Works by Schneider, Gunter

Results: 99

MTOR inhibitor-based combination therapies for pancreatic cancer.

Published in:

2018

By:

Hassan, Zonera;
Schneeweis, Christian;
Wirth, Matthias;
Veltkamp, Christian;
Dantes, Zahra;
Feuerecker, Benedikt;
Ceyhan, Güralp O;
Knauer, Shirley K;
Weichert, Wilko;
Schmid, Roland M;
Stauber, Roland;
Arlt, Alexander;
Krämer, Oliver H;
Rad, Roland;
Reichert, Maximilian;
Saur, Dieter;
Schneider, Günter;
Ceyhan, Güralp O;
Krämer, Oliver H;
Schneider, Günter

Publication type:

journal article

Structural and Mutagenesis Studies of the Thiamine‐Dependent, Ketone‐Accepting YerE from Pseudomonas protegens.

Published in:

ChemBioChem, 2018, v. 19, n. 21, p. 2283, doi. 10.1002/cbic.201800325

By:

Hampel, Sabrina;
Steitz, Jan‐Patrick;
Baierl, Anna;
Lehwald, Patrizia;
Wiesli, Luzia;
Richter, Michael;
Fries, Alexander;
Pohl, Martina;
Schneider, Gunter;
Dobritzsch, Doreen;
Müller, Michael

Publication type:

Article

Targeting the ubiquitin‐proteasome system in a pancreatic cancer subtype with hyperactive MYC.

Published in:

Molecular Oncology, 2020, v. 14, n. 12, p. 3048, doi. 10.1002/1878-0261.12835

By:

Lankes, Katharina;
Hassan, Zonera;
Doffo, María Josefina;
Schneeweis, Christian;
Lier, Svenja;
Öllinger, Rupert;
Rad, Roland;
Krämer, Oliver H.;
Keller, Ulrich;
Saur, Dieter;
Reichert, Maximilian;
Schneider, Günter;
Wirth, Matthias

Publication type:

Article

The SUMO pathway in pancreatic cancer: insights and inhibition.

Published in:

2021

By:

Schneeweis, Christian;
Hassan, Zonera;
Schick, Markus;
Keller, Ulrich;
Schneider, Günter

Publication type:

journal article

Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil.

Published in:

EMBO Journal, 2001, v. 20, n. 4, p. 650, doi. 10.1093/emboj/20.4.650

By:

Dobritzsch, Doreen;
Schneider, Gunter;
Schnackerz, Klaus D.;
Lindqvist, Viva

Publication type:

Article

Crystal structure of ß-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of condensing enzymes.

Published in:

EMBO Journal, 1998, v. 17, n. 5, p. 1183, doi. 10.1093/emboj/17.5.1183

By:

Weijun Huang;
Jia, Jia;
Edwards, Patricia;
Dehesh, Katayoon;
Schneider, Gunter;
Lindqvist, Ylva

Publication type:

Article

Class 1 Histone Deacetylases and Ataxia-Telangiectasia Mutated Kinase Control the Survival of Murine Pancreatic Cancer Cells upon dNTP Depletion.

Published in:

Cells (2073-4409), 2021, v. 10, n. 10, p. 2520, doi. 10.3390/cells10102520

By:

Nguyen, Alexandra;
Dzulko, Melanie;
Murr, Janine;
Yen, Yun;
Schneider, Günter;
Krämer, Oliver H.

Publication type:

Article

TFIIA transcriptional activity is controlled by a 'cleave-and-run' Exportin-1/Taspase 1-switch.

Published in:

Journal of Molecular Cell Biology, 2018, v. 10, n. 1, p. 33, doi. 10.1093/jmcb/mjx025

By:

Schrenk, Christian;
Fetz, Verena;
Vallet, Cecilia;
Heiselmayer, Christina;
Schröder, Elisabeth;
Hensel, Astrid;
Hahlbrock, Angelina;
Wünsch, Désirée;
Goesswein, Dorothee;
Bier, Carolin;
Habtemichael, Negusse;
Schneider, Günter;
Stauber, Roland H.;
Knauer, Shirley K.

