Works by Schork, Nicholas J.

Results: 170

Association of direct-to-consumer genome-wide disease risk estimates and self-reported disease.

Published in:

Genetic Epidemiology, 2012, v. 36, n. 1, p. 66, doi. 10.1002/gepi.20664

By:

Bloss, Cinnamon S.;
Topol, Eric J.;
Schork, Nicholas J.

Publication type:

Article

Powerful designs for genetic association studies that consider twins and sibling pairs with discordant genotypes.

Published in:

Genetic Epidemiology, 2007, v. 31, n. 7, p. 789, doi. 10.1002/gepi.20241

By:

Wessel, Jennifer;
Schork, Andrew J.;
Tiwari, Hemant K.;
Schork, Nicholas J.

Publication type:

Article

Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the Family Blood Pressure Program.

Published in:

Genetic Epidemiology, 2007, v. 31, n. 3, p. 195, doi. 10.1002/gepi.20202

By:

Greenwood, Tiffany A.;
Libiger, Ondrej;
Kardia, Sharon;
Hanis, Craig;
Morrison, Alanna C.;
Gu, C. Charles;
Rice, Treva;
Miller, Michael;
Turner, Stephen T.;
Myers, Richard H.;
Grove, John;
Hsiao, Chin-Fu;
Weder, Alan B.;
Schork, Nicholas J.

Publication type:

Article

Two-Trait-Locus Linkage Analyses of Asthma Susceptibility.

Published in:

Genetic Epidemiology, 2001, v. 21, p. S278, doi. 10.1002/gepi.2001.21.s1.s278

By:

Nath, Swapan K.;
Chen, Chien-Hsiun;
Schork, Nicholas J.

Publication type:

Article

Detection of genetic heterogeneity for complex quantitative phenotypes.

Published in:

Genetic Epidemiology, 1992, v. 9, n. 3, p. 207, doi. 10.1002/gepi.1370090307

By:

Schork, Nicholas J.;
Chakravarti, Aravinda

Publication type:

Article

Extended pedigree patterned covariance matrix mixed models for quantitative phenotype analysis.

Published in:

Genetic Epidemiology, 1992, v. 9, n. 2, p. 73, doi. 10.1002/gepi.1370090202

By:

Schork, Nicholas J.;
Vogler, G. P.

Publication type:

Article

On the asymmetry of biological frequency distributions.

Published in:

Genetic Epidemiology, 1990, v. 7, n. 6, p. 427, doi. 10.1002/gepi.1370070605

By:

Schork, Nicholas J.;
Weder, Alan B.;
Schork, M. Anthony;
Rao, D. C.

Publication type:

Article

Functional expression of dental plaque microbiota.

Published in:

Frontiers in Cellular & Infection Microbiology, 2014, p. 1, doi. 10.3389/fcimb.2014.00108

By:

Peterson, Scott N.;
Meissner, Tobias;
Su, Andrew I.;
Snesrud, Erik;
Ong, Ana C.;
Schork, Nicholas J.;
Bretz, Walter A.;
Banas, Jeff;
Iebba, Valerio

Publication type:

Article

Characterization of Circulating Endothelial Cells in Acute Myocardial Infarction.

Published in:

Science Translational Medicine, 2012, v. 4, n. 126, p. 1, doi. 10.1126/scitranslmed.3003451

By:

Damani, Samir;
Bacconi, Andrea;
Libiger, Ondrej;
Chourasia, Aparajita H.;
Serry, Rod;
Gollapudi, Raghava;
Goldberg, Ron;
Rapeport, Kevin;
Haaser, Sharon;
Topol, Sarah;
Knowlton, Sharen;
Bethel, Kelly;
Kuhn, Peter;
Wood, Malcolm;
Carragher, Bridget;
Schork, Nicholas J.;
Jiang, John;
Rao, Chandra;
Connelly, Mark;
Fowler, Velia M.

Publication type:

Article

Digital Medicine and the Scripps Translational Science Institute.

Published in:

2011

By:

Topol, Eric J.;
Schork, Nicholas J.;
Smith, Joseph M.

Publication type:

Other

Strategies for Testing Intervention Matching Schemes in Cancer.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 3, p. 542, doi. 10.1002/cpt.1947

By:

Schork, Nicholas J.;
Goetz, Laura H.;
Lowey, James;
Trent, Jeffrey

Publication type:

Article

Genetic subtypes of Alzheimer's disease are related to differential biomarker and cognitive trajectories.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.093276

By:

Elman, Jeremy A.;
Schork, Nicholas J.;
Rangan, Aaditya V

Publication type:

Article

Polygenic risk score analysis suggests hypothyroidism as a risk factor for Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.088329

By:

Piras, Ignazio;
Naymik, Marcus;
Don, Janith;
Schork, Nicholas J.;
Saner, Don;
Huentelman, Matthew J.

