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Reversion mutations in germline BRCA1/2-mutant tumors reveal a BRCA-mediated phenotype in non-canonical histologies.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34109-8
By:
- Murciano-Goroff, Yonina R.;
- Schram, Alison M.;
- Rosen, Ezra Y.;
- Won, Helen;
- Gong, Yixiao;
- Noronha, Anne Marie;
- Janjigian, Yelena Y.;
- Stadler, Zsofia K.;
- Chang, Jason C.;
- Yang, Soo-Ryum;
- Mandelker, Diana;
- Offit, Kenneth;
- Berger, Michael F.;
- Donoghue, Mark T. A.;
- Bandlamudi, Chaitanya;
- Drilon, Alexander
Publication type:
Article
AKT mutant allele-specific activation dictates pharmacologic sensitivities.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29638-1
By:
- Shrestha Bhattarai, Tripti;
- Shamu, Tambudzai;
- Gorelick, Alexander N.;
- Chang, Matthew T.;
- Chakravarty, Debyani;
- Gavrila, Elena I.;
- Donoghue, Mark T. A.;
- Gao, JianJong;
- Patel, Swati;
- Gao, Sizhi Paul;
- Reynolds, Margaret H.;
- Phillips, Sarah M.;
- Soumerai, Tara;
- Abida, Wassim;
- Hyman, David M.;
- Schram, Alison M.;
- Solit, David B.;
- Smyth, Lillian M.;
- Taylor, Barry S.
Publication type:
Article
Haemophagocytic lymphohistiocytosis in adults: a multicentre case series over 7 years.
Published in:
British Journal of Haematology, 2016, v. 172, n. 3, p. 412, doi. 10.1111/bjh.13837
By:
- Schram, Alison M.;
- Comstock, Paige;
- Campo, Meghan;
- Gorovets, Daniel;
- Mullally, Ann;
- Bodio, Kelly;
- Arnason, Jon;
- Berliner, Nancy
Publication type:
Article
A germline JAK2 SNP is associated with predisposition to the development of JAK2<sup>V617F</sup>-positive myeloproliferative neoplasms.
Published in:
Nature Genetics, 2009, v. 41, n. 4, p. 455, doi. 10.1038/ng.342
By:
- Kilpivaara, Outi;
- Mukherjee, Semanti;
- Schram, Alison M.;
- Wadleigh, Martha;
- Mullally, Ann;
- Ebert, Benjamin L.;
- Bass, Adam;
- Marubayashi, Sachie;
- Heguy, Adriana;
- Garcia-Manero, Guillermo;
- Kantarjian, Hagop;
- Offit, Kenneth;
- Stone, Richard M.;
- Gilliland, D Gary;
- Klein, Robert J.;
- Levine, Ross L.
Publication type:
Article
Selective AKT kinase inhibitor capivasertib in combination with fulvestrant in PTEN-mutant ER-positive metastatic breast cancer.
Published in:
NPJ Breast Cancer, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41523-021-00251-7
By:
- Smyth, Lillian M.;
- Batist, Gerald;
- Meric-Bernstam, Funda;
- Kabos, Peter;
- Spanggaard, Iben;
- Lluch, Ana;
- Jhaveri, Komal;
- Varga, Andrea;
- Wong, Andrea;
- Schram, Alison M.;
- Ambrose, Helen;
- Carr, T. Hedley;
- de Bruin, Elza C.;
- Salinas-Souza, Carolina;
- Foxley, Andrew;
- Hauser, Joana;
- Lindemann, Justin P. O.;
- Maudsley, Rhiannon;
- McEwen, Robert;
- Moschetta, Michele
Publication type:
Article
Convergent evolution of BRCA2 reversion mutations under therapeutic pressure by PARP inhibition and platinum chemotherapy.
Published in:
NPJ Precision Oncology, 2024, v. 8, p. 1, doi. 10.1038/s41698-024-00526-9
By:
- Walmsley, Charlotte S.;
- Jonsson, Philip;
- Cheng, Michael L.;
- McBride, Sean;
- Kaeser, Christopher;
- Vargas, Herbert Alberto;
- Laudone, Vincent;
- Taylor, Barry S.;
- Kappagantula, Rajya;
- Baez, Priscilla;
- Richards, Allison L.;
- Noronha, Anne Marie;
- Perera, Dilmi;
- Berger, Michael;
- Solit, David B.;
- Iacobuzio-Donahue, Christine A.;
- Scher, Howard I.;
- Donoghue, Mark T. A.;
- Abida, Wassim;
- Schram, Alison M.
Publication type:
Article
Clinical and Morphologic Characteristics of Fibroblast Growth Factor Receptor Inhibitor-Associated Retinopathy.
