Works by Schrimpf, Daniel

Results: 82
    1
    2
    3

    Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature.

    Published in:
    NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00372-1
    By:
    • Sievers, Philipp;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Abdullaev, Zied;
    • Donson, Andrew M.;
    • Lake, Jessica A.;
    • Friedel, Dennis;
    • Scheie, David;
    • Tynninen, Olli;
    • Rauramaa, Tuomas;
    • Vepsäläinen, Kaisa L.;
    • Samuel, David;
    • Chapman, Rebecca;
    • Grundy, Richard G.;
    • Pajtler, Kristian W.;
    • Tauziède-Espariat, Arnault;
    • Métais, Alice;
    • Varlet, Pascale;
    • Snuderl, Matija;
    • Jacques, Thomas S.
    Publication type:
    Article
    4
    5

    Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis.

    Published in:
    Brain Pathology, 2018, v. 28, n. 5, p. 656, doi. 10.1111/bpa.12566
    By:
    • Korshunov, Andrey;
    • Chavez, Lukas;
    • Sharma, Tanvi;
    • Ryzhova, Marina;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Capper, David;
    • Sturm, Dominik;
    • Kool, Marcel;
    • Habel, Antje;
    • Kleinschmidt‐DeMasters, Bette K.;
    • Rosenblum, Marc;
    • Absalyamova, Oksana;
    • Golanov, Andrey;
    • Lichter, Peter;
    • Pfister, Stefan M.;
    • Jones, David T.W.;
    • Perry, Arie;
    • von Deimling, Andreas
    Publication type:
    Article
    6

    Melanotic Tumors of the Nervous System are Characterized by Distinct Mutational, Chromosomal and Epigenomic Profiles.

    Published in:
    Brain Pathology, 2015, v. 25, n. 2, p. 202, doi. 10.1111/bpa.12228
    By:
    • Koelsche, Christian;
    • Hovestadt, Volker;
    • Jones, David T. W.;
    • Capper, David;
    • Sturm, Dominik;
    • Sahm, Felix;
    • Schrimpf, Daniel;
    • Adeberg, Sebastian;
    • Böhmer, Katja;
    • Hagenlocher, Christian;
    • Mechtersheimer, Gunhild;
    • Kohlhof, Patricia;
    • Mühleisen, Helmut;
    • Beschorner, Rudi;
    • Hartmann, Christian;
    • Braczynski, Anne Kristin;
    • Mittelbronn, Michel;
    • Buslei, Rolf;
    • Becker, Albert;
    • Grote, Alexander
    Publication type:
    Article
    7
    8
    9

    Constitutional variants in PTEN: a frequent finding in patients with papillary tumors of the pineal region subtype B (PTPR-B) associated with isolated loss of chromosome 10.

    Published in:
    2025
    By:
    • Hirsch, Steffen;
    • Rahmanzade, Ramin;
    • Grund, Kerstin;
    • Sutter, Christian;
    • Schramm, Kathrin;
    • Selt, Florian;
    • Ecker, Jonas;
    • Jones, Barbara C.;
    • Schrimpf, Daniel;
    • Demmert, Martin;
    • Guerreiro Stücklin, Ana S.;
    • Hernaiz Driever, Pablo;
    • Mezger, Markus;
    • Brecht, Ines;
    • Adib, Sasan D.;
    • Brummel, Bastian;
    • Sturm, Dominik;
    • Dikow, Nicola;
    • Hempel, Maja;
    • Milde, Till
    Publication type:
    Letter
    10

    Identification of a putative molecular subtype of adult-type diffuse astrocytoma with recurrent MAPK pathway alterations.

    Published in:
    Acta Neuropathologica, 2024, v. 148, n. 1, p. 1, doi. 10.1007/s00401-024-02766-2
    By:
    • Sievers, Philipp;
    • Bielle, Franck;
    • Göbel, Kirsten;
    • Schrimpf, Daniel;
    • Nichelli, Lucia;
    • Mathon, Bertrand;
    • Appay, Romain;
    • Boldt, Henning B.;
    • Dohmen, Hildegard;
    • Selignow, Carmen;
    • Acker, Till;
    • Vicha, Ales;
    • Martinetto, Horacio;
    • Schweizer, Leonille;
    • Schüller, Ulrich;
    • Brandner, Sebastian;
    • Wesseling, Pieter;
    • Schmid, Simone;
    • Capper, David;
    • Abdullaev, Zied
    Publication type:
    Article
    11
    12

    Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics.

