Works matching AU Schrimpf, Daniel

Results: 82

Prognostic impact of genetic alterations and methylation classes in meningioma.

Published in:

Brain Pathology, 2022, v. 32, n. 2, p. 1, doi. 10.1111/bpa.12970

By:

Berghoff, Anna S.;
Hielscher, Thomas;
Ricken, Gerda;
Furtner, Julia;
Schrimpf, Daniel;
Widhalm, Georg;
Rajky, Ursula;
Marosi, Christine;
Hainfellner, Johannes A.;
von Deimling, Andreas;
Sahm, Felix;
Preusser, Matthias

Publication type:

Article

Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis.

Published in:

Brain Pathology, 2018, v. 28, n. 5, p. 656, doi. 10.1111/bpa.12566

By:

Korshunov, Andrey;
Chavez, Lukas;
Sharma, Tanvi;
Ryzhova, Marina;
Schrimpf, Daniel;
Stichel, Damian;
Capper, David;
Sturm, Dominik;
Kool, Marcel;
Habel, Antje;
Kleinschmidt‐DeMasters, Bette K.;
Rosenblum, Marc;
Absalyamova, Oksana;
Golanov, Andrey;
Lichter, Peter;
Pfister, Stefan M.;
Jones, David T.W.;
Perry, Arie;
von Deimling, Andreas

Publication type:

Article

Melanotic Tumors of the Nervous System are Characterized by Distinct Mutational, Chromosomal and Epigenomic Profiles.

Published in:

Brain Pathology, 2015, v. 25, n. 2, p. 202, doi. 10.1111/bpa.12228

By:

Koelsche, Christian;
Hovestadt, Volker;
Jones, David T. W.;
Capper, David;
Sturm, Dominik;
Sahm, Felix;
Schrimpf, Daniel;
Adeberg, Sebastian;
Böhmer, Katja;
Hagenlocher, Christian;
Mechtersheimer, Gunhild;
Kohlhof, Patricia;
Mühleisen, Helmut;
Beschorner, Rudi;
Hartmann, Christian;
Braczynski, Anne Kristin;
Mittelbronn, Michel;
Buslei, Rolf;
Becker, Albert;
Grote, Alexander

Publication type:

Article

Adaptive randomization procedures for the web-based randomization system RANDI2.

Published in:

International Journal of Clinical Pharmacology & Therapeutics, 2012, v. 50, n. 1, p. 85, doi. 10.5414/CPP50085

By:

Schrimpf, Daniel;
Pilz, Lothar R.

Publication type:

Article

DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnostics.

Published in:

Journal of Cancer Research & Clinical Oncology, 2020, v. 146, n. 1, p. 97, doi. 10.1007/s00432-019-03093-w

By:

Kommoss, Felix K. F.;
Stichel, Damian;
Schrimpf, Daniel;
Kriegsmann, Mark;
Tessier-Cloutier, Basile;
Talhouk, Aline;
McAlpine, Jessica N.;
Chang, Kenneth T. E.;
Sturm, Dominik;
Pfister, Stefan M.;
Romero-Pérez, Laura;
Kirchner, Thomas;
Grünewald, Thomas G. P.;
Buslei, Rolf;
Sinn, Hans-Peter;
Mechtersheimer, Gunhild;
Schirmacher, Peter;
Schmidt, Dietmar;
Lehr, Hans-Anton;
Sahm, Felix

Publication type:

Article

Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01118-5

By:

Korshunov, Andrey;
Okonechnikov, Konstantin;
Schmitt-Hoffner, Felix;
Ryzhova, Marina;
Sahm, Felix;
Stichel, Damian;
Schrimpf, Daniel;
Reuss, David E.;
Sievers, Philipp;
Suwala, Abigail Kora;
Kumirova, Ella;
Zheludkova, Olga;
Golanov, Andrey;
Jones, David T. W.;
Pfister, Stefan M.;
Kool, Marcel;
von Deimling, Andreas

Publication type:

Article

Anaplastic ganglioglioma—A diagnosis comprising several distinct tumour types.

Published in:

Neuropathology & Applied Neurobiology, 2022, v. 48, n. 7, p. 1, doi. 10.1111/nan.12847

By:

Reinhardt, Annekathrin;
Pfister, Kristin;
Schrimpf, Daniel;
Stichel, Damian;
Sahm, Felix;
Reuss, David E.;
Capper, David;
Wefers, Annika K.;
Ebrahimi, Azadeh;
Sill, Martin;
Felsberg, Joerg;
Reifenberger, Guido;
Becker, Albert;
Prinz, Marco;
Staszewski, Ori;
Hartmann, Christian;
Schittenhelm, Jens;
Gramatzki, Dorothee;
Weller, Michael;
Olar, Adriana

Publication type:

Article

Accurate calling of KIAA1549‐BRAF fusions from DNA of human brain tumours using methylation array‐based copy number and gene panel sequencing data.

