Works by Schekman, Randy

Results: 63

SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from...

Published in:

Nature, 1993, v. 365, n. 6444, p. 347, doi. 10.1038/365347a0

By:

Barlowe, Charles;
Schekman, Randy

Publication type:

Article

Hidden: A Baker's Dozen Ways in Which Research Reporting is Less Transparent than it Could be and Suggestions for Implementing Einstein's Dictum.

Published in:

Science & Engineering Ethics, 2024, v. 30, n. 6, p. 1, doi. 10.1007/s11948-024-00517-w

By:

Siddique, Abu Bakkar;
Shaw, Brian;
Dwyer, Johanna;
Fields, David A.;
Fontaine, Kevin;
Hand, David;
Schekman, Randy;
Alberts, Jeffrey;
Locher, Julie;
Allison, David B.

Publication type:

Article

Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85878

By:

Liang Ma;
Singh, Jasleen;
Schekman, Randy

Publication type:

Article

Regulated Oligomerization Induces Uptake of a Membrane Protein into COPII Vesicles Independent of Its Cytosolic Tail.

Published in:

Traffic, 2014, v. 15, n. 5, p. 531, doi. 10.1111/tra.12157

By:

Springer, Sebastian;
Malkus, Per;
Borchert, Britta;
Wellbrock, Ursula;
Duden, Rainer;
Schekman, Randy

Publication type:

Article

Characterization of the interaction between the Sec61 translocon complex and ppαF using optical tweezers.

Published in:

Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 6, p. 1, doi. 10.1002/pro.4996

By:

Robeson, Luka;
Casanova‐Morales, Nathalie;
Burgos‐Bravo, Francesca;
Alfaro‐Valdés, Hilda M.;
Lesch, Robert;
Ramírez‐Álvarez, Carolina;
Valdivia‐Delgado, Mauricio;
Vega, Marcela;
Matute, Ricardo A.;
Schekman, Randy;
Wilson, Christian A. M.

Publication type:

Article

Sec24p and Sec16p cooperate to regulate the GTP cycle of the COPII coat.

Published in:

EMBO Journal, 2012, v. 31, n. 4, p. 1014, doi. 10.1038/emboj.2011.444

By:

Kung, Leslie F;
Pagant, Silvere;
Futai, Eugene;
D'Arcangelo, Jennifer G;
Buchanan, Roy;
Dittmar, John C;
Reid, Robert J D;
Rothstein, Rodney;
Hamamoto, Susan;
Snapp, Erik L;
Schekman, Randy;
Miller, Elizabeth A

Publication type:

Article

GTP/GDP exchange by Sec12p enables COPII vesicle bud formation on synthetic liposomes.

Published in:

EMBO Journal, 2004, v. 23, n. 21, p. 4146, doi. 10.1038/sj.emboj.7600428

By:

Futai, Eugene;
Hamamoto, Susan;
Orci, Lelio;
Schekman, Randy

Publication type:

Article

Membrane fusion.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 7, p. 658, doi. 10.1038/nsmb.1451

By:

Wickner, William;
Schekman, Randy

Publication type:

Article

THE SECRETS OF SECRETION: PROTEIN TRANSPORT IN CELLS.

Published in:

Frontiers for Young Minds, 2023, p. 1, doi. 10.3389/frym.2023.1063926

By:

Schekman, Randy

Publication type:

Article

Concentrative sorting of secretory cargo proteins into COPII-coated vesicles.

Published in:

Journal of Cell Biology, 2002, v. 159, n. 6, p. 915, doi. 10.1083/jcb.200208074

By:

Malkus, Per;
Feng Jiang;
Schekman, Randy

Publication type:

Article

Sec16p potentiates the action of COPII proteins to bud transport vesicles.

Published in:

Journal of Cell Biology, 2002, v. 158, n. 6, p. 1029, doi. 10.1083/jcb.200207053

By:

Supek, Frantisek;
Madden, David T.;
Hamamoto, Susan;
Orci, Lelio;
Schekman, Randy

Publication type:

Article

A subset of yeast vacuolar protein sorting mutants is blocked in one branch of the exocytic pathway.

