Works by Schenk, Simon

Results: 41

The Association of Metabolic Syndrome and Obesity With Clinical Hip Osteoarthritis in the Study of Osteoporotic Fractures and the Osteoporotic Fractures in Men Study Cohorts.

Published in:

ACR Open Rheumatology, 2023, v. 5, n. 3, p. 115, doi. 10.1002/acr2.11518

By:

Cheng, Karen Y.;
Strotmeyer, Elsa S.;
Kado, Deborah M.;
Schousboe, John T.;
Schenk, Simon;
Nevitt, Michael;
Lane, Nancy E.;
Hughes‐Austin, Jan M.

Publication type:

Article

The effect of tenotomy, neurotomy, and dual injury on mouse rotator cuff muscles: Consequences for the mouse as a preclinical model.

Published in:

Journal of Orthopaedic Research, 2024, v. 42, n. 6, p. 1170, doi. 10.1002/jor.25786

By:

Gibbons, Michael C.;
Silldorff, Morgan;
Okuno, Hiroshi;
Esparza, Mary C.;
Migdal, Christopher;
Johnson, Seth;
Schenk, Simon;
Ward, Samuel R.

Publication type:

Article

Muscle architectural changes after massive human rotator cuff tear.

Published in:

Journal of Orthopaedic Research, 2016, v. 34, n. 12, p. 2089, doi. 10.1002/jor.23256

By:

Gibbons, Michael C.;
Sato, Eugene J.;
Bachasson, Damien;
Cheng, Timothy;
Azimi, Hassan;
Schenk, Simon;
Engler, Adam J.;
Singh, Anshuman;
Ward, Samuel R.

Publication type:

Article

Skeletal muscle maximal mitochondrial activity in ambulatory children with cerebral palsy.

Published in:

Developmental Medicine & Child Neurology, 2021, v. 63, n. 10, p. 1194, doi. 10.1111/dmcn.14785

By:

Dayanidhi, Sudarshan;
Buckner, Elisa H;
Redmond, Robin S;
Chambers, Henry G;
Schenk, Simon;
Lieber, Richard L

Publication type:

Article

Sex‐based differences in contraction‐stimulated glucose uptake by mouse skeletal muscle.

Published in:

FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.04288

By:

Kang, Ji;
Park, Ji;
Dagoon, Jason;
Schenk, Simon

Publication type:

Article

A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange.

Published in:

2008

By:

Liu, Yi;
Dentin, Renaud;
Chen, Danica;
Hedrick, Susan;
Ravnskjaer, Kim;
Schenk, Simon;
Milne, Jill;
Meyers, David J.;
Cole, Phil;
III, John Yates;
Olefsky, Jerrold;
Guarente, Leonard;
Montminy, Marc

Publication type:

Letter

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.

Published in:

Nature, 2007, v. 450, n. 7170, p. 712, doi. 10.1038/nature06261

By:

Milne, Jill C.;
Lambert, Philip D.;
Schenk, Simon;
Carney, David P.;
Smith, Jesse J.;
Gagne, David J.;
Lei Jin;
Boss, Olivier;
Perni, Robert B.;
Chi B. Vu;
Bemis, Jean E.;
Xie, Roger;
Disch, Jeremy S.;
Pui Yee Ng;
Nunes, Joseph J.;
Lynch, Amy V.;
Hongying Yang;
Galonek, Heidi;
Israelian, Kristine;
Choy, Wendy

Publication type:

Article

Network model of skeletal muscle cell signalling predicts differential responses to endurance and resistance exercise training.

Published in:

Experimental Physiology, 2024, v. 109, n. 6, p. 939, doi. 10.1113/EP091712

By:

Fowler, Annabelle;
Knaus, Katherine R.;
Khuu, Stephanie;
Khalilimeybodi, Ali;
Schenk, Simon;
Ward, Samuel R.;
Fry, Andrew C.;
Rangamani, Padmini;
McCulloch, Andrew D.