    Published in:
    Acta Neuropathologica, 2023, v. 146, n. 6, p. 853, doi. 10.1007/s00401-023-02638-1
    By:
    • Rahmanzade, Ramin;
    • Pfaff, Elke;
    • Banan, Rouzbeh;
    • Sievers, Philipp;
    • Suwala, Abigail K.;
    • Hinz, Felix;
    • Bogumil, Henri;
    • Cherkezov, Asan;
    • Kaan, Aras Fuat;
    • Schrimpf, Daniel;
    • Friedel, Dennis;
    • Göbel, Kirsten;
    • Keller, Felix;
    • Saenz-Sardà, Xavier;
    • Lossos, Alexander;
    • Sill, Martin;
    • Witt, Olaf;
    • Sakowitz, Oliver W.;
    • Korshunov, Andrey;
    • Reuss, David E.
    Publication type:
    Article
    13
    14

    Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions.

    Published in:
    Acta Neuropathologica, 2023, v. 145, n. 5, p. 667, doi. 10.1007/s00401-023-02558-0
    By:
    • Bogumil, Henri;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Ismer, Britta;
    • Blume, Christina;
    • Rahmanzade, Ramin;
    • Hinz, Felix;
    • Cherkezov, Asan;
    • Banan, Rouzbeh;
    • Friedel, Dennis;
    • Reuss, David E.;
    • Selt, Florian;
    • Ecker, Jonas;
    • Milde, Till;
    • Pajtler, Kristian W.;
    • Schittenhelm, Jens;
    • Hench, Jürgen;
    • Frank, Stephan;
    • Boldt, Henning B.;
    • Kristensen, Bjarne Winther
    Publication type:
    Article
    15

    Epigenetic profiling reveals a subset of pediatric-type glioneuronal tumors characterized by oncogenic gene fusions involving several targetable kinases.

    Published in:
    Acta Neuropathologica, 2022, v. 144, n. 5, p. 1049, doi. 10.1007/s00401-022-02492-7
    By:
    • Sievers, Philipp;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Friedel, Dennis;
    • Sturm, Dominik;
    • Gardberg, Maria;
    • Kurian, Kathreena M.;
    • Krskova, Lenka;
    • Vicha, Ales;
    • Schaller, Tina;
    • Hagel, Christian;
    • Abdullaev, Zied;
    • Aldape, Kenneth;
    • Jacques, Thomas S.;
    • Korshunov, Andrey;
    • Wick, Wolfgang;
    • Pfister, Stefan M.;
    • von Deimling, Andreas;
    • Jones, David T. W.;
    • Sahm, Felix
    Publication type:
    Article
    16
    17

    DNA-methylome-assisted classification of patients with poor prognostic subventricular zone associated IDH-wildtype glioblastoma.

    Published in:
    Acta Neuropathologica, 2022, v. 144, n. 1, p. 129, doi. 10.1007/s00401-022-02443-2
    By:
    • Adeberg, Sebastian;
    • Knoll, Maximilian;
    • Koelsche, Christian;
    • Bernhardt, Denise;
    • Schrimpf, Daniel;
    • Sahm, Felix;
    • König, Laila;
    • Harrabi, Semi Ben;
    • Hörner-Rieber, Juliane;
    • Verma, Vivek;
    • Bewerunge-Hudler, Melanie;
    • Unterberg, Andreas;
    • Sturm, Dominik;
    • Jungk, Christine;
    • Herold-Mende, Christel;
    • Wick, Wolfgang;
    • von Deimling, Andreas;
    • Debus, Juergen;
    • Rieken, Stefan;
    • Abdollahi, Amir
    Publication type:
    Article
    18

    Rapid-CNS<sup>2</sup>: rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study.