Publication type:

Article

Identification of ALK as a major familial neuroblastoma predisposition gene.

Published in:

Nature, 2008, v. 455, n. 7215, p. 930, doi. 10.1038/nature07261

By:

Mossé, Yaël P.;
Laudenslager, Marci;
Longo, Luca;
Cole, Kristina A.;
Wood, Andrew;
Attiyeh, Edward F.;
Laquaglia, Michael J.;
Sennett, Rachel;
Lynch, Jill E.;
Perri, Patrizia;
Laureys, Geneviève;
Speleman, Frank;
Kim, Cecilia;
Hou, Cuiping;
Hakonarson, Hakon;
Torkamani, Ali;
Schork, Nicholas J.;
Brodeur, Garrett M.;
Tonini, Gian P.;
Rappaport, Eric

Publication type:

Article

Methylenetetrahydrofolate reductase (MTHFR) polymorphism A1298C (Glu429Ala) predicts decline in renal function over time in the African-American Study of Kidney Disease and Hypertension (AASK) Trial and Veterans Affairs Hypertension Cohort (VAHC).

Published in:

Nephrology Dialysis Transplantation, 2012, v. 27, n. 1, p. 197, doi. 10.1093/ndt/gfr257

By:

Fung, Maple M.;
Salem, Rany M.;
Lipkowitz, Michael S.;
Bhatnagar, Vibha;
Pandey, Braj;
Schork, Nicholas J.;
O’Connor, Daniel T.

Publication type:

Article

Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis.

Published in:

Nephrology Dialysis Transplantation, 2009, v. 24, n. 12, p. 3677, doi. 10.1093/ndt/gfp471

By:

Fung, Maple M.;
Chen, Yuqing;
Lipkowitz, Michael S.;
Salem, Rany M.;
Bhatnagar, Vibha;
Mahata, Manjula;
Nievergelt, Caroline M.;
Rao, Fangwen;
Mahata, Sushil K.;
Schork, Nicholas J.;
Brophy, Victoria H.;
O'Connor, Daniel T.

Publication type:

Article

The VA Hypertension Primary Care Longitudinal Cohort: Electronic medical records in the post-genomic era.

Published in:

Health Informatics Journal, 2010, v. 16, n. 4, p. 274, doi. 10.1177/1460458210380527

By:

Salem, Rany M.;
Pandey, Braj;
Richard, Erin;
Fung, Maple M.;
Garcia, Erin P.;
Brophy, Victoria H.;
Schork, Nicholas J.;
O'Connor, Daniel T.;
Bhatnagar, Vibha

Publication type:

Article

A High Resolution Case Study of a Patient with Recurrent Plasmodium vivax Infections Shows That Relapses Were Caused by Meiotic Siblings.

Published in:

PLoS Neglected Tropical Diseases, 2014, v. 8, n. 6, p. 1, doi. 10.1371/journal.pntd.0002882

By:

Bright, Andrew Taylor;
Manary, Micah J.;
Tewhey, Ryan;
Arango, Eliana M.;
Wang, Tina;
Schork, Nicholas J.;
Yanow, Stephanie K.;
Winzeler, Elizabeth A.

Publication type:

Article

A High Resolution Case Study of a Patient with Recurrent <i>Plasmodium vivax</i> Infections Shows That Relapses Were Caused by Meiotic Siblings.

Published in:

2014

By:

Bright, Andrew Taylor;
Manary, Micah J.;
Tewhey, Ryan;
Arango, Eliana M.;
Wang, Tina;
Schork, Nicholas J.;
Yanow, Stephanie K.;
Winzeler, Elizabeth A.

Publication type:

Case Study

A simulation-based analysis of chromosome segment sharing among a group of arbitrarily related individuals.

Published in:

European Journal of Human Genetics, 2007, v. 15, n. 12, p. 1260, doi. 10.1038/sj.ejhg.5201910

By:

Libiger, Ondrej;
Schork, Nicholas J.

Publication type:

Article

The impact of data quality on the identification of complex disease genes: experience from the Family Blood Pressure Program.

