Found: 48
Select item for more details and to access through your institution.
Collinearity of protease mutations in HIV-1 samples with high-level protease inhibitor class resistance.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2013, v. 68, n. 2, p. 414, doi. 10.1093/jac/dks409
- By:
- Publication type:
- Article
Structural and molecular analysis of a protective epitope of Lyme disease antigen OspA and antibody interactions.
- Published in:
- Journal of Molecular Recognition, 2017, v. 30, n. 5, p. n/a, doi. 10.1002/jmr.2595
- By:
- Publication type:
- Article
Structure of the catalytically active APOBEC3G bound to a DNA oligonucleotide inhibitor reveals tetrahedral geometry of the transition state.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34752-1
- By:
- Publication type:
- Article
Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31210-w
- By:
- Publication type:
- Article
Toward the Design of Mutation-Resistant Enzyme Inhibitors: Further Evaluation of the Substrate Envelope Hypothesis.
- Published in:
- Chemical Biology & Drug Design, 2009, v. 74, n. 3, p. 234, doi. 10.1111/j.1747-0285.2009.00851.x
- By:
- Publication type:
- Article
Analyses of HIV proteases variants at the threshold of viability reveals relationships between processing efficiency and fitness.
- Published in:
- Virus Evolution, 2021, v. 7, n. 2, p. 1, doi. 10.1093/ve/veab103
- By:
- Publication type:
- Article
Synthesis and Biological Evaluation of 4/5‐Aroyl‐2‐aminoimidazoles as Microbial Biofilm Inhibitors.
- Published in:
- ChemistrySelect, 2020, v. 5, n. 20, p. 5965, doi. 10.1002/slct.202001302
- By:
- Publication type:
- Article
Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants.
- Published in:
- Frontiers in Immunology, 2022, v. 12, p. 1, doi. 10.3389/fimmu.2022.995412
- By:
- Publication type:
- Article
A call to arms: Unifying the fight against resistance.
- Published in:
- 2018
- By:
- Publication type:
- Editorial
Design of Mutation-resistant HIV Protease Inhibitors with the Substrate Envelope Hypothesis.
- Published in:
- Chemical Biology & Drug Design, 2007, v. 69, n. 5, p. 298, doi. 10.1111/j.1747-0285.2007.00514.x
- By:
- Publication type:
- Article
Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G.
- Published in:
- Nature Structural & Molecular Biology, 2015, v. 22, n. 6, p. 485, doi. 10.1038/nsmb.3033
- By:
- Publication type:
- Article
Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5.
- Published in:
- Nature Structural & Molecular Biology, 2008, v. 15, n. 11, p. 1213, doi. 10.1038/nsmb.1496
- By:
- Publication type:
- Article
Point mutants of EHEC intimin that diminish Tir recognition and actin pedestal formation highlight a putative Tir binding pocket.
- Published in:
- Molecular Microbiology, 2002, v. 45, n. 6, p. 1557, doi. 10.1046/j.1365-2958.2002.03137.x
- By:
- Publication type:
- Article
Modulation of HIV protease flexibility by the T80N mutation.
- Published in:
- Proteins, 2015, v. 83, n. 11, p. 1929, doi. 10.1002/prot.24737
- By:
- Publication type:
- Article
Computational design and experimental study of tighter binding peptides to an inactivated mutant of HIV-1 protease.
- Published in:
- Proteins, 2008, v. 70, n. 3, p. 678, doi. 10.1002/prot.21514
- By:
- Publication type:
- Article
Mass spectrometry analysis of HIV-1 Vif reveals an increase in ordered structure upon oligomerization in regions necessary for viral infectivity.
- Published in:
- Proteins, 2007, v. 69, n. 2, p. 270, doi. 10.1002/prot.21471
- By:
- Publication type:
- Article
Evaluation of the substrate envelope hypothesis for inhibitors of HIV-1 protease.