    Published in:
    Acta Neuropathologica, 2022, v. 143, n. 5, p. 609, doi. 10.1007/s00401-022-02415-6
    By:
    • Patel, Areeba;
    • Dogan, Helin;
    • Payne, Alexander;
    • Krause, Elena;
    • Sievers, Philipp;
    • Schoebe, Natalie;
    • Schrimpf, Daniel;
    • Blume, Christina;
    • Stichel, Damian;
    • Holmes, Nadine;
    • Euskirchen, Philipp;
    • Hench, Jürgen;
    • Frank, Stephan;
    • Rosenstiel-Goidts, Violaine;
    • Ratliff, Miriam;
    • Etminan, Nima;
    • Unterberg, Andreas;
    • Dieterich, Christoph;
    • Herold-Mende, Christel;
    • Pfister, Stefan M.
    Publication type:
    Article
    19

    Oligosarcomas, IDH-mutant are distinct and aggressive.

    Published in:
    Acta Neuropathologica, 2022, v. 143, n. 2, p. 263, doi. 10.1007/s00401-021-02395-z
    By:
    • Suwala, Abigail K.;
    • Felix, Marius;
    • Friedel, Dennis;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Hinz, Felix;
    • Hewer, Ekkehard;
    • Schweizer, Leonille;
    • Dohmen, Hildegard;
    • Pohl, Ute;
    • Staszewski, Ori;
    • Korshunov, Andrey;
    • Stein, Marco;
    • Wongsurawat, Thidathip;
    • Cheunsuacchon, Pornsuk;
    • Sathornsumetee, Sith;
    • Koelsche, Christian;
    • Turner, Clinton;
    • Le Rhun, Emilie;
    • Mühlebner, Angelika
    Publication type:
    Article
    20

    GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 6, p. 1065, doi. 10.1007/s00401-021-02369-1
    By:
    • Sievers, Philipp;
    • Stichel, Damian;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Sturm, Dominik;
    • Selt, Florian;
    • Ecker, Jonas;
    • Kazdal, Daniel;
    • Miele, Evelina;
    • Kranendonk, Mariëtte E. G.;
    • Tops, Bastiaan B. J.;
    • Kohlhof-Meinecke, Patricia;
    • Beschorner, Rudi;
    • Kramm, Christof M.;
    • Hasselblatt, Martin;
    • Reifenberger, Guido;
    • Capper, David;
    • Wesseling, Pieter;
    • Stenzinger, Albrecht;
    • Milde, Till
    Publication type:
    Article
    21

    Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 5, p. 827, doi. 10.1007/s00401-021-02356-6
    By:
    • Sievers, Philipp;
    • Henneken, Sophie C.;
    • Blume, Christina;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Okonechnikov, Konstantin;
    • Reuss, David E.;
    • Benzel, Julia;
    • Maaß, Kendra K.;
    • Kool, Marcel;
    • Sturm, Dominik;
    • Zheng, Tuyu;
    • Ghasemi, David R.;
    • Kohlhof-Meinecke, Patricia;
    • Cruz, Ofelia;
    • Suñol, Mariona;
    • Lavarino, Cinzia;
    • Ruf, Viktoria;
    • Boldt, Henning B.
    Publication type:
    Article
    22

    Molecular profiling of pediatric meningiomas shows tumor characteristics distinct from adult meningiomas.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 5, p. 873, doi. 10.1007/s00401-021-02351-x
    By:
    • Kirches, Elmar;
    • Sahm, Felix;
    • Korshunov, Andrey;
    • Bluecher, Christina;
    • Waldt, Natalie;
    • Kropf, Siegfried;
    • Schrimpf, Daniel;
    • Sievers, Philipp;
    • Stichel, Damian;
    • Schüller, Ulrich;
    • Schittenhelm, Jens;
    • Riemenschneider, Markus J.;
    • Karajannis, Matthias A.;
    • Perry, Arie;
    • Pietsch, Torsten;
    • Boekhoff, Svenja;
    • Capper, David;
    • Beck, Katja;
    • Paramasivam, Nagarajan;
    • Schlesner, Matthias
    Publication type:
    Article
    23

    Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 1, p. 179, doi. 10.1007/s00401-021-02302-6
    By:
    • Suwala, Abigail K.;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Maas, Sybren L. N.;
    • Sill, Martin;
    • Dohmen, Hildegard;
    • Banan, Rouzbeh;
    • Reinhardt, Annekathrin;
    • Sievers, Philipp;
    • Hinz, Felix;
    • Blattner-Johnson, Mirjam;
    • Hartmann, Christian;
    • Schweizer, Leonille;
    • Boldt, Henning B.;
    • Kristensen, Bjarne Winther;
    • Schittenhelm, Jens;
    • Wood, Matthew D.;
    • Chotard, Guillaume;
    • Bjergvig, Rolf;
    • Das, Anirban
    Publication type:
    Article
    24

    Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1.

