Works by Schulze, Almut

Results: 35

Analysis of the transcriptional program induced by Raf in epithelial cells.

Published in:

2001

By:

Schulze, Almut;
Lehmann, Kerstin;
Jefferies, Harold B.;
McMahon, Martin;
Downward, Julian

Publication type:

Abstract

Lipid metabolism in cancer.

Published in:

FEBS Journal, 2012, v. 279, n. 15, p. 2610, doi. 10.1111/j.1742-4658.2012.08644.x

By:

Santos, Claudio R.;
Schulze, Almut

Publication type:

Article

Regulation of Metabolic Activity by p53.

Published in:

Metabolites (2218-1989), 2017, v. 7, n. 2, p. 21, doi. 10.3390/metabo7020021

By:

Flöter, Jessica;
Kaymak, Irem;
Schulze, Almut

Publication type:

Article

SOAT1: A Suitable Target for Therapy in High-Grade Astrocytic Glioma?

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 3726, doi. 10.3390/ijms23073726

By:

Löhr, Mario;
Härtig, Wolfgang;
Schulze, Almut;
Kroiß, Matthias;
Sbiera, Silviu;
Lapa, Constantin;
Mages, Bianca;
Strobel, Sabrina;
Hundt, Jennifer Elisabeth;
Bohnert, Simone;
Kircher, Stefan;
Janaki-Raman, Sudha;
Monoranu, Camelia-Maria

Publication type:

Article

Metformin Regulates the miR-205/VEGFA Axis in Renal Cell Carcinoma Cells: Exploring a Clinical Synergism with Tyrosine Kinase Inhibitors.

Published in:

Urologia Internationalis, 2024, v. 108, n. 1, p. 49, doi. 10.1159/000535025

By:

Krebs, Markus;
Kotlyar, Mischa J.;
Fahl, Julian;
Janaki Raman, Sudha;
Röhrig, Florian;
Marquardt, André;
Kübler, Hubert;
Kneitz, Burkhard;
Schulze, Almut;
Kalogirou, Charis

Publication type:

Article

An unexpected player in organ tropism: aspartate functions as signalling molecule to drive lung metastasis.

Published in:

Signal Transduction & Targeted Therapy, 2025, v. 10, n. 1, p. 1, doi. 10.1038/s41392-025-02189-9

By:

Vogel, Felix C. E.;
Schulze, Almut

Publication type:

Article

Beta-hydroxybutyrate (3-OHB) can influence the energetic phenotype of breast cancer cells, but does not impact their proliferation and the response to chemotherapy or radiation.

Published in:

Cancer & Metabolism, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40170-018-0180-9

By:

Bartmann, Catharina;
Janaki Raman, Sudha R.;
Flöter, Jessica;
Schulze, Almut;
Bahlke, Katrin;
Willingstorfer, Jana;
Strunz, Maria;
Wöckel, Achim;
Klement, Rainer J.;
Kapp, Michaela;
Djuzenova, Cholpon S.;
Otto, Christoph;
Kämmerer, Ulrike

Publication type:

Article

Acute systemic knockdown of Atg7 is lethal and causes pancreatic destruction in shRNA transgenic mice.

Published in:

Autophagy, 2022, v. 18, n. 12, p. 2880, doi. 10.1080/15548627.2022.2052588

By:

Mainz, Laura;
Sarhan, Mohamed A. F. E.;
Roth, Sabine;
Sauer, Ursula;
Kalogirou, Charis;
Eckstein, Markus;
Gerhard-Hartmann, Elena;
Seibert, Helen-Desiree;
Voelker, Hans-Ulrich;
Geppert, Carol;
Rosenwald, Andreas;
Eilers, Martin;
Schulze, Almut;
Diefenbacher, Markus;
Rosenfeldt, Mathias T.

Publication type:

Article

Protein kinase D1 deletion in adipocytes enhances energy dissipation and protects against adiposity.

