Works by Schiöth, Helgi B.

Results: 252

Trends in the exploitation of novel drug targets.

Published in:

2011

By:

Rask-Andersen, Mathias;
Almén, Markus Sällman;
Schiöth, Helgi B.;
Almén, Markus Sällman;
Schiöth, Helgi B

Publication type:

journal article

Corrigendum: Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties.

Published in:

2025

By:

Muslim, Wisam Taher;
Mohammad, Layth Jasim;
Naji, Munaf M.;
Karimi, Isaac;
Al-Sabti, Matheel D.;
Jabir, Majid;
Najm, Mazin A. A.;
Schiöth, Helgi B.

Publication type:

Correction Notice

Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1511627

By:

Muslim, Wisam Taher;
Mohammad, Layth Jasim;
Naji, Munaf M.;
Karimi, Isaac;
Al-Sabti, Matheel D.;
Jabir, Majid;
Najm, Mazin A. A.;
Schiöth, Helgi B.

Publication type:

Article

Dissecting signaling and functions of adhesion G protein-coupled receptors.

Published in:

Annals of the New York Academy of Sciences, 2013, v. 1276, n. 1, p. 1, doi. 10.1111/j.1749-6632.2012.06820.x

By:

Araç, Demet;
Aust, Gabriela;
Calebiro, Davide;
Engel, Felix B.;
Formstone, Caroline;
Goffinet, André;
Hamann, Jörg;
Kittel, Robert J.;
Liebscher, Ines;
Lin, Hsi‐Hsien;
Monk, Kelly R.;
Petrenko, Alexander;
Piao, Xianhua;
Prömel, Simone;
Schiöth, Helgi B.;
Schwartz, Thue W.;
Stacey, Martin;
Ushkaryov, Yuri A.;
Wobus, Manja;
Wolfrum, Uwe

Publication type:

Article

MC<sub>3</sub> receptors are involved in the protective effect of melanocortins in myocardial ischemia/reperfusion-induced arrhythmias.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2002, v. 366, n. 2, p. 177, doi. 10.1007/s00210-002-0572-8

By:

Guarini, Salvatore;
Schiöth, Helgi B.;
Mioni, Chiara;
Cainazzo, Maria;
Ferrazza, Giuseppe;
Giuliani, Daniela;
Wikberg, Jarl E. S.;
Bertolini, Alfio;
Bazzani, Carla

Publication type:

Article

Comprehensive overview of the toxicities of small-molecule cryoprotectants for carnivorous spermatozoa: foundation for computational cryobiotechnology.

Published in:

Frontiers in Toxicology, 2025, p. 1, doi. 10.3389/ftox.2025.1477822

By:

Karimi, Isaac;
Mohammad, Layth Jasim;
Suvitha, A.;
Haidari, Zohreh;
Schiöth, Helgi B.

Publication type:

Article

Synaptic changes induced by melanocortin signalling.

Published in:

Nature Reviews Neuroscience, 2014, v. 15, n. 2, p. 98, doi. 10.1038/nrn3657

By:

Caruso, Vanni;
Lagerström, Malin C.;
Olszewski, Pawel K.;
Fredriksson, Robert;
Schiöth, Helgi B.

Publication type:

Article

Corrigendum: Recent advances in gold nanostructure-based biosensors in detecting diabetes biomarkers.

Published in:

2025

By:

Jamshidnejad-Tosaramandani, Tahereh;
Kashanian, Soheila;
Omidfar, Kobra;
Schiöth, Helgi B.

Publication type:

Correction Notice

Recent advances in gold nanostructure-based biosensors in detecting diabetes biomarkers.

Published in:

Frontiers in Bioengineering & Biotechnology, 2025, p. 1, doi. 10.3389/fbioe.2024.1446355

By:

Jamshidnejad-Tosaramandani, Tahereh;
Kashanian, Soheila;
Omidfar, Kobra;
Schiöth, Helgi B.

Publication type:

Article

Growth Hormone-Releasing Hormone Improves Cognitive Function in Older Adults: Sleep On It.

Published in:

JAMA Neurology, 2013, v. 70, n. 4, p. 529, doi. 10.1001/2013.jamaneurol.349

By:

Benedict, Christian;
Chapman, Colin D.;
Schiöth, Helgi B.