- Published in:
- Proteins, 2007, v. 68, n. 2, p. 561, doi. 10.1002/prot.21431
- By:
- Publication type:
- Article
Substrate specificity in HIV-1 protease by a biased sequence search method.
- Published in:
- Proteins, 2006, v. 64, n. 2, p. 444, doi. 10.1002/prot.21023
- By:
- Publication type:
- Article
Cooperative fluctuations of unliganded and substrate-bound HIV-1 protease: A structure-based analysis on a variety of conformations from crystallography and molecular dynamics simulations.
- Published in:
- Proteins, 2003, v. 51, n. 3, p. 409, doi. 10.1002/prot.10350
- By:
- Publication type:
- Article
Accessibility and order of water sites in and around proteins: A crystallographic time-averaging study.
- Published in:
- Proteins, 1999, v. 36, n. 4, p. 501, doi. 10.1002/(SICI)1097-0134(19990901)36:4<501::AID-PROT14>3.0.CO;2-1
- By:
- Publication type:
- Article
NMR and MD studies combined to elucidate inhibitor and water interactions of HIV-1 protease and their modulations with resistance mutations.
- Published in:
- Journal of Biomolecular NMR, 2019, v. 73, n. 6/7, p. 365, doi. 10.1007/s10858-019-00260-6
- By:
- Publication type:
- Article
Quantitative comparison of errors in N transverse relaxation rates measured using various CPMG phasing schemes.
- Published in:
- Journal of Biomolecular NMR, 2012, v. 53, n. 1, p. 13, doi. 10.1007/s10858-012-9621-x
- By:
- Publication type:
- Article
PTEN enters the nucleus by diffusion.
- Published in:
- Journal of Cellular Biochemistry, 2005, v. 96, n. 2, p. 221, doi. 10.1002/jcb.20525
- By:
- Publication type:
- Article
Comprehensive fitness landscape of SARS-CoV-2 M<sup>pro</sup> reveals insights into viral resistance mechanisms.
- Published in:
- eLife, 2022, p. 1, doi. 10.7554/eLife.77433
- By:
- Publication type:
- Article
Constrained Mutational Sampling of Amino Acids in HIV-1 Protease Evolution.
- Published in:
- Molecular Biology & Evolution, 2019, v. 36, n. 4, p. 798, doi. 10.1093/molbev/msz022
- By:
- Publication type:
- Article
Positive Selection Drives Preferred Segment Combinations during Influenza Virus Reassortment.
- Published in:
- Molecular Biology & Evolution, 2015, v. 32, n. 6, p. 1519, doi. 10.1093/molbev/msv044
- By:
- Publication type:
- Article
Structural stability of disulfide mutants of basic pancreatic trypsin inhibitor: A molecular dynamics study.
- Published in:
- Proteins, 1996, v. 26, n. 1, p. 66, doi. 10.1002/(SICI)1097-0134(199609)26:1<66::AID-PROT6>3.0.CO;2-E
- By:
- Publication type:
- Article
Prediction of homologous protein structures based on conformational searches and energetics.
- Published in:
- Proteins, 1990, v. 8, n. 1, p. 30, doi. 10.1002/prot.340080107
- By:
- Publication type:
- Article
Inhibition of APOBEC3G activity impedes double-stranded DNA repair.
- Published in:
- FEBS Journal, 2016, v. 283, n. 1, p. 112, doi. 10.1111/febs.13556
- By:
- Publication type:
- Article
Citrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα.
- Published in:
- Science Immunology, 2017, v. 2, n. 12, p. 1, doi. 10.1126/sciimmunol.aal3062
- By:
- Publication type:
- Article
Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.
- Published in:
- Nature Communications, 2017, v. 8, n. 4, p. 15024, doi. 10.1038/ncomms15024
- By:
- Publication type:
- Article
Elucidating the Substrate Envelope of Enterovirus 68-3C Protease: Structural Basis of Specificity and Potential Resistance.