Publication type:

Article

G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 7, p. 2444, doi. 10.1172/JCI61953

By:

Osborn, Olivia;
Oh, Da Young;
McNelis, Joanne;
Sanchez-Alavez, Manuel;
Talukdar, Saswata;
Min Lu;
Li, PingPing;
Thiede, Lucinda;
Morinaga, Hidetaka;
Kim, Jane J.;
Heinrichsdorff, Jan;
Nalbandian, Sarah;
Ofrecio, Jachelle M.;
Scadeng, Miriam;
Schenk, Simon;
Hadcock, John;
Bartfai, Tamas;
Olefsky, Jerrold M.

Publication type:

Article

Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction.

Published in:

2011

By:

Schenk, Simon;
McCurdy, Carrie E.;
Philp, Andrew;
Chen, Mark Z.;
Holliday, Michael J.;
Bandyopadhyay, Gautum K.;
Osborn, Olivia;
Baar, Keith;
Olefsky1, Jerrold M.;
Olefsky, Jerrold M

Publication type:

journal article

Insulin sensitivity: modulation by nutrients and inflammation.

Published in:

2008

By:

Schenk, Simon;
Saberi, Maziyar;
Olefsky, Jerrold M.

Publication type:

journal article

Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance.

Published in:

2007

By:

Schenk, Simon;
Horowitz, Jeffrey F.

Publication type:

journal article

p300 and cAMP response element‐binding protein‐binding protein in skeletal muscle homeostasis, contractile function, and survival.

Published in:

Journal of Cachexia, Sarcopenia & Muscle, 2020, v. 11, n. 2, p. 464, doi. 10.1002/jcsm.12522

By:

Svensson, Kristoffer;
LaBarge, Samuel A.;
Sathe, Abha;
Martins, Vitor F.;
Tahvilian, Shahriar;
Cunliffe, Jennifer M.;
Sasik, Roman;
Mahata, Sushil K.;
Meyer, Gretchen A.;
Philp, Andrew;
David, Larry L.;
Ward, Samuel R.;
McCurdy, Carrie E.;
Aslan, Joseph E.;
Schenk, Simon

Publication type:

Article

Skeletal muscle fiber-type specific succinate dehydrogenase activity in cerebral palsy.

Published in:

2017

By:

Zogby, Andrew M.;
Dayanidhi, Sudarshan;
Chambers, Henry G.;
Schenk, Simon;
Lieber, Richard L.

Publication type:

journal article

Heterogeneous muscle gene expression patterns in patients with massive rotator cuff tears.

Published in:

PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0190439

By:

Gibbons, Michael C.;
Fisch, Kathleen M.;
Pichika, Rajeswari;
Cheng, Timothy;
Engler, Adam J.;
Schenk, Simon;
Lane, John G.;
Singh, Anshu;
Ward, Samuel R.

Publication type:

Article

Acute glucoregulatory and vascular outcomes of three strategies for interrupting prolonged sitting time in postmenopausal women: A pilot, laboratory-based, randomized, controlled, 4-condition, 4-period crossover trial.

Published in:

PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0188544

By:

Kerr, Jacqueline;
Crist, Katie;
Vital, Daniela G.;
Dillon, Lindsay;
Aden, Sabrina A.;
Trivedi, Minaxi;
Castellanos, Luis R.;
Godbole, Suneeta;
Li, Hongying;
Allison, Matthew A.;
Khemlina, Galina L.;
Takemoto, Michelle L.;
Schenk, Simon;
Sallis, James F.;
Grace, Megan;
Dunstan, David W.;
Natarajan, Loki;
LaCroix, Andrea Z.;
Sears, Dorothy D.

Publication type:

Article

Effects of Dietary Carbohydrate Restriction with High Protein Intake on Protein Metabolism and the Somatotropic Axis.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 9, p. 5175, doi. 10.1210/jc.2005-0559

By:

Harber, Matthew P.;
Schenk, Simon;
Barkan, Ariel L.;
Horowitz, Jeffrey F.

Publication type:

Article

Paraspinal muscles in individuals undergoing surgery for lumbar spine pathology lack a myogenic response to an acute bout of resistance exercise.

