Works matching AU Schlee, Martin

Results: 28

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 7, p. 781, doi. 10.1038/nsmb.1863

By:

Yanli Wang;
Ludwig, Janos;
Schuberth, Christine;
Goldeck, Marion;
Schlee, Martin;
Haitao Li;
Juranek, Stefan;
Sheng, Gang;
Micura, Ronald;
Tuschl, Thomas;
Hartmann, Gunther;
Patel, Dinshaw J.

Publication type:

Article

Human TLR8 Senses RNA From Plasmodium falciparum -Infected Red Blood Cells Which Is Uniquely Required for the IFN-γ Response in NK Cells.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00371

By:

Coch, Christoph;
Hommertgen, Benjamin;
Zillinger, Thomas;
Daßler-Plenker, Juliane;
Putschli, Bastian;
Nastaly, Maximilian;
Kümmerer, Beate M.;
Scheunemann, Johanna F.;
Schumak, Beatrix;
Specht, Sabine;
Schlee, Martin;
Barchet, Winfried;
Hoerauf, Achim;
Bartok, Eva;
Hartmann, Gunther

Publication type:

Article

Sequence-specific potent induction of IFN-aby short interfering RNA in plasmacytoid dendritic cells through TLR7.

Published in:

Nature Medicine, 2005, v. 11, n. 3, p. 263, doi. 10.1038/nm1191

By:

Hornung, Veit;
Guenthner-Biller, Margit;
Bourquin, Carole;
Ablasser, Andrea;
Schlee, Martin;
Uematsu, Satoshi;
Noronha, Anne;
Manoharan, Muthiah;
Akira, Shizuo;
de Fougerolles, Antonin;
Endres, Stefan;
Hartmann, Gunther

Publication type:

Article

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production.

Published in:

Nature Immunology, 2010, v. 11, n. 1, p. 63, doi. 10.1038/ni.1824

By:

Poeck, Hendrik;
Bscheider, Michael;
Gross, Olaf;
Finger, Katrin;
Roth, Susanne;
Rebsamen, Manuele;
Hannesschläger, Nicole;
Schlee, Martin;
Rothenfusser, Simon;
Barchet, Winfried;
Kato, Hiroki;
Akira, Shizuo;
Inoue, Satoshi;
Endres, Stefan;
Peschel, Christian;
Hartmann, Gunther;
Hornung, Veit;
Ruland, Jürgen

Publication type:

Article

Mammalian WDR12 is a novel member of the Pes1—Bop1 complex and is required for ribosome biogenesis and cell proliferation.

Published in:

Journal of Cell Biology, 2005, v. 170, n. 3, p. 367, doi. 10.1083/jcb.200501141

By:

Höizel, Michael;
Rohrmoser, Michaela;
Schlee, Martin;
Grimm, Thomas;
Harasim, Thomas;
Malamoussi, Anastassia;
Gruber-Eber, Anita;
Kremmer, Elisabeth;
Hiddemann, Wolfgang;
Bornkamm, Georg W.;
Eick, Dirk

Publication type:

Article

Author Correction: An epigenetic GPI anchor defect impairs TLR4 signaling in the B cell transdifferentiation model for primary human monocytes BLaER1.

Published in:

2021

By:

Wegner, Julia;
Zillinger, Thomas;
Schlee-Guimaraes, Thais Marina;
Bartok, Eva;
Schlee, Martin

Publication type:

Correction Notice

An epigenetic GPI anchor defect impairs TLR4 signaling in the B cell transdifferentiation model for primary human monocytes BLaER1.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-94386-z

By:

Wegner, Julia;
Zillinger, Thomas;
Schlee-Guimaraes, Thais;
Bartok, Eva;
Schlee, Martin

Publication type:

Article

A Human <i>In Vitro</i> Whole Blood Assay to Predict the Systemic Cytokine Response to Therapeutic Oligonucleotides Including siRNA.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0071057

By:

Coch, Christoph;
Lück, Christian;
Schwickart, Anna;
Putschli, Bastian;
Renn, Marcel;
Höller, Tobias;
Barchet, Winfried;
Hartmann, Gunther;
Schlee, Martin

Publication type:

Article

RIG-I Detects Triphosphorylated RNA of <i>Listeria monocytogenes</i> during Infection in Non-Immune Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0062872

By:

Hagmann, Cristina Amparo;
Herzner, Anna Maria;
Abdullah, Zeinab;
Zillinger, Thomas;
Jakobs, Christopher;
Schuberth, Christine;
Coch, Christoph;
Higgins, Paul G.;
Wisplinghoff, Hilmar;
Barchet, Winfried;
Hornung, Veit;
Hartmann, Gunther;
Schlee, Martin

Publication type:

Article

Immunoengineering of a Photocaged 5´‐triphosphate Oligoribonucleotide Ligand for Spatiotemporal Control of RIG‐I Activation in Cancer.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 21, p. 1, doi. 10.1002/anie.202423321

By:

Lewash, Sandra Anika;
McKenney, Vivien Rose;
Wuebben, Christine;
Ludwig, Janos;
Hosni, Racha;
Radzey, Dirk;
Toma, Marieta I.;
Bartok, Eva;
Schlee, Martin;
Zillinger, Thomas;
Heckel, Alexander;
Hartmann, Gunther

Publication type:

Article

Cytosolic nucleic acid sensing as driver of critical illness: mechanisms and advances in therapy.