Published in:

Neuropathology & Applied Neurobiology, 2021, v. 47, n. 3, p. 406, doi. 10.1111/nan.12683

By:

Stichel, Damian;
Schrimpf, Daniel;
Sievers, Philipp;
Reinhardt, Annekathrin;
Suwala, Abigail K.;
Sill, Martin;
Reuss, David E.;
Korshunov, Andrey;
Casalini, Belén M.;
Sommerkamp, Alexander C.;
Ecker, Jonas;
Selt, Florian;
Sturm, Dominik;
Gnekow, Astrid;
Koch, Arend;
Simon, Michèle;
Hernáiz Driever, Pablo;
Schüller, Ulrich;
Capper, David;
Tilburg, Cornelis M.

Publication type:

Article

Design of clinical studies: Adaptive randomization and progression-free survival (PFS) as an endpoint in clinical studies of advanced non-small cell lung cancer (NSCLC).

Published in:

International Journal of Clinical Pharmacology & Therapeutics, 2013, v. 51, n. 1, p. 84, doi. 10.5414/CPP51084

By:

Schrimpf, Daniel;
Manegold, Christian;
Pilz, Lothar R.

Publication type:

Article

SHH desmoplastic/nodular medulloblastoma and Gorlin syndrome in the setting of Down syndrome: case report, molecular profiling, and review of the literature.

Published in:

Child's Nervous System, 2016, v. 32, n. 12, p. 2439, doi. 10.1007/s00381-016-3185-0

By:

Mangum, Ross;
Varga, Elizabeth;
Boué, Daniel;
Capper, David;
Benesch, Martin;
Leonard, Jeffrey;
Osorio, Diana;
Pierson, Christopher;
Zumberge, Nicholas;
Sahm, Felix;
Schrimpf, Daniel;
Pfister, Stefan;
Finlay, Jonathan

Publication type:

Article

TERT Promoter Mutations and Risk of Recurrence in Meningioma.

Published in:

2016

By:

Sahm, Felix;
Schrimpf, Daniel;
Olar, Adriana;
Koelsche, Christian;
Reuss, David;
Bissel, Juliane;
Kratz, Annekathrin;
Capper, David;
Schefzyk, Sebastian;
Hielscher, Thomas;
Qianghu Wang;
Sulman, Erik P.;
Adeberg, Sebastian;
Koch, Arend;
Okuducu, Ali Fuat;
Brehmer, Stefanie;
Schittenhelm, Jens;
Becker, Albert;
Brokinkel, Benjamin;
Schmidt, Melissa

Publication type:

journal article

Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling.

Published in:

Acta Neuropathologica Communications, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40478-024-01921-w

By:

Okonechnikov, Konstantin;
Ghasemi, David R.;
Schrimpf, Daniel;
Tonn, Svenja;
Mynarek, Martin;
Koster, Jan;
Milde, Till;
Zheng, Tuyu;
Sievers, Philipp;
Sahm, Felix;
Jones, David T.W.;
von Deimling, Andreas;
Pfister, Stefan M.;
Kool, Marcel;
Pajtler, Kristian W.;
Korshunov, Andrey

Publication type:

Article

Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling.

Published in:

Acta Neuropathologica Communications, 2025, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01921-w

By:

Okonechnikov, Konstantin;
Ghasemi, David R.;
Schrimpf, Daniel;
Tonn, Svenja;
Mynarek, Martin;
Koster, Jan;
Milde, Till;
Zheng, Tuyu;
Sievers, Philipp;
Sahm, Felix;
Jones, David T.W.;
von Deimling, Andreas;
Pfister, Stefan M.;
Kool, Marcel;
Pajtler, Kristian W.;
Korshunov, Andrey

Publication type:

Article

Genomic characterization of DICER1-associated neoplasms uncovers molecular classes.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37092-w

By:

Kommoss, Felix K. F.;
Chong, Anne-Sophie;
Chong, Anne-Laure;
Pfaff, Elke;
Jones, David T. W.;
Hiemcke-Jiwa, Laura S.;
Kester, Lennart A.;
Flucke, Uta;
Gessler, Manfred;
Schrimpf, Daniel;
Sahm, Felix;
Clarke, Blaise A.;
Stewart, Colin J. R.;
Wang, Yemin;
Gilks, C. Blake;
Kommoss, Friedrich;
Huntsman, David G.;
Schüller, Ulrich;
Koelsche, Christian;
Glenn McCluggage, W.