Published in:

European Journal of Human Genetics, 2006, v. 14, n. 4, p. 469, doi. 10.1038/sj.ejhg.5201582

By:

Chang, Yen-Pei Christy;
Kim, James Dae-Ok;
Schwander, Karen;
Rao, Dabeeru C.;
Miller, Mike B.;
Weder, Alan B.;
Cooper, Richard S.;
Schork, Nicholas J.;
Province, Michael A.;
Morrison, Alanna C.;
Kardia, Sharon L. R.;
Quertermous, Thomas;
Chakravarti, Aravinda

Publication type:

Article

Sampling guidelines for testing secondary attack rates associated with short-latency infectious diseases.

Published in:

1994

By:

Schork, Nicholas J.;
Schork, N J

Publication type:

journal article

Disease entities, mixed multi-normal distributions, and the role of the hyperkinetic state in the pathogenesis of hypertension.

Published in:

Statistics in Medicine, 1990, v. 9, n. 3, p. 301, doi. 10.1002/sim.4780090313

By:

Schork, Nicholas J.;
Weder, Alan B.;
Schork, M. Anthony;
Bassett, David R.;
Julius, Stevo

Publication type:

Article

Not so lost in the genetic crowd.

Published in:

Nature Genetics, 2009, v. 41, n. 11, p. 1163, doi. 10.1038/ng1109-1163

By:

Schork, Nicholas J.;
Bansal, Vikas

Publication type:

Article

The insulin gene VNTR is associated with fasting insulin levels and development of juvenile obesity.

Published in:

Nature Genetics, 2000, v. 26, n. 4, p. 444, doi. 10.1038/82579

By:

Le Stunff, Catherine;
Fallin, Daniele;
Schork, Nicholas J.;
Bougnères, Pierre

Publication type:

Article

All SNPs Are Not Created Equal: Genome-Wide Association Studies Reveal a Consistent Pattern of Enrichment among Functionally Annotated SNPs.

Published in:

PLoS Genetics, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.pgen.1003449

By:

Schork, Andrew J.;
Thompson, Wesley K.;
Pham, Phillip;
Torkamani, Ali;
Roddey, J. Cooper;
Sullivan, Patrick F.;
Kelsoe, John R.;
O''Donovan, Michael C.;
Furberg, Helena;
Schork, Nicholas J.;
Andreassen, Ole A.;
Dale, Anders M.

Publication type:

Article

Complex Patterns of Genomic Admixture within Southern Africa.

Published in:

PLoS Genetics, 2013, v. 9, n. 3, p. 1, doi. 10.1371/journal.pgen.1003309

By:

Petersen, Desiree C.;
Libiger, Ondrej;
Tindall, Elizabeth A.;
Hardie, Rae-Anne;
Hannick, Linda I.;
Glashoff, Richard H.;
Mukerji, Mitali;
Fernandez, Pedro;
Haacke, Wilfrid;
Schork, Nicholas J.;
Hayes, Vanessa M.

Publication type:

Article

Age-Dependent Brain Gene Expression and Copy Number Anomalies in Autism Suggest Distinct Pathological Processes at Young Versus Mature Ages.

Published in:

PLoS Genetics, 2012, v. 8, n. 3, p. 1, doi. 10.1371/journal.pgen.1002592

By:

Chow, Maggie L.;
Pramparo, Tiziano;
Winn, Mary E.;
Barnes, Cynthia Carter;
Hai-Ri Li;
Weiss, Lauren;
Jian-Bing Fan;
Murray, Sarah;
April, Craig;
Belinson, Haim;
Xiang-Dong Fu;
Wynshaw-Boris, Anthony;
Schork, Nicholas J.;
Courchesne, Eric

Publication type:

Article

An Assessment of the Individual and Collective Effects of Variants on Height Using Twins and a Developmentally Informative Study Design.

Published in:

PLoS Genetics, 2011, v. 7, n. 12, p. 1, doi. 10.1371/journal.pgen.1002413

By:

Vrieze, Scott I.;
McGue, Matt;
Miller, Michael B.;
Legrand, Lisa N.;
Schork, Nicholas J.;
Iacono, William G.

Publication type:

Article

Global Developmental Gene Expression and Pathway Analysis of Normal Brain Development and Mouse Models of Human Neuronal Migration Defects.

Published in:

PLoS Genetics, 2011, v. 7, n. 3, p. 1, doi. 10.1371/journal.pgen.1001331

By:

Pramparo, Tiziano;
Libiger, Ondrej;
Jain, Sonia;
Hong Li;
Yong Ha Youn;
Hirotsune, Shinji;
Schork, Nicholas J.;
Wynshaw-Boris, Anthony

Publication type:

Article

Mechanisms Underlying Hypoxia Tolerance in Drosophila melanogaster: hairy as a Metabolic Switch.

