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Comparison of flow‐FISH and MM–qPCR telomere length assessment techniques for the screening of telomeropathies.
Published in:
Annals of the New York Academy of Sciences, 2020, v. 1466, n. 1, p. 93, doi. 10.1111/nyas.14248
By:
- Ferreira, Monica S. Ventura;
- Kirschner, Martin;
- Halfmeyer, Insa;
- Estrada, Natalia;
- Xicoy, Blanca;
- Isfort, Susanne;
- Vieri, Margherita;
- Zamora, Lurdes;
- Abels, Anne;
- Bouillon, Anne‐Sophie;
- Begemann, Matthias;
- Schemionek, Mirle;
- Maurer, Angela;
- Koschmieder, Steffen;
- Wilop, Stefan;
- Panse, Jens;
- Brümmendorf, Tim H.;
- Beier, Fabian
Publication type:
Article
Differential roles of STAT1 and STAT2 in the sensitivity of JAK2V617F- vs. BCR-ABLpositive cells to interferon alpha.
Published in:
Journal of Hematology & Oncology, 2019, v. 12, n. 1, p. 1, doi. 10.1186/s13045-019-0722-9
By:
- Schubert, Claudia;
- Allhoff, Manuel;
- Tillmann, Stefan;
- Maié, Tiago;
- Costa, Ivan G.;
- Lipka, Daniel B.;
- Schemionek, Mirle;
- Feldberg, Kristina;
- Baumeister, Julian;
- Brümmendorf, Tim H.;
- Chatain, Nicolas;
- Koschmieder, Steffen
Publication type:
Article
Identification of the Adapter Molecule MTSS1 as a Potential Oncogene-Specific Tumor Suppressor in Acute Myeloid Leukemia.
Published in:
PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0125783
By:
- Schemionek, Mirle;
- Kharabi Masouleh, Behzad;
- Klaile, Yvonne;
- Krug, Utz;
- Hebestreit, Katja;
- Schubert, Claudia;
- Dugas, Martin;
- Büchner, Thomas;
- Wörmann, Bernhard;
- Hiddemann, Wolfgang;
- Berdel, Wolfgang E.;
- Brümmendorf, Tim H.;
- Müller-Tidow, Carsten;
- Koschmieder, Steffen
Publication type:
Article
Dissecting Genomic Aberrations in Myeloproliferative Neoplasms by Multiplex-PCR and Next Generation Sequencing.
Published in:
PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0123476
By:
- Kirschner, Martin M. J.;
- Schemionek, Mirle;
- Schubert, Claudia;
- Chatain, Nicolas;
- Sontag, Stephanie;
- Isfort, Susanne;
- Ortiz-Brüchle, Nadina;
- Schmitt, Karla;
- Krüger, Luisa;
- Zerres, Klaus;
- Zenke, Martin;
- Brümmendorf, Tim H.;
- Koschmieder, Steffen
Publication type:
Article
Intracellular Retention of ABL Kinase Inhibitors Determines Commitment to Apoptosis in CML Cells.
Published in:
PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040853
By:
- Lipka, Daniel B.;
- Wagner, Marie-Christine;
- Dziadosz, Marek;
- Schnöder, Tina;
- Heidel, Florian;
- Schemionek, Mirle;
- Melo, Junia V.;
- Kindler, Thomas;
- Müller-Tidow, Carsten;
- Koschmieder, Steffen;
- Fischer, Thomas
Publication type:
Article
Transcriptional alteration of DNA repair genes in Philadelphia chromosome negative myeloproliferative neoplasms.
Published in:
2019
By:
- Kirschner, Martin;
- Bornemann, Anne;
- Schubert, Claudia;
- Gezer, Deniz;
- Kricheldorf, Kim;
- Isfort, Susanne;
- Brümmendorf, Tim H.;
- Schemionek, Mirle;
- Chatain, Nicolas;
- Skorski, Tomasz;
- Koschmieder, Steffen
Publication type:
journal article
Evidence for a pre-existing telomere deficit in non-clonal hematopoietic stem cells in patients with acute myeloid leukemia.
Published in:
2017
By:
- Ventura Ferreira, Mónica;
- Crysandt, Martina;
- Ziegler, Patrick;
- Hummel, Sebastian;
- Wilop, Stefan;
- Kirschner, Martin;
- Schemionek, Mirle;
- Jost, Edgar;
- Wagner, Wolfgang;
- Brümmendorf, Tim;
- Beier, Fabian;
- Ventura Ferreira, Mónica S;
- Brümmendorf, Tim H
Publication type:
journal article
The Unfolded Protein Response Is a Major Driver of LCN2 Expression in BCR–ABL- and JAK2V617F-Positive MPN.
Published in:
Cancers, 2021, v. 13, n. 16, p. 4210, doi. 10.3390/cancers13164210
By:
- Tillmann, Stefan;
- Olschok, Kathrin;
- Schröder, Sarah K.;
- Bütow, Marlena;
- Baumeister, Julian;
- Kalmer, Milena;
- Preußger, Vera;
- Weinbergerova, Barbora;
- Kricheldorf, Kim;
- Mayer, Jiri;
- Kubesova, Blanka;
- Racil, Zdenek;
- Wessiepe, Martina;
- Eschweiler, Jörg;
- Isfort, Susanne;
- Brümmendorf, Tim H.;
- Becker, Walter;
- Schemionek, Mirle;
- Weiskirchen, Ralf;
- Koschmieder, Steffen
Publication type:
Article
Targeting of BCR-ABL1 and IRE1α induces synthetic lethality in Philadelphia-positive acute lymphoblastic leukemia.
