Works by Schousboe, Arne

Results: 185

Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia.

Published in:

Frontiers in Neuroscience, 2021, p. 1, doi. 10.3389/fnins.2021.646291

By:

Voss, Caroline M.;
Arildsen, Lene;
Nissen, Jakob D.;
Waagepetersen, Helle S.;
Schousboe, Arne;
Maechler, Pierre;
Ott, Peter;
Vilstrup, Hendrik;
Walls, Anne B.

Publication type:

Article

Immunocytochemical investigation of L-glutamic acid decarboxylase in the rat hippocampal formation: The influence of transient cerebral ischemia.

Published in:

Journal of Comparative Neurology, 1989, v. 281, n. 1, p. 40, doi. 10.1002/cne.902810105

By:

Johansen, Flemming-Fryd;
Lin, Chin-Tarng;
Schousboe, Arne;
Wu, Jang-Yen

Publication type:

Article

The Transcriptome and Metabolic Gene Signature of Protoplasmic Astrocytes in the Adult Murine Cortex.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 45, p. 12255, doi. 10.1523/JNEUROSCI.3404-07.2007

By:

Lovatt, Ditte;
Sonnewald, Ursula;
Waagepetersen, Helle S.;
Schousboe, Arne;
Wei He;
Lin, Jane H.-C.;
Xiaoning Han;
Takano, Takahiro;
Su Wang;
Sim, Fraser J.;
Goldman, Steven A.;
Nedergaard, Maiken

Publication type:

Article

A subconvulsive dose of kainate selectively compromises astrocytic metabolism in the mouse brain in vivo.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2014, v. 34, n. 8, p. 1340, doi. 10.1038/jcbfm.2014.88

By:

Walls, Anne B;
Eyjolfsson, Elvar M;
Schousboe, Arne;
Sonnewald, Ursula;
Waagepetersen, Helle S

Publication type:

Article

Effect of glutamine synthetase inhibition on brain and interorgan ammonia metabolism in bile duct ligated rats.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2014, v. 34, n. 3, p. 460, doi. 10.1038/jcbfm.2013.218

By:

Fries, Andreas W;
Dadsetan, Sherry;
Keiding, Susanne;
Bak, Lasse K;
Schousboe, Arne;
Waagepetersen, Helle S;
Simonsen, Mette;
Ott, Peter;
Vilstrup, Hendrik;
Sørensen, Michael

Publication type:

Article

Brain alanine formation as an ammonia-scavenging pathway during hyperammonemia: effects of glutamine synthetase inhibition in rats and astrocyte-neuron co-cultures.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2013, v. 33, n. 8, p. 1235, doi. 10.1038/jcbfm.2013.73

By:

Dadsetan, Sherry;
Kukolj, Eva;
Bak, Lasse K;
Sørensen, Michael;
Ott, Peter;
Vilstrup, Hendrik;
Schousboe, Arne;
Keiding, Susanne;
Waagepetersen, Helle S

Publication type:

Article

Quantitative importance of the pentose phosphate pathway determined by incorporation of 13C from [2-13C]- and [3-13C]glucose into TCA cycle intermediates and neurotransmitter amino acids in functionally intact neurons.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2012, v. 32, n. 9, p. 1788, doi. 10.1038/jcbfm.2012.85

By:

Brekke, Eva M F;
Walls, Anne B;
Schousboe, Arne;
Waagepetersen, Helle S;
Sonnewald, Ursula

Publication type:

Article

Exploring the GluR2 ligand-binding core in complex with the bicyclical.

Published in:

FEBS Journal, 2005, v. 272, n. 7, p. 1639, doi. 10.1111/j.1742-4658.2005.04583.x

By:

Nielsen, Bettina B.;
Pickering, Darryl S.;
Greenwood, Jeremy R.;
Brehm, Lotte;
Gajhede, Michael;
Schousboe, Arne;
Kastrup, Jette S

Publication type:

Article

Glutamate transport and metabolism in astrocytes.