Published in:

Signal Transduction & Targeted Therapy, 2025, v. 10, n. 1, p. 1, doi. 10.1038/s41392-025-02174-2

By:

Chen, Zhaorong;
Behrendt, Rayk;
Wild, Lennart;
Schlee, Martin;
Bode, Christian

Publication type:

Article

G-rich DNA-induced stress response blocks type-I-IFN but not CXCL10 secretion in monocytes.

Published in:

Scientific Reports, 2016, p. 38405, doi. 10.1038/srep38405

By:

Herzner, Anna-Maria;
Wolter, Steven;
Zillinger, Thomas;
Schmitz, Saskia;
Barchet, Winfried;
Hartmann, Gunther;
Bartok, Eva;
Schlee, Martin

Publication type:

Article

c-MYC activation impairs the NF-κB and the interferon response: Implications for the pathogenesis of Burkitt's lymphoma.

Published in:

International Journal of Cancer, 2007, v. 120, n. 7, p. 1387, doi. 10.1002/ijc.22372

By:

Schlee, Martin;
Hölzel, Michael;
Bernard, Sandra;
Mailhammer, Reinhard;
Schuhmacher, Marino;
Reschke, Judith;
Eick, Dirk;
Marinkovic, Dragan;
Wirth, Thomas;
Rosenwald, Andreas;
Staudt, Louis M.;
Eilers, Martin;
Baran-Marszak, Fanny;
Fagard, Remi;
Feuillard, Jean;
Laux, Gerhard;
Bornkamm, Georg W.

Publication type:

Article

SiRNA delivery with exosome nanoparticles.

Published in:

Nature Biotechnology, 2011, v. 29, n. 4, p. 325, doi. 10.1038/nbt.1830

By:

van den Boorn, Jasper G.;
Schlee, Martin;
Coch, Christoph;
Hartmann, Gunther

Publication type:

Article

Immunoengineering eines Photocage‐geschützten 5′‐Triphosphat‐Oligoribonukleotid‐Liganden zur spatiotemporalen Kontrolle der RIG‐I‐Aktivierung bei Tumoren.

Published in:

Angewandte Chemie, 2025, v. 137, n. 21, p. 1, doi. 10.1002/ange.202423321

By:

Lewash, Sandra Anika;
McKenney, Vivien Rose;
Wuebben, Christine;
Ludwig, Janos;
Hosni, Racha;
Radzey, Dirk;
Toma, Marieta I.;
Bartok, Eva;
Schlee, Martin;
Zillinger, Thomas;
Heckel, Alexander;
Hartmann, Gunther

Publication type:

Article

RIG-I immunotherapy overcomes radioresistance in p53-positive malignant melanoma.

Published in:

Journal of Molecular Cell Biology, 2023, v. 15, n. 1, p. 1, doi. 10.1093/jmcb/mjad001

By:

Lambing, Silke;
Tan, Yu Pan;
Vasileiadou, Paraskevi;
Holdenrieder, Stefan;
Müller, Patrick;
Hagen, Christian;
Garbe, Stephan;
Behrendt, Rayk;
Schlee, Martin;
Boorn, Jasper G van den;
Bartok, Eva;
Renn, Marcel;
Hartmann, Gunther

Publication type:

Article

2'-O-methyltransferase-deficient yellow fever virus: Restricted replication in the midgut and secondary tissues of Aedes aegypti mosquitoes severely limits dissemination.

Published in:

PLoS Pathogens, 2024, v. 20, n. 10, p. 1, doi. 10.1371/journal.ppat.1012607

By:

vom Hemdt, Anja;
Thienel, Alexandra L.;
Ciupka, Katrin;
Wieseler, Janett;
Proksch, Hannah M.;
Schlee, Martin;
Kümmerer, Beate M.

Publication type:

Article

The Chase for the RIG-I Ligand—Recent Advances.

Published in:

Molecular Therapy, 2010, v. 18, n. 7, p. 1254, doi. 10.1038/mt.2010.90

By:

Schlee, Martin;
Hartmann, Gunther

Publication type:

Article

siRNA and isRNA: Two Edges of One Sword.

Published in:

Molecular Therapy, 2006, v. 14, n. 4, p. 463, doi. 10.1016/j.ymthe.2006.06.001

By:

Schlee, Martin;
Hornung, Veit;
Hartmann, Gunther

Publication type:

Article

Approaching the RNA ligand for RIG-I?

Published in:

Immunological Reviews, 2009, v. 227, n. 1, p. 66, doi. 10.1111/j.1600-065X.2008.00724.x

By:

Schlee, Martin;
Hartmann, Evelyn;
Coch, Christoph;
Wimmenauer, Vera;
Janke, Markus;
Barchet, Winfried;
Hartmann, Gunther

Publication type:

Article

Addendum: Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production.