Publication type:

Article

Integrated analysis of dynamic FET PET/CT parameters, histology, and methylation profiling of 44 gliomas.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2018, v. 45, n. 9, p. 1573, doi. 10.1007/s00259-018-4009-0

By:

Röhrich, Manuel;
Huang, Kristin;
Schrimpf, Daniel;
Albert, Nathalie L.;
Hielscher, Thomas;
von Deimling, Andreas;
Schüller, Ulrich;
Dimitrakopoulou-Strauss, Antonia;
Haberkorn, Uwe

Publication type:

Article

Sarcoma classification by DNA methylation profiling.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20603-4

By:

Koelsche, Christian;
Schrimpf, Daniel;
Stichel, Damian;
Sill, Martin;
Sahm, Felix;
Reuss, David E.;
Blattner, Mirjam;
Worst, Barbara;
Heilig, Christoph E.;
Beck, Katja;
Horak, Peter;
Kreutzfeldt, Simon;
Paff, Elke;
Stark, Sebastian;
Johann, Pascal;
Selt, Florian;
Ecker, Jonas;
Sturm, Dominik;
Pajtler, Kristian W.;
Reinhardt, Annekathrin

Publication type:

Article

Somatic Mutations of DICER1 and KMT2D are Frequent in Intraocular Medulloepitheliomas.

Published in:

Genes, Chromosomes & Cancer, 2016, v. 55, n. 5, p. 418, doi. 10.1002/gcc.22344

By:

Sahm, Felix;
Jakobiec, Frederick A.;
Meyer, Jochen;
Schrimpf, Daniel;
Eberhart, Charles G.;
Hovestadt, Volker;
Capper, David;
Lambo, Sander;
Ryzhova, Marina;
Schüller, Ulrich;
Zheludkova, Olga;
Kumirova, Ella;
Lichter, Peter;
von Deimling, Andreas;
Jones, David T. W.;
Pfister, Stefan M.;
Kool, Marcel;
Korshunov, Andrey

Publication type:

Article

Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature.

Published in:

NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00372-1

By:

Sievers, Philipp;
Sill, Martin;
Schrimpf, Daniel;
Abdullaev, Zied;
Donson, Andrew M.;
Lake, Jessica A.;
Friedel, Dennis;
Scheie, David;
Tynninen, Olli;
Rauramaa, Tuomas;
Vepsäläinen, Kaisa L.;
Samuel, David;
Chapman, Rebecca;
Grundy, Richard G.;
Pajtler, Kristian W.;
Tauziède-Espariat, Arnault;
Métais, Alice;
Varlet, Pascale;
Snuderl, Matija;
Jacques, Thomas S.

Publication type:

Article

DNA methylation‐based profiling of bone and soft tissue tumours: a validation study of the 'DKFZ Sarcoma Classifier'.

Published in:

Journal of Pathology: Clinical Research, 2021, v. 7, n. 4, p. 350, doi. 10.1002/cjp2.215

By:

Lyskjær, Iben;
De Noon, Solange;
Tirabosco, Roberto;
Rocha, Ana Maia;
Lindsay, Daniel;
Amary, Fernanda;
Ye, Hongtao;
Schrimpf, Daniel;
Stichel, Damian;
Sill, Martin;
Koelsche, Christian;
Pillay, Nischalan;
Von Deimling, Andreas;
Beck, Stephan;
Flanagan, Adrienne M

Publication type:

Article

Comparison of transcriptome profiles between medulloblastoma primary and recurrent tumors uncovers novel variance effects in relapses.

Published in:

Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01504-1

By:

Okonechnikov, Konstantin;
Federico, Aniello;
Schrimpf, Daniel;
Sievers, Philipp;
Sahm, Felix;
Koster, Jan;
Jones, David T. W.;
von Deimling, Andreas;
Pfister, Stefan M.;
Kool, Marcel;
Korshunov, Andrey

Publication type:

Article

Constitutional variants in PTEN: a frequent finding in patients with papillary tumors of the pineal region subtype B (PTPR-B) associated with isolated loss of chromosome 10.