    Published in:
    Acta Neuropathologica, 2021, v. 141, n. 2, p. 281, doi. 10.1007/s00401-020-02247-2
    By:
    • Sievers, Philipp;
    • Sill, Martin;
    • Blume, Christina;
    • Tauziede-Espariat, Arnault;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Reuss, David E.;
    • Dogan, Helin;
    • Hartmann, Christian;
    • Mawrin, Christian;
    • Hasselblatt, Martin;
    • Stummer, Walter;
    • Schick, Uta;
    • Hench, Jürgen;
    • Frank, Stephan;
    • Ketter, Ralf;
    • Schweizer, Leonille;
    • Schittenhelm, Jens;
    • Puget, Stéphanie;
    • Brandner, Sebastian
    Publication type:
    Article
    25

    Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis.

    Published in:
    Acta Neuropathologica, 2021, v. 141, n. 1, p. 85, doi. 10.1007/s00401-020-02243-6
    By:
    • Suwala, Abigail K.;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Kloor, Matthias;
    • Wefers, Annika K.;
    • Reinhardt, Annekathrin;
    • Maas, Sybren L. N.;
    • Kratz, Christian P.;
    • Schweizer, Leonille;
    • Hasselblatt, Martin;
    • Snuderl, Matija;
    • Abedalthagafi, Malak Sameer J.;
    • Abdullaev, Zied;
    • Monoranu, Camelia M.;
    • Bergmann, Markus;
    • Pekrun, Arnulf;
    • Freyschlag, Christian;
    • Aronica, Eleonora;
    • Kramm, Christof M.;
    • Hinz, Felix
    Publication type:
    Article
    26

    CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas.

    Published in:
    Acta Neuropathologica, 2020, v. 140, n. 3, p. 409, doi. 10.1007/s00401-020-02188-w
    By:
    • Sievers, Philipp;
    • Hielscher, Thomas;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Reuss, David E.;
    • Berghoff, Anna S.;
    • Neidert, Marian C.;
    • Wirsching, Hans-Georg;
    • Mawrin, Christian;
    • Ketter, Ralf;
    • Paulus, Werner;
    • Reifenberger, Guido;
    • Lamszus, Katrin;
    • Westphal, Manfred;
    • Etminan, Nima;
    • Ratliff, Miriam;
    • Herold-Mende, Christel;
    • Pfister, Stefan M.;
    • Jones, David T. W.;
    • Weller, Michael
    Publication type:
    Article
    27

    Infratentorial IDH-mutant astrocytoma is a distinct subtype.

    Published in:
    Acta Neuropathologica, 2020, v. 140, n. 4, p. 569, doi. 10.1007/s00401-020-02194-y
    By:
    • Banan, Rouzbeh;
    • Stichel, Damian;
    • Bleck, Anja;
    • Hong, Bujung;
    • Lehmann, Ulrich;
    • Suwala, Abigail;
    • Reinhardt, Annekathrin;
    • Schrimpf, Daniel;
    • Buslei, Rolf;
    • Stadelmann, Christine;
    • Ehlert, Karoline;
    • Prinz, Marco;
    • Acker, Till;
    • Schittenhelm, Jens;
    • Kaul, David;
    • Schweizer, Leonille;
    • Capper, David;
    • Harter, Patrick N.;
    • Etminan, Nima;
    • Jones, David T. W.
    Publication type:
    Article
    28

    Transcriptional profiling of medulloblastoma with extensive nodularity (MBEN) reveals two clinically relevant tumor subsets with VSNL1 as potent prognostic marker.