Publication type:

Article

Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stress.

Published in:

Journal of Molecular Cell Biology, 2012, v. 4, n. 5, p. 284, doi. 10.1093/jmcb/mjs013

By:

Brandl, André;
Wagner, Tobias;
Uhlig, Katharina M.;
Knauer, Shirley K.;
Stauber, Roland H.;
Melchior, Frauke;
Schneider, Günter;
Heinzel, Thorsten;
Krämer, Oliver H.

Publication type:

Article

Crystallization and preliminary X-ray diffraction study of 1,3,8-trihydroxynaphthalene reductase from Magnaporthe grisea.

Published in:

Proteins, 1996, v. 24, n. 4, p. 525, doi. 10.1002/(SICI)1097-0134(199604)24:4<525::AID-PROT14>3.0.CO;2-N

By:

Andersson, Arnold;
Jordan, Doug;
Schneider, Gunter;
Valent, Barbara;
Lindqvist, Ylva

Publication type:

Article

Electrostatic fields at the active site of ribulose-1,5-bisphosphate carboxylase.

Published in:

Proteins, 1992, v. 12, n. 2, p. 117, doi. 10.1002/prot.340120205

By:

Lu, Guoguang;
Lindqvist, Ylva;
Schneider, Gunter

Publication type:

Article

Crystal structure of the glycosyltransferase SnogD from the biosynthetic pathway of nogalamycin in Streptomyces nogalater.

Published in:

FEBS Journal, 2012, v. 279, n. 17, p. 3251, doi. 10.1111/j.1742-4658.2012.08711.x

By:

Claesson, Magnus;
Siitonen, Vilja;
Dobritzsch, Doreen;
Metsä-Ketelä, Mikko;
Schneider, Gunter

Publication type:

Article

Conservation of structure and mechanism within the transaldolase enzyme family.

Published in:

FEBS Journal, 2012, v. 279, n. 5, p. 766, doi. 10.1111/j.1742-4658.2011.08467.x

By:

Samland, Anne K.;
Baier, Shiromi;
Schürmann, Melanie;
Inoue, Tomoyuki;
Huf, Sabine;
Schneider, Gunter;
Sprenger, Georg A.;
Sandalova, Tatyana

Publication type:

Article

Effect of coenzyme modification on the structural and catalytic properties of wild-type transketolase and of the variant E418A fromSaccharomyces cerevisiae.

Published in:

FEBS Journal, 2005, v. 272, n. 6, p. 1326, doi. 10.1111/j.1742-4658.2005.04562.x

By:

Golbik, Ralph;
Meshalkina, Ludmilla E.;
Sandalova, Tatjana;
Tittmann, Kai;
Fiedler, Erik;
Neef, Holger;
König, Stephan;
Kluger, Ronald;
Kochetov, German A.;
Schneider, Gunter;
Hübner, Gerhard

Publication type:

Article

Identification of cytokeratin24 as a tumor suppressor for the management of head and neck cancer.

Published in:

Biological Chemistry, 2022, v. 403, n. 8/9, p. 869, doi. 10.1515/hsz-2021-0287

By:

Gül, Désirée;
Habtemichael, Negusse;
Dietrich, Dimo;
Dietrich, Jörn;
Gößwein, Dorothee;
Khamis, Aya;
Deuss, Eric;
Künzel, Julian;
Schneider, Günter;
Strieth, Sebastian;
Stauber, Roland H.

Publication type:

Article

Crystal structure of the flavoenzyme PA4991 from Pseudomonas aeruginosa.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2016, v. 72, n. 2, p. 105, doi. 10.1107/S2053230X15024437

By:

Jacewicz, Agata;
Schnell, Robert;
Lindqvist, Ylva;
Schneider, Gunter

Publication type:

Article

S-Selective Mixed Carboligation by Structure-Based Design of the Pyruvate Decarboxylase from Acetobacter pasteurianus.

