Works by Scheinin, Harry

Results: 49

Prolonged Central μ-Opioid Receptor Occupancy after Single and Repeated Nalmefene Dosing.

Published in:

Neuropsychopharmacology, 2005, v. 30, n. 12, p. 2245, doi. 10.1038/sj.npp.1300790

By:

Ingman, Kimmo;
Hagelberg, Nora;
Aalto, Sargo;
Någren, Kjell;
Juhakoski, Auni;
Karhuvaara, Sakari;
Kallio, Antero;
Oikonen, Vesa;
Hietala, Jarmo;
Scheinin, Harry

Publication type:

Article

Sensitivity of [C]ORM-13070 to increased extracellular noradrenaline in the CNS - a PET study in human subjects.

Published in:

Psychopharmacology, 2015, v. 232, n. 21/22, p. 4169, doi. 10.1007/s00213-015-3941-y

By:

Lehto, Jussi;
Johansson, Jarkko;
Vuorilehto, Lauri;
Luoto, Pauliina;
Arponen, Eveliina;
Scheinin, Harry;
Rouru, Juha;
Scheinin, Mika

Publication type:

Article

A metabolic profile of xenon and metabolite associations with 6-month mortality after out-of-hospital cardiac arrest: A post-hoc study of the randomised Xe-Hypotheca trial.

Published in:

PLoS ONE, 2024, v. 19, n. 6, p. 1, doi. 10.1371/journal.pone.0304966

By:

Nummela, Aleksi J.;
Scheinin, Harry;
Perola, Markus;
Joensuu, Anni;
Laitio, Ruut;
Arola, Olli;
Grönlund, Juha;
Roine, Risto O.;
Bäcklund, Minna;
Vahlberg, Tero J.;
Laitio, Timo

Publication type:

Article

μ-Receptor agonism with alfentanil increases striatal dopamine D2 receptor binding in man.

Published in:

Synapse, 2002, v. 45, n. 1, p. 25, doi. 10.1002/syn.10078

By:

Hagelberg, Nora;
Kajander, Jaana K.;
Någren, Kjell;
Hinkka, Susanna;
Hietala, Jarmo;
Scheinin, Harry

Publication type:

Article

Renal effects of dexmedetomidine during coronary artery bypass surgery: a randomized placebo-controlled study.

Published in:

BMC Anesthesiology, 2011, v. 11, n. 1, p. 9, doi. 10.1186/1471-2253-11-9

By:

Leino, Kari;
Hynynen, Markku;
Jalonen, Jouko;
Salmenperä, Markku;
Scheinin, Harry;
Aantaa, Riku

Publication type:

Article

Aspoxicillin versus piperacillin in severe abdominal infections--a comparative phase III study.

Published in:

1994

By:

Scheinin, Harry;
Havia, Tapani;
Pekkala, Erkki;
Huovinen, Pentti;
Klossner, Jorma;
Lehto, Heikki;
Niinikoski, Juha;
Scheinin, H;
Havia, T;
Pekkala, E;
Huovinen, P;
Klossner, J;
Lehto, H;
Niinikoski, J

Publication type:

journal article

Biological Day-to-Day Variation and Daytime Changes of Testosterone, Follitropin, Lutropin and Oestradiol-17b in Healthy Men.

Published in:

Clinical Chemistry & Laboratory Medicine, 1998, v. 36, n. 7, p. 485

By:

Ahokoski, Outi;
Virtanen, Arja;
Huupponen, Risto;
Scheinin, Harry;
Salminen, Eeva;
Kairisto, Veli;
Irjala, Kerttu

Publication type:

Article

Heart Rate Variability Dynamics During Low-Dose Propofol and Dexmedetomidine Anesthesia.

Published in:

Annals of Biomedical Engineering, 2012, v. 40, n. 8, p. 1802, doi. 10.1007/s10439-012-0544-1

By:

Tarvainen, Mika;
Georgiadis, Stefanos;
Laitio, Timo;
Lipponen, Jukka;
Karjalainen, Pasi;
Kaskinoro, Kimmo;
Scheinin, Harry

Publication type:

Article

Striatal dopamine D2/D3 receptor availability correlates with individual response characteristics to pain.

