Works by Schmidli, Heinz

Results: 57

Therapeutic drug monitoring for everolimus in kidney transplantation using 12-month exposure, efficacy, and safety data.

Published in:

Clinical Transplantation, 2005, v. 19, n. 2, p. 145, doi. 10.1111/j.1399-0012.2005.00326.x

By:

Lorber, Marc I.;
Ponticelli, Claudio;
Whelchel, John;
Mayer, Hartmut W.;
Kovarik, John;
Li, Yulan;
Schmidli, Heinz

Publication type:

Article

Beyond Randomized Clinical Trials: Use of External Controls.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 107, n. 4, p. 806, doi. 10.1002/cpt.1723

By:

Schmidli, Heinz;
Häring, Dieter A.;
Thomas, Marius;
Cassidy, Adrian;
Weber, Sebastian;
Bretz, Frank

Publication type:

Article

Identifying treatment effects using trimmed means when data are missing not at random.

Published in:

Pharmaceutical Statistics, 2021, v. 20, n. 6, p. 1265, doi. 10.1002/pst.2147

By:

Ocampo, Alex;
Schmidli, Heinz;
Quarg, Peter;
Callegari, Francesca;
Pagano, Marcello

Publication type:

Article

Principal stratum strategy: Potential role in drug development.

Published in:

Pharmaceutical Statistics, 2021, v. 20, n. 4, p. 737, doi. 10.1002/pst.2104

By:

Bornkamp, Björn;
Rufibach, Kaspar;
Lin, Jianchang;
Liu, Yi;
Mehrotra, Devan V.;
Roychoudhury, Satrajit;
Schmidli, Heinz;
Shentu, Yue;
Wolbers, Marcel

Publication type:

Article

Blinded sample size reestimation in event‐driven clinical trials: Methods and an application in multiple sclerosis.

Published in:

Pharmaceutical Statistics, 2019, v. 18, n. 3, p. 351, doi. 10.1002/pst.1927

By:

Friede, Tim;
Pohlmann, Harald;
Schmidli, Heinz

Publication type:

Article

Blinded continuous monitoring in clinical trials with recurrent event endpoints.

Published in:

Pharmaceutical Statistics, 2019, v. 18, n. 1, p. 54, doi. 10.1002/pst.1907

By:

Friede, Tim;
Häring, Dieter A.;
Schmidli, Heinz

Publication type:

Article

Sample size re‐estimation incorporating prior information on a nuisance parameter.

Published in:

Pharmaceutical Statistics, 2018, v. 17, n. 2, p. 126, doi. 10.1002/pst.1837

By:

Mütze, Tobias;
Schmidli, Heinz;
Friede, Tim

Publication type:

Article

A Bayesian hierarchical surrogate outcome model for multiple sclerosis.

Published in:

Pharmaceutical Statistics, 2016, v. 15, n. 4, p. 341, doi. 10.1002/pst.1749

By:

Pozzi, Luca;
Schmidli, Heinz;
Ohlssen, David I.

Publication type:

Article

Model averaging for treatment effect estimation in subgroups.

Published in:

Pharmaceutical Statistics, 2017, v. 16, n. 2, p. 133, doi. 10.1002/pst.1796

By:

Bornkamp, Björn;
Ohlssen, David;
Magnusson, Baldur P.;
Schmidli, Heinz

Publication type:

Article

A practical guide to Bayesian group sequential designs.

Published in:

Pharmaceutical Statistics, 2014, v. 13, n. 1, p. 71, doi. 10.1002/pst.1593

By:

Gsponer, Thomas;
Gerber, Florian;
Bornkamp, Björn;
Ohlssen, David;
Vandemeulebroecke, Marc;
Schmidli, Heinz

Publication type:

Article

Designing a non-inferiority study in kidney transplantation: a case study.

Published in:

Pharmaceutical Statistics, 2011, v. 10, n. 5, p. 427, doi. 10.1002/pst.511

By:

Witte, Steffen;
Schmidli, Heinz;
O'Hagan, Anthony;
Racine, Amy

Publication type:

Article

The impact of period effects on dose level contrasts in alternating cross-over designs for first-time-in-human studies.

Published in:

Pharmaceutical Statistics, 2011, v. 10, n. 1, p. 45, doi. 10.1002/pst.409

By:

Koehne-Voss, Stephan;
Schmidli, Heinz;
Smith, David M.;
Pigeot, Iris

Publication type:

Article

QUANTIFICATION OF BATCH HOMOGENEITY.