Published in:

ChemCatChem, 2011, v. 3, n. 10, p. 1587, doi. 10.1002/cctc.201100054

By:

Rother (neé Gocke), Dörte;
Kolter, Geraldine;
Gerhards, Tina;
Berthold, Catrine L.;
Gauchenova, Ekaterina;
Knoll, Michael;
Pleiss, Jürgen;
Müller, Michael;
Schneider, Gunter;
Pohl, Martina

Publication type:

Article

Targeting histone deacetylases in pancreatic ductal adenocarcinoma.

Published in:

Journal of Cellular & Molecular Medicine, 2010, v. 14, n. 6a, p. 1255, doi. 10.1111/j.1582-4934.2009.00974.x

By:

Schneider, Günter;
Krämer, Oliver H.;
Fritsche, Petra;
Schüler, Susanne;
Schmid, Roland M.;
Saur, Dieter

Publication type:

Article

Inhibition of Wnt/β-Catenin Signaling Sensitizes Esophageal Cancer Cells to Chemoradiotherapy.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10301, doi. 10.3390/ijms221910301

By:

Spitzner, Melanie;
Emons, Georg;
Schütz, Karl Burkhard;
Wolff, Hendrik A.;
Rieken, Stefan;
Ghadimi, B. Michael;
Schneider, Günter;
Grade, Marian

Publication type:

Article

TRAIL/NF-κB/CX3CL1 Mediated Onco-Immuno Crosstalk Leading to TRAIL Resistance of Pancreatic Cancer Cell Lines.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 6, p. 1661, doi. 10.3390/ijms19061661

By:

Geismann, Claudia;
Erhart, Wiebke;
Grohmann, Frauke;
Schreiber, Stefan;
Schneider, Günter;
Schäfer, Heiner;
Arlt, Alexander

Publication type:

Article

The epigenetic modifier HDAC2 and the checkpoint kinase ATM determine the responses of microsatellite instable colorectal cancer cells to 5-fluorouracil.

Published in:

Cell Biology & Toxicology, 2023, v. 39, n. 5, p. 2401, doi. 10.1007/s10565-022-09731-3

By:

Kiweler, Nicole;
Schwarz, Helena;
Nguyen, Alexandra;
Matschos, Stephanie;
Mullins, Christina;
Piée-Staffa, Andrea;
Brachetti, Christina;
Roos, Wynand P.;
Schneider, Günter;
Linnebacher, Michael;
Brenner, Walburgis;
Krämer, Oliver H.

Publication type:

Article

The Importin-Alpha/Nucleophosmin Switch Controls Taspase1 Protease Function.

Published in:

Traffic, 2011, v. 12, n. 6, p. 703, doi. 10.1111/j.1600-0854.2011.01191.x

By:

Bier, Carolin;
Knauer, Shirley K.;
Docter, Dominic;
Schneider, Günter;
Krämer, Oliver H.;
Stauber, Roland H.

Publication type:

Article

Cannabidiol converts NF-κB into a tumor suppressor in glioblastoma with defined antioxidative properties.

Published in:

Neuro-Oncology, 2021, v. 23, n. 11, p. 1898, doi. 10.1093/neuonc/noab095

By:

Volmar, Marie N M;
Cheng, Jiying;
Alenezi, Haitham;
Richter, Sven;
Haug, Alisha;
Hassan, Zonera;
Goldberg, Maria;
Li, Yuping;
Hou, Mengzhuo;
Herold-Mende, Christel;
Maire, Cecile L;
Lamszus, Katrin;
Flüh, Charlotte;
Held-Feindt, Janka;
Gargiulo, Gaetano;
Topping, Geoffrey J;
Schilling, Franz;
Saur, Dieter;
Schneider, Günter;
Synowitz, Michael

Publication type:

Article

The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma.