Published in:

JOR Spine, 2024, v. 7, n. 1, p. 1, doi. 10.1002/jsp2.1291

By:

Shahidi, Bahar;
Anderson, Bradley;
Ordaz, Angel;
Berry, David B.;
Ruoss, Severin;
Zlomislic, Vinko;
Allen, R. Todd;
Garfin, Steven R.;
Farshad, Mazda;
Schenk, Simon;
Ward, Samuel R.

Publication type:

Article

SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 5, p. 1363, doi. 10.1128/MCB.00705-08

By:

Yoshizaki, Takeshi;
Milne, Jill C.;
Imamura, Takeshi;
Schenk, Simon;
Sonoda, Noriyuki;
Babendure, Jennie L.;
Juu-Chin Lu;
Smith, Jesse J.;
Jirousek, Michael R.;
Olefsky, Jerrold M.

Publication type:

Article

Paraspinal muscle gene expression across different aetiologies in individuals undergoing surgery for lumbar spine pathology.

Published in:

European Spine Journal, 2023, v. 32, n. 4, p. 1123, doi. 10.1007/s00586-023-07543-5

By:

Ordaz, Angel;
Anderson, Brad;
Zlomislic, Vinko;
Allen, R. Todd;
Garfin, Steven R.;
Schuepbach, Regula;
Farshad, Mazda;
Schenk, Simon;
Ward, Samuel R.;
Shahidi, Bahar

Publication type:

Article

Rapamycin does not prevent increases in myofibrillar or mitochondrial protein synthesis following endurance exercise.

Published in:

Journal of Physiology, 2015, v. 593, n. 18, p. 4275, doi. 10.1113/JP271219

By:

Philp, Andrew;
Schenk, Simon;
Perez‐Schindler, Joaquin;
Hamilton, D. Lee;
Breen, Leigh;
Laverone, Erin;
Jeromson, Stewart;
Phillips, Stuart M.;
Baar, Keith

Publication type:

Article

Improved insulin sensitivity after weight loss and exercise training is mediated by a reduction in plasma fatty acid mobilization, not enhanced oxidative capacity.

Published in:

Journal of Physiology, 2009, v. 587, n. 20, p. 4949, doi. 10.1113/jphysiol.2009.175489

By:

Schenk, Simon;
Harber, Matthew P.;
Shrivastava, Cara R.;
Burant, Charles F.;
Horowitz, Jeffrey F.

Publication type:

Article

p300 is not required for metabolic adaptation to endurance exercise training.

Published in:

FASEB Journal, 2016, v. 30, n. 4, p. 1623, doi. 10.1096/fj.15-281741

By:

LaBarge, Samuel A.;
Migdal, Christopher W.;
Buckner, Elisa H.;
Hiroshi Okuno;
Gertsman, Ilya;
Stocks, Ben;
Barshop, Bruce A.;
Nalbandian, Sarah R.;
Philp, Andrew;
McCurdy, Carrie E.;
Schenk, Simon

Publication type:

Article

Perm1 enhances mitochondrial biogenesis, oxidative capacity, and fatigue resistance in adult skeletal muscle.

Published in:

FASEB Journal, 2016, v. 30, n. 2, p. 674, doi. 10.1096/fj.15-276360

By:

Yoshitake Cho;
Hazen, Bethany C.;
Gandra, Paulo G.;
Ward, Samuel R.;
Schenk, Simon;
Russell, Aaron P.;
Kralli, Anastasia

Publication type:

Article

Urocortin‐2 gene transfer for type‐2 diabetes mellitus (854.10).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.854.10

By:

Gao, Mei Hua;
Lai, Ngai;
Miyanohara, Atsushi;
Giamouridis, Dimosthenis;
Ciaraldi, Theodore;
Schenk, Simon;
Hammond, H. Kirk

Publication type:

Article

Differential regulation of myofibrillar and mitochondrial protein synthesis following acute endurance exercise (702.3).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.702.3

By:

Philp, Andrew;
Schenk, Simon;
Breen, Leigh;
Hamilton, Lee;
Scott, Fraser;
Laverone, Erin;
Phillips, Stu;
Baar, Keith

Publication type:

Article

Systemic fatty acid uptake and skeletal muscle inflammatory pathway activation may contribute to the variability in insulin sensitivity found in obesity.