Published in:

European Journal of Neuroscience, 2004, v. 20, n. 6, p. 1587, doi. 10.1111/j.1460-9568.2004.03622.x

By:

Pertovaara, Antti;
Martikainen, Ilkka K.;
Hagelberg, Nora;
Mansikka, Heikki;
Någren, Kjell;
Hietala, Jarmo;
Scheinin, Harry

Publication type:

Article

Acute inhibition of oestrogen biosynthesis does not affect serum leptin levels in young men.

Published in:

European Journal of Endocrinology, 2000, v. 142, n. 2, p. 164, doi. 10.1530/eje.0.1420164

By:

Luukkaa, Virve;
Rouru, Juha;
Ahokoski, Outi;
Scheinin, Harry;
Irjala, Kerttu;
Huupponen, Risto

Publication type:

Article

Alterations in heart rate variability in patients with peripheral arterial disease requiring surgical revascularization have limited association with postoperative major adverse cardiovascular and cerebrovascular events.

Published in:

PLoS ONE, 2018, v. 13, n. 9, p. 1, doi. 10.1371/journal.pone.0203519

By:

Utriainen, Karri T.;
Airaksinen, Juhani K.;
Polo, Olli J.;
Scheinin, Harry;
Laitio, Ruut M.;
Leino, Kari A.;
Vahlberg, Tero J.;
Kuusela, Tom A.;
Laitio, Timo T.

Publication type:

Article

CYP2D6 polymorphism is not crucial for the disposition of selegiline*.

Published in:

Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 4, p. 402, doi. 10.1016/S0009-9236(98)90071-6

By:

Scheinin, Harry;
Anttila, Markku;
Dahl, Marja-Liisa;
Karnani, Hari;
Nyman, Leena;
Taavitsainen, Päivi;
Pelkonen, Olavi;
Bertilsson, Leif

Publication type:

Article

Buccal delivery of an α2-adrenergic receptor antagonist, atipamezole, in humans*.

Published in:

Clinical Pharmacology & Therapeutics, 1995, v. 58, n. 5, p. 506, doi. 10.1016/0009-9236(95)90170-1

By:

Huupponen, Risto;
Karhuvaara, Sakari;
Anttila, Markku;
Vuorilehto, Lauri;
Scheinin, Harry

Publication type:

Article

Response to Letter to the Editor.

Published in:

Neurogastroenterology & Motility, 2023, v. 35, n. 8, p. 1, doi. 10.1111/nmo.14616

By:

Cajander, Per;
Omari, Taher;
Scheinin, Harry;
Scheinin, Mika;
Savilampi, Johanna

Publication type:

Article

Effects of dexmedetomidine on pharyngeal swallowing and esophageal motility—A double‐blind randomized cross‐over study in healthy volunteers.

Published in:

Neurogastroenterology & Motility, 2023, v. 35, n. 1, p. 1, doi. 10.1111/nmo.14501

By:

Cajander, Per;
Omari, Taher;
Magnuson, Anders;
Scheinin, Harry;
Scheinin, Mika;
Savilampi, Johanna

Publication type:

Article

Decreased Thalamic Activity Is a Correlate for Disconnectedness during Anesthesia with Propofol, Dexmedetomidine and Sevoflurane But Not S-Ketamine.

Published in:

Journal of Neuroscience, 2023, v. 43, n. 26, p. 4884, doi. 10.1523/JNEUROSCI.2339-22.2023

By:

Kantonen, Oskari;
Laaksonen, Lauri;
Alkire, Michael;
Scheinin, Annalotta;
Långsjö, Jaakko;
Kallionpää, Roosa E.;
Kaisti, Kaike;
Radek, Linda;
Johansson, Jarkko;
Laitio, Timo;
Maksimow, Anu;
Scheinin, Joonas;
Nyman, Mikko;
Scheinin, Mika;
Solin, Olof;
Vahlberg, Tero;
Revonsuo, Antti;
Valli, Katja;
Scheinin, Harry

Publication type:

Article

Foundations of Human Consciousness: Imaging the Twilight Zone.