Published in:
Carcinogenesis, 2021, v. 42, n. 2, p. 272, doi. 10.1093/carcin/bgaa095
By:
- Vieri, Margherita;
- Preisinger, Christian;
- Schemionek, Mirle;
- Salimi, Azam;
- Patterson, John B;
- Samali, Afshin;
- Brümmendorf, Tim H;
- Appelmann, Iris;
- Masouleh, Behzad Kharabi
Publication type:
Article
XBP1 promotes NRAS<sup>G12D</sup> pre‐B acute lymphoblastic leukaemia through IL‐7 receptor signalling and provides a therapeutic vulnerability for oncogenic RAS.
Published in:
Journal of Cellular & Molecular Medicine, 2023, v. 27, n. 21, p. 3363, doi. 10.1111/jcmm.17904
By:
- Salimi, Azam;
- Schemionek‐Reinders, Mirle;
- Huber, Michael;
- Vieri, Margherita;
- Patterson, John B.;
- Alten, Julia;
- Brümmendorf, Tim H.;
- Kharabi Masouleh, Behzad;
- Appelmann, Iris
Publication type:
Article
Infliximab therapy together with tyrosine kinase inhibition targets leukemic stem cells in chronic myeloid leukemia.
Published in:
2019
By:
- Herrmann, Oliver;
- Kuepper, Maja Kim;
- Bütow, Marlena;
- Costa, Ivan G.;
- Appelmann, Iris;
- Beier, Fabian;
- Luedde, Tom;
- Braunschweig, Till;
- Koschmieder, Steffen;
- Brümmendorf, Tim H.;
- Schemionek, Mirle
Publication type:
journal article
LCP1 triggers mTORC2/AKT activity and is pharmacologically targeted by enzastaurin in hypereosinophilia.
Published in:
Molecular Carcinogenesis, 2020, v. 59, n. 1, p. 87, doi. 10.1002/mc.23131
By:
- Ma, Guangxin;
- Gezer, Deniz;
- Herrmann, Oliver;
- Feldberg, Kristina;
- Schemionek, Mirle;
- Jawhar, Mohamad;
- Reiter, Andreas;
- Brümmendorf, Tim H.;
- Koschmieder, Steffen;
- Chatain, Nicolas
Publication type:
Article
Myelofibrosis at diagnosis is associated with the failure of treatment-free remission in CML patients.
Published in:
Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1212392
By:
- Jacobi, Henrike;
- Vieri, Margherita;
- Bütow, Marlena;
- Namasu, Carolina Y.;
- Flüter, Laura;
- Costa, Ivan G.;
- Maié, Tiago;
- Lindemann-Docter, Katharina;
- Chatain, Nicolas;
- Beier, Fabian;
- Huber, Michael;
- Wagner, Wolfgang;
- Crysandt, Martina;
- Brümmendorf, Tim H.;
- Schemionek, Mirle
Publication type:
Article
Calreticulin-mutant proteins induce megakaryocytic signaling to transform hematopoietic cells and undergo accelerated degradation and Golgi-mediated secretion.
Published in:
Journal of Hematology & Oncology, 2016, v. 9, p. 1, doi. 10.1186/s13045-016-0275-0
By:
- Lijuan Han;
- Schubert, Claudia;
- Köhler, Johanna;
- Schemionek, Mirle;
- Isfort, Susanne;
- Brümmendorf, Tim H.;
- Koschmieder, Steffen;
- Chatain, Nicolas
Publication type:
Article
Combined inhibition of BCR-ABL1 and the proteasome as a potential novel therapeutic approach in BCR-ABL positive acute lymphoblastic leukemia.
Published in:
PLoS ONE, 2022, v. 17, n. 10, p. 1, doi. 10.1371/journal.pone.0268352
By:
- Maletzke, Saskia;
- Salimi, Azam;
- Vieri, Margherita;
- Schroeder, Kema Marlen;
- Schemionek, Mirle;
- Masouleh, Behzad Kharabi;
- Brümmendorf, Tim H.;
- Koschmieder, Steffen;
- Appelmann, Iris
Publication type:
Article
Targeting autophagy increases the efficacy of proteasome inhibitor treatment in multiple myeloma by induction of apoptosis and activation of JNK.
Published in:
BMC Cancer, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12885-022-09775-y
By:
- Salimi, Azam;
- Schroeder, Kema Marlen;
- Schemionek-Reinders, Mirle;
- Vieri, Margherita;
- Maletzke, Saskia;
- Gezer, Deniz;
- Masouleh, Behzad Kharabi;
- Appelmann, Iris
Publication type:
Article
Targeting autophagy increases the efficacy of proteasome inhibitor treatment in multiple myeloma by induction of apoptosis and activation of JNK.
Published in:
2022
By:
- Salimi, Azam;
- Schroeder, Kema Marlen;
- Schemionek-Reinders, Mirle;
- Vieri, Margherita;
- Maletzke, Saskia;
- Gezer, Deniz;
- Masouleh, Behzad Kharabi;
- Appelmann, Iris
Publication type:
journal article

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