Published in:

PLoS Genetics, 2008, v. 4, n. 10, p. 1, doi. 10.1371/journal.pgen.1000221

By:

Zhou, Dan;
Jin Xue;
Lai, James C. K.;
Schork, Nicholas J.;
White, Kevin P.;
Haddad, Gabriel G.

Publication type:

Article

Generalized Analysis of Molecular Variance.

Published in:

PLoS Genetics, 2007, v. 3, n. 4, p. e51, doi. 10.1371/journal.pgen.0030051

By:

Nievergelt, Caroline M.;
Libiger, Ondrej;
Schork, Nicholas J.

Publication type:

Article

Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk.

Published in:

2007

By:

Zhang, Lian;
Rao, Fangwen;
Zhang, Kuixing;
Khandrika, Srikrishna;
Das, Madhusudan;
Vaingankar, Sucheta M.;
Xuping Bao;
Rana, Brinda K.;
Smith, Douglas W.;
Wessel, Jennifer;
Salem, Rany M.;
Rodriguez-Flores, Juan L.;
Mahata, Sushil K.;
Schork, Nicholas J.;
Ziegler, Michael G.;
O'Connor, Daniel T.;
Bao, Xuping

Publication type:

journal article

Admixture and Clinical Phenotypic Variation.

Published in:

Human Heredity, 2014, v. 77, n. 1-4, p. 73, doi. 10.1159/000362233

By:

Goetz, Laura H.;
Uribe-Bruce, Liliana;
Quarless, Danjuma;
Libiger, Ondrej;
Schork, Nicholas J.

Publication type:

Article

A Geographic Cline of Skull and Brain Morphology among Individuals of European Ancestry.

Published in:

Human Heredity, 2011, v. 72, n. 1, p. 35, doi. 10.1159/000330168

By:

Bakken, Trygve E.;
Dale, Anders M.;
Schork, Nicholas J.

Publication type:

Article

Extreme Selection Strategies in Gene Mapping Studies of Oligogenic Quantitative Traits Do Not Always Increase Power.

Published in:

Human Heredity, 1998, v. 48, n. 2, p. 97, doi. 10.1159/000022788

By:

Allison, David B.;
Heo, Moonseong;
Schork, Nicholas J.;
Wong, Su-Ling;
Elston, Robert C.

Publication type:

Article

The Relative Efficiency and Power of Small-Pedigree Studies of the Heritability of a Quantitative Trait.

Published in:

Human Heredity, 1993, v. 43, n. 1, p. 1, doi. 10.1159/000154106

By:

Schork, Nicholas J.;
Schork, Anthony

Publication type:

Article

Accurate prediction of deleterious protein kinase polymorphisms.

Published in:

Bioinformatics, 2007, v. 23, n. 21, p. 2918, doi. 10.1093/bioinformatics/btm437

By:

Ali Torkamani;
Nicholas J. Schork

Publication type:

Article

Association Between Traumatic Brain Injury and Risk of Posttraumatic Stress Disorder in Active-Duty Marines.

Published in:

JAMA Psychiatry, 2014, v. 71, n. 2, p. 149, doi. 10.1001/jamapsychiatry.2013.3080

By:

Yurgil, Kate A.;
Barkauskas, Donald A.;
Vasterling, Jennifer J.;
Nievergelt, Caroline M.;
Larson, Gerald E.;
Schork, Nicholas J.;
Litz, Brett T.;
Nash, William P.;
Baker, Dewleen G.

Publication type:

Article

Comprehensive analysis of treatment response phenotypes in rheumatoid arthritis for pharmacogenetic studies.

Published in:

Arthritis Research & Therapy, 2017, v. 19, p. 1, doi. 10.1186/s13075-017-1299-8

By:

Standish, Kristopher A.;
Huang, C. Chris;
Curran, Mark E.;
Schork, Nicholas J.

Publication type:

Article

The Combined Effect of Common Genetic Risk Variants on Circulating Lipoproteins Is Evident in Childhood: A Longitudinal Analysis of the Cardiovascular Risk in Young Finns Study.

Published in:

PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0146081

By:

Buscot, Marie-jeanne;
Magnussen, Costan G.;
Juonala, Markus;
Pitkänen, Niina;
Lehtimäki, Terho;
Viikari, Jorma S. A.;
Kähönen, Mika;
Hutri-Kähönen, Nina;
Schork, Nicholas J.;
Raitakari, Olli T.;
Thomson, Russell J.