Published in:

EMBO Journal, 2018, v. 37, n. 22, p. N.PAG, doi. 10.15252/embj.201899182

By:

Löffler, Mona C;
Mayer, Alexander E;
Trujillo Viera, Jonathan;
Loza Valdes, Angel;
El‐Merahbi, Rabih;
Ade, Carsten P;
Karwen, Till;
Schmitz, Werner;
Slotta, Anja;
Erk, Manuela;
Janaki‐Raman, Sudha;
Matesanz, Nuria;
Torres, Jorge L;
Marcos, Miguel;
Sabio, Guadalupe;
Eilers, Martin;
Schulze, Almut;
Sumara, Grzegorz

Publication type:

Article

Cathepsin Inhibition Modulates Metabolism and Polarization of Tumor-Associated Macrophages.

Published in:

Cancers, 2020, v. 12, n. 9, p. 2579, doi. 10.3390/cancers12092579

By:

Oelschlaegel, Diana;
Weiss Sadan, Tommy;
Salpeter, Seth;
Krug, Sebastian;
Blum, Galia;
Schmitz, Werner;
Schulze, Almut;
Michl, Patrick

Publication type:

Article

Modulation of Cellular Migration and Survival by c-Myc through the Downregulation of Urokinase (uPA) and uPA Receptor.

Published in:

Molecular & Cellular Biology, 2010, v. 30, n. 7, p. 21, doi. 10.1128/MCB.01442-09

By:

Alfano, Daniela;
Votta, Giuseppina;
Schulze, Almut;
Downward, Julian;
Caputi, Mario;
Stoppelli, Maria Patrizia;
Iaccarino, Ingram

Publication type:

Article

The Forkhead Transcription Factor FOXO3a Increases Phosphoinositide-3 Kinase/Akt Activity in Drug-Resistant Leukemic Cells through Induction of PIK3CA Expression.

Published in:

2008

By:

Hui, Rosaline C.-Y.;
Gomes, Ana R.;
Constantinidou, Demetra;
Costa, Joana R.;
Karadedou, Christina T.;
de Mattos, Sylvia Fernandez;
Wymann, Matthias P.;
Brosens, Jan J.;
Schulze, Almut;
Lam, Eric W.-F.

Publication type:

Abstract

Induction of Mxi1-SR by FOXO3a Contributes to Repression of Myc-Dependent Gene Expression.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 13, p. 26, doi. 10.1128/MCB.01789-06

By:

Delpuech, Oona;
Griffiths, Beatrice;
East, Philip;
Essafi, Abdelkader;
Lam, Eric W.-F.;
Burgering, Boudewijn;
Downward, Julian;
Schulze, Almut

Publication type:

Article

NFATc1 controls the cytotoxicity of CD8<sup>+</sup> T cells.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00612-6

By:

Klein-Hessling, Stefan;
Muhammad, Khalid;
Klein, Matthias;
Pusch, Tobias;
Rudolf, Ronald;
Flöter, Jessica;
Qureischi, Musga;
Beilhack, Andreas;
Vaeth, Martin;
Kummerow, Carsten;
Backes, Christian;
Schoppmeyer, Rouven;
Hahn, Ulrike;
Hoth, Markus;
Bopp, Tobias;
Berberich-Siebelt, Friederike;
Patra, Amiya;
Avots, Andris;
Müller, Nora;
Schulze, Almut

Publication type:

Article

Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis.

Published in:

Cancer & Metabolism, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40170-025-00400-7

By:

Daum, Ann-Kathrin;
Schlicker, Lisa;
Schneider, Marc A.;
Muley, Thomas;
Klingmüller, Ursula;
Schulze, Almut;
Thomas, Michael;
Christopoulos, Petros;
Sültmann, Holger

Publication type:

Article

Antagonism between FOXO and MYC regulates cellular powerhouse.

