
Schlender, Jan;
Mueller, Christian;
Brosch, Mario;
von Schoenfels, Witigo;
Erhart, Wiebke;
Schuppert, Andreas;
Block, Michael;
Schaeffeler, Elke;
Boehmer, Gabriele;
Goerlitz, Linus;
Hoecker, Jan;
Lippert, Joerg;
Kerb, Reinhold;
Hampe, Jochen;
Kuepfer, Lars;
Schwab, Matthias

Publication type:

Article

PhysioSpace: Relating Gene Expression Experiments from Heterogeneous Sources Using Shared Physiological Processes.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077627

By:

Lenz, Michael;
Schuldt, Bernhard M.;
Müller, Franz-Josef;
Schuppert, Andreas

Publication type:

Article

Combination of a Proteomics Approach and Reengineering of Meso Scale Network Models for Prediction of Mode-of-Action for Tyrosine Kinase Inhibitors.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0053668

By:

Balabanov, Stefan;
Wilhelm, Thomas;
Venz, Simone;
Keller, Gunhild;
Scharf, Christian;
Pospisil, Heike;
Braig, Melanie;
Barett, Christine;
Bokemeyer, Carsten;
Walther, Reinhard;
Büimmendorf, Tim H.;
Schuppert, Andreas;
Hofer, Thomas

Publication type:

Article

Power-Laws and the Use of Pluripotent Stem Cell Lines.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0052068

By:

Schuldt, Bernhard M.;
Guhr, Anke;
Lenz, Michael;
Kobold, Sabine;
MacArthur, Ben D.;
Schuppert, Andreas;
Löser, Peter;
Müller, Franz-Josef

Publication type:

Article

Noisecut: a python package for noise-tolerant classification of binary data using prior knowledge integration and max-cut solutions.

Published in:

BMC Bioinformatics, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12859-024-05769-8

By:

Samadi, Moein E.;
Mirzaieazar, Hedieh;
Mitsos, Alexander;
Schuppert, Andreas

Publication type:

Article

A systematic atlas of chaperome deregulation topologies across the human cancer landscape.

Published in:

PLoS Computational Biology, 2018, v. 14, n. 1, p. 1, doi. 10.1371/journal.pcbi.1005890

By:

Hadizadeh Esfahani, Ali;
Sverchkova, Angelina;
Saez-Rodriguez, Julio;
Schuppert, Andreas A.;
Brehme, Marc

Publication type:

Article

Stimulation of L‐type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells.

Published in:

Stem Cells Translational Medicine, 2020, v. 9, n. 6, p. 697, doi. 10.1002/sctm.18-0180

By:

Jefri, Malvin;
Bell, Scott;
Peng, Huashan;
Hettige, Nuwan;
Maussion, Gilles;
Soubannier, Vincent;
Wu, Hanrong;
Silveira, Heika;
Theroux, Jean‐Francois;
Moquin, Luc;
Zhang, Xin;
Aouabed, Zahia;
Krishnan, Jeyashree;
O'Leary, Liam A.;
Antonyan, Lilit;
Zhang, Ying;
McCarty, Vincent;
Mechawar, Naguib;
Gratton, Alain;
Schuppert, Andreas

Publication type:

Article

FOXG1 targets BMP repressors and cell cycle inhibitors in human neural progenitor cells.

Published in:

Human Molecular Genetics, 2023, v. 32, n. 15, p. 2511, doi. 10.1093/hmg/ddad089

By:

Hettige, Nuwan C;
Fleming, Peter;
Semenak, Amelia;
Zhang, Xin;
Peng, Huashan;
Hagel, Marc-Daniel;
Théroux, Jean-François;
Zhang, Ying;
Ni, Anjie;
Jefri, Malvin;
Antonyan, Lilit;
Alsuwaidi, Shaima;
Schuppert, Andreas;
Stumpf, Patrick S;
Ernst, Carl

Publication type:

Article

Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4).

