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Enhanced Chondrogenic Differentiation Activities in Human Bone Marrow Aspirates via sox9 Overexpression Mediated by pNaSS-Grafted PCL Film-Guided rAAV Gene Transfer.
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- Pharmaceutics, 2020, v. 12, n. 3, p. 280, doi. 10.3390/pharmaceutics12030280
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- Publication type:
- Article
Effects of TGF-β Overexpression via rAAV Gene Transfer on the Early Repair Processes in an Osteochondral Defect Model in Minipigs.
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- American Journal of Sports Medicine, 2018, v. 46, n. 8, p. 1987, doi. 10.1177/0363546518773709
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- Publication type:
- Article
Therapeutic Effects of rAAV-Mediated Concomittant Gene Transfer and Overexpression of TGF-β and IGF-I on the Chondrogenesis of Human Bone-Marrow-Derived Mesenchymal Stem Cells.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 10, p. 2591, doi. 10.3390/ijms20102591
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- Article
Cytotoxic effects of different mouthwash solutions on primary human articular chondrocytes and normal human articular cartilage – an in vitro study.
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- Clinical Oral Investigations, 2023, v. 27, n. 9, p. 4987, doi. 10.1007/s00784-023-05118-8
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- Publication type:
- Article
Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment.
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- Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1637, doi. 10.3390/jcm8101637
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- Article
Remodeling of Human Osteochondral Defects via rAAV-Mediated Co-Overexpression of TGF-β and IGF-I from Implanted Human Bone Marrow-Derived Mesenchymal Stromal Cells.
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- Journal of Clinical Medicine, 2019, v. 8, n. 9, p. 1326, doi. 10.3390/jcm8091326
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- Article
Genetic Modification of Human Peripheral Blood Aspirates Using Recombinant Adeno-Associated Viral Vectors for Articular Cartilage Repair with a Focus on Chondrogenic Transforming Growth Factor-β Gene Delivery.
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- Stem Cells Translational Medicine, 2017, v. 6, n. 1, p. 249, doi. 10.5966/sctm.2016-0149
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- Publication type:
- Article
Influence of insulin-like growth factor Ioverexpression via recombinant adeno-associated or gene transfer upon the biological activities and differentiation potential of human bone marrow-derived mesenchymal stem cells.
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- Stem Cell Research & Therapy, 2014, v. 5, n. 4, p. 103, doi. 10.1186/scrt491
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- Publication type:
- Article
Locally Directed Recombinant Adeno- Associated Virus–Mediated IGF-1 Gene Therapy Enhances Osteochondral Repair and Counteracts Early Osteoarthritis In Vivo.
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- American Journal of Sports Medicine, 2024, v. 52, n. 5, p. 1336, doi. 10.1177/03635465241235149
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- Publication type:
- Article
rAAV-Mediated sox9 Overexpression Improves the Repair of Osteochondral Defects in a Clinically Relevant Large Animal Model Over Time In Vivo and Reduces Perifocal Osteoarthritic Changes.
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- American Journal of Sports Medicine, 2021, v. 49, n. 13, p. 3696, doi. 10.1177/03635465211049414
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- Publication type:
- Article
rAAV-Mediated Human FGF-2 Gene Therapy Enhances Osteochondral Repair in a Clinically Relevant Large Animal Model Over Time In Vivo.
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- American Journal of Sports Medicine, 2021, v. 49, n. 4, p. 958, doi. 10.1177/0363546521988941
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- Article
Differential Effects of Prenatal Stress in 5-Htt Deficient Mice: Towards Molecular Mechanisms of Gene 6 Environment Interactions.
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- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0022715
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- Publication type:
- Article
rAAV-mediated overexpression of TGF-ß via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model.
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- International Journal of Nanomedicine, 2017, v. 12, p. 6985, doi. 10.2147/IJN.S144579
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- Article
rAAV Vectors as Safe and Efficient Tools for the Stable Delivery of Genes to Primary Human Chondrosarcoma Cells In Vitro and In Situ.
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- 2012
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- Publication type:
- Journal Article
rAAV Vectors as Safe and Efficient Tools for the Stable Delivery of Genes to Primary Human Chondrosarcoma Cells In Vitro and In Situ.
- Published in:
- Sarcoma, 2012, p. 1, doi. 10.1155/2012/347417
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- Publication type:
- Article
rAAV-mediated combined gene transfer and overexpression of TGF-β and SOX9 remodels human osteoarthritic articular cartilage.
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- Journal of Orthopaedic Research, 2016, v. 34, n. 12, p. 2181, doi. 10.1002/jor.23228
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- Publication type:
- Article
Peripheral blood aspirates overexpressing IGF-I via rAAV gene transfer undergo enhanced chondrogenic differentiation processes.
