Found: 68
Select item for more details and to access through your institution.
The SGK1 Kinase Inhibitor SI113 Sensitizes Theranostic Effects of the <sup>64</sup>CuCl<sub>2</sub> in Human Glioblastoma Multiforme Cells.
- Published in:
- Cellular Physiology & Biochemistry (Karger AG), 2017, v. 43, n. 1, p. 108, doi. 10.1159/000480328
- By:
- Publication type:
- Article
SGK1, the New Player in the Game of Resistance: Chemo-Radio Molecular Target and Strategy for Inhibition.
- Published in:
- Cellular Physiology & Biochemistry (Karger AG), 2016, v. 39, n. 5, p. 1863, doi. 10.1159/000447885
- By:
- Publication type:
- Article
New Insights into the LANCL2- ABA Binding Mode towards the Evaluation of New LANCL Agonists.
- Published in:
- Pharmaceutics, 2023, v. 15, n. 12, p. 2754, doi. 10.3390/pharmaceutics15122754
- By:
- Publication type:
- Article
Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4- d ]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme.
- Published in:
- Pharmaceutics, 2023, v. 15, n. 2, p. 453, doi. 10.3390/pharmaceutics15020453
- By:
- Publication type:
- Article
Anti-Survival Effect of SI306 and Its Derivatives on Human Glioblastoma Cells.
- Published in:
- Pharmaceutics, 2022, v. 14, n. 7, p. N.PAG, doi. 10.3390/pharmaceutics14071399
- By:
- Publication type:
- Article
Recent Advances in the Discovery of SIRT1/2 Inhibitors via Computational Methods: A Perspective.
- Published in:
- Pharmaceuticals (14248247), 2024, v. 17, n. 5, p. 601, doi. 10.3390/ph17050601
- By:
- Publication type:
- Article
Sweet Cherry Extract as Permeation Enhancer of Tyrosine Kinase Inhibitors: A Promising Prospective for Future Oral Anticancer Therapies.
- Published in:
- Pharmaceuticals (14248247), 2023, v. 16, n. 11, p. 1527, doi. 10.3390/ph16111527
- By:
- Publication type:
- Article
Identification and Biological Characterization of the Pyrazolo[3,4- d ]pyrimidine Derivative SI388 Active as Src Inhibitor.
- Published in:
- Pharmaceuticals (14248247), 2023, v. 16, n. 7, p. 958, doi. 10.3390/ph16070958
- By:
- Publication type:
- Article
Probing In Silico the Benzimidazole Privileged Scaffold for the Development of Drug-like Anti-RSV Agents.
- Published in:
- Pharmaceuticals (14248247), 2021, v. 14, n. 12, p. 1307, doi. 10.3390/ph14121307
- By:
- Publication type:
- Article
Journey on Naphthoquinone and Anthraquinone Derivatives: New Insights in Alzheimer's Disease.
- Published in:
- Pharmaceuticals (14248247), 2021, v. 14, n. 1, p. 33, doi. 10.3390/ph14010033
- By:
- Publication type:
- Article
Virtual Screening Combined with Enzymatic Assays to Guide the Discovery of Novel SIRT2 Inhibitors.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9363, doi. 10.3390/ijms24119363
- By:
- Publication type:
- Article
Proton Therapy and Src Family Kinase Inhibitor Combined Treatments on U87 Human Glioblastoma Multiforme Cell Line.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 19, p. 4745, doi. 10.3390/ijms20194745
- By:
- Publication type:
- Article
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation.
- Published in:
- Cellular Physiology & Biochemistry (Karger AG), 2015, v. 35, n. 5, p. 2006, doi. 10.1159/000374008
- By:
- Publication type:
- Article
Autophagy Inhibition Enhances Anti-Glioblastoma Effects of Pyrazolo[3,4- d ]pyrimidine Tyrosine Kinase Inhibitors.
- Published in:
- Life (2075-1729), 2022, v. 12, n. 10, p. 1503, doi. 10.3390/life12101503
- By:
- Publication type:
- Article
Inhibition of serum- and glucocorticoid-induced kinase 1 ameliorates hydrocephalus in preclinical models.
- Published in:
- Fluids & Barriers of the CNS, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12987-023-00461-0
- By:
- Publication type:
- Article
The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2019, v. 38, n. 1, p. N.PAG, doi. 10.1186/s13046-019-1212-1
- By:
- Publication type:
- Article
The small molecule SI113 hinders epithelial‐to‐mesenchymal transition and subverts cytoskeletal organization in human cancer cells.