    Published in:
    Acta Neuropathologica, 2020, v. 139, n. 3, p. 583, doi. 10.1007/s00401-019-02102-z
    By:
    • Korshunov, Andrey;
    • Okonechnikov, Konstantin;
    • Sahm, Felix;
    • Ryzhova, Marina;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Ghasemi, David R.;
    • Pajtler, Kristian W.;
    • Antonelli, Manila;
    • Donofrio, Vittoria;
    • Mastronuzzi, Angela;
    • Rossi, Sabrina;
    • Camassei, Francesca Diomedi;
    • Buccoliero, Anna Maria;
    • Haberler, Christine;
    • Slavc, Irene;
    • Dahiya, Sonika;
    • Casalini, Belen;
    • Sievers, Philipp;
    • Meyer, Jochen
    Publication type:
    Article
    29
    30

    YAP1-fusions in pediatric NF2-wildtype meningioma.

    Published in:
    2020
    By:
    • Sievers, Philipp;
    • Chiang, Jason;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Paramasivam, Nagarajan;
    • Sill, Martin;
    • Gayden, Tenzin;
    • Casalini, Belen;
    • Reuss, David E.;
    • Dalton, James;
    • Pajtler, Kristian W.;
    • Hänggi, Daniel;
    • Herold-Mende, Christel;
    • Rushing, Elisabeth;
    • Korshunov, Andrey;
    • Mawrin, Christian;
    • Weller, Michael;
    • Schlesner, Matthias;
    • Wick, Wolfgang;
    • Jabado, Nada
    Publication type:
    Letter
    31

    Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course.

    Published in:
    Acta Neuropathologica, 2020, v. 139, n. 1, p. 193, doi. 10.1007/s00401-019-02078-w
    By:
    • Wefers, Annika K.;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Coras, Roland;
    • Pages, Mélanie;
    • Tauziède-Espariat, Arnault;
    • Varlet, Pascale;
    • Schwarz, Daniel;
    • Söylemezoglu, Figen;
    • Pohl, Ute;
    • Pimentel, José;
    • Meyer, Jochen;
    • Hewer, Ekkehard;
    • Japp, Anna;
    • Joshi, Abhijit;
    • Reuss, David E.;
    • Reinhardt, Annekathrin;
    • Sievers, Philipp;
    • Casalini, M. Belén;
    • Ebrahimi, Azadeh
    Publication type:
    Article
    32

    Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions.

    Published in:
    Acta Neuropathologica, 2019, v. 138, n. 5, p. 827, doi. 10.1007/s00401-019-02039-3
    By:
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Casalini, Belén;
    • Meyer, Jochen;
    • Wefers, Annika K.;
    • Sievers, Philipp;
    • Korshunov, Andrey;
    • Koelsche, Christian;
    • Reuss, David E.;
    • Reinhardt, Annekathrin;
    • Ebrahimi, Azadeh;
    • Fernández-Klett, Francisco;
    • Kessler, Tobias;
    • Sturm, Dominik;
    • Ecker, Jonas;
    • Milde, Till;
    • Herold-Mende, Christel;
    • Witt, Olaf;
    • Pfister, Stefan M.;
    • Wick, Wolfgang
    Publication type:
    Article
    33

    Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1.

    Published in:
    Acta Neuropathologica, 2019, v. 138, n. 3, p. 497, doi. 10.1007/s00401-019-02038-4
    By:
    • Sievers, Philipp;
    • Appay, Romain;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Reuss, David E.;
    • Wefers, Annika K.;
    • Reinhardt, Annekathrin;
    • Coras, Roland;
    • Ruf, Viktoria C.;
    • Schmid, Simone;
    • de Stricker, Karin;
    • Boldt, Henning B.;
    • Kristensen, Bjarne Winther;
    • Petersen, Jeanette Krogh;
    • Ulhøi, Benedicte P.;
    • Gardberg, Maria;
    • Aronica, Eleonora;
    • Hasselblatt, Martin;
    • Brück, Wolfgang;
    • Bielle, Franck
    Publication type:
    Article
    34

    Molecular progression of SHH-activated medulloblastomas.