Publication type:

Article

Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-53446-w

By:

Al-Sabri, Mohamed H.;
Ammar, Nourhane;
Korzh, Stanislava;
Alsehli, Ahmed M.;
Hosseini, Kimia;
Fredriksson, Robert;
Mwinyi, Jessica;
Williams, Michael J.;
Boukhatmi, Hadi;
Schiöth, Helgi B.

Publication type:

Article

The international clinical trials registry platform (ICTRP): data integrity and the trends in clinical trials, diseases, and drugs.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1228148

By:

Namiot, Eugenia D.;
Smirnovová, Diana;
Sokolov, Aleksandr V.;
Chubarev, Vladimir N.;
Tarasov, Vadim V.;
Schiöth, Helgi B.

Publication type:

Article

Synthesis of an insulin-loaded mucoadhesive nanoparticle designed for intranasal administration: focus on new diffusion media.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1227423

By:

Jamshidnejad-Tosaramandani, Tahereh;
Kashanian, Soheila;
Karimi, Isaac;
Schiöth, Helgi B.

Publication type:

Article

Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43485-8

By:

Mälarstig, Anders;
Grassmann, Felix;
Dahl, Leo;
Dimitriou, Marios;
McLeod, Dianna;
Gabrielson, Marike;
Smith-Byrne, Karl;
Thomas, Cecilia E.;
Huang, Tzu-Hsuan;
Forsberg, Simon K. G.;
Eriksson, Per;
Ulfstedt, Mikael;
Johansson, Mattias;
Sokolov, Aleksandr V.;
Schiöth, Helgi B.;
Hall, Per;
Schwenk, Jochen M.;
Czene, Kamila;
Hedman, Åsa K.

Publication type:

Article

Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies.

Published in:

Frontiers in Aging Neuroscience, 2016, p. 1, doi. 10.3389/fnagi.2016.00180

By:

Williams, Michael J.;
Perland, Emelie;
Eriksson, Mikaela M.;
Carlsson, Josef;
Erlandsson, Daniel;
Laan, Loora;
Mahebali, Tabusi;
Potter, Ella;
Frediksson, Robert;
Benedict, Christian;
Schiöth, Helgi B.;
Gerstner, Jason Robert;
Junhai Han

Publication type:

Article

Job satisfaction and job tenure of people with mental health disorders: a UK Biobank cohort study.

Published in:

Scandinavian Journal of Public Health, 2023, v. 51, n. 8, p. 1248, doi. 10.1177/14034948221119639

By:

Mohammad, Salahuddin;
Miguet, Maud;
Rukh, Gull;
Schiöth, Helgi B.;
Mwinyi, Jessica

Publication type:

Article

Perceived stress is related to lower blood pressure in a Swedish cohort.

Published in:

Scandinavian Journal of Public Health, 2023, v. 51, n. 4, p. 611, doi. 10.1177/14034948211030352

By:

Miguet, Maud;
Olivo, Gaia;
Ciuculete, Diana-Maria;
Elmståhl, Sölve;
Lind, Lars;
Schiöth, Helgi B.

Publication type:

Article

Neoantigen Vaccines; Clinical Trials, Classes, Indications, Adjuvants and Combinatorial Treatments.

Published in:

Cancers, 2022, v. 14, n. 20, p. 5163, doi. 10.3390/cancers14205163

By:

Niemi, Jenni Viivi Linnea;
Sokolov, Aleksandr V.;
Schiöth, Helgi B.

Publication type:

Article

Kiwi genome provides insights into evolution of a nocturnal lifestyle.

Published in:

Genome Biology, 2015, v. 16, n. 1, p. 147, doi. 10.1186/s13059-015-0711-4

By:

Le Duc, Diana;
Renaud, Gabriel;
Krishnan, Arunkumar;
Almén, Markus Sällman;
Huynen, Leon;
Prohaska, Sonja J.;
Ongyerth, Matthias;
Bitarello, Bárbara D.;
Schiöth, Helgi B.;
Hofreiter, Michael;
Stadler, Peter F.;
Prüfer, Kay;
Lambert, David;
Kelso, Janet;
Schöneberg, Torsten

Publication type:

Article

Anorexia nervosa is linked to reduced brain structure in reward and somatosensory regions: a meta-analysis of VBM studies.

Published in:

BMC Psychiatry, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-244X-13-110

By:

Titova, Olga E.;
Hjorth, Olof C.;
Schiöth, Helgi B.;
Brooks, Samantha J.

Publication type:

Article

Assessing volumetric brain differences in migraine and depression patients: a UK Biobank study.