Published in:

OncoImmunology, 2018, v. 7, n. 1, p. N.PAG, doi. 10.1080/2162402X.2017.1368603

By:

Lenk, Lennart;
Pein, Maren;
Will, Olga;
Gomez, Beatriz;
Viol, Fabrice;
Hauser, Charlotte;
Egberts, Jan-Hendrik;
Gundlach, Jan-Paul;
Helm, Ole;
Tiwari, Sanjay;
Weiskirchen, Ralf;
Rose-John, Stefan;
Röcken, Christoph;
Mikulits, Wolfgang;
Wenzel, Patrick;
Schneider, Günter;
Saur, Dieter;
Schäfer, Heiner;
Sebens, Susanne

Publication type:

Article

Analysis pipelines for cancer genome sequencing in mice.

Published in:

Nature Protocols, 2020, v. 15, n. 2, p. 266, doi. 10.1038/s41596-019-0234-7

By:

Lange, Sebastian;
Engleitner, Thomas;
Mueller, Sebastian;
Maresch, Roman;
Zwiebel, Maximilian;
González-Silva, Laura;
Schneider, Günter;
Banerjee, Ruby;
Yang, Fengtang;
Vassiliou, George S.;
Friedrich, Mathias J.;
Saur, Dieter;
Varela, Ignacio;
Rad, Roland

Publication type:

Article

Blocking the road to de‐differentiation: HNF1A/KDM6A complex safeguards epithelial integrity in pancreatic cancer.

Published in:

EMBO Journal, 2020, v. 39, n. 9, p. 1, doi. 10.15252/embj.2020104759

By:

Bärthel, Stefanie;
Schneider, Günter;
Saur, Dieter

Publication type:

Article

HDAC2 attenuates TRAIL-induced apoptosis of pancreatic cancer cells.

Published in:

Molecular Cancer, 2010, v. 9, p. 80, doi. 10.1186/1476-4598-9-80

By:

Schüler, Susanne;
Fritsche, Petra;
Diersch, Sandra;
Arlt, Alexander;
Schmid, Roland M.;
Saur, Dieter;
Schneider, Günter

Publication type:

Article

Apoptotic pathways in pancreatic ductal adenocarcinoma.

Published in:

Molecular Cancer, 2008, v. 7, p. 1, doi. 10.1186/1476-4598-7-64

By:

Hamacher, Rainer;
Schmid, Roland M.;
Saur, Dieter;
Schneider, Günter

Publication type:

Article

Genetic alterations in pancreatic carcinoma.

Published in:

Molecular Cancer, 2003, v. 2, p. 15, doi. 10.1186/1476-4598-2-15

By:

Schneider, Gunter;
Schmid, Roland M.

Publication type:

Article

Histone deacetylase inhibitors dysregulate DNA repair proteins and antagonize metastasis-associated processes.

Published in:

Journal of Cancer Research & Clinical Oncology, 2020, v. 146, n. 2, p. 343, doi. 10.1007/s00432-019-03118-4

By:

Kiweler, Nicole;
Wünsch, Désirée;
Wirth, Matthias;
Mahendrarajah, Nisintha;
Schneider, Günter;
Stauber, Roland H.;
Brenner, Walburgis;
Butter, Falk;
Krämer, Oliver H.

Publication type:

Article

IDENTIFICATION PROCESSES AMONG CHANGE AGENTS IN TECHNICAL SCHOOLS OF AFGHANISTAN.

Published in:

Journal of Social Psychology, 1972, v. 87, n. 1, p. 145, doi. 10.1080/00224545.1972.9918659

By:

Eckensberger, Lutz H.;
Schneider, Gunter F.

Publication type:

Article

Interstitial cells of Cajal plasticity rather than regeneration restores slow-wave activity and enteric neurotransmission upon acute damage.

Published in:

2013

By:

Klein, Sabine;
Seidler, Barbara;
Kettenberger, Anna;
Sibaev, Andrei;
Feil, Robert;
Hofmann, Franz;
Vanderwinden, Jean-Marie;
Allescher, Hans-Dieter;
Schemann, Michael;
Storr, Martin A.;
Schmid, Roland M.;
Schneider, Günter;
Saur, Dieter

Publication type:

Abstract

Interstitial cells of Cajal link excitatory and nitrergic inhibitory neurotransmission with slowwave activity in the intestine.