Published in:

Glia (0894-1491), 1997, v. 21, n. 1, p. 56, doi. 10.1002/(SICI)1098-1136(199709)21:1<56::AID-GLIA6>3.0.CO;2-#

By:

Sonnewald, Ursula;
Westergaard, Niels;
Schousboe, Arne

Publication type:

Article

Trafficking between glia and neurons of TCA cycle intermediates and related metabolites.

Published in:

Glia (0894-1491), 1997, v. 21, n. 1, p. 99, doi. 10.1002/(SICI)1098-1136(199709)21:1<99::AID-GLIA11>3.0.CO;2-W

By:

Schousboe, Arne;
Westergaard, Niels;
Waagepetersen, Helle S.;
Larsson, Orla M.;
Bakken, Inger J.;
Sonnewald, Ursula

Publication type:

Article

Evaluation of the importance of transamination versus deamination in astrocytic metabolism of [U- 13C] glutamate.

Published in:

Glia (0894-1491), 1996, v. 17, n. 2, p. 160, doi. 10.1002/(SICI)1098-1136(199606)17:2<160::AID-GLIA7>3.0.CO;2-6

By:

Westergaard, Niels;
Drejer, Joan;
Schousboe, Arne;
Sonnewald, Ursula

Publication type:

Article

Purification and characterization of an astrocyte GABA-carrier inducing protein (GABA-CIP) released from cerebellar granule cells in culture.

Published in:

Glia (0894-1491), 1992, v. 6, n. 3, p. 236, doi. 10.1002/glia.440060311

By:

Nissen, Jan;
Schousboe, Arne;
Halkier, Torben;
Schousboe, Inger

Publication type:

Article

Release of taurine from astrocytes during potassium-evoked swelling.

Published in:

Glia (0894-1491), 1989, v. 2, n. 1, p. 45, doi. 10.1002/glia.440020105

By:

Pasantes-morales, Herminia;
Schousboe, Arne

Publication type:

Article

Structural correlates and cellular mechanisms in entorhinal-hippocampal dysfunction.

Published in:

Hippocampus, 1993, v. 3, p. 293, doi. 10.1002/hipo.1993.4500030732

By:

Arne Schousboe;
Bachevalier, Jocelyne;
Braak, Heiko;
Heinemann, Uwe;
Nitsch, Robert;
Schröder, Hannsjörg;
Wetmore, Cynthia

Publication type:

Article

Pathologic consequences in hippocampus of aberrations in the metabolic trafficking between neurons and glial cells necessary for normal glutamate homeostasis.

Published in:

Hippocampus, 1993, v. 3, p. 165, doi. 10.1002/hipo.1993.4500030720

By:

Arne DSc, Schousboe;
Westergaard, Niels

Publication type:

Article

Localization and pharmacological characterization of voltage dependent calcium channels in cultured neocortical neurons.

Published in:

International Journal of Developmental Neuroscience, 2001, v. 19, n. 1, p. 1, doi. 10.1016/S0736-5748(00)00091-5

By:

Timmermann, Daniel B.;
Lund, Trine M.;
Belhage, Bo;
Schousboe, Arne

Publication type:

Article

Effects of Adrenergic Agents on Intracellular Ca Homeostasis and Metabolism of Glucose in Astrocytes with an Emphasis on Pyruvate Carboxylation, Oxidative Decarboxylation and Recycling: Implications for Glutamate Neurotransmission and Excitotoxicity.

Published in:

Neurotoxicity Research, 2012, v. 21, n. 4, p. 405, doi. 10.1007/s12640-011-9296-1

By:

Obel, Linea;
Andersen, Karen;
Bak, Lasse;
Schousboe, Arne;
Waagepetersen, Helle

Publication type:

Article

Detoxification of Ammonia in Mouse Cortical GABAergic Cell Cultures Increases Neuronal Oxidative Metabolism and Reveals an Emerging Role for Release of Glucose-Derived Alanine.

