Works by Schmidt, Laura S.

Results: 30

Cover, Volume 42, Issue 5.

Published in:

Human Mutation, 2021, v. 42, n. 5, p. i, doi. 10.1002/humu.24209

By:

Vocke, Cathy D.;
Ricketts, Christopher J.;
Schmidt, Laura S.;
Ball, Mark W.;
Middelton, Lindsay A.;
Zbar, Berton;
Linehan, W. Marston

Publication type:

Article

Comprehensive characterization of Alu‐mediated breakpoints in germline VHL gene deletions and rearrangements in patients from 71 VHL families.

Published in:

Human Mutation, 2021, v. 42, n. 5, p. 520, doi. 10.1002/humu.24194

By:

Vocke, Cathy D.;
Ricketts, Christopher J.;
Schmidt, Laura S.;
Ball, Mark W.;
Middelton, Lindsay A.;
Zbar, Berton;
Linehan, W. Marston

Publication type:

Article

Random mutagenesis-PCR to introduce alterations into defined DNA sequences for validation of SNP and mutation detection methods.

Published in:

Human Mutation, 2001, v. 17, n. 3, p. 210, doi. 10.1002/humu.6

By:

Nickerson, Michael L.;
Warren, Michelle B.;
Zbar, Berton;
Schmidt, Laura S.

Publication type:

Article

Expression of Birt-Hogg-Dubé gene mRNA in normal and neoplastic human tissues.

Published in:

Modern Pathology, 2004, v. 17, n. 8, p. 998, doi. 10.1038/modpathol.3800152

By:

Warren, Michelle B.;
Torres-Cabala, Carlos A.;
Turner, Maria L.;
Merino, Maria J.;
Matrosova, Vera Y.;
Nickerson, Michael L.;
Ma, Wenbin;
Linehan, W. Marston;
Zbar, Berton;
Schmidt, Laura S.

Publication type:

Article

Inactivation of the FLCN Tumor Suppressor Gene Induces TFE3 Transcriptional Activity by Increasing Its Nuclear Localization.

Published in:

PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0015793

By:

Hong, Seung-Beom;
Oh, HyoungBin;
Valera, Vladimir A.;
Baba, Masaya;
Schmidt, Laura S.;
Linehan, W. Marston

Publication type:

Article

Deciphering von Hippel-Lindau (VHL/Vhl)-Associated Pancreatic Manifestations by Inactivating Vhl in Specific Pancreatic Cell Populations.

Published in:

PLoS ONE, 2009, v. 4, n. 4, p. 1, doi. 10.1371/journal.pone.0004897

By:

Shen, H.-C. Jennifer;
Adem, Asha;
Ylaya, Kris;
Wilson, Arianne;
Mei He;
Lorang, Dominique;
Hewitt, Stephen M.;
Pechhold, Klaus;
Harlan, David M.;
Lubensky, Irina A.;
Schmidt, Laura S.;
Linehan, W. Marston;
Libutti, Steven K.

Publication type:

Article

Hereditary Kidney Cancer.

Published in:

Cancer (0008543X), 2009, v. 115, n. 10, p. 2252, doi. 10.1002/cncr.24230

By:

Linehan, W. Marston;
Pinto, Peter A.;
Bratslavsky, Gennady;
Pfaffenroth, Elizabeth;
Merino, Maria;
Vocke, Cathy D.;
Toro, Jorge R.;
Bottaro, Donald;
Neckers, Len;
Schmidt, Laura S.;
Srinivasan, Ramaprasad

Publication type:

Article

Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN.

Published in:

JNCI: Journal of the National Cancer Institute, 2012, v. 104, n. 22, p. 1750, doi. 10.1093/jnci/djs418

By:

Hasumi, Hisashi;
Baba, Masaya;
Hasumi, Yukiko;
Huang, Ying;
Oh, Hyoungbin;
Hughes, Robert M.;
Klein, Mara E.;
Takikita, Shoichi;
Nagashima, Kunio;
Schmidt, Laura S.;
Linehan, W. Marston

Publication type:

Article

Cryptic splice mutation in the fumarate hydratase gene in patients with clinical manifestations of Hereditary Leiomyomatosis and Renal Cell Cancer.