Published in:

2025

By:

Hirsch, Steffen;
Rahmanzade, Ramin;
Grund, Kerstin;
Sutter, Christian;
Schramm, Kathrin;
Selt, Florian;
Ecker, Jonas;
Jones, Barbara C.;
Schrimpf, Daniel;
Demmert, Martin;
Guerreiro Stücklin, Ana S.;
Hernaiz Driever, Pablo;
Mezger, Markus;
Brecht, Ines;
Adib, Sasan D.;
Brummel, Bastian;
Sturm, Dominik;
Dikow, Nicola;
Hempel, Maja;
Milde, Till

Publication type:

Letter

Identification of a putative molecular subtype of adult-type diffuse astrocytoma with recurrent MAPK pathway alterations.

Published in:

Acta Neuropathologica, 2024, v. 148, n. 1, p. 1, doi. 10.1007/s00401-024-02766-2

By:

Sievers, Philipp;
Bielle, Franck;
Göbel, Kirsten;
Schrimpf, Daniel;
Nichelli, Lucia;
Mathon, Bertrand;
Appay, Romain;
Boldt, Henning B.;
Dohmen, Hildegard;
Selignow, Carmen;
Acker, Till;
Vicha, Ales;
Martinetto, Horacio;
Schweizer, Leonille;
Schüller, Ulrich;
Brandner, Sebastian;
Wesseling, Pieter;
Schmid, Simone;
Capper, David;
Abdullaev, Zied

Publication type:

Article

Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations.

Published in:

Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-024-02746-6

By:

Okonechnikov, Konstantin;
Schrimpf, Daniel;
Koster, Jan;
Sievers, Philipp;
Milde, Till;
Sahm, Felix;
Jones, David T. W.;
von Deimling, Andreas;
Pfister, Stefan M.;
Kool, Marcel;
Korshunov, Andrey

Publication type:

Article

Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics.

Published in:

Acta Neuropathologica, 2023, v. 146, n. 6, p. 853, doi. 10.1007/s00401-023-02638-1

By:

Rahmanzade, Ramin;
Pfaff, Elke;
Banan, Rouzbeh;
Sievers, Philipp;
Suwala, Abigail K.;
Hinz, Felix;
Bogumil, Henri;
Cherkezov, Asan;
Kaan, Aras Fuat;
Schrimpf, Daniel;
Friedel, Dennis;
Göbel, Kirsten;
Keller, Felix;
Saenz-Sardà, Xavier;
Lossos, Alexander;
Sill, Martin;
Witt, Olaf;
Sakowitz, Oliver W.;
Korshunov, Andrey;
Reuss, David E.

Publication type:

Article

Transcriptome analysis stratifies second-generation non-WNT/non-SHH medulloblastoma subgroups into clinically tractable subtypes.

Published in:

Acta Neuropathologica, 2023, v. 145, n. 6, p. 829, doi. 10.1007/s00401-023-02575-z

By:

Korshunov, Andrey;
Okonechnikov, Konstantin;
Schrimpf, Daniel;
Tonn, Svenja;
Mynarek, Martin;
Koster, Jan;
Sievers, Philipp;
Milde, Till;
Sahm, Felix;
Jones, David T. W.;
von Deimling, Andreas;
Pfister, Stefan M.;
Kool, Marcel

Publication type:

Article

Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions.

Published in:

Acta Neuropathologica, 2023, v. 145, n. 5, p. 667, doi. 10.1007/s00401-023-02558-0

By:

Bogumil, Henri;
Sill, Martin;
Schrimpf, Daniel;
Ismer, Britta;
Blume, Christina;
Rahmanzade, Ramin;
Hinz, Felix;
Cherkezov, Asan;
Banan, Rouzbeh;
Friedel, Dennis;
Reuss, David E.;
Selt, Florian;
Ecker, Jonas;
Milde, Till;
Pajtler, Kristian W.;
Schittenhelm, Jens;
Hench, Jürgen;
Frank, Stephan;
Boldt, Henning B.;
Kristensen, Bjarne Winther

Publication type:

Article

Epigenetic profiling reveals a subset of pediatric-type glioneuronal tumors characterized by oncogenic gene fusions involving several targetable kinases.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 5, p. 1049, doi. 10.1007/s00401-022-02492-7

By:

Sievers, Philipp;
Sill, Martin;
Schrimpf, Daniel;
Friedel, Dennis;
Sturm, Dominik;
Gardberg, Maria;
Kurian, Kathreena M.;
Krskova, Lenka;
Vicha, Ales;
Schaller, Tina;
Hagel, Christian;
Abdullaev, Zied;
Aldape, Kenneth;
Jacques, Thomas S.;
Korshunov, Andrey;
Wick, Wolfgang;
Pfister, Stefan M.;
von Deimling, Andreas;
Jones, David T. W.;
Sahm, Felix