Published in:

Journal of Neuroscience, 2021, v. 41, n. 8, p. 1769, doi. 10.1523/JNEUROSCI.0775-20.2020

By:

Scheinin, Annalotta;
Kantonen, Oskari;
Alkire, Michael;
Långsjö, Jaakko;
Kallionpää, Roosa E.;
Kaisti, Kaike;
Radek, Linda;
Johansson, Jarkko;
Sandman, Nils;
Nyman, Mikko;
Scheinin, Mika;
Vahlberg, Tero;
Revonsuo, Antti;
Valli, Katja;
Scheinin, Harry

Publication type:

Article

Seasonal Variation in the Brain μ-Opioid Receptor Availability.

Published in:

Journal of Neuroscience, 2021, v. 41, n. 6, p. 1265, doi. 10.1523/JNEUROSCI.2380-20.2020

By:

Lihua Sun;
Jing Tang;
Heidi Liljenbäck;
Aake Honkaniemi;
Virta, Jenni;
Isojärvi, Janne;
Karjalainen, Tomi;
Tatu Kantonen;
Pirjo Nuutila;
Jarmo Hietala;
Valtteri Kaasinen;
Kari Kalliokoski;
Hirvonen, Jussi;
Scheinin, Harry;
Helin, Semi;
Eerola, Kim;
Savontaus, Eriika;
Yatkin, Emrah;
Rinne, Juha O.;
Roivainen, Anne

Publication type:

Article

The influence of dexmedetomidine and propofol on circulating cytokine levels in healthy subjects.

Published in:

BMC Anesthesiology, 2019, v. 19, n. 1, p. N.PAG, doi. 10.1186/s12871-019-0895-3

By:

Kallioinen, Minna;
Scheinin, Annalotta;
Maksimow, Mikael;
Långsjö, Jaakko;
Kaisti, Kaike;
Takala, Riikka;
Vahlberg, Tero;
Valli, Katja;
Salmi, Marko;
Scheinin, Harry;
Maksimow, Anu

Publication type:

Article

Comparison of the prognostic value of early-phase proton magnetic resonance spectroscopy and diffusion tensor imaging with serum neuron-specific enolase at 72 h in comatose survivors of out-of-hospital cardiac arrest—a substudy of the XeHypotheca trial

Published in:

Neuroradiology, 2023, v. 65, n. 2, p. 349, doi. 10.1007/s00234-022-03063-z

By:

Koskensalo, Kalle;
Virtanen, Sami;
Saunavaara, Jani;
Parkkola, Riitta;
Laitio, Ruut;
Arola, Olli;
Hynninen, Marja;
Silvasti, Päivi;
Nukarinen, Eija;
Martola, Juha;
Silvennoinen, Heli M.;
Tiainen, Marjaana;
Roine, Risto O.;
Scheinin, Harry;
Saraste, Antti;
Maze, Mervyn;
Vahlberg, Tero;
Laitio, Timo T.

Publication type:

Article

Tendon graft through the coracoid tunnel versus under the coracoid for coracoclavicular/acromioclavicular reconstruction shows no difference in radiographic or patient-reported outcomes.

Published in:

Archives of Orthopaedic & Trauma Surgery, 2024, v. 144, n. 8, p. 3491, doi. 10.1007/s00402-024-05461-9

By:

Ranne, Juha O.;
Kainonen, Terho U.;
Kanto, Kari J.;
Lehtinen, Janne T.;
Niemi, Pekka T.;
Scheinin, Harry

Publication type:

Article

Bioavailability of dexmedetomidine after extravascular doses in healthy subjects.

Published in:

British Journal of Clinical Pharmacology, 2003, v. 56, n. 6, p. 691, doi. 10.1046/j.1365-2125.2003.01944.x

By:

Anttila, Markku;
Penttilä, Jani;
Helminen, Antti;
Vuorilehto, Lauri;
Scheinin, Harry

Publication type:

Article

Pharmacokinetics of finrozole (MPV-2213ad), a novel selective aromatase inhibitor, in healthy men.