Published in:

Quality Engineering, 1997, v. 10, n. 2, p. 359, doi. 10.1080/08982119708919143

By:

Schmidli, Heinz;
Grize, Yves-L.

Publication type:

Article

Time-patterns of annualized relapse rates in randomized placebo-controlled clinical trials in relapsing multiple sclerosis: A systematic review and meta-analysis.

Published in:

Multiple Sclerosis Journal, 2012, v. 18, n. 9, p. 1290, doi. 10.1177/1352458511435715

By:

Nicholas, Richard;
Straube, Sebastian;
Schmidli, Heinz;
Pfeiffer, Sebastian;
Friede, Tim

Publication type:

Article

Trends in annualized relapse rates in relapsing–remitting multiple sclerosis and consequences for clinical trial design.

Published in:

Multiple Sclerosis Journal, 2011, v. 17, n. 10, p. 1211, doi. 10.1177/1352458511406309

By:

Nicholas, Richard;
Straube, Sebastian;
Schmidli, Heinz;
Schneider, Simon;
Friede, Tim

Publication type:

Article

Evidence synthesis from aggregate recurrent event data for clinical trial design and analysis.

Published in:

Statistics in Medicine, 2018, v. 37, n. 6, p. 867, doi. 10.1002/sim.7549

By:

Holzhauer, Björn;
Wang, Craig;
Schmidli, Heinz

Publication type:

Article

Evidence synthesis from aggregate recurrent event data for clinical trial design and analysis.

Published in:

2017

By:

Holzhauer, Björn;
Wang, Craig;
Schmidli, Heinz

Publication type:

journal article

Analysis of clinical trials with biologics using dose-time-response models.

Published in:

Statistics in Medicine, 2015, v. 34, n. 22, p. 3017, doi. 10.1002/sim.6551

By:

Lange, Markus R.;
Schmidli, Heinz

Publication type:

Article

Optimal design of clinical trials with biologics using dose-time-response models.

Published in:

Statistics in Medicine, 2014, v. 33, n. 30, p. 5249, doi. 10.1002/sim.6299

By:

Lange, Markus R.;
Schmidli, Heinz

Publication type:

Article

Robustness of methods for blinded sample size re-estimation with overdispersed count data.

Published in:

Statistics in Medicine, 2013, v. 32, n. 21, p. 3623, doi. 10.1002/sim.5800

By:

Schneider, Simon;
Schmidli, Heinz;
Friede, Tim

Publication type:

Article

Using historical control information for the design and analysis of clinical trials with overdispersed count data.

Published in:

Statistics in Medicine, 2013, v. 32, n. 21, p. 3609, doi. 10.1002/sim.5851

By:

Gsteiger, Sandro;
Neuenschwander, Beat;
Mercier, Francois;
Schmidli, Heinz

Publication type:

Article

Blinded sample size reestimation with count data: Methods and applications in multiple sclerosis.

Published in:

Statistics in Medicine, 2010, v. 29, n. 10, p. 1145, doi. 10.1002/sim.3861

By:

Friede, Tim;
Schmidli, Heinz

Publication type:

Article

Group sequential designs with robust semiparametric recurrent event models.

Published in:

2019

By:

Mütze, Tobias;
Glimm, Ekkehard;
Schmidli, Heinz;
Friede, Tim

Publication type:

journal article

Group sequential designs for negative binomial outcomes.

Published in:

2019

By:

Mütze, Tobias;
Glimm, Ekkehard;
Schmidli, Heinz;
Friede, Tim

Publication type:

journal article

Modelling and sample size reestimation for longitudinal count data with incomplete follow up.

Published in:

2019

By:

Asendorf, Thomas;
Henderson, Robin;
Schmidli, Heinz;
Friede, Tim

Publication type:

journal article

The network meta-analytic-predictive approach to non-inferiority trials.

Published in:

Statistical Methods in Medical Research, 2013, v. 22, n. 2, p. 219, doi. 10.1177/0962280211432512

By:

Schmidli, Heinz;
Wandel, Simon;
Neuenschwander, Beat

Publication type:

Article

Bayesian predictive power for interim adaptation in seamless phase II/III trials where the endpoint is survival up to some specified timepoint.

Published in:

Statistics in Medicine, 2007, v. 26, n. 27, p. 4925, doi. 10.1002/sim.2957

By:

Schmidli, Heinz;
Bretz, Frank;
Racine-Poon, Amy

Publication type:

Article

Estimating time-varying effects for overdispersed recurrent events data with treatment switching.