Published in:

Journal of Cell Biology, 2002, v. 156, n. 2, p. 271, doi. 10.1083/jcb.200109077

By:

Harsay, Edina;
Schekman, Randy

Publication type:

Article

Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.71982

By:

Xiao-Man Liu;
Liang Ma;
Schekman, Randy

Publication type:

Article

Open science takes on Parkinson's disease.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.66546

By:

RILEY, EKEMINI A. U.;
SCHEKMAN, RANDY

Publication type:

Article

COPII and the regulation of protein sorting in mammals.

Published in:

2012

By:

Zanetti, Giulia;
Pahuja, Kanika Bajaj;
Studer, Sean;
Shim, Soomin;
Schekman, Randy

Publication type:

Correction Notice

COPII and the regulation of protein sorting in mammals.

Published in:

Nature Cell Biology, 2012, v. 14, n. 1, p. 20, doi. 10.1038/ncb2390

By:

Zanetti, Giulia;
Pahuja, Kanika Bajaj;
Studer, Sean;
Shim, Soomin;
Schekman, Randy

Publication type:

Article

Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure.

Published in:

Nature Cell Biology, 2010, v. 12, n. 1, p. 41, doi. 10.1038/ncb2002

By:

Merte, Janna;
Jensen, Devon;
Wright, Kevin;
Sarsfield, Sarah;
Wang, Yanshu;
Schekman, Randy;
Ginty, David D.

Publication type:

Article

Change is good: life outside the nucleus.

Published in:

Nature Cell Biology, 2009, v. 11, n. 11, p. 1274, doi. 10.1038/ncb1109-1274

By:

Schekman, Randy

Publication type:

Article

Merging cultures in the study of membrane traffic.

Published in:

Nature Cell Biology, 2004, v. 6, n. 6, p. 483, doi. 10.1038/ncb0604-483

By:

Schekman, Randy

Publication type:

Article

Dynamics of the COPII coat with GTP and stable analogues.

Published in:

Nature Cell Biology, 2001, v. 3, n. 6, p. 531, doi. 10.1038/35078500

By:

Antonny, Bruno;
Madden, David;
Hamamoto, Susan;
Orci, Lelio;
Schekman, Randy

Publication type:

Article

Les gènes et les protéines qui contrôlent la voie de sécrétion.

Published in:

Biologie Aujourd'hui, 2015, v. 209, n. 1, p. 35, doi. 10.1051/jbio/2015011

By:

Schekman, Randy

Publication type:

Article

Ubiquitin-dependent regulation of COPII coat size and function.

Published in:

Nature, 2012, v. 482, n. 7386, p. 495, doi. 10.1038/nature10822

By:

Jin, Lingyan;
Pahuja, Kanika Bajaj;
Wickliffe, Katherine E.;
Gorur, Amita;
Baumgärtel, Christine;
Schekman, Randy;
Rape, Michael

Publication type:

Article

Remodeling of ER-exit sites initiates a membrane supply pathway for autophagosome biogenesis.

Published in:

EMBO Reports, 2017, v. 18, n. 9, p. 1586, doi. 10.15252/embr.201744559

By:

Ge, Liang;
Zhang, Min;
Kenny, Samuel J;
Liu, Dawei;
Maeda, Miharu;
Saito, Kota;
Mathur, Anandita;
Xu, Ke;
Schekman, Randy

Publication type:

Article

Self-assembly of minimal COPII cages.

Published in:

2003

By:

Antonny, Bruno;
Gounon, Pierre;
Schekman, Randy;
Orci, Lelio

Publication type:

Report

Cranio-lenticulo-sutural dysplasia is caused by a SEC23A mutation leading to abnormal endoplasmic-reticulum-to-Golgi trafficking.

Published in:

2006

By:

Boyadjiev, Simeon A.;
Fromme, J. Christopher;
Ben, Jin;
Chong, Samuel S.;
Nauta, Christopher;
Hur, David J.;
Zhang, George;
Hamamoto, Susan;
Schekman, Randy;
Ravazzola, Mariella;
Orci, Lelio;
Eyaid, Wafaa

Publication type:

Letter

Proteins that carry dual targeting signals can act as tethers between peroxisomes and partner organelles.