Publication type:

Article

Gene expression profiling of Group 3 medulloblastomas defines a clinically tractable stratification based on KIRREL2 expression.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 2, p. 339, doi. 10.1007/s00401-022-02460-1

By:

Korshunov, Andrey;
Okonechnikov, Konstantin;
Stichel, Damian;
Schrimpf, Daniel;
Delaidelli, Alberto;
Tonn, Svenja;
Mynarek, Martin;
Sievers, Philipp;
Sahm, Felix;
Jones, David T. W.;
von Deimling, Andreas;
Pfister, Stefan M.;
Kool, Marcel

Publication type:

Article

DNA-methylome-assisted classification of patients with poor prognostic subventricular zone associated IDH-wildtype glioblastoma.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 1, p. 129, doi. 10.1007/s00401-022-02443-2

By:

Adeberg, Sebastian;
Knoll, Maximilian;
Koelsche, Christian;
Bernhardt, Denise;
Schrimpf, Daniel;
Sahm, Felix;
König, Laila;
Harrabi, Semi Ben;
Hörner-Rieber, Juliane;
Verma, Vivek;
Bewerunge-Hudler, Melanie;
Unterberg, Andreas;
Sturm, Dominik;
Jungk, Christine;
Herold-Mende, Christel;
Wick, Wolfgang;
von Deimling, Andreas;
Debus, Juergen;
Rieken, Stefan;
Abdollahi, Amir

Publication type:

Article

Rapid-CNS<sup>2</sup>: rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study.

Published in:

Acta Neuropathologica, 2022, v. 143, n. 5, p. 609, doi. 10.1007/s00401-022-02415-6

By:

Patel, Areeba;
Dogan, Helin;
Payne, Alexander;
Krause, Elena;
Sievers, Philipp;
Schoebe, Natalie;
Schrimpf, Daniel;
Blume, Christina;
Stichel, Damian;
Holmes, Nadine;
Euskirchen, Philipp;
Hench, Jürgen;
Frank, Stephan;
Rosenstiel-Goidts, Violaine;
Ratliff, Miriam;
Etminan, Nima;
Unterberg, Andreas;
Dieterich, Christoph;
Herold-Mende, Christel;
Pfister, Stefan M.

Publication type:

Article

Oligosarcomas, IDH-mutant are distinct and aggressive.

Published in:

Acta Neuropathologica, 2022, v. 143, n. 2, p. 263, doi. 10.1007/s00401-021-02395-z

By:

Suwala, Abigail K.;
Felix, Marius;
Friedel, Dennis;
Stichel, Damian;
Schrimpf, Daniel;
Hinz, Felix;
Hewer, Ekkehard;
Schweizer, Leonille;
Dohmen, Hildegard;
Pohl, Ute;
Staszewski, Ori;
Korshunov, Andrey;
Stein, Marco;
Wongsurawat, Thidathip;
Cheunsuacchon, Pornsuk;
Sathornsumetee, Sith;
Koelsche, Christian;
Turner, Clinton;
Le Rhun, Emilie;
Mühlebner, Angelika

Publication type:

Article

GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.

Published in:

Acta Neuropathologica, 2021, v. 142, n. 6, p. 1065, doi. 10.1007/s00401-021-02369-1

By:

Sievers, Philipp;
Stichel, Damian;
Sill, Martin;
Schrimpf, Daniel;
Sturm, Dominik;
Selt, Florian;
Ecker, Jonas;
Kazdal, Daniel;
Miele, Evelina;
Kranendonk, Mariëtte E. G.;
Tops, Bastiaan B. J.;
Kohlhof-Meinecke, Patricia;
Beschorner, Rudi;
Kramm, Christof M.;
Hasselblatt, Martin;
Reifenberger, Guido;
Capper, David;
Wesseling, Pieter;
Stenzinger, Albrecht;
Milde, Till

Publication type:

Article

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors.

Published in:

Acta Neuropathologica, 2021, v. 142, n. 5, p. 827, doi. 10.1007/s00401-021-02356-6

By:

Sievers, Philipp;
Henneken, Sophie C.;
Blume, Christina;
Sill, Martin;
Schrimpf, Daniel;
Stichel, Damian;
Okonechnikov, Konstantin;
Reuss, David E.;
Benzel, Julia;
Maaß, Kendra K.;
Kool, Marcel;
Sturm, Dominik;
Zheng, Tuyu;
Ghasemi, David R.;
Kohlhof-Meinecke, Patricia;
Cruz, Ofelia;
Suñol, Mariona;
Lavarino, Cinzia;
Ruf, Viktoria;
Boldt, Henning B.