Published in:

Biometrika, 2013, v. 100, n. 2, p. 339, doi. 10.1093/biomet/ass091

By:

Chen, Qingxia;
Zeng, Donglin;
Ibrahim, Joseph G.;
Akacha, Mouna;
Schmidli, Heinz

Publication type:

Article

Application of Artificial Neural Networks (ANN) in the Development of Solid Dosage Forms.

Published in:

Pharmaceutical Development & Technology, 1997, v. 2, n. 2, p. 111, doi. 10.3109/10837459709022616

By:

Bourquin, Jacques;
Schmidli, Heinz;
van Hoogevest, Peter;
Leuenberger, Hans

Publication type:

Article

Basic Concepts of Artificial Neural Networks (ANN) Modeling in the Application to Pharmaceutical Development.

Published in:

Pharmaceutical Development & Technology, 1997, v. 2, n. 2, p. 95, doi. 10.3109/10837459709022615

By:

Bourquin, Jacques;
Schmidli, Heinz;
van Hoogevest, Peter;
Leuenberger, Hans

Publication type:

Article

Rivastigmine exposure provided by a transdermal patch versus capsules.

Published in:

Current Medical Research & Opinion, 2007, v. 23, n. 12, p. 3199, doi. 10.1185/030079908X253438

By:

François Mercier;
Gilbert Lefèvre;
Hsun-Lun Aaron Huang;
Heinz Schmidli;
Billy Amzal;
Silke Appel-Dingemanse

Publication type:

Article

Improving pediatric multiple sclerosis interventional phase III study design: a meta-analysis.

Published in:

Therapeutic Advances in Neurological Disorders, 2022, p. 1, doi. 10.1177/17562864211070449

By:

Graves, Jennifer S.;
Thomas, Marius;
Li, Jun;
Shah, Anuja R.;
Goodyear, Alexandra;
Lange, Markus R.;
Schmidli, Heinz;
Häring, Dieter A.;
Friede, Tim;
Gärtner, Jutta

Publication type:

Article

Improving pediatric multiple sclerosis interventional phase III study design: a meta-analysis.

Published in:

Therapeutic Advances in Neurological Disorders, 2022, v. 15, p. 1, doi. 10.1177/17562864211070449

By:

Graves, Jennifer S.;
Thomas, Marius;
Jun Li;
Shah, Anuja R.;
Goodyear, Alexandra;
Lange, Markus R.;
Schmidli, Heinz;
Häring, Dieter A.;
Friede, Tim;
Gärtner, Jutta

Publication type:

Article

Incorporating historical information in biosimilar trials: Challenges and a hybrid Bayesian‐frequentist approach.

Published in:

Biometrical Journal, 2018, v. 60, n. 3, p. 564, doi. 10.1002/bimj.201700152

By:

Mielke, Johanna;
Schmidli, Heinz;
Jones, Byron

Publication type:

Article

Blinded and unblinded internal pilot study designs for clinical trials with count data.

Published in:

Biometrical Journal, 2013, v. 55, n. 4, p. 617, doi. 10.1002/bimj.201200189

By:

Schneider, Simon;
Schmidli, Heinz;
Friede, Tim

Publication type:

Article

Bayesian methods for the design and analysis of noninferiority trials.

Published in:

Journal of Biopharmaceutical Statistics, 2016, v. 26, n. 5, p. 823, doi. 10.1080/10543406.2015.1074920

By:

Gamalo-Siebers, Margaret;
Gao, Aijun;
Lakshminarayanan, Mani;
Liu, Guanghan;
Natanegara, Fanni;
Railkar, Radha;
Schmidli, Heinz;
Song, Guochen

Publication type:

Article

Overdispersion Models in SAS.

Published in:

2013

By:

Schmidli, Heinz

Publication type:

Book Review

Pharmacokinetics and electrocardiographic pharmacodynamics of artemether-lumefantrine (Riamet<sup>®</sup> ) with concomitant administration of ketoconazole in healthy subjects.

Published in:

British Journal of Clinical Pharmacology, 2002, v. 54, n. 5, p. 485, doi. 10.1046/j.1365-2125.2002.01696.x

By:

Lefèvre, Gilbert;
Carpenter, Polly;
Souppart, Claire;
Schmidli, Heinz;
McClean, Mark;
Stypinski, Daria

Publication type:

Article

Interaction Trial between Artemether-Lumefantrine (Riamet®) and Quinine in Healthy Subjects.