- Published in:
- Viruses (1999-4915), 2024, v. 16, n. 9, p. 1419, doi. 10.3390/v16091419
- By:
- Publication type:
- Article
Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses.
- Published in:
- Viruses (1999-4915), 2023, v. 15, n. 3, p. 781, doi. 10.3390/v15030781
- By:
- Publication type:
- Article
Crystal Structure of SARS-CoV-2 Main Protease in Complex with the Non-Covalent Inhibitor ML188.
- Published in:
- Viruses (1999-4915), 2021, v. 13, n. 2, p. 174, doi. 10.3390/v13020174
- By:
- Publication type:
- Article
The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors.
- Published in:
- PLoS Pathogens, 2012, v. 8, n. 7, p. 1, doi. 10.1371/journal.ppat.1002832
- By:
- Publication type:
- Article
Optimizing the refinement of merohedrally twinned P6<sub>1</sub> HIV‐1 protease–inhibitor cocrystal structures.
- Published in:
- Acta Crystallographica: Section D, Structural Biology, 2020, v. 76, n. 3, p. 302, doi. 10.1107/S2059798320001989
- By:
- Publication type:
- Article
Selection of HIV-1 for resistance to fifthgeneration protease inhibitors reveals two independent pathways to highlevel resistance.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.80328
- By:
- Publication type:
- Article
Mechanism for APOBEC3G catalytic exclusion of RNA and non-substrate DNA.
- Published in:
- Nucleic Acids Research, 2019, v. 47, n. 14, p. 7676, doi. 10.1093/nar/gkz550
- By:
- Publication type:
- Article
Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA.
- Published in:
- Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-04872-8
- By:
- Publication type:
- Article
Drug-resistant HIV-1 protease regains functional dynamics through cleavage site coevolution.
- Published in:
- Evolutionary Applications, 2015, v. 8, n. 2, p. 185, doi. 10.1111/eva.12241
- By:
- Publication type:
- Article
Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design.
- Published in:
- FEBS Letters, 2014, v. 588, n. 9, p. 1743, doi. 10.1016/j.febslet.2014.03.026
- By:
- Publication type:
- Article
Influenza Virus Drug Resistance: A Time-Sampled Population Genetics Perspective.
- Published in:
- PLoS Genetics, 2014, v. 10, n. 2, p. 1, doi. 10.1371/journal.pgen.1004185
- By:
- Publication type:
- Article
Molecular Basis for Drug Resistance in HIV-1 Protease.
- Published in:
- Viruses (1999-4915), 2010, v. 2, n. 11, p. 2509, doi. 10.3390/v2112509
- By:
- Publication type:
- Article
Structural, kinetic, and thermodynamic studies of specificity designed HIV-1 protease.
- Published in:
- Protein Science: A Publication of the Protein Society, 2012, v. 21, n. 7, p. 1029, doi. 10.1002/pro.2086
- By:
- Publication type:
- Article
Lack of synergy for inhibitors targeting a multi-drug-resistant HIV-1 protease.
- Published in:
- Protein Science: A Publication of the Protein Society, 2002, v. 11, n. 2, p. 418, doi. 10.1110/ps.25502
- By:
- Publication type:
- Article
Unique structural solution from a VH3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20879-6
- By:
- Publication type:
- Article
APOBEC3s: DNA‐editing human cytidine deaminases.
- Published in:
- Protein Science: A Publication of the Protein Society, 2019, v. 28, n. 9, p. 1552, doi. 10.1002/pro.3670
- By:
- Publication type:
- Article
The interdomain interface in bifunctional enzyme protein 3/4A (NS3/4A) regulates protease and helicase activities.
- Published in:
- Protein Science: A Publication of the Protein Society, 2013, v. 22, n. 12, p. 1786, doi. 10.1002/pro.2378
- By:
- Publication type:
- Article