Works by Schueler, Kathryn L.

Results: 24

Increased transport of acetyl‐CoA into the endoplasmic reticulum causes a progeria‐like phenotype.

Published in:

Aging Cell, 2018, v. 17, n. 5, p. 1, doi. 10.1111/acel.12820

By:

Peng, Yajing;
Shapiro, Samantha L.;
Banduseela, Varuna C.;
Dieterich, Inca A.;
Hewitt, Kyle J.;
Bresnick, Emery H.;
Kong, Guangyao;
Zhang, Jing;
Schueler, Kathryn L.;
Keller, Mark P.;
Attie, Alan D.;
Hacker, Timothy A.;
Sullivan, Ruth;
Kielar‐Grevstad, Elle;
Arriola Apelo, Sebastian I.;
Lamming, Dudley W.;
Anderson, Rozalyn M.;
Puglielli, Luigi

Publication type:

Article

Novel regulators of islet function identified from genetic variation in mouse islet Ca<sup>2+</sup> oscillations.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.88189

By:

Emfinger, Christopher H.;
Clark, Lauren E.;
Yandell, Brian;
Schueler, Kathryn L.;
Simonett, Shane P.;
Stapleton, Donnie S.;
Mitok, Kelly A.;
Merrins, Matthew J.;
Keller, Mark P.;
Attie, Alan D.

Publication type:

Article

Genetic determinants of gut microbiota composition and bile acid profiles in mice.

Published in:

PLoS Genetics, 2019, v. 15, n. 8, p. 1, doi. 10.1371/journal.pgen.1008073

By:

Kemis, Julia H.;
Linke, Vanessa;
Barrett, Kelsey L.;
Boehm, Frederick J.;
Traeger, Lindsay L.;
Keller, Mark P.;
Rabaglia, Mary E.;
Schueler, Kathryn L.;
Stapleton, Donald S.;
Gatti, Daniel M.;
Churchill, Gary A.;
Amador-Noguez, Daniel;
Russell, Jason D.;
Yandell, Brian S.;
Broman, Karl W.;
Coon, Joshua J.;
Attie, Alan D.;
Rey, Federico E.

Publication type:

Article

Identification of the Bile Acid Transporter Slco1a6 as a Candidate Gene That Broadly Affects Gene Expression in Mouse Pancreatic Islets.

Published in:

Genetics, 2015, v. 201, n. 3, p. 1253, doi. 10.1534/genetics.115.179432

By:

Tian, Jianan;
Keller, Mark P.;
Oler, Angie T.;
Rabaglia, Mary E.;
Schueler, Kathryn L.;
Stapleton, Donald S.;
Broman, Aimee Teo;
Zhao, Wen;
Kendziorski, Christina;
Yandell, Brian S.;
Hagenbuch, Bruno;
Broman, Karl W.;
Attie, Alan D.

Publication type:

Article

Dimension Reduction for Mapping mRNA Abundance as Quantitative Traits.

Published in:

Genetics, 2003, v. 164, n. 4, p. 1607, doi. 10.1093/genetics/164.4.1607

By:

Hong Lan;
Stoehr, Jonathan P.;
Nadler, Samuel T.;
Schueler, Kathryn L.;
Yandell, Brian S.;
Attie, Alan D.

Publication type:

Article

Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-11047-6

By:

Niemi, Natalie M.;
Wilson, Gary M.;
Overmyer, Katherine A.;
Vögtle, F.-Nora;
Myketin, Lisa;
Lohman, Danielle C.;
Schueler, Kathryn L.;
Attie, Alan D.;
Meisinger, Chris;
Coon, Joshua J.;
Pagliarini, David J.

Publication type:

Article

Genetic Analysis of Obesity-Induced Diabetic Nephropathy in BTBR Mice.

Published in:

Diabetes, 2024, v. 73, n. 2, p. 312, doi. 10.2337/db23-0444

By:

Keller, Mark P.;
O’Connor, Chris;
Bitzer, Markus;
Schueler, Kathryn L.;
Stapleton, Donald S.;
Emfinger, Christopher H.;
Broman, Aimee Teo;
Hodgin, Jeffrey B.;
Attie, Alan D.

Publication type:

Article

An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets.

Published in:

Diabetes, 2023, v. 72, n. 11, p. 1621, doi. 10.2337/db23-0215

By:

Keller, Mark P.;
Hawes, Emily M.;
Schueler, Kathryn L.;
Stapleton, Donnie S.;
Mitok, Kelly A.;
Simonett, Shane P.;
Oeser, James K.;
Sampson, Leesa L.;
Attie, Alan D.;
Magnuson, Mark A.;
O'Brien, Richard M.