Publication type:

Article

Molecular profiling of pediatric meningiomas shows tumor characteristics distinct from adult meningiomas.

Published in:

Acta Neuropathologica, 2021, v. 142, n. 5, p. 873, doi. 10.1007/s00401-021-02351-x

By:

Kirches, Elmar;
Sahm, Felix;
Korshunov, Andrey;
Bluecher, Christina;
Waldt, Natalie;
Kropf, Siegfried;
Schrimpf, Daniel;
Sievers, Philipp;
Stichel, Damian;
Schüller, Ulrich;
Schittenhelm, Jens;
Riemenschneider, Markus J.;
Karajannis, Matthias A.;
Perry, Arie;
Pietsch, Torsten;
Boekhoff, Svenja;
Capper, David;
Beck, Katja;
Paramasivam, Nagarajan;
Schlesner, Matthias

Publication type:

Article

Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1.

Published in:

Acta Neuropathologica, 2021, v. 142, n. 1, p. 179, doi. 10.1007/s00401-021-02302-6

By:

Suwala, Abigail K.;
Stichel, Damian;
Schrimpf, Daniel;
Maas, Sybren L. N.;
Sill, Martin;
Dohmen, Hildegard;
Banan, Rouzbeh;
Reinhardt, Annekathrin;
Sievers, Philipp;
Hinz, Felix;
Blattner-Johnson, Mirjam;
Hartmann, Christian;
Schweizer, Leonille;
Boldt, Henning B.;
Kristensen, Bjarne Winther;
Schittenhelm, Jens;
Wood, Matthew D.;
Chotard, Guillaume;
Bjergvig, Rolf;
Das, Anirban

Publication type:

Article

Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis.

Published in:

Acta Neuropathologica, 2021, v. 141, n. 1, p. 85, doi. 10.1007/s00401-020-02243-6

By:

Suwala, Abigail K.;
Stichel, Damian;
Schrimpf, Daniel;
Kloor, Matthias;
Wefers, Annika K.;
Reinhardt, Annekathrin;
Maas, Sybren L. N.;
Kratz, Christian P.;
Schweizer, Leonille;
Hasselblatt, Martin;
Snuderl, Matija;
Abedalthagafi, Malak Sameer J.;
Abdullaev, Zied;
Monoranu, Camelia M.;
Bergmann, Markus;
Pekrun, Arnulf;
Freyschlag, Christian;
Aronica, Eleonora;
Kramm, Christof M.;
Hinz, Felix

Publication type:

Article

Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1.

Published in:

Acta Neuropathologica, 2021, v. 141, n. 2, p. 281, doi. 10.1007/s00401-020-02247-2

By:

Sievers, Philipp;
Sill, Martin;
Blume, Christina;
Tauziede-Espariat, Arnault;
Schrimpf, Daniel;
Stichel, Damian;
Reuss, David E.;
Dogan, Helin;
Hartmann, Christian;
Mawrin, Christian;
Hasselblatt, Martin;
Stummer, Walter;
Schick, Uta;
Hench, Jürgen;
Frank, Stephan;
Ketter, Ralf;
Schweizer, Leonille;
Schittenhelm, Jens;
Puget, Stéphanie;
Brandner, Sebastian

Publication type:

Article

Infratentorial IDH-mutant astrocytoma is a distinct subtype.

Published in:

Acta Neuropathologica, 2020, v. 140, n. 4, p. 569, doi. 10.1007/s00401-020-02194-y

By:

Banan, Rouzbeh;
Stichel, Damian;
Bleck, Anja;
Hong, Bujung;
Lehmann, Ulrich;
Suwala, Abigail;
Reinhardt, Annekathrin;
Schrimpf, Daniel;
Buslei, Rolf;
Stadelmann, Christine;
Ehlert, Karoline;
Prinz, Marco;
Acker, Till;
Schittenhelm, Jens;
Kaul, David;
Schweizer, Leonille;
Capper, David;
Harter, Patrick N.;
Etminan, Nima;
Jones, David T. W.

Publication type:

Article

CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas.