Published in:

Human Molecular Genetics, 2022, v. 31, n. 21, p. 3715, doi. 10.1093/hmg/ddac121

By:

Jefri, Malvin;
Zhang, Xin;
Stumpf, Patrick S;
Zhang, Li;
Peng, Huashan;
Hettige, Nuwan;
Theroux, Jean-Francois;
Aouabed, Zahia;
Wilson, Khadija;
Deshmukh, Shriya;
Antonyan, Lilit;
Ni, Anjie;
Alsuwaidi, Shaima;
Zhang, Ying;
Jabado, Nada;
Garcia, Benjamin A;
Schuppert, Andreas;
Bjornsson, Hans T;
Ernst, Carl

Publication type:

Article

Principal components analysis and the reported low intrinsic dimensionality of gene expression microarray data.

Published in:

Scientific Reports, 2016, p. 25696, doi. 10.1038/srep25696

By:

Lenz, Michael;
Müller, Franz-Josef;
Zenke, Martin;
Schuppert, Andreas

Publication type:

Article

Combined Population Dynamics and Entropy Modelling Supports Patient Stratification in Chronic Myeloid Leukemia.

Published in:

Scientific Reports, 2016, p. 24057, doi. 10.1038/srep24057

By:

Brehme, Marc;
Koschmieder, Steffen;
Montazeri, Maryam;
Copland, Mhairi;
Oehler, Vivian G.;
Radich, Jerald P.;
Brümmendorf, Tim H.;
Schuppert, Andreas

Publication type:

Article

Epigenetic Biomarker to Support Classification into Pluripotent and Non-Pluripotent Cells.

Published in:

Scientific Reports, 2015, p. 8973, doi. 10.1038/srep08973

By:

Lenz, Michael;
Goetzke, Roman;
Schenk, Arne;
Schubert, Claudia;
Veeck, Jürgen;
Hemeda, Hatim;
Koschmieder, Steffen;
Zenke, Martin;
Schuppert, Andreas;
Wagner, Wolfgang

Publication type:

Article

A model for the creep of oriented high-modulus fibers.

Published in:

Macromolecular Theory & Simulations, 1993, v. 2, n. 5, p. 643, doi. 10.1002/mats.1993.040020503

By:

Schuppert, Andreas A.

Publication type:

Article

Early and late stage MPN patients show distinct gene expression profiles in CD34<sup>+</sup> cells.

Published in:

Annals of Hematology, 2021, v. 100, n. 12, p. 2943, doi. 10.1007/s00277-021-04615-8

By:

Baumeister, Julian;
Maié, Tiago;
Chatain, Nicolas;
Gan, Lin;
Weinbergerova, Barbora;
de Toledo, Marcelo A. S.;
Eschweiler, Jörg;
Maurer, Angela;
Mayer, Jiri;
Kubesova, Blanka;
Racil, Zdenek;
Schuppert, Andreas;
Costa, Ivan;
Koschmieder, Steffen;
Brümmendorf, Tim H.;
Gezer, Deniz

Publication type:

Article

40. Prozeßmodellierung mit Hybridmodellen.

Published in:

Chemie Ingenieur Technik (CIT), 1998, v. 70, n. 9, p. 1090, doi. 10.1002/cite.330700944

By:

Schuppert, Andreas

Publication type:

Article

A modified Ising model of Barabási–Albert network with gene-type spins.