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- Journal of Cellular & Molecular Medicine, 2017, v. 21, n. 11, p. 2748, doi. 10.1111/jcmm.13190
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- Publication type:
- Article
TGF-β gene transfer and overexpression via rAAV vectors stimulates chondrogenic events in human bone marrow aspirates.
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- Journal of Cellular & Molecular Medicine, 2016, v. 20, n. 3, p. 430, doi. 10.1111/jcmm.12774
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- Publication type:
- Article
rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ.
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- Journal of Translational Medicine, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1479-5876-11-211
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- Publication type:
- Article
rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ.
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- 2013
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- Publication type:
- journal article
Benefits of Recombinant Adeno-Associated Virus (rAAV)-Mediated Insulinlike Growth Factor I (IGF-I) Overexpression for the Long-Term Reconstruction of Human Osteoarthritic Cartilage by Modulation of the IGF-I Axis.
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- Molecular Medicine, 2012, v. 18, n. 3, p. 346, doi. 10.2119/molmed.2011.00371
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- Publication type:
- Article
Effective, safe nonviral gene transfer to preserve the chondrogenic differentiation potential of human mesenchymal stem cells.
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- Journal of Gene Medicine, 2012, v. 14, n. 7, p. 501, doi. 10.1002/jgm.2644
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- Publication type:
- Article
A Photopolymerizable Biocompatible Hyaluronic Acid Hydrogel Promotes Early Articular Cartilage Repair in a Minipig Model In Vivo.
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- Advanced Healthcare Materials, 2023, v. 12, n. 26, p. 1, doi. 10.1002/adhm.202300931
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- Publication type:
- Article
Co-overexpression of TGF-β and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells.
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- Stem Cell Research & Therapy, 2016, v. 7, p. 1, doi. 10.1186/s13287-016-0280-9
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- Publication type:
- Article
Effects of rAAV-Mediated Overexpression of sox9 and TGF-ß via Alginate Hydrogel-Guided Vector Delivery on the Chondroreparative Activities of Human Bone Marrow-Derived Mesenchymal Stromal Cells.
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- Journal of Tissue Engineering & Regenerative Medicine, 2023, p. 1, doi. 10.1155/2023/4495697
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- Publication type:
- Article
Axial alignment is a critical regulator of knee osteoarthritis.
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- Science Translational Medicine, 2022, v. 14, n. 629, p. 1, doi. 10.1126/scitranslmed.abn0179
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- Publication type:
- Article
Hydrogel‐Guided, rAAV‐Mediated IGF‐I Overexpression Enables Long‐Term Cartilage Repair and Protection against Perifocal Osteoarthritis in a Large‐Animal Full‐Thickness Chondral Defect Model at One Year In Vivo.
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- Advanced Materials, 2021, v. 33, n. 16, p. 1, doi. 10.1002/adma.202008451
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- Publication type:
- Article
Thermosensitive Hydrogel Based on PEO–PPO–PEO Poloxamers for a Controlled In Situ Release of Recombinant Adeno‐Associated Viral Vectors for Effective Gene Therapy of Cartilage Defects.
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- Advanced Materials, 2020, v. 32, n. 2, p. N.PAG, doi. 10.1002/adma.201906508
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- Publication type:
- Article
Impact of mechanical stimulation on the chondrogenic processes in human bone marrow aspirates modified to overexpress sox9 via rAAV vectors.
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- Journal of Experimental Orthopaedics, 2017, v. 4, n. 1, p. 1, doi. 10.1186/s40634-017-0097-1
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- Publication type:
- Article
Effects of combined rAAV-mediated TGF-β and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates.
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- Journal of Experimental Orthopaedics, 2017, v. 4, n. 1, p. 1, doi. 10.1186/s40634-017-0077-5
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- Publication type:
- Article
Effects of rAAV‐mediated FGF‐2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates.
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- Journal of Experimental Orthopaedics, 2016, v. 3, n. 1, p. 1, doi. 10.1186/s40634-016-0052-6
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- Publication type:
- Article
Effects of rAAV-mediated FGF-2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates.
- Published in:
- Journal of Experimental Orthopaedics, 2016, v. 3, n. 1, p. 1, doi. 10.1186/s40634-016-0052-6
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- Publication type:
- Article
rAAV-Mediated Overexpression of SOX9 and TGF-β via Carbon Dot-Guided Vector Delivery Enhances the Biological Activities in Human Bone Marrow-Derived Mesenchymal Stromal Cells.
- Published in:
- Nanomaterials (2079-4991), 2020, v. 10, n. 5, p. 855, doi. 10.3390/nano10050855
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- Publication type:
- Article