Published in:

Neurotoxicity Research, 2011, v. 19, n. 3, p. 496, doi. 10.1007/s12640-010-9198-7

By:

Leke, Renata;
Bak, Lasse;
Anker, Malene;
Melø, Torun;
Sørensen, Michael;
Keiding, Susanne;
Vilstrup, Hendrik;
Ott, Peter;
Portela, Luis;
Sonnewald, Ursula;
Schousboe, Arne;
Waagepetersen, Helle

Publication type:

Article

Functional Importance of the Astrocytic Glycogen-Shunt and Glycolysis for Maintenance of an Intact Intra/Extracellular Glutamate Gradient.

Published in:

Neurotoxicity Research, 2010, v. 18, n. 1, p. 94, doi. 10.1007/s12640-010-9171-5

By:

Schousboe, Arne;
Sickmann, Helle M.;
Walls, Anne B.;
Bak, Lasse K.;
Waagepetersen, Helle S.

Publication type:

Article

ENERGY SUBSTRATES TO SUPPORT GLUTAMATERGIC SYNAPTIC FUNCTION: ROLE OF GLYCOGEN, GLUCOSE AND LACTATE.

Published in:

2008

By:

Schousboe, Arne;
Bak, Lasse;
Sickmann, Helle;
Sonnewald, Ursula;
Waagepetersen, Helle

Publication type:

Abstract

Energy Substrates to Support Glutamatergic and GABAergic Synaptic Function: Role of Glycogen, Glucose and Lactate.

Published in:

Neurotoxicity Research, 2007, v. 12, n. 4, p. 263, doi. 10.1007/BF03033909

By:

Schousboe, Arne;
Bak, Lasse k.;
Sickmann, Helle M.;
Sonnewald, Ursula;
Waagepetersen, Helle s.

Publication type:

Article

Astrocytic control of biosynthesis and turnover of the neurotransmitters glutamate and GABA.

Published in:

Frontiers in Endocrinology, 2013, v. 4, p. 1, doi. 10.3389/fendo.2013.00102

By:

Schousboe, Arne;
Bak, Lasse K.;
Waagepetersen, Helle S.

Publication type:

Article

Development of Excitatory Amino Acid Dependent 45Ca2+ Uptake in Cultured Cerebral Cortex Neurons.

Published in:

Annals of the New York Academy of Sciences, 1989, v. 560, n. 1, p. 454, doi. 10.1111/j.1749-6632.1989.tb24135.x

By:

FRANDSEN, AASE;
DREJER, JØRGEN;
SCHOUSBOE, ARNE

Publication type:

Article

Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes.

Published in:

Glia (0894-1491), 2017, v. 65, n. 3, p. 474, doi. 10.1002/glia.23105

By:

Nissen, Jakob D.;
Lykke, Kasper;
Bryk, Jaroslaw;
Stridh, Malin H.;
Zaganas, Ioannis;
Skytt, Dorte M.;
Schousboe, Arne;
Bak, Lasse K.;
Enard, Wolfgang;
Pääbo, Svante;
Waagepetersen, Helle S.

Publication type:

Article

Astrocyte glycogenolysis is triggered by store-operated calcium entry and provides metabolic energy for cellular calcium homeostasis.

Published in:

Glia (0894-1491), 2014, v. 62, n. 4, p. 526, doi. 10.1002/glia.22623

By:

Müller, Margit S.;
Fox, Rebecca;
Schousboe, Arne;
Waagepetersen, Helle S.;
Bak, Lasse K.

Publication type:

Article

Direct measurement of backflux between oxaloacetate and fumarate following pyruvate carboxylation.

Published in:

Glia (0894-1491), 2012, v. 60, n. 1, p. 147, doi. 10.1002/glia.21265

By:

Brekke, Eva;
Walls, Anne B.;
Nørfeldt, Lasse;
Schousboe, Arne;
Waagepetersen, Helle S.;
Sonnewald, Ursula

Publication type:

Article

Cellular mitochondrial heterogeneity in cultured astrocytes as demonstrated by immunogold labeling of α‐ketoglutarate dehydrogenase.

Published in:

Glia (0894-1491), 2006, v. 53, n. 2, p. 225, doi. 10.1002/glia.20276

By:

Helle S. Waagepetersen;
Gert H. Hansen;
Kirsten Fenger;
J. Gordon Lindsay;
Gary Gibson;
Arne Schousboe

Publication type:

Article

Glutamine-induced free radical production in cultured astrocytes.