Published in:

Journal of Mathematical Biology, 2020, v. 81, n. 3, p. 769, doi. 10.1007/s00285-020-01518-6

By:

Krishnan, Jeyashree;
Torabi, Reza;
Schuppert, Andreas;
Napoli, Edoardo Di

Publication type:

Article

Monitoring individualized glucose levels predicts risk for bradycardia in type 2 diabetes patients with chronic kidney disease: a pilot study.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-81983-x

By:

Farhadi Ghalati, Pejman;
E. Samadi, Moein;
Verket, Marlo;
Balfanz, Paul;
Müller-Wieland, Dirk;
Jonas, Stephan;
Napp, Andreas;
Wanner, Christoph;
Ketteler, Markus;
Vassiliadou, Athina;
Heidenreich, Stefan;
Deserno, Thomas;
Hetzel, Gudrun;
Fliser, Danilo;
Kelm, Malte;
Floege, Jürgen;
Marx, Nikolaus;
Schuppert, Andreas

Publication type:

Article

Spike by spike frequency analysis of amperometry traces provides statistical validation of observations in the time domain.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-76665-7

By:

Krishnan, Jeyashree;
Lian, Zeyu;
Oomen, Pieter E.;
Amir-Aref, Mohaddeseh;
He, Xiulan;
Majdi, Soodabeh;
Schuppert, Andreas;
Ewing, Andrew

Publication type:

Article

Local identification of scalar hybrid models with tree structure.

Published in:

IMA Journal of Applied Mathematics, 2008, v. 73, n. 3, p. 449, doi. 10.1093/imamat/hxn011

By:

FIEDLER, BERNOLD;
SCHUPPERT, ANDREAS

Publication type:

Article

Bayesian Population Physiologically-Based Pharmacokinetic (PBPK) Approach for a Physiologically Realistic Characterization of Interindividual Variability in Clinically Relevant Populations.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0139423

By:

Krauss, Markus;
Tappe, Kai;
Schuppert, Andreas;
Kuepfer, Lars;
Goerlitz, Linus

Publication type:

Article

Effectiveness of extended shutdown measures during the ´Bundesnotbremse´ introduced in the third SARS-CoV-2 wave in Germany.

Published in:

Infection, 2021, v. 49, n. 6, p. 1331, doi. 10.1007/s15010-021-01713-7

By:

Schuppert, Andreas;
Polotzek, Katja;
Karschau, Jens;
Karagiannidis, Christian

Publication type:

Article

Development and validation of a reinforcement learning algorithm to dynamically optimize mechanical ventilation in critical care.

Published in:

NPJ Digital Medicine, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s41746-021-00388-6

By:

Peine, Arne;
Hallawa, Ahmed;
Bickenbach, Johannes;
Dartmann, Guido;
Fazlic, Lejla Begic;
Schmeink, Anke;
Ascheid, Gerd;
Thiemermann, Christoph;
Schuppert, Andreas;
Kindle, Ryan;
Celi, Leo;
Marx, Gernot;
Martin, Lukas

Publication type:

Article

Critical Transitions in Intensive Care Units: A Sepsis Case Study.

Published in:

2019

By:

Ghalati, Pejman F.;
Samal, Satya S.;
Bhat, Jayesh S.;
Deisz, Robert;
Marx, Gernot;
Schuppert, Andreas

Publication type:

Case Study

Developing an Artificial Intelligence-Based Representation of a Virtual Patient Model for Real-Time Diagnosis of Acute Respiratory Distress Syndrome.

Published in:

Diagnostics (2075-4418), 2023, v. 13, n. 12, p. 2098, doi. 10.3390/diagnostics13122098

By:

Barakat, Chadi S.;
Sharafutdinov, Konstantin;
Busch, Josefine;
Saffaran, Sina;
Bates, Declan G.;
Hardman, Jonathan G.;
Schuppert, Andreas;
Brynjólfsson, Sigurður;
Fritsch, Sebastian;
Riedel, Morris

Publication type:

Article

Analysis of Chest X-ray for COVID-19 Diagnosis as a Use Case for an HPC-Enabled Data Analysis and Machine Learning Platform for Medical Diagnosis Support.

Published in:

Diagnostics (2075-4418), 2023, v. 13, n. 3, p. 391, doi. 10.3390/diagnostics13030391

By:

Barakat, Chadi;
Aach, Marcel;
Schuppert, Andreas;
Brynjólfsson, Sigurður;
Fritsch, Sebastian;
Riedel, Morris

Publication type:

Article

Efficient reengineering of meso-scale topologies for functional networks in biomedical applications.