Publication type:

Article

The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets.

Published in:

PLoS Genetics, 2016, v. 12, n. 12, p. 1, doi. 10.1371/journal.pgen.1006466

By:

Keller, Mark P.;
Paul, Pradyut K.;
Rabaglia, Mary E.;
Stapleton, Donnie S.;
Schueler, Kathryn L.;
Broman, Aimee Teo;
Ye, Shuyun Isabella;
Leng, Ning;
Brandon, Christopher J.;
Neto, Elias Chaibub;
Plaisier, Christopher L.;
Simonett, Shane P.;
Kebede, Melkam A.;
Sheynkman, Gloria M.;
Klein, Mark A.;
Baliga, Nitin S.;
Smith, Lloyd M.;
Broman, Karl W.;
Yandell, Brian S.;
Kendziorski, Christina

Publication type:

Article

Lipidomic QTL in Diversity Outbred mice identifies a novel function for α/β hydrolase domain 2 (Abhd2) as an enzyme that metabolizes phosphatidylcholine and cardiolipin.

Published in:

PLoS Genetics, 2023, v. 19, n. 7, p. 1, doi. 10.1371/journal.pgen.1010713

By:

Price, Tara R.;
Stapleton, Donnie S.;
Schueler, Kathryn L.;
Norris, Marie K.;
Parks, Brian W.;
Yandell, Brian S.;
Churchill, Gary A.;
Holland, William L.;
Keller, Mark P.;
Attie, Alan D.

Publication type:

Article

INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants.

Published in:

Genome Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s13059-021-02450-8

By:

Dong, Chenyang;
Simonett, Shane P.;
Shin, Sunyoung;
Stapleton, Donnie S.;
Schueler, Kathryn L.;
Churchill, Gary A.;
Lu, Leina;
Liu, Xiaoxiao;
Jin, Fulai;
Li, Yan;
Attie, Alan D.;
Keller, Mark P.;
Keleş, Sündüz

Publication type:

Article

Positional Cloning of a Type 2 Diabetes Quantitative Trait Locus; Tomosyn-2, a Negative Regulator of Insulin Secretion.

Published in:

PLoS Genetics, 2011, v. 7, n. 10, p. 1, doi. 10.1371/journal.pgen.1002323

By:

Bhatnagar, Sushant;
Oler, Angie T.;
Rabaglia, Mary E.;
Stapleton, Donald S.;
Schueler, Kathryn L.;
Truchan, Nathan A.;
Worzella, Sara L.;
Stoehr, Jonathan P.;
Clee, Susanne M.;
Yandell, Brian S.;
Keller, Mark P.;
Thurmond, Debbie C.;
Attie, Alan D.

Publication type:

Article

Genetic Drivers of Pancreatic Islet Function.

Published in:

Genetics, 2018, v. 209, n. 1, p. 335, doi. 10.1534/genetics.118.300864

By:

Keller, Mark P.;
Gatti, Daniel M.;
Schueler, Kathryn L.;
Rabaglia, Mary E.;
Stapleton, Donnie S.;
Simecek, Petr;
Vincent, Matthew;
Allen, Sadie;
Broman, Aimee Teo;
Bacher, Rhonda;
Kendziorski, Christina;
Broman, Karl W.;
Yandell, Brian S.;
Churchill, Gary A.;
Attie, Alan D.

Publication type:

Article

Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice.

Published in:

Mammalian Genome, 2009, v. 20, n. 8, p. 476, doi. 10.1007/s00335-009-9217-2

By:

Enpeng Zhao;
Keller, Mark P.;
Rabaglia, Mary E.;
Oler, Angie T.;
Stapleton, Donnie S.;
Schueler, Kathryn L.;
Neto, Elias Chaibub;
Jee Young Moon;
Ping Wang;
I-Ming Wang;
Pek Yee Lum;
Ivanovska, Irena;
Cleary, Michele;
Greenawalt, Danielle;
John Tsang;
Choi, Youn Jeong;
Kleinhanz, Robert;
Shang, Jin;
Yun-Ping Zhou;
Howard, Andrew D.

Publication type:

Article

Genetic ablation of synaptotagmin-9 alters tomosyn-1 function to increase insulin secretion from pancreatic β-cells improving glucose clearance.