Published in:

BMC Neurology, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12883-023-03336-x

By:

Affatato, Oreste;
Dahlén, Amelia D.;
Rukh, Gull;
Schiöth, Helgi B.;
Mwinyi, Jessica

Publication type:

Article

A simple high-throughput method for automated detection of Drosophila melanogaster light-dependent behaviours.

Published in:

BMC Biology, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12915-022-01476-z

By:

Moulin, Thiago C.;
Dey, Sovik;
Dashi, Giovanna;
Li, Lei;
Sridhar, Vaasudevan;
Safa, Tania;
Berkins, Samuel;
Williams, Michael J.;
Schiöth, Helgi B.

Publication type:

Article

A pharmacogenetic risk score for the evaluation of major depression severity under treatment with antidepressants.

Published in:

Drug Development Research, 2020, v. 81, n. 1, p. 102, doi. 10.1002/ddr.21609

By:

Kanders, Sofia H.;
Pisanu, Claudia;
Bandstein, Marcus;
Jonsson, Jörgen;
Castelao, Enrique;
Pistis, Giorgio;
Gholam‐Rezaee, Mehdi;
Eap, Chin B.;
Preisig, Martin;
Schiöth, Helgi B.;
Mwinyi, Jessica

Publication type:

Article

Enhanced Toxicity of Bisphenols Together with UV Filters in Water: Identification of Synergy and Antagonism in Three-Component Mixtures.

Published in:

Molecules, 2022, v. 27, n. 10, p. 3260, doi. 10.3390/molecules27103260

By:

Kudłak, Błażej;
Jatkowska, Natalia;
Liu, Wen;
Williams, Michael J.;
Barcelo, Damia;
Schiöth, Helgi B.

Publication type:

Article

Artificial Neural Network (ANN)-Based Pattern Recognition Approach Illustrates a Biphasic Behavioral Effect of Ethanol in Zebrafish: A High-Throughput Method for Animal Locomotor Analysis.

Published in:

Biomedicines, 2023, v. 11, n. 12, p. 3215, doi. 10.3390/biomedicines11123215

By:

Myrov, Vladislav O.;
Polovian, Aleksandr I.;
Kolchanova, Sofiia;
Galumov, Georgii K.;
Schiöth, Helgi B.;
Bozhko, Dmitrii V.

Publication type:

Article

Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4.

Published in:

Biomedicines, 2023, v. 11, n. 11, p. 3032, doi. 10.3390/biomedicines11113032

By:

Lagunas-Rangel, Francisco Alejandro;
Liao, Sifang;
Williams, Michael J.;
Trukhan, Vladimir;
Fredriksson, Robert;
Schiöth, Helgi B.

Publication type:

Article

Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis.

Published in:

Biomedicines, 2023, v. 11, n. 1, p. 192, doi. 10.3390/biomedicines11010192

By:

Moulin, Thiago C.;
Stojanovic, Tijana;
Rajesh, Rasika P.;
Pareek, Tirusha;
Donzelli, Laura;
Williams, Michael J.;
Schiöth, Helgi B.

Publication type:

Article

Generation of Endogenous Promoter-Driven Luciferase Reporter System Using CRISPR/Cas9 for Investigating Transcriptional Regulation of the Core Clock Gene BMAL1.

Published in:

Biomedicines, 2022, v. 10, n. 12, p. 3108, doi. 10.3390/biomedicines10123108

By:

Sun, Chengxi;
Li, Chen;
Liu, Wen;
Schiöth, Helgi B.

Publication type:

Article

Efficacy of combination therapy with GABA, a DPP-4i and a PPI as an adjunct to insulin therapy in patients with type 1 diabetes.

Published in:

Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1171886

By:

Rabinovitch, Alexander;
Koshelev, Daniil;
Lagunas-Rangel, Francisco Alejandro;
Kosheleva, Liudmila;
Gavra, Tali;
Schiöth, Helgi B.;
Levit, Shmuel

Publication type:

Article

A deep learning model for brain age prediction using minimally preprocessed T1w images as input.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2023.1303036

By:

Dartora, Caroline;
Marseglia, Anna;
Mårtensson, Gustav;
Rukh, Gull;
Dang, Junhua;
Muehlboeck, J.-Sebastian;
Wahlund, Lars-Olof;
Moreno, Rodrigo;
Barroso, José;
Ferreira, Daniel;
Schiöth, Helgi B.;
Westman, Eric

Publication type:

Article

A genetic variant in proximity to the gene LYPLAL1 is associated with lower hunger feelings and increased weight loss following Roux-en-Y gastric bypass surgery.