Published in:

Human Molecular Genetics, 2023, v. 32, n. 22, p. 3135, doi. 10.1093/hmg/ddad131

By:

Crooks, Daniel R;
Cawthon, Geetha Mariah;
Fitzsimmons, Christina M;
Perez, Minervo;
Ricketts, Christopher J;
Vocke, Cathy D;
Yang, Ye;
Middelton, Lindsay;
Nielsen, Debbie;
Schmidt, Laura S;
Tandon, Mayank;
Merino, Maria J;
Ball, Mark W;
Meier, Jordan L;
Batista, Pedro J;
Linehan, William Marston

Publication type:

Article

Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 21, p. 5706, doi. 10.1093/hmg/ddu286

By:

Hasumi, Yukiko;
Baba, Masaya;
Hasumi, Hisashi;
Huang, Ying;
Lang, Martin;
Reindorf, Rachel;
Oh, Hyoung-bin;
Sciarretta, Sebastiano;
Nagashima, Kunio;
Haines, Diana C.;
Schneider, Michael D.;
Adelstein, Robert S.;
Schmidt, Laura S.;
Sadoshima, Junichi;
Marston Linehan, W.

Publication type:

Article

A diagnosis of Birt–Hogg–Dubé syndrome in individuals with Smith–Magenis syndrome: Recommendation for cancer screening.

Published in:

American Journal of Medical Genetics. Part A, 2023, v. 191, n. 2, p. 490, doi. 10.1002/ajmg.a.63049

By:

Vocke, Cathy D.;
Fleming, Leah R.;
Piskorski, Anna M.;
Amin, Ali;
Phornphutkul, Chanika;
de la Monte, Suzanne;
Vilboux, Thierry;
Duncan, Folami;
Pellegrino, Joan;
Braddock, Bonnie;
Middelton, Lindsay A.;
Schmidt, Laura S.;
Merino, Maria J.;
Cowen, Edward W.;
Introne, Wendy J.;
Linehan, W. Marston;
Smith, Ann C. M.

Publication type:

Article

Lung Cysts, Spontaneous Pneumothorax, and Genetic Associations in 89 Families with Birt-Hogg-Dubé Syndrome.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2007, v. 175, n. 10, p. 1044, doi. 10.1164/rccm.200610-1483OC

By:

Toro, Jorge R.;
Pautler, Stephen E.;
Stewart, Laveta;
Glenn, Gladys M.;
Weinreich, Michael;
Toure, Ousmane;
Ming-Hui Wei;
Schmidt, Laura S.;
Davis, Lewis;
Zbar, Berton;
Choyke, Peter;
Steinberg, Seth M.;
Nguyen, Dao M.;
Linehan, W. Marston

Publication type:

Article

Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide–chlorambucil conjugate.

Published in:

Cancer Science, 2022, v. 113, n. 7, p. 2352, doi. 10.1111/cas.15364

By:

Funasaki, Shintaro;
Mehanna, Sally;
Ma, Wenjuan;
Nishizawa, Hidekazu;
Kamikubo, Yasuhiko;
Sugiyama, Hiroshi;
Ikeda, Shuji;
Motoshima, Takanobu;
Hasumi, Hisashi;
Linehan, W. Marston;
Schmidt, Laura S.;
Ricketts, Chris;
Suda, Toshio;
Oike, Yuichi;
Kamba, Tomomi;
Baba, Masaya

Publication type:

Article

MicroRNA‐204‐5p: A novel candidate urinary biomarker of Xp11.2 translocation renal cell carcinoma.

Published in:

Cancer Science, 2019, v. 110, n. 6, p. 1897, doi. 10.1111/cas.14026

By:

Kurahashi, Ryoma;
Kadomatsu, Tsuyoshi;
Baba, Masaya;
Hara, Chiaki;
Itoh, Hitoshi;
Miyata, Keishi;
Endo, Motoyoshi;
Morinaga, Jun;
Terada, Kazutoyo;
Araki, Kimi;
Eto, Masatoshi;
Schmidt, Laura S.;
Kamba, Tomomi;
Linehan, W. Marston;
Oike, Yuichi

Publication type:

Article

Kidney-Targeted Birt-Hogg-Dubé Gene Inactivation in a Mouse Model: Erkl/2 and Akt-mTOR Activation, Cell Hyperproliferation, and Polycystic Kidneys.

Published in:

JNCI: Journal of the National Cancer Institute, 2008, v. 100, n. 2, p. 140, doi. 10.1093/jnci/djm288

By:

Baba, Masaya;
Furihata, Mutsuo;
Seung-Beom Hong;
Tessarollo, Lino;
Haines, Diana C.;
Southon, Eileen;
Patel, Vishal;
Igarashi, Peter;
Alvord, W. Gregory;
Leighty, Robert;
Yao, Masahiro;
Bernardo, Marcelino;
Ileva, Lilia;
Choyke, Peter;
Warren, Michelle B.;
Zbar, Berton;
Linehan, W. Marston;
Schmidt, Laura S.