Published in:

British Journal of Clinical Pharmacology, 2001, v. 52, n. 6, p. 702, doi. 10.1046/j.0306-5251.2001.01488.x

By:

Ahokoski, Outi;
Irjala, Kerttu;
Taalikka, Mikko;
Manninen, Pekka;
Halonen, Kaija;
Kangas, Lauri;
Salminen, Eeva;
Huupponen, Risto;
Scheinin, Harry

Publication type:

Article

The influence of drug input rate on the development of tolerance to frusemide.

Published in:

British Journal of Clinical Pharmacology, 1998, v. 46, n. 5, p. 479, doi. 10.1046/j.1365-2125.1998.00802.x

By:

Wakelkamp, Monique;
Alván, Gunnar;
Scheinin, Harry;
Gabrielsson, Johan

Publication type:

Article

Hormonal effects of MPV-2213ad, a new selective aromatase inhibitor, in healthy male subjects. A phase I study.

Published in:

British Journal of Clinical Pharmacology, 1998, v. 45, n. 2, p. 141, doi. 10.1046/j.1365-2125.1998.00654.x

By:

Ahokoski, Outi;
Irjala, Kerttu;
Huupponen, Risto;
Halonen, Kaija;
Salminen, Eeva;
Scheinin, Harry

Publication type:

Article

Cortical glutamate–dopamine interaction and ketamine-induced psychotic symptoms in man.

Published in:

Psychopharmacology, 2005, v. 182, n. 3, p. 375, doi. 10.1007/s00213-005-0092-6

By:

Aalto, Sargo;
Ihalainen, Jouni;
Hirvonen, Jussi;
Kajander, Jaana;
Scheinin, Harry;
Tanila, Heikki;
Någren, Kjell;
Vilkman, Harry;
Gustafsson, Lars L.;
Syvälahti, Erkka;
Hietala, Jarmo

Publication type:

Article

Ketamine does not decrease striatal dopamine D[sub 2] receptor binding in man.

Published in:

Psychopharmacology, 2002, v. 164, n. 4, p. 401, doi. 10.1007/s00213-002-1236-6

By:

Aalto, Sargo;
Hirvonen, Jussi;
Kajander, Jaana;
Scheinin, Harry;
Någren, Kjell;
Vilkman, Harry;
Gustafsson, Lars;
Syvälahti, Erkka;
Hietala, Jarmo

Publication type:

Article

The effects of amitriptyline, citalopram and reboxetine on autonomic nervous system: A randomised placebo-controlled study on healthy volunteers.

Published in:

Psychopharmacology, 2001, v. 154, n. 4, p. 343

By:

Penttilä, Jani;
Syvälahti, Erkka;
Hinkka, Susanna;
Kuusela, Tom;
Scheinin, Harry

Publication type:

Article

Laser bronchoscopy in palliative treatment of malignant obstructing endobronchial tumors.

Published in:

1998

By:

Sipilä, Jukka;
Scheinin, Harry;
Grenman, Reidar;
Sipilä, J;
Scheinin, H;
Grenman, R

Publication type:

journal article

Directional Connectivity between Frontal and Posterior Brain Regions Is Altered with Increasing Concentrations of Propofol.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0113616

By:

Maksimow, Anu;
Silfverhuth, Minna;
Långsjö, Jaakko;
Kaskinoro, Kimmo;
Georgiadis, Stefanos;
Jääskeläinen, Satu;
Scheinin, Harry

Publication type:

Article

Cardiovascular and parasympathetic effects of dexmedetomidine in healthy subjects.

Published in:

2004

By:

Penttilä, Jani;
Halminen, Antti;
Anttila, Markku;
Hinkka, Susanna;
Scheinin, Harry

Publication type:

Report

Detecting a Dexmedetomidine-Evoked Reduction of Noradrenaline Release in the Human Brain with the alpha2C-Adrenoceptor PET Ligand [11C]ORM-13070.