Published in:

FASEB Journal, 2023, v. 37, n. 8, p. e23075, doi. 10.1096/fj.202300291RR

By:

Rahman, Md Mostafizur;
Pathak, Asmita;
Schueler, Kathryn L.;
Alsharif, Haifa;
Michl, Ava;
Alexander, Justin;
Jeong-A Kim;
Bhatnagar, Sushant

Publication type:

Article

Cholecystokinin Overexpression in Isolated Islets Promotes β-Cell Proliferation in a Cck1r- and Cck2r-Independent Manner.

Published in:

Diabetes, 2007, v. 56, p. A417

By:

Raess, Philipp W.;
Lavine, Jeremy A.;
Presley, Brent K.;
Keller, Mark P.;
Rabaglia, Mary E.;
Schueler, Kathryn L.;
Fernandez, Luis A.;
Kopin, Alan S.;
Newgard, Christopher B.;
Attie, Alan D.

Publication type:

Article

Loss of Stearoyl-CoA Desaturase-1 Improves Insulin Sensitivity in Lean Mice but Worsens Diabetes in Leptin-Deficient Obese Mice.

Published in:

Diabetes, 2007, v. 56, n. 5, p. 1228, doi. 10.2337/db06-1142

By:

Flowers, Jessica B.;
Rabaglia, Mary E.;
Schueler, Kathryn L.;
Flowers, Matthew T.;
Lan, Hong;
Keller, Mark P.;
Ntambi, James M.;
Attie, Alan D.

Publication type:

Article

Distinguishing covariation from causation in diabetes: a lesson from the protein disulfide isomerase mRNA abundance trait.

Published in:

2004

By:

Lan, Hong;
Rabaglia, Mary E;
Schueler, Kathryn L;
Mata, Christine;
Yandell, Brian S;
Attie, Alan D

Publication type:

journal article

Identification of major quantitative trait loci controlling body weight variation in ob/ob mice.

Published in:

2004

By:

Stoehr, Jonathan P.;
Clee, Susanne M.;
Lan, Hong;
Boronenkov, Igor V.;
Schueler, Kathryn L.;
Byers, Jessica E.;
Yandell, Brian S.;
Attie, Alan D.

Publication type:

journal article

Distinguishing Covariation From Causation in Diabetes.

Published in:

Diabetes, 2004, v. 53, n. 1, p. 240, doi. 10.2337/diabetes.53.1.240

By:

Lan, Hong;
Rabaglia, Mary E.;
Schueler, Kathryn L.;
Mata, Christine;
Yandell, Brian S.;
Attie, Alan D.

Publication type:

Article

Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility.

Published in:

2003

By:

Lan, Hong;
Rabaglia, Mary E.;
Stoehr, Jonathan P.;
Nadler, Samuel T.;
Schueler, Kathryn L.;
Zou, Fei;
Yandell, Brian S.;
Attie, Alan D.

Publication type:

journal article

Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci.

Published in:

2000

By:

Stoehr, Jonathan P.;
Nadler, Samuel T.;
Schueler, Kathryn L.;
Rabaglia, Mary E.;
Yandell, Brian S.;
Metz, Stewart A.;
Attie, Alan D.;
Stoehr, J P;
Nadler, S T;
Schueler, K L;
Rabaglia, M E;
Yandell, B S;
Metz, S A;
Attie, A D

Publication type:

journal article

Combined Expression Trait Correlations and Expression Quantitative Trait Locus Mapping.

Published in:

PLoS Genetics, 2006, v. 2, n. 1, p. e6, doi. 10.1371/journal.pgen.0020006

By:

Hong Lan;
Meng Chen;
Flowers, Jessica B.;
Yandell, Brian S.;
Stapleton, Donnie S.;
Mata, Christine M.;
Mui, Eric Ton-Keen;
Flowers, Matthew T.;
Schueler, Kathryn L.;
Manly, Kenneth F.;
Williams, Robert W.;
Kendziorski, Christina;
Attie, Alan D.;
Gibson, Greg

Publication type:

Article

Gene loci associated with insulin secretion in islets from non-diabetic mice.

Published in:

2019

By:

Keller, Mark P.;
Rabaglia, Mary E.;
Schueler, Kathryn L.;
Stapleton, Donnie S.;
Gatti, Daniel M.;
Vincent, Matthew;
Mitok, Kelly A.;
Ziyue Wang;
Takanao Ishimura;
Simonett, Shane P.;
Emfinger, Christopher H.;
Das, Rahul;
Beck, Tim;
Kendziorski, Christina;
Broman, Karl W.;
Yandell, Brian S.;
Churchill, Gary A.;
Attie, Alan D.;
Wang, Ziyue;
Ishimura, Takanao

Publication type:

journal article