Publication type:

Article

High Frequency of Somatic Frameshift BHD Gene Mutations in Birt-Hogg-Dubé-Associated Renal Tumors.

Published in:

JNCI: Journal of the National Cancer Institute, 2005, v. 97, n. 12, p. 931, doi. 10.1093/jnci/dji154

By:

Vocke, Cathy D.;
Youfeng Yang;
Pavlovich, Christian P.;
Schmidt, Laura S.;
Nickerson, Michael L.;
Torres-Cabala, Carlos A.;
Merino, Maria J.;
Walther, McClellan M.;
Zbar, Berton;
Linehan, W. Marston

Publication type:

Article

Hereditary leiomyomatosis and renal cell carcinoma.

Published in:

International Journal of Nephrology & Renovascular Disease, 2014, v. 7, p. 253, doi. 10.2147/IJNRD.S42097

By:

Schmidt, Laura S.;
Linehan, W. Marston

Publication type:

Article

A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog.

Published in:

Human Molecular Genetics, 2003, v. 12, n. 23, p. 3043, doi. 10.1093/hmg/ddg336

By:

Lingaas, Frode;
Comstock, Kenine E.;
Kirkness, Ewen F.;
Sørensen, Anita;
Aarskaug, Tone;
Hitte, Christophe;
Nickerson, Michael L.;
Moe, Lars;
Schmidt, Laura S.;
Thomas, Rachael;
Breen, Matthew;
Galibert, Francis;
Zbar, Berton;
Ostrander, Elaine A.

Publication type:

Article

Germline- and Somatic-Inactivating FLCN Variants in Parathyroid Cancer and Atypical Parathyroid Tumors.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2023, v. 108, n. 10, p. 2686, doi. 10.1210/clinem/dgad136

By:

Jha, Smita;
Welch, James;
Tora, Rana;
Lack, Justin;
Warner, Andrew;
del Rivero, Jaydira;
Sadowski, Samira M.;
Nilubol, Naris;
Schmidt, Laura S.;
Linehan, W. Marston;
Weinstein, Lee S.;
Simonds, William F.;
Agarwal, Sunita K.

Publication type:

Article

Tobacco smoking induces metabolic reprogramming of renal cell carcinoma.

Published in:

2021

By:

Reigle, James;
Secic, Dina;
Biesiada, Jacek;
Wetzel, Collin;
Shamsaei, Behrouz;
Chu, Johnson;
Yuanwei Zang;
Xiang Zhang;
Talbot, Nicholas J.;
Bischoff, Megan E.;
Yongzhen Zhang;
Thakar, Charuhas V.;
Gaitonde, Krishnanath;
Sidana, Abhinav;
Hai Bui;
Cunningham, John T.;
Qing Zhang;
Schmidt, Laura S.;
Linehan, W. Marston;
Medvedovic, Mario

Publication type:

journal article

Identification of intragenic deletions and duplication in the FLCN gene in Birt-Hogg-Dubé syndrome.

Published in:

Genes, Chromosomes & Cancer, 2011, v. 50, n. 6, p. 466, doi. 10.1002/gcc.20872

By:

Benhammou, Jihane N.;
Vocke, Cathy D.;
Santani, Avni;
Schmidt, Laura S.;
Baba, Masaya;
Seyama, Kuniaki;
Wu, Xiaolin;
Korolevich, Susana;
Nathanson, Katherine L.;
Stolle, Catherine A.;
Linehan, W. Marston

Publication type:

Article

Searching for the hereditary causes of renal-cell carcinoma.

Published in:

Nature Reviews Cancer, 2004, v. 4, n. 5, p. 381, doi. 10.1038/nrc1364

By:

Pavlovich, Christian P.;
Schmidt, Laura S.

Publication type:

Article

The Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variants.

Published in:

Oncogene, 2004, v. 23, n. 31, p. 5387, doi. 10.1038/sj.onc.1207691

By:

Berthou, Sylvie;
Aebersold, Daniel M.;
Schmidt, Laura S.;
Stroka, Deborah;
Heigl, Christine;
Streit, Bruno;
Stalder, Denise;
Gruber, Guenther;
Liang, Congxin;
Howlett, Anthony R.;
Candinas, Daniel;
Greiner, Richard H.;
Lipson, Kenneth E.;
Zimmer, Yitzhak

Publication type:

Article

The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding.