Published in:

Synapse, 2016, v. 70, n. 2, p. 57, doi. 10.1002/syn.21872

By:

LEHTO, JUSSI;
SCHEININ, ANNALOTTA;
JOHANSSON, JARKKO;
MARJAMÄKI, PÄIVI;
ARPONEN, EVELIINA;
SCHEININ, HARRY;
SCHEININ, MIKA

Publication type:

Article

Validation of [11C]ORM-13070 as a PET tracer for alpha2c-adrenoceptors in the human brain.

Published in:

Synapse, 2015, v. 69, n. 3, p. 172, doi. 10.1002/syn.21798

By:

Lehto, Jussi;
Hirvonen, Mika M.;
Johansson, Jarkko;
Kemppainen, Jukka;
Luoto, Pauliina;
Naukkarinen, Tarja;
Oikonen, Vesa;
Arponen, Eveliina;
Rouru, Juha;
Sallinen, Jukka;
Scheinin, Harry;
Vuorilehto, Lauri;
Finnema, Sjoerd J.;
Halldin, Christer;
Rinne, Juha O.;
Scheinin, Mika

Publication type:

Article

Returning from Oblivion: Imaging the Neural Core of Consciousness.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 14, p. 4935, doi. 10.1523/JNEUROSCI.4962-11.2012

By:

Långsjö, Jaakko W.;
Alkire, Michael T.;
Kaskinoro, Kimmo;
Hayama, Hiroki;
Maksimow, Anu;
Kaisti, Kaike K.;
Aalto, Sargo;
Aantaa, Riku;
Jääskeläinen, Satu K.;
Revonsuo, Antti;
Scheinin, Harry

Publication type:

Article

Enhanced Noradrenergic Neuronal Activity Increases Homovanillic Acid Levels in Cerebrospinal Fluid.

Published in:

Journal of Neurochemistry, 1986, v. 47, n. 3, p. 665, doi. 10.1111/j.1471-4159.1986.tb00662.x

By:

Scheinin, Harry

Publication type:

Article

Estimation of cardiac output in a pharmacological trial using a simple method based on arterial blood pressure signal waveform: a comparison with pulmonary thermodilution and echocardiographic methods.

Published in:

European Journal of Clinical Pharmacology, 2006, v. 62, n. 6, p. 401, doi. 10.1007/s00228-006-0115-1

By:

Penttilä, Jani;
Snapir, Amir;
Kentala, Erkki;
Koskenvuo, Juha;
Posti, Jussi;
Scheinin, Mika;
Scheinin, Harry;
Kuusela, Tom

Publication type:

Article

Analysis of rapid heart rate variability in the assessment of anticholinergic drug effects in humans.

Published in:

European Journal of Clinical Pharmacology, 2005, v. 61, n. 8, p. 559, doi. 10.1007/s00228-005-0953-2

By:

Penttilä, Jani;
Kuusela, Tom;
Scheinin, Harry

Publication type:

Article

Effect of the novel anxiolytic drug deramciclane on cytochrome P450 2D6 activity as measured by desipramine pharmacokinetics.

Published in:

European Journal of Clinical Pharmacology, 2004, v. 59, n. 12, p. 893, doi. 10.1007/s00228-003-0714-z

By:

Laine, Kari;
De Bruyn, Steven;
Björklund, Harry;
Rouru, Juha;
H&aul;nninen, Jutta;
Scheinin, Harry;
Anttila, Markku

Publication type:

Article

Pharmacokinetic–pharmacodynamic model for the anticholinergic effect of glycopyrrolate.

Published in:

European Journal of Clinical Pharmacology, 2001, v. 57, n. 2, p. 153, doi. 10.1007/s002280100288

By:

Penttilä, Jani;
Helminen, Antti;
Luomala, Kirsti;
Scheinin, Harry

Publication type:

Article

Ventilator add-on for delivering PET tracer gases.