Published in:

Glia (0894-1491), 2004, v. 46, n. 3, p. 296, doi. 10.1002/glia.20003

By:

Arumugam R. Jayakumar;
K.V. Rama Rao;
Arne Schousboe

Publication type:

Article

Multiple compartments with different metabolic characteristics are involved in biosynthesis of intracellular and released glutamine and citrate in astrocytes.

Published in:

Glia (0894-1491), 2001, v. 35, n. 3, p. 246, doi. 10.1002/glia.1089

By:

Waagepetersen, Helle S.;
Sonnewald, Ursula;
Larsson, Orla M.;
Schousboe, Arne

Publication type:

Article

The 13th International Conference on Brain Energy Metabolism: "How Metabolism Dictates Neurotransmission, Function and Behavior".

Published in:

Journal of Neuroscience Research, 2019, v. 97, n. 8, p. 849, doi. 10.1002/jnr.24445

By:

Barros, L. Felipe;
Schousboe, Arne;
McKenna, Mary C.

Publication type:

Article

Astrocytic pyruvate carboxylation: Status after 35 years.

Published in:

Journal of Neuroscience Research, 2019, v. 97, n. 8, p. 890, doi. 10.1002/jnr.24402

By:

Schousboe, Arne;
Waagepetersen, Helle S.;
Sonnewald, Ursula

Publication type:

Article

In Memoriam: Jean de Vellis (1935–2018).

Published in:

Journal of Neuroscience Research, 2018, v. 96, n. 5, p. 755, doi. 10.1002/jnr.24233

By:

Bongarzone, Ernesto R.;
McKenna, Mary C.;
Espinosa‐Jeffrey, Araceli;
Wainwright, Nancy;
Ghiani, Cristina;
Perez‐Polo, J. Regino;
Schousboe, Arne;
Prager, Eric M.

Publication type:

Article

Specificity of exogenous acetate and glutamate as astrocyte substrates examined in acute brain slices from female mice using methionine sulfoximine (MSO) to inhibit glutamine synthesis.

Published in:

Journal of Neuroscience Research, 2017, v. 95, n. 11, p. 2207, doi. 10.1002/jnr.24038

By:

Andersen, Jens Velde;
McNair, Laura Frendrup;
Schousboe, Arne;
Waagepetersen, Helle Sønderby

Publication type:

Article

The novel anticonvulsant neuropeptide and galanin analogue, NAX-5055, does not alter energy and amino acid metabolism in cultured brain cells.

Published in:

Journal of Neuroscience Research, 2017, v. 95, n. 11, p. 2286, doi. 10.1002/jnr.24057

By:

Aldana, Blanca I.;
Waagepetersen, Helle S.;
Schousboe, Arne;
White, H. Steve;
Bulaj, Grzegorz;
Walls, Anne B.

Publication type:

Article

The 12th International Conference on Brain Energy Metabolism (ICBEM): 'Energy Metabolism and Neuron-Glia Interactions in Brain: From Molecular Mechanisms to Novel Therapeutic Approaches'.

Published in:

2017

By:

Yu, Albert C. H.;
Schousboe, Arne;
McKenna, Mary C.

Publication type:

Editorial

Misconceptions regarding basic thermodynamics and enzyme kinetics have led to erroneous conclusions regarding the metabolic importance of lactate dehydrogenase isoenzyme expression.

Published in:

Journal of Neuroscience Research, 2017, v. 95, n. 11, p. 2098, doi. 10.1002/jnr.23994

By:

Bak, Lasse K.;
Schousboe, Arne

Publication type:

Article

Glutamate oxidation in astrocytes: Roles of glutamate dehydrogenase and aminotransferases.

Published in:

Journal of Neuroscience Research, 2016, v. 94, n. 12, p. 1561, doi. 10.1002/jnr.23908

By:

McKenna, Mary C.;
Stridh, Malin H.;
McNair, Laura F.;
Sonnewald, Ursula;
Waagepetersen, Helle S.;
Schousboe, Arne

Publication type:

Article

Glucose replaces glutamate as energy substrate to fuel glutamate uptake in glutamate dehydrogenase-deficient astrocytes.