Published in:

Nature Communications, 2016, v. 7, n. 6, p. 12037, doi. 10.1038/ncomms12037

By:

Woodford, Mark R.;
Dunn, Diana M.;
Blanden, Adam R.;
Capriotti, Dante;
Loiselle, David;
Prodromou, Chrisostomos;
Panaretou, Barry;
Hughes, Philip F.;
Smith, Aaron;
Ackerman, Wendi;
Haystead, Timothy A.;
Loh, Stewart N.;
Bourboulia, Dimitra;
Schmidt, Laura S.;
Marston Linehan, W.;
Bratslavsky, Gennady;
Mollapour, Mehdi

Publication type:

Article

Tumor suppressor FLCN inhibits tumorigenesis of aFLCN-null renal cancer cell line and regulatesexpression of key molecules in TGF-β signaling.

Published in:

Molecular Cancer, 2010, v. 9, p. 160, doi. 10.1186/1476-4598-9-160

By:

Seung-Beom Hong;
HyoungBin Oh;
Valera, Vladimir A.;
Stull, Jaime;
Duy-Tan Ngo;
Baba, Masaya;
Merino, Maria J.;
Linehan, W. Marston;
Schmidt, Laura S.

Publication type:

Article

The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours.

Published in:

Nature, 2005, v. 435, n. 7040, p. 360, doi. 10.1038/nature03595

By:

Youngren, Kirsten K.;
Coveney, Douglas;
Xiaoning Peng;
Bhattacharya, Chitralekha;
Schmidt, Laura S.;
Nickerson, Michael L.;
Lamb, Bruce T.;
Jian Min Deng;
Behringer, Richard R.;
Capel, Blanche;
Rubin, Edward M.;
Nadeau, Joseph H.;
Matin, Angabin

Publication type:

Article

Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure.

Published in:

Stem Cells, 2016, v. 34, n. 4, p. 1068, doi. 10.1002/stem.2293

By:

Baba, Masaya;
Toyama, Hirofumi;
Sun, Lei;
Takubo, Keiyo;
Suh, Hyung-Chan;
Hasumi, Hisashi;
Nakamura-Ishizu, Ayako;
Hasumi, Yukiko;
Klarmann, Kimberly D.;
Nakagata, Naomi;
Schmidt, Laura S.;
Linehan, W. Marston;
Suda, Toshio;
Keller, Jonathan R.

Publication type:

Article

Signature-based analysis of MET proto-oncogene mutations using DHPLC.

Published in:

Human Mutation, 2000, v. 16, n. 1, p. 68, doi. 10.1002/1098-1004(200007)16:1<68::AID-HUMU12>3.0.CO;2-U

By:

Nickerson, Michael L.;
Weirich, Gregor;
Zbar, Berton;
Schmidt, Laura S.

Publication type:

Article

High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2023, v. 42, n. 1, p. 1, doi. 10.1186/s13046-023-02667-4

By:

Lang, Martin;
Schmidt, Laura S.;
Wilson, Kelli M.;
Ricketts, Christopher J.;
Sourbier, Carole;
Vocke, Cathy D.;
Wei, Darmood;
Crooks, Daniel R.;
Yang, Youfeng;
Gibbs, Benjamin K.;
Zhang, Xiaohu;
Klumpp-Thomas, Carleen;
Chen, Lu;
Guha, Rajarshi;
Ferrer, Marc;
McKnight, Crystal;
Itkin, Zina;
Wangsa, Darawalee;
Wangsa, Danny;
James, Amy

Publication type:

Article

Von Hippel-Lindau (VHL) Inactivation in Sporadic Clear Cell Renal Cancer: Associations with Germline VHL Polymorphisms and Etiologic Risk Factors.

Published in:

PLoS Genetics, 2011, v. 7, n. 10, p. 1, doi. 10.1371/journal.pgen.1002312

By:

Moore, Lee E.;
Nickerson, Michael L.;
Brennan, Paul;
Toro, Jorge R.;
Jaeger, Erich;
Rinsky, Jessica;
Han, Summer S.;
Zaridze, David;
Matveev, Vsevolod;
Janout, Vladimir;
Kollarova, Hellena;
Bencko, Vladimir;
Navratilova, Marie;
Szeszenia-Dabrowska, Neonilia;
Mates, Dana;
Schmidt, Laura S.;
Lenz, Petra;
Karami, Sara;
Linehan, W. Marston;
Merino, Maria

Publication type:

Article