Published in:

Scandinavian Journal of Gastroenterology, 2016, v. 51, n. 9, p. 1050, doi. 10.3109/00365521.2016.1166519

By:

Bandstein, Marcus;
Mwinyi, Jessica;
Ernst, Barbara;
Thurnheer, Martin;
Schultes, Bernd;
Schiöth, Helgi B.

Publication type:

Article

Insulin receptor-like ectodomain genes and splice variants are found in both arthropods and human brain cDNA.

Published in:

Journal of Systematics & Evolution, 2013, v. 51, n. 6, p. 664, doi. 10.1111/jse.12048

By:

VÄSTERMARK, Åke;
RASK‐ANDERSEN, Mathias;
SAWANT, Rahul S.;
REITER, Jill L.;
SCHIÖTH, Helgi B.;
WILLIAMS, Michael J.

Publication type:

Article

meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes.

Published in:

Clinical Epigenetics, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13148-020-00884-8

By:

Ciuculete, Diana M.;
Voisin, Sarah;
Kular, Lara;
Jonsson, Jörgen;
Rask-Andersen, Mathias;
Mwinyi, Jessica;
Schiöth, Helgi B.

Publication type:

Article

Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals.

Published in:

Clinical Epigenetics, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13148-018-0593-x

By:

Elbere, Ilze;
Silamikelis, Ivars;
Ustinova, Monta;
Kalnina, Ineta;
Zaharenko, Linda;
Peculis, Raitis;
Konrade, Ilze;
Ciuculete, Diana Maria;
Zhukovsky, Christina;
Gudra, Dita;
Radovica-Spalvina, Ilze;
Fridmanis, Davids;
Pirags, Valdis;
Schiöth, Helgi B.;
Klovins, Janis

Publication type:

Article

A resting-state fMRI study of obese females between pre- and postprandial states before and after bariatric surgery.

Published in:

European Journal of Neuroscience, 2017, v. 45, n. 3, p. 333, doi. 10.1111/ejn.13428

By:

Wiemerslage, Lyle;
Zhou, Wei;
Olivo, Gaia;
Stark, Julia;
Hogenkamp, Pleunie S.;
Larsson, Elna‐Marie;
Sundbom, Magnus;
Schiöth, Helgi B.;
Foxe, John

Publication type:

Article

An obesity-associated risk allele within the FTO gene affects human brain activity for areas important for emotion, impulse control and reward in response to food images.

Published in:

European Journal of Neuroscience, 2016, v. 43, n. 9, p. 1173, doi. 10.1111/ejn.13177

By:

Wiemerslage, Lyle;
Nilsson, Emil K.;
Solstrand Dahlberg, Linda;
Ence‐Eriksson, Fia;
Castillo, Sandra;
Larsen, Anna L.;
Bylund, Simon B. A.;
Hogenkamp, Pleunie S.;
Olivo, Gaia;
Bandstein, Marcus;
Titova, Olga E.;
Larsson, Elna‐Marie;
Benedict, Christian;
Brooks, Samantha J.;
Schiöth, Helgi B.;
Foxe, John

Publication type:

Article

The Drosophila Kctd-family homologue Kctd12-like modulates male aggression and mating behaviour.

Published in:

European Journal of Neuroscience, 2014, v. 40, n. 3, p. 2513, doi. 10.1111/ejn.12619

By:

Williams, Michael J.;
Goergen, Philip;
Phad, Ganesh;
Fredriksson, Robert;
Schiöth, Helgi B.

Publication type:

Article

Disruption of Accumbens and Thalamic White Matter Connectivity Revealed by Diffusion Tensor Tractography in Young Men with Genetic Risk for Obesity.

Published in:

Frontiers in Human Neuroscience, 2018, p. 1, doi. 10.3389/fnhum.2018.00075

By:

Olivo, Gaia;
Latini, Francesco;
Wiemerslage, Lyle;
Larsson, Elna-Marie;
Schiöth, Helgi B.

Publication type:

Article

Phonological working memory is adversely affected in adults with anorexia nervosa: a systematic literature review.

Published in:

Eating & Weight Disorders, 2022, v. 27, n. 6, p. 1931, doi. 10.1007/s40519-022-01370-1

By:

Dahlén, Amelia D.;
Gaudio, Santino;
Schiöth, Helgi B.;
Brooks, Samantha J.