Published in:

Journal of Neuroscience Research, 2015, v. 93, n. 7, p. 1093, doi. 10.1002/jnr.23568

By:

Pajęcka, Kamilla;
Nissen, Jakob D.;
Stridh, Malin H.;
Skytt, Dorte M.;
Schousboe, Arne;
Waagepetersen, Helle S.

Publication type:

Article

The 11th International Conference on Brain Energy Metabolism 'how energy metabolism shapes brain function'.

Published in:

2015

By:

Waagepetersen, Helle;
Schousboe, Arne;
McKenna, Mary C.

Publication type:

Other

Valine but not leucine or isoleucine supports neurotransmitter glutamate synthesis during synaptic activity in cultured cerebellar neurons.

Published in:

Journal of Neuroscience Research, 2012, v. 90, n. 9, p. 1768, doi. 10.1002/jnr.23072

By:

Bak, Lasse K.;
Johansen, Maja L.;
Schousboe, Arne;
Waagepetersen, Helle S.

Publication type:

Article

Preface.

Published in:

Journal of Neuroscience Research, 2011, v. 89, n. 12, p. 1895, doi. 10.1002/jnr.22782

By:

Adam-Vizi, Vera;
Dienel, Gerald A.;
Schousboe, Arne;
McKenna, Mary C.

Publication type:

Article

Glial Glutamine Homeostasis in Health and Disease.

Published in:

2023

By:

Andersen, Jens V.;
Schousboe, Arne

Publication type:

Literature Review

Preface for the Vladimir Parpura Honorary Issue of Neurochemical Research.

Published in:

Neurochemical Research, 2021, v. 46, n. 10, p. 2507, doi. 10.1007/s11064-021-03426-7

By:

Verkhratsky, Alexei;
Schousboe, Arne;
Zorec, Robert

Publication type:

Article

Two Metabolic Fuels, Glucose and Lactate, Differentially Modulate Exocytotic Glutamate Release from Cultured Astrocytes.

Published in:

Neurochemical Research, 2021, v. 46, n. 10, p. 2551, doi. 10.1007/s11064-021-03340-y

By:

Montana, Vedrana;
Flint, Daniel;
Waagepetersen, Helle S.;
Schousboe, Arne;
Parpura, Vladimir

Publication type:

Article

Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease.

Published in:

Neurochemical Research, 2021, v. 46, n. 10, p. 2676, doi. 10.1007/s11064-021-03276-3

By:

Salcedo, Claudia;
Wagner, Antonie;
Andersen, Jens V.;
Vinten, Kasper Tore;
Waagepetersen, Helle S.;
Schousboe, Arne;
Freude, Kristine K.;
Aldana, Blanca I.

Publication type:

Article

Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects.

Published in:

Neurochemical Research, 2020, v. 45, n. 7, p. 1551, doi. 10.1007/s11064-020-03017-y

By:

Lie, Maria E. K.;
Kickinger, Stefanie;
Skovgaard-Petersen, Jonas;
Ecker, Gerhard F.;
Clausen, Rasmus P.;
Schousboe, Arne;
White, H. Steve;
Wellendorph, Petrine

Publication type:

Article

Preface for the Vittorio Gallo Honorary Issue of Neurochemical Research.

Published in:

2020

By:

Schousboe, Arne

Publication type:

Editorial

Astrocytic Metabolism Focusing on Glutamate Homeostasis: A Short Review Dedicated to Vittorio Gallo.

Published in:

Neurochemical Research, 2020, v. 45, n. 3, p. 522, doi. 10.1007/s11064-019-02888-0

By:

Schousboe, Arne

Publication type:

Article

Special Issue in Honor of Dr. Elias K. Michaelis.

Published in:

2019

By:

Choi, In-Young;
Schousboe, Arne

Publication type:

Biography

Correction to: Delineation of the Role of Astroglial GABA Transporters in Seizure Control.

Published in:

2018

By:

Schousboe, Arne;
Madsen, Karsten K.

Publication type:

Correction Notice