Found: 6

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  • Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD.

    Published in:
    Scientific Reports, 2016, p. 20877, doi. 10.1038/srep20877
    By:
    • Boeynaems, Steven;
    • Bogaert, Elke;
    • Michiels, Emiel;
    • Gijselinck, Ilse;
    • Sieben, Anne;
    • Jovičić, Ana;
    • De Baets, Greet;
    • Scheveneels, Wendy;
    • Steyaert, Jolien;
    • Cuijt, Ivy;
    • Verstrepen, Kevin J.;
    • Callaerts, Patrick;
    • Rousseau, Frederic;
    • Schymkowitz, Joost;
    • Cruts, Marc;
    • Van Broeckhoven, Christine;
    • Van Damme, Philip;
    • Gitler, Aaron D.;
    • Robberecht, Wim;
    • Van Den Bosch, Ludo
    Publication type:
    Article

  • HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease.

    Published in:
    2018
    By:
    • Benoy, Veronick;
    • Van Helleputte, Lawrence;
    • Prior, Robert;
    • d'Ydewalle, Constantin;
    • Haeck, Wanda;
    • Geens, Natasja;
    • Scheveneels, Wendy;
    • Schevenels, Begga;
    • Cader, M. Zameel;
    • Talbot, Kevin;
    • Kozikowski, Alan P.;
    • Berghe, Pieter Vanden;
    • Van Damme, Philip;
    • Robberecht, Wim;
    • Van Den Bosch, Ludo;
    • Vanden Berghe, Pieter
    Publication type:
    journal article

  • PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport.

    Published in:
    Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-024-02689-y
    By:
    • Tziortzouda, Paraskevi;
    • Steyaert, Jolien;
    • Scheveneels, Wendy;
    • Sicart, Adria;
    • Stoklund Dittlau, Katarina;
    • Barbosa Correia, Adriana Margarida;
    • Burg, Thibaut;
    • Pal, Arun;
    • Hermann, Andreas;
    • Van Damme, Philip;
    • Moens, Thomas G.;
    • Van Den Bosch, Ludo
    Publication type:
    Article

  • A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.

    Published in:
    Acta Neuropathologica, 2018, v. 135, n. 3, p. 427, doi. 10.1007/s00401-017-1796-5
    By:
    • Swinnen, Bart;
    • Bento-Abreu, Andre;
    • Gendron, Tania F.;
    • Boeynaems, Steven;
    • Bogaert, Elke;
    • Nuyts, Rik;
    • Timmers, Mieke;
    • Scheveneels, Wendy;
    • Hersmus, Nicole;
    • Wang, Jiou;
    • Mizielinska, Sarah;
    • Isaacs, Adrian M.;
    • Petrucelli, Leonard;
    • Lemmens, Robin;
    • Van Damme, Philip;
    • Van Den Bosch, Ludo;
    • Robberecht, Wim
    Publication type:
    Article

  • FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteins.

    Published in:
    Human Molecular Genetics, 2018, v. 27, n. 23, p. 4103, doi. 10.1093/hmg/ddy303
    By:
    • Steyaert, Jolien;
    • Scheveneels, Wendy;
    • Vanneste, Joni;
    • Damme, Philip Van;
    • Robberecht, Wim;
    • Callaerts, Patrick;
    • Bogaert, Elke;
    • Bosch, Ludo Van Den
    Publication type:
    Article

  • Genetic ablation of IP<sub>3</sub> receptor 2 increases cytokines and decreases survival of SOD1<sup>G93A</sup> mice.

    Published in:
    Human Molecular Genetics, 2016, v. 25, n. 16, p. 3491, doi. 10.1093/hmg/ddw190
    By:
    • Staats, Kim A.;
    • Humblet-Baron, Stephanie;
    • Bento-Abreu, Andre;
    • Scheveneels, Wendy;
    • Nikolaou, Alexandros;
    • Deckers, Kato;
    • Lemmens, Robin;
    • Goris, An;
    • Van Ginderachter, Jo A.;
    • Van Damme, Philip;
    • Chihiro Hisatsune;
    • Mikoshiba, Katsuhiko;
    • Liston, Adrian;
    • Robberecht, Wim;
    • Van Den Bosch, Ludo
    Publication type:
    Article