Published in:

Journal of Clinical Pharmacology, 2002, v. 42, n. 10, p. 1147, doi. 10.1177/009127002237995

By:

Lefèvre, Gilbert;
Carpenter, Polly;
Souppart, Claire;
Schmidli, Heinz;
Martin, John M.;
Lane, Andrew;
Ward, Chris;
Amakye, Dereck

Publication type:

Article

Bayesian inference for a principal stratum estimand on recurrent events truncated by death.

Published in:

Biometrics, 2023, v. 79, n. 4, p. 3792, doi. 10.1111/biom.13831

By:

Lyu, Tianmeng;
Bornkamp, Björn;
Mueller‐Velten, Guenther;
Schmidli, Heinz

Publication type:

Article

Predictively consistent prior effective sample sizes.

Published in:

Biometrics, 2020, v. 76, n. 2, p. 578, doi. 10.1111/biom.13252

By:

Neuenschwander, Beat;
Weber, Sebastian;
Schmidli, Heinz;
O'Hagan, Anthony

Publication type:

Article

Rejoinder to "Predictively consistent prior effective sample sizes," by Beat Neuenschwander, Sebastian Weber, Heinz Schmidli, and Anthony O'Hagan.

Published in:

Biometrics, 2020, v. 76, n. 2, p. 602, doi. 10.1111/biom.13245

By:

Neuenschwander, Beat;
Weber, Sebastian;
Schmidli, Heinz;
O'Hagan, Anthony

Publication type:

Article

Robust meta-analytic-predictive priors in clinical trials with historical control information.

Published in:

Biometrics, 2014, v. 70, n. 4, p. 1023, doi. 10.1111/biom.12242

By:

Schmidli, Heinz;
Gsteiger, Sandro;
Roychoudhury, Satrajit;
O'Hagan, Anthony;
Spiegelhalter, David;
Neuenschwander, Beat

Publication type:

Article

Discussions.

Published in:

Biometrics, 2012, v. 68, n. 1, p. 212, doi. 10.1111/j.1541-0420.2011.01624.x

By:

Schmidli, Heinz;
Neuenschwander, Beat

Publication type:

Article

Estimands—What they are and why they are important for pharmacometricians.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 279, doi. 10.1002/psp4.12617

By:

Akacha, Mouna;
Bartels, Christian;
Bornkamp, Björn;
Bretz, Frank;
Coello, Neva;
Dumortier, Thomas;
Looby, Michael;
Sander, Oliver;
Schmidli, Heinz;
Steimer, Jean‐Louis;
Vong, Camille

Publication type:

Article

Low Systemic Absorption and Good Tolerability of Pimecrolimus, Administered as 1% Cream (Elidel®) in Infants with Atopic Dermatitis – A Multicenter, 3-Week, Open-Label Study.

Published in:

Pediatric Dermatology, 2005, v. 22, n. 5, p. 465, doi. 10.1111/j.1525-1470.2005.00128.x

By:

Staab, Doris;
Pariser, David;
Gottlieb, Alice B.;
Kaufmann, Roland;
Eichenfield, Laurence F.;
Langley, Richard G.;
Scott, Graham;
Ebelin, Marie-Eve;
Barilla, Denise;
Schmidli, Heinz;
Burtin, Pascale

Publication type:

Article

Blinded continuous information monitoring of recurrent event endpoints with time trends in clinical trials.

Published in:

Statistics in Medicine, 2020, v. 39, n. 27, p. 3968, doi. 10.1002/sim.8702

By:

Mütze, Tobias;
Salem, Susanna;
Benda, Norbert;
Schmidli, Heinz;
Friede, Tim

Publication type:

Article

Bayesian inference for a principal stratum estimand to assess the treatment effect in a subgroup characterized by postrandomization event occurrence.

Published in:

2019

By:

Magnusson, Baldur P.;
Schmidli, Heinz;
Rouyrre, Nicolas;
Scharfstein, Daniel O.

Publication type:

journal article

Sample size re-estimation for clinical trials with longitudinal negative binomial counts including time trends.

Published in:

2019

By:

Asendorf, Thomas;
Henderson, Robin;
Schmidli, Heinz;
Friede, Tim

Publication type:

journal article

Rejoinder.

Published in:

Biometrical Journal, 2006, v. 48, n. 4, p. 660

By:

Frank Bretz;
Heinz Schmidli;
Franz König;
Amy Racine;
Willi Maurer

Publication type:

Article