Published in:
2021
By:
- Francis, Jasmine H.;
- Harding, James J.;
- Schram, Alison M.;
- Canestraro, Julia;
- Haggag-Lindgren, Dianna;
- Heinemann, Murk;
- Kriplani, Anuja;
- Jhaveri, Komal;
- Voss, Martin H.;
- Bajorin, Dean;
- Abou-Alfa, Ghassan K.;
- Iyer, Gopa;
- Drilon, Alexander;
- Rosenberg, Jonathan;
- Abramson, David H.
Publication type:
journal article
A phase Ib dose-escalation and expansion study of the oral MEK inhibitor pimasertib and PI3K/MTOR inhibitor voxtalisib in patients with advanced solid tumours.
Published in:
2018
By:
- Schram, Alison M.;
- Gandhi, Leena;
- Mita, Monica M.;
- Damstrup, Lars;
- Campana, Frank;
- Hidalgo, Manuel;
- Grande, Enrique;
- Hyman, David M.;
- Heist, Rebecca S.
Publication type:
journal article
NTRK1 Fusions identified by non-invasive plasma next-generation sequencing (NGS) across 9 cancer types.
Published in:
British Journal of Cancer, 2022, v. 126, n. 3, p. 514, doi. 10.1038/s41416-021-01536-1
By:
- Rolfo, Christian;
- Drilon, Alexander;
- Hong, David;
- McCoach, Caroline;
- Dowlati, Afshin;
- Lin, Jessica J.;
- Russo, Alessandro;
- Schram, Alison M.;
- Liu, Stephen V.;
- Nieva, Jorge J.;
- Nguyen, Timmy;
- Eshaghian, Shahrooz;
- Morse, Michael;
- Gettinger, Scott;
- Mobayed, Mohammad;
- Goldberg, Sarah;
- Araujo-Mino, Emilio;
- Vidula, Neelima;
- Bardia, Aditya;
- Subramanian, Janakiraman
Publication type:
Article
NTRK1 Fusions identified by non-invasive plasma next-generation sequencing (NGS) across 9 cancer types.
Published in:
2022
By:
- Rolfo, Christian;
- Drilon, Alexander;
- Hong, David;
- McCoach, Caroline;
- Dowlati, Afshin;
- Lin, Jessica J;
- Russo, Alessandro;
- Schram, Alison M;
- Liu, Stephen V;
- Nieva, Jorge J;
- Nguyen, Timmy;
- Eshaghian, Shahrooz;
- Morse, Michael;
- Gettinger, Scott;
- Mobayed, Mohammad;
- Goldberg, Sarah;
- Araujo-Mino, Emilio;
- Vidula, Neelima;
- Bardia, Aditya;
- Subramanian, Janakiraman
Publication type:
journal article
Precision oncology: Charting a path forward to broader deployment of genomic profiling.
Published in:
2017
By:
- Schram, Alison M.;
- Berger, Michael F.;
- Hyman, David M.
Publication type:
journal article
A Phase I Dose-Escalation Study of LY3405105, a Covalent Inhibitor of Cyclin-Dependent Kinase 7, Administered to Patients With Advanced Solid Tumors.
Published in:
Oncologist, 2024, v. 29, n. 1, p. e131, doi. 10.1093/oncolo/oyad215
By:
- Garralda, Elena;
- Schram, Alison M;
- Bedard, Philippe L;
- Schwartz, Gary K;
- Yuen, Eunice;
- McNeely, Samuel C;
- Ribeiro, Silvia;
- Cunningham, Jason;
- Wang, Yi;
- Urunuela, Arantxa;
- Xu, Xiaojian;
- LoRusso, Patricia
Publication type:
Article
The activity, safety, and evolving role of brigatinib in patients with ALK-rearranged non-small cell lung cancers.
Published in:
OncoTargets & Therapy, 2017, v. 10, p. 1983, doi. 10.2147/OTT.S109295
By:
- Sabari, Joshua K.;
- Santini, Fernando C.;
- Schram, Alison M.;
- Bergagnini, Isabella;
- Ruqin Chen;
- Mrad, Chebli;
- Lai, W. Victoria;
- Arbour, Kathryn C.;
- Drilon, Alexander
Publication type:
Article
Clinical implications of drug‐induced liver injury in early‐phase oncology clinical trials.
Published in:
Cancer (0008543X), 2020, v. 126, n. 22, p. 4967, doi. 10.1002/cncr.33153
By:
- Mondaca, Sebastian P.;
- Liu, Dazhi;
- Flynn, Jessica R.;
- Badson, Sandy;
- Hamaway, Stefan;
- Gounder, Mrinal M.;
- Khalil, Danny N.;
- Drilon, Alexander E.;
- Li, Bob T.;
- Jhaveri, Komal L.;
- Schram, Alison M.;
- Kargus, Katherine E.;
- Kasler, Mary Kate;
- Blauvelt, Natalie M.;
- Segal, Neil H.;
- Capanu, Marinela;
- Callahan, Margaret K.;
- Hyman, David M.;
- Gambarin‐Gelwan, Maya;
- Harding, James J.
Publication type:
Article

Found: 14