- Published in:
- Journal of Cellular Physiology, 2019, v. 234, n. 12, p. 22529, doi. 10.1002/jcp.28816
- By:
- Publication type:
- Article
SGK1 affects RAN/RANBP1/RANGAP1 via SP1 to play a critical role in pre-miRNA nuclear export: a new route of epigenomic regulation.
- Published in:
- Scientific Reports, 2017, p. 45361, doi. 10.1038/srep45361
- By:
- Publication type:
- Article
Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: nanosystem approaches for drug delivery.
- Published in:
- Scientific Reports, 2016, p. 21509, doi. 10.1038/srep21509
- By:
- Publication type:
- Article
Molecular Characterization of c-Abl/c-Src Kinase Inhibitors Targeted against Murine Tumour Progenitor Cells that Express Stem Cell Markers.
- Published in:
- PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0014143
- By:
- Publication type:
- Article
Pyrazolo[3,4- d ]pyrimidine Tyrosine Kinase Inhibitors Induce Oxidative Stress in Patient-Derived Glioblastoma Cells.
- Published in:
- Brain Sciences (2076-3425), 2021, v. 11, n. 7, p. 884, doi. 10.3390/brainsci11070884
- By:
- Publication type:
- Article
Starch/Poly(glycerol-adipate) Nanocomposites: A Novel Oral Drug Delivery Device.
- Published in:
- Coatings (2079-6412), 2020, v. 10, n. 2, p. 125, doi. 10.3390/coatings10020125
- By:
- Publication type:
- Article
New Therapeutic Strategy for Overcoming Multidrug Resistance in Cancer Cells with Pyrazolo[3,4- d ]pyrimidine Tyrosine Kinase Inhibitors.
- Published in:
- Cancers, 2021, v. 13, n. 21, p. 5308, doi. 10.3390/cancers13215308
- By:
- Publication type:
- Article
Src Inhibitors Pyrazolo[3,4-d]pyrimidines, Si306 and Pro-Si306, Inhibit Focal Adhesion Kinase and Suppress Human Glioblastoma Invasion In Vitro and In Vivo.
- Published in:
- Cancers, 2020, v. 12, n. 6, p. 1570, doi. 10.3390/cancers12061570
- By:
- Publication type:
- Article
A New Strategy for Glioblastoma Treatment: In Vitro and In Vivo Preclinical Characterization of Si306, a Pyrazolo[3,4-d]Pyrimidine Dual Src/P-Glycoprotein Inhibitor.
- Published in:
- Cancers, 2019, v. 11, n. 6, p. 848, doi. 10.3390/cancers11060848
- By:
- Publication type:
- Article
Recent Studies on Ponatinib in Cancers Other Than Chronic Myeloid Leukemia.
- Published in:
- Cancers, 2018, v. 10, n. 11, p. 430, doi. 10.3390/cancers10110430
- By:
- Publication type:
- Article
Phenylhydrazones as Correctors of a Mutant Cystic Fibrosis Transmembrane Conductance Regulator.
- Published in:
- Archiv der Pharmazie, 2016, v. 349, n. 2, p. 112, doi. 10.1002/ardp.201500352
- By:
- Publication type:
- Article
New SRC/ABL inhibitors for chronic myeloid leukemia therapy show selectivity for T315I ABL mutant CD34 cells.
- Published in:
- 2010
- By:
- Publication type:
- Report
Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling.
- Published in:
- Molecules, 2024, v. 29, n. 8, p. 1739, doi. 10.3390/molecules29081739
- By:
- Publication type:
- Article
Synthetic Heterocyclic Derivatives as Kinase Inhibitors Tested for the Treatment of Neuroblastoma †.
- Published in:
- Molecules, 2021, v. 26, n. 23, p. 7069, doi. 10.3390/molecules26237069
- By:
- Publication type:
- Article
Inhibition of SGK1 ameliorates ventriculomegaly in a genetic rat model via regulation of TRPV4 in the choroid plexus.
- Published in:
- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2334
- By:
- Publication type:
- Article
New pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells.
- Published in:
- FASEB Journal, 2010, v. 24, n. 8, p. 2881, doi. 10.1096/fj.09-148593
- By:
- Publication type:
- Article
SRC Family Kinase Inhibition Through a New Pyrazolo[3,4- d]Pyrimidine Derivative as a Feasible Approach for Glioblastoma Treatment.
- Published in:
- Journal of Cellular Biochemistry, 2015, v. 116, n. 5, p. 856, doi. 10.1002/jcb.25042
- By:
- Publication type:
- Article
Pyrazolo-pyrimidine-derived c-Src inhibitor reduces angiogenesis and survival of squamous carcinoma cells by suppressing vascular endothelial growth factor production and signaling.