Published in:

Frontiers in Oncology, 2013, p. 1, doi. 10.3389/fonc.2013.00096

By:

Peck, Barrie;
Ferber, Emma C.;
Schulze, Almut

Publication type:

Article

Integrated Metabolomics and Transcriptomics Analysis of Monolayer and Neurospheres from Established Glioblastoma Cell Lines.

Published in:

Cancers, 2021, v. 13, n. 6, p. 1327, doi. 10.3390/cancers13061327

By:

Peixoto, Joana;
Janaki-Raman, Sudha;
Schlicker, Lisa;
Schmitz, Werner;
Walz, Susanne;
Winkelkotte, Alina M.;
Herold-Mende, Christel;
Soares, Paula;
Schulze, Almut;
Lima, Jorge;
Pollok, Karen E.;
Nagrath, Deepak

Publication type:

Article

Connecting lysosomes and mitochondria – a novel role for lipid metabolism in cancer cell death.

Published in:

Cell Communication & Signaling, 2019, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12964-019-0399-2

By:

Bartel, Karin;
Pein, Helmut;
Popper, Bastian;
Schmitt, Sabine;
Janaki-Raman, Sudha;
Schulze, Almut;
Lengauer, Florian;
Koeberle, Andreas;
Werz, Oliver;
Zischka, Hans;
Müller, Rolf;
Vollmar, Angelika M.;
von Schwarzenberg, Karin

Publication type:

Article

A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration.

Published in:

Molecular Systems Biology, 2014, v. 10, n. 11, p. n/a, doi. 10.15252/msb.20145746

By:

Yizhak, Keren;
Le Dévédec, Sylvia E;
Rogkoti, Vasiliki Maria;
Baenke, Franziska;
Boer, Vincent C;
Frezza, Christian;
Schulze, Almut;
Water, Bob;
Ruppin, Eytan

Publication type:

Article

A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration.

Published in:

Molecular Systems Biology, 2014, v. 10, n. 8, p. n/a, doi. 10.15252/msb.20134993

By:

Yizhak, Keren;
Le Dévédec, Sylvia E;
Rogkoti, Vasiliki Maria;
Baenke, Franziska;
Boer, Vincent C;
Frezza, Christian;
Schulze, Almut;
Water, Bob;
Ruppin, Eytan

Publication type:

Article

Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling.

Published in:

Molecular Systems Biology, 2013, v. 9, n. 1, p. 1, doi. 10.1038/msb.2012.74

By:

Eijkelenboom, Astrid;
Mokry, Michal;
de Wit, Elzo;
Smits, Lydia M;
Polderman, Paulien E;
van Triest, Miranda H;
van Boxtel, Ruben;
Schulze, Almut;
de Laat, Wouter;
Cuppen, Edwin;
Burgering, Boudewijn M T

Publication type:

Article

c-Myc plays a key role in IFN-γ-induced persistence of Chlamydia trachomatis.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.76721

By:

Vollmuth, Nadine;
Schlicker, Lisa;
Yongxia Guo;
Hovhannisyan, Pargev;
Janaki-Raman, Sudha;
Kurmasheva, Naziia;
Schmitz, Werner;
Schulze, Almut;
Stelzner, Kathrin;
Rajeeve, Karthika;
Rudel, Thomas

Publication type:

Article

Navigating gene expression using microarrays ? a technology review.

Published in:

Nature Cell Biology, 2001, v. 3, n. 8, p. E190, doi. 10.1038/35087138

By:

Schulze, Almut;
Downward, Julian

Publication type:

Article

The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling.