    Published in:
    2019
    By:
    • Korshunov, Andrey;
    • Okonechnikov, Konstantin;
    • Sahm, Felix;
    • Ryzhova, Marina;
    • Stichel, Damian;
    • Sievers, Philipp;
    • Meyer, Jochen;
    • Schrimpf, Daniel;
    • Zheludkova, Olga;
    • Golanov, Andrey;
    • Lichter, Peter;
    • Jones, David T. W.;
    • Pfister, Stefan M.;
    • von Deimling, Andreas;
    • Kool, Marcel
    Publication type:
    Letter
    35

    Mutational patterns and regulatory networks in epigenetic subgroups of meningioma.

    Published in:
    Acta Neuropathologica, 2019, v. 138, n. 2, p. 295, doi. 10.1007/s00401-019-02008-w
    By:
    • Paramasivam, Nagarajan;
    • Hübschmann, Daniel;
    • Toprak, Umut H;
    • Ishaque, Naveed;
    • Neidert, Marian;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Reuss, David;
    • Sievers, Philipp;
    • Reinhardt, Annekathrin;
    • Wefers, Annika K.;
    • Jones, David T. W.;
    • Gu, Zuguang;
    • Werner, Johannes;
    • Uhrig, Sebastian;
    • Wirsching, Hans-Georg;
    • Schick, Matthias;
    • Bewerunge-Hudler, Melanie;
    • Beck, Katja;
    • Brehmer, Stephanie
    Publication type:
    Article
    36

    Desmoplastic/nodular medulloblastomas (DNMB) and medulloblastomas with extensive nodularity (MBEN) disclose similar epigenetic signatures but different transcriptional profiles.

    Published in:
    Acta Neuropathologica, 2019, v. 137, n. 6, p. 1003, doi. 10.1007/s00401-019-01981-6
    By:
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Casalini, Belen;
    • Sievers, Philipp;
    • Meyer, Jochen;
    • Sahm, Felix;
    • von Deimling, Andreas;
    • Korshunov, Andrey;
    • Jones, David T. W.;
    • Okonechnikov, Konstantin;
    • Kool, Marcel;
    • Pfister, Stefan M.;
    • Lichter, Peter;
    • Ryzhova, Marina;
    • Zheludkova, Olga;
    • Golanov, Andrey
    Publication type:
    Article
    37

    Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA.

    Published in:
    Acta Neuropathologica, 2019, v. 137, n. 5, p. 837, doi. 10.1007/s00401-019-01969-2
    By:
    • Hou, Yanghao;
    • Pinheiro, Jorge;
    • Sahm, Felix;
    • Reuss, David E.;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Casalini, Belén;
    • Koelsche, Christian;
    • Sievers, Philipp;
    • Wefers, Annika K.;
    • Reinhardt, Annekathrin;
    • Ebrahimi, Azadeh;
    • Fernández-Klett, Francisco;
    • Pusch, Stefan;
    • Meier, Jochen;
    • Schweizer, Leonille;
    • Paulus, Werner;
    • Prinz, Marco;
    • Hartmann, Christian;
    • Plate, Karl H.
    Publication type:
    Article
    38

    Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p.

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 6, p. 975, doi. 10.1007/s00401-018-1924-x
    By:
    • Sievers, Philipp;
    • Stichel, Damian;
    • Hielscher, Thomas;
    • Schrimpf, Daniel;
    • Reinhardt, Annekathrin;
    • Wefers, Annika K.;
    • Reuss, David;
    • Jones, David T. W.;
    • Bewerunge-Hudler, Melanie;
    • Hartmann, Christian;
    • Baumgarten, Peter;
    • Wirsching, Hans-Georg;
    • Winther-Kristensen, Bjarne;
    • Brokinkel, Benjamin;
    • Ketter, Ralf;
    • Idoate Gastearena, Miguel Angel;
    • Lamszus, Katrin;
    • Seiz-Rosenhagen, Marcel;
    • Mawrin, Christian;
    • Harter, Patrick N.
    Publication type:
    Article
    39

    Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the reclassification of IDHwt astrocytoma to glioblastoma.