Published in:

2013

By:

Klein, Sabine;
Seidler, Barbara;
Kettenberger, Anna;
Sibaev, Andrei;
Rohn, Michael;
Feil, Robert;
Allescher, Hans-Dieter;
Vanderwinden, Jean-Marie;
Hofmann, Franz;
Schemann, Michael;
Rad, Roland;
Storr, Martin A.;
Schmid, Roland M.;
Schneider, Günter;
Saur, Dieter

Publication type:

Abstract

Induction of IκB-Kinase by Cholecystokinin Is Mediated by Trypsinogen Activation in Rat Pancreatic Lobules.

Published in:

Digestion, 2002, v. 66, n. 4, p. 237, doi. 10.1159/000068364

By:

Tando, Yusuke;
Algül, Hana;
Schneider, Günter;
Weber, Christoph K.;
Weidenbach, Hans;
Adler, Guido;
Schmid, Roland M.

Publication type:

Article

Inhibition of CDK4 impairs proliferation of pancreatic cancer cells and sensitizes towards TRAIL-induced apoptosis via downregulation of survivin.

Published in:

International Journal of Cancer, 2007, v. 121, n. 1, p. 66, doi. 10.1002/ijc.22619

By:

Retzer-Lidl, Michaela;
Schmid, Roland M.;
Schneider, Günter

Publication type:

Article

GADD45α is highly expressed in pancreatic ductal adenocarcinoma cells and required for tumor cell viability.

Published in:

International Journal of Cancer, 2006, v. 118, n. 10, p. 2405, doi. 10.1002/ijc.21637

By:

Schneider, Günter;
Weber, Andreas;
Zechner, Ulrich;
Oswald, Franz;
Friess, Helmut M.;
Schmid, Roland M.;
Liptay, Susanne

Publication type:

Article

NF-κB Dependent Chemokine Signaling in Pancreatic Cancer.

Published in:

Cancers, 2019, v. 11, n. 10, p. 1445, doi. 10.3390/cancers11101445

By:

Geismann, Claudia;
Schäfer, Heiner;
Gundlach, Jan-Paul;
Hauser, Charlotte;
Egberts, Jan-Hendrik;
Schneider, Günter;
Arlt, Alexander

Publication type:

Article

HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1.

Published in:

Cancers, 2019, v. 11, n. 10, p. 1436, doi. 10.3390/cancers11101436

By:

Beyer, Mandy;
Romanski, Annette;
Mustafa, Al-Hassan M.;
Pons, Miriam;
Büchler, Iris;
Vogel, Anja;
Pautz, Andrea;
Sellmer, Andreas;
Schneider, Günter;
Bug, Gesine;
Krämer, Oliver H.

Publication type:

Article

MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors.

Published in:

Cell Cycle, 2012, v. 11, n. 8, p. 1593, doi. 10.4161/cc.20008

By:

Labisso, Wajana L.;
Wirth, Matthias;
Stojanovic, Natasa;
Stauber, Roland H.;
Schnieke, Angelika;
Schmid, Roland M.;
Krämer, Oliver H.;
Saur, Dieter;
Schneider, Günter

Publication type:

Article

The polyketide cyclase RemF from Streptomyces resistomycificus contains an unusual octahedral zinc binding site

Published in:

FEBS Letters, 2009, v. 583, n. 17, p. 2917, doi. 10.1016/j.febslet.2009.07.061

By:

Silvennoinen, Laura;
Sandalova, Tatyana;
Schneider, Gunter

Publication type:

Article

The C-terminal of CysM from Mycobacterium tuberculosis protects the aminoacrylate intermediate and is involved in sulfur donor selectivity

Published in:

FEBS Letters, 2009, v. 583, n. 2, p. 330, doi. 10.1016/j.febslet.2008.12.019

By:

Ågren, Daniel;
Schnell, Robert;
Schneider, Gunter

Publication type:

Article

Crystal structure and reactivity of YbdL from Escherichia coli identify a methionine aminotransferase function

Published in:

FEBS Letters, 2004, v. 571, n. 1-3, p. 141, doi. 10.1016/j.febslet.2004.06.075

By:

Dolzan, Manuela;
Johansson, Kenth;
Roig-Zamboni, Véronique;
Campanacci, Valérie;
Tegoni, Mariella;
Schneider, Gunter;
Cambillau, Christian

Publication type:

Article

Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches.