Published in:

Acta Neuropathologica, 2020, v. 140, n. 3, p. 409, doi. 10.1007/s00401-020-02188-w

By:

Sievers, Philipp;
Hielscher, Thomas;
Schrimpf, Daniel;
Stichel, Damian;
Reuss, David E.;
Berghoff, Anna S.;
Neidert, Marian C.;
Wirsching, Hans-Georg;
Mawrin, Christian;
Ketter, Ralf;
Paulus, Werner;
Reifenberger, Guido;
Lamszus, Katrin;
Westphal, Manfred;
Etminan, Nima;
Ratliff, Miriam;
Herold-Mende, Christel;
Pfister, Stefan M.;
Jones, David T. W.;
Weller, Michael

Publication type:

Article

Transcriptional profiling of medulloblastoma with extensive nodularity (MBEN) reveals two clinically relevant tumor subsets with VSNL1 as potent prognostic marker.

Published in:

Acta Neuropathologica, 2020, v. 139, n. 3, p. 583, doi. 10.1007/s00401-019-02102-z

By:

Korshunov, Andrey;
Okonechnikov, Konstantin;
Sahm, Felix;
Ryzhova, Marina;
Stichel, Damian;
Schrimpf, Daniel;
Ghasemi, David R.;
Pajtler, Kristian W.;
Antonelli, Manila;
Donofrio, Vittoria;
Mastronuzzi, Angela;
Rossi, Sabrina;
Camassei, Francesca Diomedi;
Buccoliero, Anna Maria;
Haberler, Christine;
Slavc, Irene;
Dahiya, Sonika;
Casalini, Belen;
Sievers, Philipp;
Meyer, Jochen

Publication type:

Article

Posterior fossa pilocytic astrocytomas with oligodendroglial features show frequent FGFR1 activation via fusion or mutation.

Published in:

2020

By:

Sievers, Philipp;
Schrimpf, Daniel;
Stichel, Damian;
Reuss, David E.;
Hasselblatt, Martin;
Hagel, Christian;
Staszewski, Ori;
Hench, Jürgen;
Frank, Stephan;
Brandner, Sebastian;
Korshunov, Andrey;
Wick, Wolfgang;
Pfister, Stefan M.;
Reifenberger, Guido;
von Deimling, Andreas;
Sahm, Felix;
Jones, David T. W.

Publication type:

Letter

YAP1-fusions in pediatric NF2-wildtype meningioma.

Published in:

2020

By:

Sievers, Philipp;
Chiang, Jason;
Schrimpf, Daniel;
Stichel, Damian;
Paramasivam, Nagarajan;
Sill, Martin;
Gayden, Tenzin;
Casalini, Belen;
Reuss, David E.;
Dalton, James;
Pajtler, Kristian W.;
Hänggi, Daniel;
Herold-Mende, Christel;
Rushing, Elisabeth;
Korshunov, Andrey;
Mawrin, Christian;
Weller, Michael;
Schlesner, Matthias;
Wick, Wolfgang;
Jabado, Nada

Publication type:

Letter

Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course.

Published in:

Acta Neuropathologica, 2020, v. 139, n. 1, p. 193, doi. 10.1007/s00401-019-02078-w

By:

Wefers, Annika K.;
Stichel, Damian;
Schrimpf, Daniel;
Coras, Roland;
Pages, Mélanie;
Tauziède-Espariat, Arnault;
Varlet, Pascale;
Schwarz, Daniel;
Söylemezoglu, Figen;
Pohl, Ute;
Pimentel, José;
Meyer, Jochen;
Hewer, Ekkehard;
Japp, Anna;
Joshi, Abhijit;
Reuss, David E.;
Reinhardt, Annekathrin;
Sievers, Philipp;
Casalini, M. Belén;
Ebrahimi, Azadeh

Publication type:

Article

Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions.

Published in:

Acta Neuropathologica, 2019, v. 138, n. 5, p. 827, doi. 10.1007/s00401-019-02039-3

By:

Stichel, Damian;
Schrimpf, Daniel;
Casalini, Belén;
Meyer, Jochen;
Wefers, Annika K.;
Sievers, Philipp;
Korshunov, Andrey;
Koelsche, Christian;
Reuss, David E.;
Reinhardt, Annekathrin;
Ebrahimi, Azadeh;
Fernández-Klett, Francisco;
Kessler, Tobias;
Sturm, Dominik;
Ecker, Jonas;
Milde, Till;
Herold-Mende, Christel;
Witt, Olaf;
Pfister, Stefan M.;
Wick, Wolfgang

Publication type:

Article

Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1.