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 5, p. 793, doi. 10.1007/s00401-018-1905-0
    By:
    • Stichel, Damian;
    • Ebrahimi, Azadeh;
    • Reuss, David;
    • Schrimpf, Daniel;
    • Ono, Takahiro;
    • Shirahata, Mitsuaki;
    • Reifenberger, Guido;
    • Weller, Michael;
    • Hänggi, Daniel;
    • Wick, Wolfgang;
    • Herold-Mende, Christel;
    • Westphal, Manfred;
    • Brandner, Sebastian;
    • Pfister, Stefan M.;
    • Capper, David;
    • Sahm, Felix;
    • von Deimling, Andreas
    Publication type:
    Article
    40

    Correction to: DNA methylation-based reclassification of olfactory neuroblastoma.

    Published in:
    2018
    By:
    • Capper, David;
    • Engel, Nils W.;
    • Stichel, Damian;
    • Lechner, Matt;
    • Glöss, Stefanie;
    • Schmid, Simone;
    • Kölsche, Christian;
    • Schrimpf, Daniel;
    • Niesen, Judith;
    • Wefers, Annika K.;
    • Jones, David T. W.;
    • Sill, Martin;
    • Weigert, Oliver;
    • Ligon, Keith L.;
    • Olar, Adriana;
    • Koch, Arend;
    • Forster, Martin;
    • Moran, Sebastian;
    • Tirado, Oscar M.;
    • Sáinz-Jaspeado, Miguel
    Publication type:
    Correction Notice
    41

    FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma.

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 2, p. 293, doi. 10.1007/s00401-018-1882-3
    By:
    • Sievers, Philipp;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Sahm, Felix;
    • Koelsche, Christian;
    • Reuss, David E.;
    • Wefers, Annika K.;
    • Reinhardt, Annekathrin;
    • Huang, Kristin;
    • Ebrahimi, Azadeh;
    • Hou, Yanghao;
    • Pajtler, Kristian W.;
    • Pfister, Stefan M.;
    • Hasselblatt, Martin;
    • Stummer, Walter;
    • Schick, Uta;
    • Hartmann, Christian;
    • Hagel, Christian;
    • Staszewski, Ori;
    • Reifenberger, Guido
    Publication type:
    Article
    42

    Molecular characterization of medulloblastomas with extensive nodularity (MBEN).

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 2, p. 303, doi. 10.1007/s00401-018-1840-0
    By:
    • Korshunov, Andrey;
    • Sahm, Felix;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Ryzhova, Marina;
    • Zheludkova, Olga;
    • Golanov, Andrey;
    • Lichter, Peter;
    • Jones, David T. W.;
    • von Deimling, Andreas;
    • Pfister, Stefan M.;
    • Kool, Marcel
    Publication type:
    Article
    43

    DNA methylation-based reclassification of olfactory neuroblastoma.

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 2, p. 255, doi. 10.1007/s00401-018-1854-7
    By:
    • Capper, David;
    • Engel, Nils W.;
    • Stichel, Damian;
    • Lechner, Matt;
    • Glöss, Stefanie;
    • Schmid, Simone;
    • Koelsche, Christian;
    • Schrimpf, Daniel;
    • Niesen, Judith;
    • Wefers, Annika K.;
    • Jones, David T. W.;
    • Sill, Martin;
    • Weigert, Oliver;
    • Ligon, Keith L.;
    • Olar, Adriana;
    • Koch, Arend;
    • Forster, Martin;
    • Moran, Sebastian;
    • Tirado, Oscar M.;
    • Sáinz-Jaspeado, Miguel
    Publication type:
    Article
    44

    Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience.

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 2, p. 181, doi. 10.1007/s00401-018-1879-y
    By:
    • Capper, David;
    • Stichel, Damian;
    • Sahm, Felix;
    • Jones, David T. W.;
    • Schrimpf, Daniel;
    • Sill, Martin;
    • Schmid, Simone;
    • Hovestadt, Volker;
    • Reuss, David E.;
    • Koelsche, Christian;
    • Reinhardt, Annekathrin;
    • Wefers, Annika K.;
    • Huang, Kristin;
    • Sievers, Philipp;
    • Ebrahimi, Azadeh;
    • Schöler, Anne;
    • Teichmann, Daniel;
    • Koch, Arend;
    • Hänggi, Daniel;
    • Unterberg, Andreas
    Publication type:
    Article
    45

    Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations.