Published in:

Nature Immunology, 2014, v. 15, n. 1, p. 109, doi. 10.1038/ni0114-109a

By:

Poeck, Hendrik;
Bscheider, Michael;
Gross, Olaf;
Finger, Katrin;
Roth, Susanne;
Rebsamen, Manuele;
Hannesschläger, Nicole;
Schlee, Martin;
Rothenfusser, Simon;
Barchet, Winfried;
Kato, Hiroki;
Akira, Shizuo;
Inoue, Satoshi;
Endres, Stefan;
Peschel, Christian;
Hartmann, Gunther;
Hornung, Veit;
Ruland, Jürgen

Publication type:

Article

Influenza A Infection Stimulates RIG-I and Enhances Effector Function of Primary Human NK Cells.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 15, p. 12220, doi. 10.3390/ijms241512220

By:

Mohamed, Adham Abuelola;
Soler, Sofía;
Wegner, Julia;
Bartok, Eva;
Stankovic, Sanda;
Brooks, Andrew G.;
Schlee, Martin

Publication type:

Article

Increased IKKЄ protein stability ensures efficient type I interferon responses in conditions of TBK1 deficiency.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1073608

By:

Wegner, Julia;
Hunkler, Charlotte;
Ciupka, Katrin;
Hartmann, Gunther;
Schlee, Martin

Publication type:

Article

Chronic endoplasmic reticulum stress in myotonic dystrophy type 2 promotes autoimmunity via mitochondrial DNA release.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45535-1

By:

Rösing, Sarah;
Ullrich, Fabian;
Meisterfeld, Susann;
Schmidt, Franziska;
Mlitzko, Laura;
Croon, Marijana;
Nattrass, Ryan G;
Eberl, Nadia;
Mahlberg, Julia;
Schlee, Martin;
Wieland, Anja;
Simon, Philipp;
Hilbig, Daniel;
Reuner, Ulrike;
Rapp, Alexander;
Bremser, Julia;
Mirtschink, Peter;
Drukewitz, Stephan;
Zillinger, Thomas;
Beissert, Stefan

Publication type:

Article

Targeting the Cytosolic Innate Immune Receptors RIG-I and MDA5 Effectively Counteracts Cancer Cell Heterogeneity in Glioblastoma.

Published in:

Stem Cells, 2013, v. 31, n. 6, p. 1064, doi. 10.1002/stem.1350

By:

Glas, Martin;
Coch, Christoph;
Trageser, Daniel;
Daßler, Juliane;
Simon, Matthias;
Koch, Philipp;
Mertens, Jerome;
Quandel, Tamara;
Gorris, Raphaela;
Reinartz, Roman;
Wieland, Anja;
Von Lehe, Marec;
Pusch, Annette;
Roy, Kristin;
Schlee, Martin;
Neumann, Harald;
Fimmers, Rolf;
Herrlinger, Ulrich;
Brüstle, Oliver;
Hartmann, Gunther

Publication type:

Article

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates.

Published in:

Nature, 2014, v. 514, n. 7522, p. 372, doi. 10.1038/nature13590

By:

Goubau, Delphine;
Schlee, Martin;
Deddouche, Safia;
Rehwinkel, Jan;
Pruijssers, Andrea J.;
Iskarpatyoti, Jason A.;
Zillinger, Thomas;
Goldeck, Marion;
Schuberth, Christine;
Barchet, Winfried;
Ludwig, Janos;
Hartmann, Gunther;
Van der Veen, Annemarthe G.;
Reis e Sousa, Caetano;
Fujimura, Tsutomu;
Dermody, Terence S.

Publication type:

Article

Stringent doxycycline-dependent control of gene activities using an episomal one-vector system.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 16, p. e137, doi. 10.1093/nar/gni137

By:

Bornkamm, Georg W.;
Berens, Christian;
Kuklik-Roos, Conny;
Bechet, Jean-Marie;
Laux, Gerhard;
Bachl, Jürgen;
Korndoerfer, Martin;
Schlee, Martin;
Hölzel, Michael;
Malamoussi, Anastassia;
Chapman, Rob D.;
Nimmerjahn, Falk;
Mautner, Josef;
Hillen, Wolfgang;
Bujard, Hermann;
Feuillard, Jean

Publication type:

Article

RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids.

Published in:

EMBO Journal, 2012, v. 31, n. 21, p. 4153, doi. 10.1038/emboj.2012.274

By:

Abdullah, Zeinab;
Schlee, Martin;
Roth, Susanne;
Mraheil, Mobarak Abu;
Barchet, Winfried;
Böttcher, Jan;
Hain, Torsten;
Geiger, Sergej;
Hayakawa, Yoshihiro;
Fritz, Jörg H;
Civril, Filiz;
Hopfner, Karl-Peter;
Kurts, Christian;
Ruland, Jürgen;
Hartmann, Gunther;
Chakraborty, Trinad;
Knolle, Percy A

Publication type:

Article