Published in:

2019

By:

Orth, Michael;
Metzger, Philipp;
Gerum, Sabine;
Mayerle, Julia;
Schneider, Günter;
Belka, Claus;
Schnurr, Maximilian;
Lauber, Kirsten

Publication type:

journal article

Crystal structure analysis of a pentameric fungal and an icosahedral plant lumazine synthase reveals the structural basis for differences in assembly.

Published in:

Protein Science: A Publication of the Protein Society, 1999, v. 8, n. 11, p. 2355, doi. 10.1110/ps.8.11.2355

By:

Schneider, Gunter;
Sandalova, Tatyana;
Persson, Karina;
Jordan, Douglas B.;
Viitanen, Paul V.

Publication type:

Article

Crystal structure of two quaternary complexes of dethiobiotin synthetase, enzyme-MgADP-AlF<sub>3</sub>-diaminopelargonic acid and enzyme-MgADP-dethiobiotin-phosphate; implications for catalysis.

Published in:

Protein Science: A Publication of the Protein Society, 1998, v. 7, n. 12, p. 2560, doi. 10.1002/pro.5560071209

By:

Käck, Helena;
Sandmark, Jenny;
Schneider, Gunter;
Lindqvist, Ylva;
Gibson, Katharine J.

Publication type:

Article

Crystal structure of the reduced Schiff-base intermediate complex of transaldolase B from escherichia coli: Mechanistic implications for class I aldolases.

Published in:

Protein Science: A Publication of the Protein Society, 1997, v. 6, n. 1, p. 119, doi. 10.1002/pro.5560060113

By:

Jia, Jia;
Lindqvist, Ylva;
Schneider, Gunter;
Schörken, Ulrich;
Sprenger, Georg A.

Publication type:

Article

The structure of the N‐terminal module of the cell wall hydrolase RipA and its role in regulating catalytic activity.

Published in:

Proteins, 2018, v. 86, n. 9, p. 912, doi. 10.1002/prot.25523

By:

Steiner, Eva Maria;
Lyngsø, Jeppe;
Guy, Jodie E.;
Bourenkov, Gleb;
Lindqvist, Ylva;
Schneider, Thomas R.;
Pedersen, Jan Skov;
Schneider, Gunter;
Schnell, Robert

Publication type:

Article

Crystal structure of NirD, the small subunit of the nitrite reductase NirbD from Mycobacterium tuberculosis at 2.0 Å resolution.

Published in:

Proteins, 2012, v. 80, n. 12, p. 2799, doi. 10.1002/prot.24177

By:

Izumi, Atsushi;
Schnell, Robert;
Schneider, Gunter

Publication type:

Article

Identification of Late-Stage Glycosylation Steps in the Biosynthetic Pathway of the Anthracycline Nogalamycin.

Published in:

ChemBioChem, 2012, v. 13, n. 1, p. 120, doi. 10.1002/cbic.201100637

By:

Siitonen, Vilja;
Claesson, Magnus;
Patrikainen, Pekka;
Aromaa, Maria;
Mäntsälä, Pekka;
Schneider, Gunter;
Metsä-Ketelä, Mikko

Publication type:

Article

Redesigning the Active Site of Transaldolase TalB from Escherichia coli: New Variants with Improved Affinity towards Nonphosphorylated Substrates.

Published in:

ChemBioChem, 2010, v. 11, n. 5, p. 681, doi. 10.1002/cbic.200900720

By:

Schneider, Sarah;
Gutiérrez, Mariana;
Sandalova, Tatyana;
Schneider, Gunter;
Clapés, Pere;
Sprenger, Georg A.;
Samland, Anne K.

Publication type:

Article