Published in:

FASEB Journal, 2013, v. 27, p. 855.8, doi. 10.1096/fasebj.27.1_supplement.855.8

By:

Van Pelt, Douglas W.;
Newsom, Sean A.;
Schenk, Simon;
Horowitz, Jeffrey F.

Publication type:

Article

Ceramides Contained in LDL Are Elevated in Type 2 Diabetes and Promote Inflammation and Skeletal Muscle Insulin Resistance.

Published in:

Diabetes, 2013, v. 62, n. 2, p. 401, doi. 10.2337/db12-0686

By:

Boon, James;
Hoy, Andrew J.;
Stark, Romana;
Brown, Russell D.;
Meex, Ruth C.;
Henstridge, Darren C.;
Schenk, Simon;
Meikle, Peter J.;
Horowitz, Jeffrey F.;
Kingwell, Bronwyn A.;
Bruce, Clinton R.;
Watt, Matthew J.

Publication type:

Article

Attenuated Pik3r1 expression prevents insulin resistance and adipose tissue macrophage accumulation in diet-induced obese mice.

Published in:

2012

By:

McCurdy CE;
Schenk S;
Holliday MJ;
Philp A;
Houck JA;
Patsouris D;
Maclean PS;
Majka SM;
Klemm DJ;
Friedman JE;
McCurdy, Carrie E;
Schenk, Simon;
Holliday, Michael J;
Philp, Andrew;
Houck, Julie A;
Patsouris, David;
MacLean, Paul S;
Majka, Susan M;
Klemm, Dwight J;
Friedman, Jacob E

Publication type:

journal article

Attenuated Pik3r1 Expression Prevents Insulin Resistance and Adipose Tissue Macrophage Accumulation in Diet-Induced Obese Mice.

Published in:

Diabetes, 2012, v. 61, n. 10, p. 2495, doi. 10.2337/db11-1433

By:

McCurdy, Carrie E.;
Schenk, Simon;
Holliday, Michael J.;
Philp, Andrew;
Houck, Julie A.;
Patsouris, David;
MacLean, Paul S.;
Majka, Susan M.;
Klemm, Dwight J.;
Friedman, Jacob E.

Publication type:

Article

Agpat1 Decreases Insulin Signaling by Activating the mTOR Pathway.

Published in:

Diabetes, 2007, v. 56, p. A349

By:

Cornford, Andrea S.;
Horowitz, Jeffrey F.;
Schenk, Simon;
Burant, Charles F.;
Subauste, Angela R.

Publication type:

Article

SIRT1 regulates nuclear number and domain size in skeletal muscle fibers.

Published in:

Journal of Cellular Physiology, 2018, v. 233, n. 9, p. 7157, doi. 10.1002/jcp.26542

By:

Ross, Jacob A.;
Levy, Yotam;
Svensson, Kristoffer;
Philp, Andrew;
Schenk, Simon;
Ochala, Julien

Publication type:

Article

Quantifying the Effects of Aging on Morphological and Cellular Properties of Human Female Pelvic Floor Muscles.

Published in:

Annals of Biomedical Engineering, 2021, v. 49, n. 8, p. 1836, doi. 10.1007/s10439-021-02748-5

By:

Rieger, Mary;
Duran, Pamela;
Cook, Mark;
Schenk, Simon;
Shah, Manali;
Jacobs, Marni;
Christman, Karen;
Kado, Deborah M.;
Alperin, Marianna

Publication type:

Article

Knock-Down of IL-1Ra in Obese Mice Decreases Liver Inflammation and Improves Insulin Sensitivity.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107487

By:

Franck, Niclas;
Maris, Michael;
Nalbandian, Sarah;
Talukdar, Saswata;
Schenk, Simon;
Hofmann, Hans-Peter;
Bullough, David;
Osborn, Olivia

Publication type:

Article

Surgical site peptidylarginine deaminase 4 (PAD4), a biomarker of NETosis, correlates with insulin resistance in total joint arthroplasty patients: A preliminary report.

