Found: 27
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Phase I Clinical Evaluation of Designed Ankyrin Repeat Protein [ 99m Tc]Tc(CO) 3 -(HE) 3 -Ec1 for Visualization of EpCAM-Expressing Lung Cancer.
- Published in:
- Cancers, 2024, v. 16, n. 16, p. 2815, doi. 10.3390/cancers16162815
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- Article
Targeted Delivery of HSP70 to Tumor Cells via Supramolecular Complex Based on HER2-Specific DARPin9_29 and the Barnase:Barstar Pair.
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- Cells (2073-4409), 2024, v. 13, n. 4, p. 317, doi. 10.3390/cells13040317
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- Article
Radionuclide Molecular Imaging of EpCAM Expression in Triple-Negative Breast Cancer Using the Scaffold Protein DARPin Ec1.
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- Molecules, 2020, v. 25, n. 20, p. 4719, doi. 10.3390/molecules25204719
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- Article
UCNP-based Photoluminescent Nanomedicines for Targeted Imaging and Theranostics of Cancer.
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- Molecules, 2020, v. 25, n. 18, p. 4302, doi. 10.3390/molecules25184302
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- Article
Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin–Toxin Fusion in a Pancreatic Cancer Xenograft Model.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2838, doi. 10.3390/ijms24032838
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- Article
Direct In Vivo Comparison of 99m Tc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 23, p. 15181, doi. 10.3390/ijms232315181
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- Article
Comparative Preclinical Evaluation of Peptide-Based Chelators for the Labeling of DARPin G3 with 99m Tc for Radionuclide Imaging of HER2 Expression in Cancer.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13443, doi. 10.3390/ijms232113443
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- Article
Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 9, p. 3310, doi. 10.3390/ijms21093310
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- Article
Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 12, p. 3047, doi. 10.3390/ijms20123047
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- Article
HER2-Specific Targeted Toxin DARPin-LoPE: Immunogenicity and Antitumor Effect on Intraperitoneal Ovarian Cancer Xenograft Model.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 10, p. 2399, doi. 10.3390/ijms20102399
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- Article
Preclinical Evaluation of HER2-Targeting DARPin G3: Impact of Albumin-Binding Domain (ABD) Fusion.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 8, p. 4246, doi. 10.3390/ijms25084246
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- Article
Visualization of epithelial cell adhesion molecule-expressing renal cell carcinoma xenografts using designed ankyrin repeat protein Ec1 labelled with <sup>99m</sup>Tc and <sup>125</sup>I.
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- Oncology Letters, 2023, v. 25, n. 1, p. N.PAG
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- Article
Phase I trial of <sup>99m</sup>Tc-(HE)3-G3, a DARPin-based probe for imaging of HER2 expression in breast cancer.
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- Journal of Nuclear Medicine, 2021, v. 62, n. 12, p. 1, doi. 10.2967/jnumed.121.262542
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- Article
Phase I trial of <sup>99m</sup>Tc-(HE)3-G3, a DARPin-based probe for imaging of HER2 expression in breast cancer.
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- Journal of Nuclear Medicine, 2021, v. 62, n. 11, p. 1, doi. 10.2967/jnumed.121.262542
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- Publication type:
- Article
Phase I trial of <sup>99m</sup>Tc-(HE)<sub>3</sub>-G3, a DARPin-based probe for imaging of HER2 expression in breast cancer.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 10, p. 1, doi. 10.2967/jnumed.121.262542
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- Publication type:
- Article
Phase I trial of <sup>99m</sup>Tc-(HE)<sub>3</sub>-G3, a DARPin-based probe for imaging of HER2 expression in breast cancer.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 8, p. 1, doi. 10.2967/jnumed.121.262542
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- Publication type:
- Article
Optimal composition and position of histidine-containing tags improves biodistribution of <sup>99m</sup>Tc-labeled DARPin G3.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-45795-8
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- Article
Anti‐CD63‐Oligonucleotide Functionalized Magnetic Beads for the Rapid Isolation of Small Extracellular Vesicles and Detection of EpCAM and HER2 Membrane Receptors using DARPin Probes.
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- Analysis & Sensing, 2023, v. 3, n. 1, p. 1, doi. 10.1002/anse.202200059
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- Article
Determination of protein rotational correlation time from NMR relaxation data at various solvent viscosities.
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- Journal of Biomolecular NMR, 2004, v. 30, n. 4, p. 431, doi. 10.1007/s10858-004-4242-7
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- Article
On the prevention of kidney uptake of radiolabeled DARPins.
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- EJNMMI Research, 2020, v. 10, n. 1, p. 1, doi. 10.1186/s13550-020-0599-1
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- Article
Direct Intra-Patient Comparison of Scaffold Protein-Based Tracers, [ 99m Tc]Tc-ADAPT6 and [ 99m Tc]Tc-(HE) 3 -G3, for Imaging of HER2-Positive Breast Cancer.
- Published in:
- Cancers, 2023, v. 15, n. 12, p. 3149, doi. 10.3390/cancers15123149
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- Article
Imaging-Guided Therapy Simultaneously Targeting HER2 and EpCAM with Trastuzumab and EpCAM-Directed Toxin Provides Additive Effect in Ovarian Cancer Model.
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- Cancers, 2021, v. 13, n. 16, p. 3939, doi. 10.3390/cancers13163939
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- Article
Influence of the Position and Composition of Radiometals and Radioiodine Labels on Imaging of Epcam Expression in Prostate Cancer Model Using the DARPin Ec1.
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- Cancers, 2021, v. 13, n. 14, p. 3589, doi. 10.3390/cancers13143589
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- Article
Epithelial cell adhesion molecule-targeting designed ankyrin repeat protein-toxin fusion Ec1-LoPE exhibits potent cytotoxic action in prostate cancer cells.
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- Oncology Reports, 2022, v. 47, n. 5, p. 1, doi. 10.3892/or.2022.8305
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- Article
Penetration Efficiency of Antitumor Agents in Ovarian Cancer Spheroids: The Case of Recombinant Targeted Toxin DARPin-LoPE and the Chemotherapy Drug, Doxorubicin.
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- Pharmaceutics, 2019, v. 11, n. 5, p. 219, doi. 10.3390/pharmaceutics11050219
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- Article
Towards structure determination of neurotoxin II bound to nicotinic acetylcholine receptor: a solid-state NMR approach
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- FEBS Letters, 2004, v. 564, n. 3, p. 319, doi. 10.1016/S0014-5793(04)00252-2
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- Article
Increased stability of human growth hormone with reduced lactogenic potency
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- FEBS Letters, 2002, v. 528, n. 1-3, p. 257, doi. 10.1016/S0014-5793(02)03325-2
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- Article