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 2, p. 273, doi. 10.1007/s00401-018-1837-8
    By:
    • Reinhardt, Annekathrin;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Sahm, Felix;
    • Korshunov, Andrey;
    • Reuss, David E.;
    • Koelsche, Christian;
    • Huang, Kristin;
    • Wefers, Annika K.;
    • Hovestadt, Volker;
    • Sill, Martin;
    • Gramatzki, Dorothee;
    • Felsberg, Joerg;
    • Reifenberger, Guido;
    • Koch, Arend;
    • Thomale, Ulrich-W.;
    • Becker, Albert;
    • Hans, Volkmar H.;
    • Prinz, Marco;
    • Staszewski, Ori
    Publication type:
    Article
    46

    Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations.

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 2, p. 327, doi. 10.1007/s00401-018-1871-6
    By:
    • Koelsche, Christian;
    • Mynarek, Martin;
    • Schrimpf, Daniel;
    • Bertero, Luca;
    • Serrano, Jonathan;
    • Sahm, Felix;
    • Reuss, David E.;
    • Hou, Yanghao;
    • Baumhoer, Daniel;
    • Vokuhl, Christian;
    • Flucke, Uta;
    • Petersen, Iver;
    • Brück, Wolfgang;
    • Rutkowski, Stefan;
    • Zambrano, Sandro Casavilca;
    • Garcia Leon, Juan Luis;
    • Diaz Coronado, Rosdali Yesenia;
    • Gessler, Manfred;
    • Tirado, Oscar M.;
    • Mora, Jaume
    Publication type:
    Article
    47

    Novel, improved grading system(s) for IDH-mutant astrocytic gliomas.

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 1, p. 153, doi. 10.1007/s00401-018-1849-4
    By:
    • Shirahata, Mitsuaki;
    • Ono, Takahiro;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Reuss, David E.;
    • Sahm, Felix;
    • Koelsche, Christian;
    • Wefers, Annika;
    • Reinhardt, Annekathrin;
    • Huang, Kristin;
    • Sievers, Philipp;
    • Shimizu, Hiroaki;
    • Nanjo, Hiroshi;
    • Kobayashi, Yusuke;
    • Miyake, Yohei;
    • Suzuki, Tomonari;
    • Adachi, Jun-ichi;
    • Mishima, Kazuhiko;
    • Sasaki, Atsushi;
    • Nishikawa, Ryo
    Publication type:
    Article
    48

    H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers.

    Published in:
    Acta Neuropathologica, 2017, v. 134, n. 3, p. 507, doi. 10.1007/s00401-017-1710-1
    By:
    • Korshunov, Andrey;
    • Schrimpf, Daniel;
    • Ryzhova, Marina;
    • Sturm, Dominik;
    • Chavez, Lukas;
    • Hovestadt, Volker;
    • Sharma, Tanvi;
    • Habel, Antje;
    • Burford, Anna;
    • Jones, Chris;
    • Zheludkova, Olga;
    • Kumirova, Ella;
    • Kramm, Christof;
    • Golanov, Andrey;
    • Capper, David;
    • Deimling, Andreas;
    • Pfister, Stefan;
    • Jones, David
    Publication type:
    Article
    49
    50

    Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo.

    Published in:
    Acta Neuropathologica, 2017, v. 133, n. 4, p. 629, doi. 10.1007/s00401-017-1677-y
    By:
    • Pusch, Stefan;
    • Krausert, Sonja;
    • Fischer, Viktoria;
    • Balss, Jörg;
    • Ott, Martina;
    • Schrimpf, Daniel;
    • Capper, David;
    • Sahm, Felix;
    • Eisel, Jessica;
    • Beck, Ann-Christin;
    • Jugold, Manfred;
    • Eichwald, Viktoria;
    • Kaulfuss, Stefan;
    • Panknin, Olaf;
    • Rehwinkel, Hartmut;
    • Zimmermann, Katja;
    • Hillig, Roman;
    • Guenther, Judith;
    • Toschi, Luisella;
    • Neuhaus, Roland
    Publication type:
    Article