Published in:

Science Signaling, 2019, v. 12, n. 593, p. 1, doi. 10.1126/scisignal.aav9150

By:

Mayer, Alexander E.;
Löffler, Mona C.;
Loza Valdés, Angel E.;
Schmitz, Werner;
El-Merahbi, Rabih;
Viera, Jonathan Trujillo;
Erk, Manuela;
Zhang, Thianzhou;
Braun, Ursula;
Heikenwalder, Mathias;
Leitges, Michael;
Schulze, Almut;
Sumara, Grzegorz

Publication type:

Article

Glucosylceramide Synthase Inhibition in Combination with Aripiprazole Sensitizes Hepatocellular Cancer Cells to Sorafenib and Doxorubicin.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 1, p. 304, doi. 10.3390/ijms26010304

By:

Jennemann, Richard;
Volz, Martina;
Frias-Soler, Roberto Carlos;
Schulze, Almut;
Richter, Karsten;
Kaden, Sylvia;
Sandhoff, Roger

Publication type:

Article

Corrigendum: How cancer metabolism is tuned for proliferation and vulnerable to disruption.

Published in:

2013

By:

Schulze, Almut;
Harris, Adrian L.

Publication type:

Erratum

How cancer metabolism is tuned for proliferation and vulnerable to disruption.

Published in:

Nature, 2012, v. 491, n. 7424, p. 364, doi. 10.1038/nature11706

By:

Schulze, Almut;
Harris, Adrian L.

Publication type:

Article

A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00500-5

By:

Wang, Changwen;
Sun, Meng;
Shao, Chunxuan;
Schlicker, Lisa;
Zhuo, Yue;
Harim, Yassin;
Peng, Tianping;
Tian, Weili;
Stöffler, Nadja;
Schneider, Martin;
Helm, Dominic;
Chu, Youjun;
Fu, Beibei;
Jin, Xiaoliang;
Mallm, Jan-Philipp;
Mall, Moritz;
Wu, Yonghe;
Schulze, Almut;
Liu, Hai-Kun

Publication type:

Article

A fresh look at cancer metabolism in a historical setting.

Published in:

EMBO Reports, 2011, v. 12, n. 4, p. 289, doi. 10.1038/embor.2011.44

By:

Schulze, Almut

Publication type:

Article

Flux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism.

Published in:

Scientific Reports, 2015, p. 10738, doi. 10.1038/srep10738

By:

Gatto, Francesco;
Miess, Heike;
Schulze, Almut;
Nielsen, Jens

Publication type:

Article

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP.

Published in:

Oncogene, 2005, v. 24, n. 43, p. 6465, doi. 10.1038/sj.onc.1208802

By:

Porstmann, Thomas;
Griffiths, Beatrice;
Yuen-Li Chung;
Delpuech, Oona;
Griffiths, John R.;
Downward, Julian;
Schulze, Almut

Publication type:

Article

Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival.

Published in:

Journal of Pathology, 2015, v. 237, n. 2, p. 152, doi. 10.1002/path.4562

By:

Baenke, Franziska;
Dubuis, Sébastien;
Brault, Charlene;
Weigelt, Britta;
Dankworth, Beatrice;
Griffiths, Beatrice;
Jiang, Ming;
Mackay, Alan;
Saunders, Becky;
Spencer‐Dene, Bradley;
Ros, Susana;
Stamp, Gordon;
Reis‐Filho, Jorge S;
Howell, Michael;
Zamboni, Nicola;
Schulze, Almut

Publication type:

Article

Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways.

Published in:

Experimental & Molecular Medicine EMM, 2018, v. 50, n. 4, p. 1, doi. 10.1038/s12276-018-0065-6

By:

Snaebjornsson, Marteinn T;
Schulze, Almut

Publication type:

Article

Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways.

Published in:

Experimental & Molecular Medicine EMM, 2018, v. 50, n. 4, p. 1, doi. 10.1038/s12276-018-0065-6

By:

Snaebjornsson, Marteinn T;
Schulze, Almut

Publication type:

Article

Lipid desaturation - the next step in targeting lipogenesis in cancer?

Published in:

FEBS Journal, 2016, v. 283, n. 15, p. 2767, doi. 10.1111/febs.13681

By:

Peck, Barrie;
Schulze, Almut

Publication type:

Article