Works matching AU Schellens, Jan H. M.


Results: 168
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    Selective Oral MEK1/2 Inhibitor Pimasertib in Metastatic Melanoma: Antitumor Activity in a Phase I, Dose-Escalation Trial.

    Published in:
    Targeted Oncology, 2021, v. 16, n. 1, p. 47, doi. 10.1007/s11523-020-00767-1
    By:
    • Lebbé, Céleste;
    • Italiano, Antoine;
    • Houédé, Nadine;
    • Awada, Ahmad;
    • Aftimos, Philippe;
    • Lesimple, Thierry;
    • Dinulescu, Monica;
    • Schellens, Jan H. M.;
    • Leijen, Suzanne;
    • Rottey, Sylvie;
    • Kruse, Vibeke;
    • Kefford, Richard;
    • Raymond, Eric;
    • Faivre, Sandrine;
    • Pages, Celine;
    • Gomez-Roca, Carlos;
    • Schueler, Armin;
    • Goodstal, Samantha;
    • Massimini, Giorgio;
    • Delord, Jean-Pierre
    Publication type:
    Article
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    Enhanced resolution triple-quadrupole mass spectrometry for ultra-sensitive and quantitative analysis of the investigational anticancer agent EO9 (apaziquone) and its metabolite EO5a in human and dog plasma to support (pre)-clinical studies of EOquin® given intravesically

    Published in:
    Rapid Communications in Mass Spectrometry: RCM, 2008, v. 22, n. 4, p. 462, doi. 10.1002/rcm.3387
    By:
    • Vainchtein, Liia D.;
    • Rosing, Hilde;
    • Mirejovsky, Dorla;
    • Huynh, Van;
    • Lenaz, Luigi;
    • Schellens, Jan H. M.;
    • Beijnen, Jos H.
    Publication type:
    Article
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    Quantitative determination of the novel anticancer drug E7070 (indisulam) and its metabolite (1,4-benzenedisulphonamide) in human plasma, urine and faeces by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry

    Published in:
    Rapid Communications in Mass Spectrometry: RCM, 2004, v. 18, n. 23, p. 2839, doi. 10.1002/rcm.1699
    By:
    • Beumer, Jan Hendrik;
    • Rosing, Hilde;
    • Hillebrand, Michel J. X.;
    • Nan-Offeringa, Lianda G. A. H.;
    • Foley, Karen;
    • Yule, S. Murray;
    • Heck, Albert J. R.;
    • Schellens, Jan H. M.;
    • Beijnen, Jos H.
    Publication type:
    Article
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    A Phase 1, open-label, multicentre study to compare the capsule and tablet formulations of AZD5363 and explore the effect of food on the pharmacokinetic exposure, safety and tolerability of AZD5363 in patients with advanced solid malignancies: OAK.

    Published in:
    2018
    By:
    • Dean, Emma;
    • Banerji, Udai;
    • Schellens, Jan H. M.;
    • Krebs, Matthew G.;
    • Jimenez, Begona;
    • van Brummelen, Emilie;
    • Bailey, Chris;
    • Casson, Ed;
    • Cripps, Diana;
    • Cullberg, Marie;
    • Evans, Stephen;
    • Foxley, Andrew;
    • Lindemann, Justin;
    • Rugman, Paul;
    • Taylor, Nigel;
    • Turner, Guy;
    • Yates, James;
    • Lawrence, Peter
    Publication type:
    journal article
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    Systemic and tumor disposition of platinum after administration of cisplatin or STEALTH liposomal-cisplatin formulations (SPI-077 and SPI-077 B103) in a preclinical tumor model of melanoma.

    Published in:
    Cancer Chemotherapy & Pharmacology, 2004, v. 53, n. 4, p. 329, doi. 10.1007/s00280-003-0719-4
    By:
    • Zamboni, William C.;
    • Gervais, Anne C.;
    • Egorin, Merrill J.;
    • Schellens, Jan H. M.;
    • Zuhowski, Elleanor G.;
    • Pluim, Dick;
    • Joseph, Erin;
    • Hamburger, Deborah R.;
    • Working, Peter K.;
    • Colbern, Gail;
    • Tonda, Margaret E.;
    • Potter, Douglas M.;
    • Eiseman, Julie L.
    Publication type:
    Article
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    Population pharmacokinetics of the novel anticancer agent KRN7000.

    Published in:
    Cancer Chemotherapy & Pharmacology, 2002, v. 49, n. 4, p. 287, doi. 10.1007/s00280-001-0413-3
    By:
    • Crul, Mirjam;
    • Mathôt, Ron A. A.;
    • Giaccone, Giuseppe;
    • Punt, Cornelis J. A.;
    • Rosing, Hilde;
    • Hillebrand, Michel J. X.;
    • Ando, Yoshitaka;
    • Nishi, Nobosuke;
    • Tanaka, Hideji;
    • Schellens, Jan H. M.;
    • Beijnen, Jos H.
    Publication type:
    Article
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