Published in:

Acta Neuropathologica, 2019, v. 138, n. 3, p. 497, doi. 10.1007/s00401-019-02038-4

By:

Sievers, Philipp;
Appay, Romain;
Schrimpf, Daniel;
Stichel, Damian;
Reuss, David E.;
Wefers, Annika K.;
Reinhardt, Annekathrin;
Coras, Roland;
Ruf, Viktoria C.;
Schmid, Simone;
de Stricker, Karin;
Boldt, Henning B.;
Kristensen, Bjarne Winther;
Petersen, Jeanette Krogh;
Ulhøi, Benedicte P.;
Gardberg, Maria;
Aronica, Eleonora;
Hasselblatt, Martin;
Brück, Wolfgang;
Bielle, Franck

Publication type:

Article

Molecular progression of SHH-activated medulloblastomas.

Published in:

2019

By:

Korshunov, Andrey;
Okonechnikov, Konstantin;
Sahm, Felix;
Ryzhova, Marina;
Stichel, Damian;
Sievers, Philipp;
Meyer, Jochen;
Schrimpf, Daniel;
Zheludkova, Olga;
Golanov, Andrey;
Lichter, Peter;
Jones, David T. W.;
Pfister, Stefan M.;
von Deimling, Andreas;
Kool, Marcel

Publication type:

Letter

Mutational patterns and regulatory networks in epigenetic subgroups of meningioma.

Published in:

Acta Neuropathologica, 2019, v. 138, n. 2, p. 295, doi. 10.1007/s00401-019-02008-w

By:

Paramasivam, Nagarajan;
Hübschmann, Daniel;
Toprak, Umut H;
Ishaque, Naveed;
Neidert, Marian;
Schrimpf, Daniel;
Stichel, Damian;
Reuss, David;
Sievers, Philipp;
Reinhardt, Annekathrin;
Wefers, Annika K.;
Jones, David T. W.;
Gu, Zuguang;
Werner, Johannes;
Uhrig, Sebastian;
Wirsching, Hans-Georg;
Schick, Matthias;
Bewerunge-Hudler, Melanie;
Beck, Katja;
Brehmer, Stephanie

Publication type:

Article

Desmoplastic/nodular medulloblastomas (DNMB) and medulloblastomas with extensive nodularity (MBEN) disclose similar epigenetic signatures but different transcriptional profiles.

Published in:

Acta Neuropathologica, 2019, v. 137, n. 6, p. 1003, doi. 10.1007/s00401-019-01981-6

By:

Stichel, Damian;
Schrimpf, Daniel;
Casalini, Belen;
Sievers, Philipp;
Meyer, Jochen;
Sahm, Felix;
von Deimling, Andreas;
Korshunov, Andrey;
Jones, David T. W.;
Okonechnikov, Konstantin;
Kool, Marcel;
Pfister, Stefan M.;
Lichter, Peter;
Ryzhova, Marina;
Zheludkova, Olga;
Golanov, Andrey

Publication type:

Article

Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA.

Published in:

Acta Neuropathologica, 2019, v. 137, n. 5, p. 837, doi. 10.1007/s00401-019-01969-2

By:

Hou, Yanghao;
Pinheiro, Jorge;
Sahm, Felix;
Reuss, David E.;
Schrimpf, Daniel;
Stichel, Damian;
Casalini, Belén;
Koelsche, Christian;
Sievers, Philipp;
Wefers, Annika K.;
Reinhardt, Annekathrin;
Ebrahimi, Azadeh;
Fernández-Klett, Francisco;
Pusch, Stefan;
Meier, Jochen;
Schweizer, Leonille;
Paulus, Werner;
Prinz, Marco;
Hartmann, Christian;
Plate, Karl H.

Publication type:

Article

Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p.

Published in:

Acta Neuropathologica, 2018, v. 136, n. 6, p. 975, doi. 10.1007/s00401-018-1924-x

By:

Sievers, Philipp;
Stichel, Damian;
Hielscher, Thomas;
Schrimpf, Daniel;
Reinhardt, Annekathrin;
Wefers, Annika K.;
Reuss, David;
Jones, David T. W.;
Bewerunge-Hudler, Melanie;
Hartmann, Christian;
Baumgarten, Peter;
Wirsching, Hans-Georg;
Winther-Kristensen, Bjarne;
Brokinkel, Benjamin;
Ketter, Ralf;
Idoate Gastearena, Miguel Angel;
Lamszus, Katrin;
Seiz-Rosenhagen, Marcel;
Mawrin, Christian;
Harter, Patrick N.

Publication type:

Article