Published in:

Journal of Mathematics in Industry, 2011, v. 1, n. 1, p. 1, doi. 10.1186/2190-5983-1-6

By:

Schuppert, Andreas

Publication type:

Article

Epigenetic and Transcriptional Shifts in Human Neural Stem Cells after Reprogramming into Induced Pluripotent Stem Cells and Subsequent Redifferentiation.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 6, p. 3214, doi. 10.3390/ijms25063214

By:

Haubenreich, Carolin;
Lenz, Michael;
Schuppert, Andreas;
Peitz, Michael;
Koch, Philipp;
Zenke, Martin;
Brüstle, Oliver

Publication type:

Article

From hype to reality: data science enabling personalized medicine.

Published in:

2018

By:

Fröhlich, Holger;
Balling, Rudi;
Beerenwinkel, Niko;
Kohlbacher, Oliver;
Kumar, Santosh;
Lengauer, Thomas;
Maathuis, Marloes H.;
Moreau, Yves;
Murphy, Susan A.;
Przytycka, Teresa M.;
Rebhan, Michael;
Röst, Hannes;
Schuppert, Andreas;
Schwab, Matthias;
Spang, Rainer;
Stekhoven, Daniel;
Sun, Jimeng;
Weber, Andreas;
Ziemek, Daniel;
Zupan, Blaz

Publication type:

journal article

Methodological challenges in translational drug response modeling in cancer: A systematic analysis with FORESEE.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 4, p. 1, doi. 10.1371/journal.pcbi.1007803

By:

Schätzle, Lisa-Katrin;
Hadizadeh Esfahani, Ali;
Schuppert, Andreas

Publication type:

Article

FORESEE: a tool for the systematic comparison of translational drug response modeling pipelines.

Published in:

Bioinformatics, 2019, v. 35, n. 19, p. 3846, doi. 10.1093/bioinformatics/btz145

By:

Turnhoff, Lisa-Katrin;
Esfahani, Ali Hadizadeh;
Montazeri, Maryam;
Kusch, Nina;
Schuppert, Andreas

Publication type:

Article

Novel architecture for gated recurrent unit autoencoder trained on time series from electronic health records enables detection of ICU patient subgroups.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-30986-1

By:

Merkelbach, Kilian;
Schaper, Steffen;
Diedrich, Christian;
Fritsch, Sebastian Johannes;
Schuppert, Andreas

Publication type:

Article

A neural network assisted Metropolis adjusted Langevin algorithm.

Published in:

Monte Carlo Methods & Applications, 2020, v. 26, n. 2, p. 93, doi. 10.1515/mcma-2020-2060

By:

Müller, Christian;
Diedam, Holger;
Mrziglod, Thomas;
Schuppert, Andreas

Publication type:

Article

Markov-Chain Monte-Carlo methods and non-identifiabilities.

Published in:

Monte Carlo Methods & Applications, 2018, v. 24, n. 3, p. 203, doi. 10.1515/mcma-2018-0018

By:

Müller, Christian;
Weysser, Fabian;
Mrziglod, Thomas;
Schuppert, Andreas

Publication type:

Article

Enabling multiscale modeling in systems medicine.

Published in:

2014

By:

Wolkenhauer, Olaf;
Auffray, Charles;
Brass, Olivier;
Clairambault, Jean;
Deutsch, Andreas;
Drasdo, Dirk;
Gervasio, Francesco;
Preziosi, Luigi;
Maini, Philip;
Marciniak-Czochra, Anna;
Kossow, Christina;
Kuepfer, Lars;
Rateitschak, Katja;
Ramis-Conde, Ignacio;
Ribba, Benjamin;
Schuppert, Andreas;
Smallwood, Rod;
Stamatakos, Georgios;
Winter, Felix;
Byrne, Helen

Publication type:

Opinion

A training strategy for hybrid models to break the curse of dimensionality.