Published in:

PLoS ONE, 2021, v. 16, n. 1, p. 1, doi. 10.1371/journal.pone.0245594

By:

Martins, Vitor F.;
Dobson, Christopher R.;
Begur, Maedha;
Parekh, Jesal;
Ball, Scott T.;
Gonzalez, Francis;
Hughes-Austin, Jan M.;
Schenk, Simon

Publication type:

Article

A Maternal Western-Style Diet Impairs Skeletal Muscle Lipid Metabolism in Adolescent Japanese Macaques.

Published in:

Diabetes, 2023, v. 72, n. 12, p. 1766, doi. 10.2337/db23-0289

By:

Greyslak, Keenan T.;
Hetrick, Byron;
Bergman, Bryan C.;
Dean, Tyler A.;
Wesolowski, Stephanie R.;
Gannon, Maureen;
Schenk, Simon;
Sullivan, Elinor L.;
Aagaard, Kjersti M.;
Kievit, Paul;
Chicco, Adam J.;
Friedman, Jacob E.;
McCurdy, Carrie E.

Publication type:

Article

Maternal Obesity and Western-Style Diet Impair Fetal and Juvenile Offspring Skeletal Muscle Insulin-Stimulated Glucose Transport in Nonhuman Primates.

Published in:

2020

By:

Campodonico-Burnett, William;
Hetrick, Byron;
Wesolowski, Stephanie R.;
Schenk, Simon;
Takahashi, Diana L.;
Dean, Tyler A.;
Sullivan, Elinor L.;
Kievit, Paul;
Gannon, Maureen;
Aagaard, Kjersti;
Friedman, Jacob E.;
McCurdy, Carrie E.

Publication type:

journal article

Cancer‐cell‐secreted extracellular vesicles target p53 to impair mitochondrial function in muscle.

Published in:

EMBO Reports, 2023, v. 24, n. 9, p. 1, doi. 10.15252/embr.202256464

By:

Ruan, Xianhui;
Cao, Minghui;
Yan, Wei;
Jones, Ying Z;
Gustafsson, Åsa B;
Patel, Hemal H;
Schenk, Simon;
Wang, Shizhen Emily

Publication type:

Article

Intrinsic Skeletal Muscle Function and Contraction-Stimulated Glucose Uptake Do Not Vary by Time-of-Day in Mice.

Published in:

Function, 2024, v. 5, n. 6, p. 1, doi. 10.1093/function/zqae035

By:

Fitzgerald, Liam S;
Bremner, Shannon N;
Ward, Samuel R;
Cho, Yoshitake;
Schenk, Simon

Publication type:

Article

Physiological Adaptations to Progressive Endurance Exercise Training in Adult and Aged Rats: Insights from the Molecular Transducers of Physical Activity Consortium (MoTrPAC).

Published in:

Function, 2024, v. 5, n. 4, p. 1, doi. 10.1093/function/zqae014

By:

Schenk, Simon;
Sagendorf, Tyler J;
Many, Gina M;
Lira, Ana K;
de Sousa, Luis G O;
Bae, Dam;
Cicha, Michael;
Kramer, Kyle S;
Muehlbauer, Michael;
Hevener, Andrea L;
Rector, R Scott;
Thyfault, John P;
Williams, John P;
Goodyear, Laurie J;
Esser, Karyn A;
Newgard, Christopher B;
Bodine, Sue C;
Adkins, Joshua N;
Albertson, Brent G;
Amar, David

Publication type:

Article

Calorie Restriction-Induced Increase in Skeletal Muscle Insulin Sensitivity Is Not Prevented by Overexpression of the p55α Subunit of Phosphoinositide 3-Kinase.

Published in:

Frontiers in Physiology, 2018, p. N.PAG, doi. 10.3389/fphys.2018.00789

By:

Martins, Vitor F.;
Tahvilian, Shahriar;
Kang, Ji H.;
Svensson, Kristoffer;
Hetrick, Byron;
Chick, Wallace S.;
Schenk, Simon;
McCurdy, Carrie E.

Publication type:

Article