Publication type:

Article

Altered thalamo–cortical and occipital–parietal–temporal–frontal white matter connections in patients with anorexia and bulimia nervosa: a systematic review of diffusion tensor imaging studies.

Published in:

Journal of Psychiatry & Neuroscience, 2019, v. 44, n. 5, p. 324, doi. 10.1503/jpn.180121

By:

Gaudio, Santino;
Carducci, Filippo;
Piervincenzi, Claudia;
Olivo, Gaia;
Schiöth, Helgi B.

Publication type:

Article

Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet.

Published in:

Lipids in Health & Disease, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1476-511X-12-2

By:

Cedernaes, Jonathan;
Alsiö, Johan;
Västermark, Åke;
Risérus, Ulf;
Schiöth, Helgi B.

Publication type:

Article

A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease.

Published in:

BMC Genomics, 2016, v. 17, p. 1, doi. 10.1186/s12864-016-2814-z

By:

Schiöth, Helgi B.;
Boström, Adrian;
Murphy, Susan K.;
Erhart, Wiebke;
Hampe, Jochen;
Moylan, Cynthia;
Mwinyi, Jessica

Publication type:

Article

Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome.

Published in:

BMC Genomics, 2016, v. 17, p. 1, doi. 10.1186/s12864-016-2592-7

By:

Attwood, Misty M.;
Krishnan, Arunkumar;
Pivotti, Valentina;
Yazdi, Samira;
Sällman Almén, Markus;
Schiöth, Helgi B.

Publication type:

Article

Defining the gene repertoire and spatiotemporal expression profiles of adhesion G protein-coupled receptors in zebrafish.

Published in:

BMC Genomics, 2015, v. 16, n. 1, p. 2, doi. 10.1186/s12864-015-1296-8

By:

Harty, Breanne L.;
Krishnan, Arunkumar;
Sanchez, Nicholas E.;
Schiöth, Helgi B.;
Monk, Kelly R.

Publication type:

Article

The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals.

Published in:

BMC Evolutionary Biology, 2014, v. 14, n. 1, p. 375, doi. 10.1186/s12862-014-0270-4

By:

Krishnan, Arunkumar;
Dnyansagar, Rohit;
Almén, Markus Sällman;
Williams, Michael J.;
Fredriksson, Robert;
Manoj, Narayanan;
Schiöth, Helgi B.

Publication type:

Article

Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae.

Published in:

BMC Evolutionary Biology, 2011, v. 11, n. 1, p. 123, doi. 10.1186/1471-2148-11-123

By:

Västermark, Åke;
Almén, Markus Sällman;
Simmen, Martin W.;
Fredriksson, Robert;
Schiöth, Helgi B.

Publication type:

Article

SPRIT: Identifying horizontal gene transfer in rooted phylogenetic trees.

Published in:

BMC Evolutionary Biology, 2010, v. 10, p. 1, doi. 10.1186/1471-2148-10-42

By:

Hill, Tobias;
Nordström, Karl J. V.;
Thollesson, Mikael;
Säfström, Tommy M.;
Vernersson, Andreas K. E.;
Fredriksson, Robert;
Schiöth, Helgi B.

Publication type:

Article

The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors.

Published in:

BMC Evolutionary Biology, 2008, v. 8, p. 1, doi. 10.1186/1471-2148-8-9

By:

Nordström, Karl J. V.;
Fredriksson, Robert;
Schiöth, Helgi B.

Publication type:

Article

Misdiagnosis of diabetic foot ulcer in patients with undiagnosed skin malignancies.

Published in:

International Wound Journal, 2022, v. 19, n. 4, p. 871, doi. 10.1111/iwj.13688

By:

Lyundup, Alexey V.;
Balyasin, Maxim V.;
Maksimova, Nadezhda V.;
Kovina, Marina V.;
Krasheninnikov, Mikhail E.;
Dyuzheva, Tatiana G.;
Yakovenko, Sergey A.;
Appolonova, Svetlana A.;
Schiöth, Helgi B.;
Klabukov, Ilya D.

Publication type:

Article

The G Protein-Coupled Receptor Subset of the Chicken Genome.

Published in:

PLoS Computational Biology, 2006, v. 2, n. 6, p. e54, doi. 10.1371/journal.pcbi.0020054

By:

Lagerström, Malin C.;
Hellström, Anders R.;
Gloriam, David E.;
Larsson, Thomas P.;
Schiöth, Helgi B.;
Fredriksson, Robert

Publication type:

Article