Published in:

PLoS ONE, 2022, v. 17, n. 9, p. 1, doi. 10.1371/journal.pone.0274569

By:

E. Samadi, Moein;
Kiefer, Sandra;
Fritsch, Sebastian Johaness;
Bickenbach, Johannes;
Schuppert, Andreas

Publication type:

Article

Few inputs can reprogram biological networks.

Published in:

Nature, 2011, v. 478, n. 7369, p. E4, doi. 10.1038/nature10543

By:

Müller, Franz-Josef;
Schuppert, Andreas

Publication type:

Article

Intensivbettenbedarf für COVID‑19 im Herbst/Winter 2021: Simulation unterschiedlicher Szenarien unter Berücksichtigung von Inzidenzen und Impfquoten.

Published in:

Medizinische Klinik: Intensivmedizin & Notfallmedizin, 2022, v. 117, n. 6, p. 439, doi. 10.1007/s00063-021-00862-9

By:

Schuppert, Andreas;
Weber-Carstens, Steffen;
Karagiannidis, Christian

Publication type:

Article

Dynamische Entwicklung der COVID-19-Intensivbelegung im Herbst/Winter 2021/22 in Abhängigkeit von den 7-Tage-Inzidenzen.

Published in:

Medizinische Klinik: Intensivmedizin & Notfallmedizin, 2022, v. 117, n. 3, p. 206, doi. 10.1007/s00063-022-00904-w

By:

Schuppert, Andreas;
Karagiannidis, Christian

Publication type:

Article

Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity.

Published in:

Nature Cell Biology, 2012, v. 14, n. 11, p. 1139, doi. 10.1038/ncb2603

By:

MacArthur, Ben D.;
Sevilla, Ana;
Lenz, Michel;
Müller, Franz-Josef;
Schuldt, Berhard M.;
Schuppert, Andreas A.;
Ridden, Sonya J.;
Stumpf, Patrick S.;
Fidalgo, Miguel;
Ma'ayan, Avi;
Wang, Jianlong;
Lemischka, Ihor R.

Publication type:

Article

6-month mortality and readmissions of hospitalized COVID-19 patients: A nationwide cohort study of 8,679 patients in Germany.

Published in:

PLoS ONE, 2021, v. 16, n. 8, p. 1, doi. 10.1371/journal.pone.0255427

By:

Günster, Christian;
Busse, Reinhard;
Spoden, Melissa;
Rombey, Tanja;
Schillinger, Gerhard;
Hoffmann, Wolfgang;
Weber-Carstens, Steffen;
Schuppert, Andreas;
Karagiannidis, Christian

Publication type:

Article

Two-step multi-omics modelling of drug sensitivity in cancer cell lines to identify driving mechanisms.

Published in:

PLoS ONE, 2020, v. 15, n. 11, p. 1, doi. 10.1371/journal.pone.0238961

By:

Kusch, Nina;
Schuppert, Andreas

Publication type:

Article

Plant PhysioSpace: a robust tool to compare stress response across plant species.

Published in:

Plant Physiology, 2021, v. 187, n. 3, p. 1795, doi. 10.1093/plphys/kiab325

By:

Esfahani, Ali Hadizadeh;
Maß, Janina;
Hallab, Asis;
Schuldt, Bernhard M.;
Nevarez, David;
Usadel, Björn;
Ott, Mark-Christoph;
Buer, Benjamin;
Schuppert, Andreas

Publication type:

Article

Biometric covariates and outcome in COVID-19 patients: are we looking close enough?

Published in:

BMC Infectious Diseases, 2021, v. 21, n. 1, p. 1, doi. 10.1186/s12879-021-06823-z

By:

Sharafutdinov, Konstantin;
Fritsch, Sebastian Johannes;
Marx, Gernot;
Bickenbach, Johannes;
Schuppert, Andreas

Publication type:

Article