Published in:

2004

By:

Kaisti KK;
Mäkitalo J;
Sipilä HT;
Teräs MIP;
Scheinin H;
Kaisti, Kaike K;
Mäkitalo, Jukka;
Sipilä, Hannu T;
Teräs, Mika I P;
Scheinin, Harry

Publication type:

journal article

Ventilator Add-On for Delivering PET Tracer Gases.

Published in:

Journal of Nuclear Medicine Technology, 2004, v. 32, n. 2, p. 79

By:

Kaisti, Kaike K.;
Mäkitalo, Jukka;
Sipilä, Hannu T.;
Teräs, Mika I.P.;
Scheinin, Harry

Publication type:

Article

PET in drug discovery and development: an introduction.

Published in:

Annals of Medicine, 1999, v. 31, n. 6, p. 430, doi. 10.3109/07853899908998800

By:

Scheinin, Harry;
Knuuti, Juhani;
Scheinin, Mika

Publication type:

Article

Positron Emission Tomography (PET).

Published in:

2003

By:

Scheinin, Harry

Publication type:

Abstract

Intravenous ethanol increases dopamine release in the ventral striatum in humans: PET study using bolus-plus-infusion administration of [11C]raclopride.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2015, v. 35, n. 3, p. 424, doi. 10.1038/jcbfm.2014.209

By:

Aalto, Sargo;
Ingman, Kimmo;
Alakurtti, Kati;
Kaasinen, Valtteri;
Virkkala, Jussi;
Någren, Kjell;
Rinne, Juha O;
Scheinin, Harry

Publication type:

Article

The effects of d-amphetamine on extrastriatal dopamine D2/D3 receptors: a randomized, double-blind, placebo-controlled PET study with [11C]FLB 457 in healthy subjects.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2009, v. 36, n. 3, p. 475, doi. 10.1007/s00259-008-0969-9

By:

Aalto, Sargo;
Hirvonen, Jussi;
Kaasinen, Valtteri;
Hagelberg, Nora;
Kajander, Jaana;
Någren, Kjell;
Seppälä, Timo;
Rinne, Juha;
Scheinin, Harry;
Hietala, Jarmo

Publication type:

Article

Measurement of central µ-opioid receptor binding in vivo with PET and [11C]carfentanil: a test–retest study in healthy subjects.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2009, v. 36, n. 2, p. 275, doi. 10.1007/s00259-008-0935-6

By:

Hirvonen, Jussi;
Aalto, Sargo;
Hagelberg, Nora;
Maksimow, Anu;
Ingman, Kimmo;
Oikonen, Vesa;
Virkkala, Jussi;
Någren, Kjell;
Scheinin, Harry

Publication type:

Article

Pharmacodynamics and pharmacokinetics of intramuscular dexmedetomidine.

Published in:

Clinical Pharmacology & Therapeutics, 1992, v. 52, n. 5, p. 537, doi. 10.1038/clpt.1992.182

By:

Scheinin, Harry;
Karhuvaara, Sakari;
Olkkola, Klaus T;
Kallio, Antero;
Anttila, Markku;
Vuorilehto, Lauri;
Scheinin, Mika

Publication type:

Article

Effects of dexmedetomidine, a selective α2-adrenoceptor agonist, on hemodynamic control mechanisms.

Published in:

Clinical Pharmacology & Therapeutics, 1989, v. 46, n. 1, p. 33, doi. 10.1038/clpt.1989.103

By:

Kallio, Antero;
Scheinin, Mika;
Koulu, Markku;
Ponkilainen, Riitta;
Ruskoaho, Heikki;
Viinamäki, Osmo;
Scheinin, Harry

Publication type:

Article

Noradrenergic and dopaminergic effects of nomifensine in healthy volunteers.

Published in:

Clinical Pharmacology & Therapeutics, 1987, v. 41, n. 1, p. 88, doi. 10.1038/clpt.1987.15

By:

Scheinin, Mika;
Lindberg, Raija;
Syvälahti, Erkka;
Hietala, Jarmo;
Pihlajamäki, Kalevi;
Scheinin, Harry

Publication type:

Article