Publication type:

Article

The Consortium on the Genetics of Endophenotypes in Schizophrenia: Model Recruitment, Assessment, and Endophenotyping Methods for a Multisite Collaboration.

Published in:

Schizophrenia Bulletin, 2007, v. 33, n. 1, p. 33

By:

Calkins, Monica E.;
Dobie, Dorcas J.;
Cadenhead, Kristin S.;
Olincy, Ann;
Freedman, Robert;
Green, Michael F.;
Greenwood, Tiffany A.;
Gur, Raquel E.;
Gur, Ruben C.;
Light, Gregory A.;
Mintz, Jim;
Nuechterlein, Keith H.;
Radant, Allen D.;
Schork, Nicholas J.;
Seidman, Larry J.;
Siever, Larry J.;
Silverman, Jeremy M.;
Stone, William S.;
Swerdlow, Neal R.;
Tsuang, Debby W.

Publication type:

Article

Statistical Genetics Concepts and Approaches in Schizophrenia and Related Neuropsychiatric Research.

Published in:

Schizophrenia Bulletin, 2007, v. 33, n. 1, p. 95

By:

Schork, Nicholas J.;
Greenwood, Tiffany A.;
Braff, David L.

Publication type:

Article

Deconstructing Schizophrenia: An Overview of the Use of Endophenotypes in Order to Understand a Complex Disorder.

Published in:

Schizophrenia Bulletin, 2007, v. 33, n. 1, p. 21

By:

Braff, David L.;
Freedman, Robert;
Schork, Nicholas J.;
Gottesman, Irving I.

Publication type:

Article

Antisaccade performance in schizophrenia patients, their first-degree biological relatives, and community comparison subjects: Data from the COGS study.

Published in:

Psychophysiology, 2010, v. 47, n. 5, p. 846, doi. 10.1111/j.1469-8986.2010.01004.x

By:

Radant, Allen D.;
Dobie, Dorcas J.;
Calkins, Monica E.;
Olincy, Ann;
Braff, David L.;
Cadenhead, Kristin S.;
Freedman, Robert;
Green, Michael F.;
Greenwood, Tiffany A.;
Gur, Raquel E.;
Gur, Ruben C.;
Light, Gregory A.;
Meichle, Sean P.;
Millard, Steve P.;
Mintz, Jim;
Nuechterlein, Keith H.;
Schork, Nicholas J.;
Seidman, Larry J.;
Siever, Larry J.;
Silverman, Jeremy M.

Publication type:

Article

A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 116, doi. 10.3390/ijms24010116

By:

Bae, Harold;
Gurinovich, Anastasia;
Karagiannis, Tanya T.;
Song, Zeyuan;
Leshchyk, Anastasia;
Li, Mengze;
Andersen, Stacy L.;
Arbeev, Konstantin;
Yashin, Anatoliy;
Zmuda, Joseph;
An, Ping;
Feitosa, Mary;
Giuliani, Cristina;
Franceschi, Claudio;
Garagnani, Paolo;
Mengel-From, Jonas;
Atzmon, Gil;
Barzilai, Nir;
Puca, Annibale;
Schork, Nicholas J.

Publication type:

Article

Hepatic PEMT Expression Decreases with Increasing NAFLD Severity.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 9296, doi. 10.3390/ijms23169296

By:

Piras, Ignazio S.;
Raju, Anish;
Don, Janith;
Schork, Nicholas J.;
Gerhard, Glenn S.;
DiStefano, Johanna K.

Publication type:

Article

Rare variant phasing using paired tumor:normal sequence data.

Published in:

BMC Bioinformatics, 2019, v. 20, n. 1, p. 1, doi. 10.1186/s12859-019-2753-1

By:

Buckley, Alexandra R.;
Ideker, Trey;
Carter, Hannah;
Schork, Nicholas J.

Publication type:

Article

A time-series analysis of blood-based biomarkers within a 25-year longitudinal dolphin cohort.

Published in:

PLoS Computational Biology, 2023, v. 19, n. 2, p. 1, doi. 10.1371/journal.pcbi.1010890

By:

Rangan, Aaditya V.;
McGrouther, Caroline C.;
Bhadra, Nivedita;
Venn-Watson, Stephanie;
Jensen, Eric D.;
Schork, Nicholas J.

Publication type:

Article

Skewness and mixtures of normal distributions.

Published in:

Communications in Statistics: Theory & Methods, 1988, v. 17, n. 11, p. 3951, doi. 10.1080/03610928808829848

By:

Schork, Nicholas J.;
Schork, M. Anthony

Publication type:

Article