- Published in:
- International Journal of Cancer, 2007, v. 120, n. 5, p. 995, doi. 10.1002/ijc.22410
- By:
- Publication type:
- Article
Matrine in association with FD-2 stimulates F508del-cystic fibrosis transmembrane conductance regulator activity in the presence of corrector VX809.
- Published in:
- Molecular Medicine Reports, 2017, v. 16, n. 6, p. 8849, doi. 10.3892/mmr.2017.7736
- By:
- Publication type:
- Article
The SGK1 Kinase Inhibitor SI113 Sensitizes Theranostic Effects of the <sup>64</sup>CuCl<sub>2</sub> in Human Glioblastoma Multiforme Cells.
- Published in:
- Annals of Nutrition & Metabolism, 2017, p. 108, doi. 10.1159/000480328
- By:
- Publication type:
- Article
Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells.
- Published in:
- FASEB Journal, 2008, v. 22, n. 5, p. 1560, doi. 10.1096/fj.07-9873com
- By:
- Publication type:
- Article
Exploring the molecular basis of selectivity in A<sub>1</sub> adenosine receptors agonists: a case study.
- Published in:
- Journal of Computer-Aided Molecular Design, 2003, v. 17, n. 1, p. 39, doi. 10.1023/A:1024530029922
- By:
- Publication type:
- Article
Exploring a New Generation of Pyrimidine and Pyridine Derivatives as Anti-Influenza Agents Targeting the Polymerase PA–PB1 Subunits Interaction.
- Published in:
- Pharmaceutics, 2024, v. 16, n. 7, p. 954, doi. 10.3390/pharmaceutics16070954
- By:
- Publication type:
- Article
Unlocking Potential and Limits of Kinase Inhibitors: The Highway to Enhanced Cancer Targeted Therapy.
- Published in:
- Pharmaceutics, 2024, v. 16, n. 5, p. 625, doi. 10.3390/pharmaceutics16050625
- By:
- Publication type:
- Article
The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells.
- Published in:
- Journal of Cellular Physiology, 2017, v. 232, n. 12, p. 3735, doi. 10.1002/jcp.25850
- By:
- Publication type:
- Article
SRC Family Kinase Inhibition in Ewing Sarcoma Cells Induces p38 MAP Kinase-Mediated Cytotoxicity and Reduces Cell Migration.
- Published in:
- Journal of Cellular Physiology, 2017, v. 232, n. 1, p. 129, doi. 10.1002/jcp.25397
- By:
- Publication type:
- Article
Early investigation of a novel SI306 theranostic prodrug for glioblastoma treatment.
- Published in:
- Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22158
- By:
- Publication type:
- Article
The Pyrazolo[3,4- d ]Pyrimidine Derivative Si306 Encapsulated into Anti-GD2-Immunoliposomes as Therapeutic Treatment of Neuroblastoma.
- Published in:
- Biomedicines, 2022, v. 10, n. 3, p. 659, doi. 10.3390/biomedicines10030659
- By:
- Publication type:
- Article
A Pyrazolo[3,4-d]pyrimidine Compound Reduces Cell Viability and Induces Apoptosis in Different Hematological Malignancies.
- Published in:
- Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00416
- By:
- Publication type:
- Article
5-Aza-2′-Deoxycytidine and Valproic Acid in Combination with CHIR99021 and A83-01 Induce Pluripotency Genes Expression in Human Adult Somatic Cells.
- Published in:
- Molecules, 2021, v. 26, n. 7, p. 1909, doi. 10.3390/molecules26071909
- By:
- Publication type:
- Article
Synthesis, Characterization and HPLC Analysis of the (1 S ,2 S ,5 R)-Diastereomer and the Enantiomer of the Clinical Candidate AR-15512.
- Published in:
- Molecules, 2021, v. 26, n. 4, p. 906, doi. 10.3390/molecules26040906
- By:
- Publication type:
- Article
Synthesis and Antibacterial Evaluation of New Pyrazolo[3,4- d ]pyrimidines Kinase Inhibitors.
- Published in:
- Molecules, 2020, v. 25, n. 22, p. 5354, doi. 10.3390/molecules25225354
- By:
- Publication type:
- Article
Bcr-Abl Allosteric Inhibitors: Where We Are and Where We Are Going to.
- Published in:
- Molecules, 2020, v. 25, n. 18, p. 4210, doi. 10.3390/molecules25184210
- By:
- Publication type:
- Article
Synthesis and Biological Evaluation of Novel (thio)semicarbazone-Based Benzimidazoles as Antiviral Agents against Human Respiratory Viruses.
- Published in:
- Molecules, 2020, v. 25, n. 7, p. 1487, doi. 10.3390/molecules25071487
- By:
- Publication type:
- Article