Published in:

PLoS Biology, 2024, v. 22, n. 2, p. 1, doi. 10.1371/journal.pbio.3002508

By:

Bittner, Elena;
Stehlik, Thorsten;
Lam, Jason;
Dimitrov, Lazar;
Heimerl, Thomas;
Schöck, Isabelle;
Harberding, Jannik;
Dornes, Anita;
Heymons, Nikola;
Bange, Gert;
Schuldiner, Maya;
Zalckvar, Einat;
Bölker, Michael;
Schekman, Randy;
Freitag, Johannes

Publication type:

Article

SEC mutants and the secretory apparatus.

Published in:

Nature Medicine, 2002, v. 8, n. 10, p. 1055, doi. 10.1038/nm769

By:

Schekman, Randy

Publication type:

Article

Endoplasmic Reticulum Stress-Activated Transcription Factor ATFα Requires the Disulfide Isomerase PDIA5 To Modulate Chemoresistance.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 10, p. 1839, doi. 10.1128/MCB.01484-13

By:

Higa, Arisa;
Taouji, Said;
Lhomond, Stéphanie;
Jensen, Devon;
Fernandez-Zapico, Martin E.;
Simpson, Jeremy C.;
Pasquet, Jean-Max;
Schekman, Randy;
Chevet, Eric

Publication type:

Article

Role of Sec61p in the ER-associated degradation of short-lived transmembrane proteins.

Published in:

Journal of Cell Biology, 2008, v. 181, n. 7, p. 1095, doi. 10.1083/jcb.200804053

By:

Scoff, Daniel C.;
Schekman, Randy

Publication type:

Article

Biogenesis of γ-secretase early in the secretory pathway.

Published in:

Journal of Cell Biology, 2007, v. 179, n. 5, p. 951, doi. 10.1083/jcb.200709012

By:

Kim, Jinoh;
Kleizen, Bertrand;
Choy, Regina;
Thinakaran, Gopal;
Sisodia, Sangram S.;
Schekman, Randy W.

Publication type:

Article

Exomer: a coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast.

Published in:

Journal of Cell Biology, 2006, v. 174, n. 7, p. 973, doi. 10.1083/jcb.200605106

By:

Chao-Wen Wang;
Hamamoto, Susan;
Orci, Lelio;
Schekman, Randy

Publication type:

Article

Annexin A6 mediates calcium-dependent exosome secretion during plasma membrane repair.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.86556

By:

Williams, Justin Krish;
Ngo, Jordan Matthew;
Lehman, Isabelle Madeline;
Schekman, Randy

Publication type:

Article

Syncytin-mediated open-ended membrane tubular connections facilitate the intercellular transfer of cargos including Cas9 protein.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.84391

By:

Congyan Zhang;
Schekman, Randy

Publication type:

Article

Unconventional secretion of a-synuclein mediated by palmitoylated DNAJC5 oligomers.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85837

By:

Shenjie Wu;
Villegas, Nancy C. Hernandez;
Sirkis, Daniel W.;
Thomas-Wright, Iona;
Wade-Martins, Richard;
Schekman, Randy

Publication type:

Article

Cargo selection into COPII vesicles is driven by the Sec24p subunit.

Published in:

EMBO Journal, 2002, v. 21, n. 22, p. 6105, doi. 10.1093/emboj/cdf605

By:

Miller, Elizabeth;
Antonny, Bruno;
Hamamoto, Susan;
Schekman, Randy

Publication type:

Article

e-COP is a structural component of coatomer that functions to stabilize a-COP.

Published in:

EMBO Journal, 1998, v. 17, n. 4, p. 985, doi. 10.1093/emboj/17.4.985

By:

Duden, Rainer;
Kajikawa, Loren;
Wuestehube, Linda;
Schekman, Randy

Publication type:

Article

Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation.

Published in:

EMBO Journal, 1997, v. 16, n. 15, p. 4540, doi. 10.1093/emboj/16.15.4540

By:

Pilon, Marinus;
Schekman, Randy;
Römisch, Karin

Publication type:

Article

Ready...aim...fire!

Published in:

Nature, 1998, v. 396, n. 6711, p. 514, doi. 10.1038/24986

By:

Schekman, Randy

Publication type:

Article

COPII-cargo interactions direct protein sorting into ER-derived transport vesicles.

Published in:

Nature, 1998, v. 391, n. 6663, p. 187, doi. 10.1038/34438

By:

Kuehn, Meta J.;
Herrmann, Johannes M.;
Schekman, Randy

Publication type:

Article

New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells.

Published in:

Journal of Cell Biology, 2019, v. 218, n. 11, p. 3861, doi. 10.1083/jcb.201902028

By:

Bassaganyas, Laia;
Popa, Stephanie J.;
Horlbeck, Max;
Puri, Claudia;
Stewart, Sarah E.;
Campelo, Felix;
Ashok, Anupama;
Butnaru, Cristian M.;
Brouwers, Nathalie;
Heydari, Kartoosh;
Ripoche, Jean;
Weissman, Jonathan;
Rubinsztein, David C.;
Schekman, Randy;
Malhotra, Vivek;
Moreau, Kevin;
Villeneuve, Julien

Publication type:

Article

Unconventional secretion of FABP4 by endosomes and secretory lysosomes.

Published in:

Journal of Cell Biology, 2018, v. 217, n. 2, p. 649, doi. 10.1083/jcb.201705047

By:

Villeneuve, Julien;
Bassaganyas, Laia;
Lepreux, Sebastien;
Chiritoiu, Marioara;
Costet, Pierre;
Ripoche, Jean;
Malhotra, Vivek;
Schekman, Randy

Publication type:

Article

COPII-coated membranes function as transport carriers of intracellular procollagen I.

Published in:

Journal of Cell Biology, 2017, v. 216, n. 6, p. 1745, doi. 10.1083/jcb.201702135

By:

Gorur, Amita;
Lin Yuan;
Schekman, Randy;
Baba, Satoshi;
Kenny, Samuel J.;
Ke Xu

Publication type:

Article

Molecular machinery required for protein transport from the endoplasmic reticulum to the golgi complex.

Published in:

BioEssays, 1990, v. 12, n. 6, p. 253, doi. 10.1002/bies.950120602

By:

Hicke, Linda;
Schekman, Randy

Publication type:

Article

Intercellular transmission of alpha-synuclein.

Published in:

Frontiers in Molecular Neuroscience, 2024, p. 1, doi. 10.3389/fnmol.2024.1470171

By:

Shenjie Wu;
Schekman, Randy W.

Publication type:

Article

Cell biology: A channel for protein waste.

Published in:

Nature, 2004, v. 429, n. 6994, p. 817, doi. 10.1038/429817a

By:

Schekman, Randy

Publication type:

Article

ALG-2 Attenuates COPII Budding In Vitro and Stabilizes the Sec23/Sec31A Complex.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075309

By:

la Cour, Jonas M.;
Schindler, Adam J.;
Berchtold, Martin W.;
Schekman, Randy

Publication type:

Article

Sorting Signals That Mediate Traffic of Chitin Synthase III between the TGN/Endosomes and to the Plasma Membrane in Yeast.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046386

By:

Starr, Trevor L.;
Pagant, Silvere;
Wang, Chao-Wen;
Schekman, Randy

Publication type:

Article

SEC24 isoform specificity regulates the assembly of γ‐secretase from dimeric subcomplexes: Molecular and cell biology/presenilins.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042844

By:

Wouters, Rosanne;
Michiels, Christine;
Kleizen, Bertrand;
Dillen, Katleen;
Vermeire, Wendy;
Demedts, David;
Sannerud, Ragna;
Schekman, Randy;
Annaert, Wim

Publication type:

Article

BIOCHEMICAL ANALYSIS OF TREM2 DISEASE MUTATIONS.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1149, doi. 10.1016/j.jalz.2016.07.046

By:

Sirkis, Daniel W.;
Aparicio, Renan E.;
Schekman, Randy

Publication type:

Article

Coordinating a new approach to basic research into Parkinson’s disease.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.51167

By:

SCHEKMAN, RANDY;
RILEY, EKEMINI A. U.

Publication type:

Article