Works by Scheiflinger, Friedrich
Results: 23
Structural analysis of the recombinant therapeutic product rFVIII and its PEGylated variants using 2-D DIGE.
- Published in:
- Proteomics - Clinical Applications, 2011, v. 5, n. 9/10, p. 573, doi. 10.1002/prca.201190095
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- Article
Mutation of the surface-exposed amino acid Trp<sup>2313</sup> to Ala in the FVIII C2 domain results in defective secretion of the otherwise functional protein.
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- British Journal of Haematology, 2004, v. 125, n. 5, p. 629, doi. 10.1111/j.1365-2141.2004.04959.x
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- Publication type:
- Article
SHORT REPORT Evaluation of the haemostatic potential of factor VIII-heparin cofactor II hybrid proteins in a mouse model.
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- British Journal of Haematology, 2003, v. 123, n. 4, p. 692, doi. 10.1046/j.1365-2141.2003.04674.x
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- Publication type:
- Article
ADAMTS13 gene defects in two brothers with constitutional thrombotic thrombocytopenic purpura and normalization of von Willebrand factor-cleaving protease activity by recombinant human ADAMTS13.
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- British Journal of Haematology, 2003, v. 120, n. 5, p. 821, doi. 10.1046/j.1365-2141.2003.04183.x
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- Article
Higher expression of fab antibody fragments in a CHO cell line at reduced temperature.
- Published in:
- Biotechnology & Bioengineering, 2003, v. 84, n. 4, p. 433, doi. 10.1002/bit.10793
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- Publication type:
- Article
Thrombotic thrombocytopenic purpura in IgG4-related disease with severe deficiency of ADAMTS-13 activity and IgG4 autoantibody against ADAMTS-13.
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- 2011
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- Publication type:
- journal article
Microchip capillary gel electrophoresis of multiply PEGylated high-molecular-mass glycoproteins.
- Published in:
- Biotechnology Journal, 2012, v. 7, n. 5, p. 635, doi. 10.1002/biot.201100407
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- Publication type:
- Article
Structural analysis of the recombinant therapeutic product rFVIII and its PEGylated variants using 2-D DIGE.
- Published in:
- Electrophoresis, 2011, v. 32, n. 11, p. 1292, doi. 10.1002/elps.201000627
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- Publication type:
- Article
Flow-induced elongation of von Willebrand factor precedes tension-dependent activation.
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- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00230-2
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- Article
Optimization of an Antibody Light Chain Framework Enhances Expression, Biophysical Properties and Pharmacokinetics.
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- Antibodies (2073-4468), 2019, v. 8, n. 3, p. 46, doi. 10.3390/antib8030046
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- Article
A patient with SLE-associated thrombotic microangiopathy and non-neutralizing antibodies against ADAMTS13.
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- 2010
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- Case Study
Expression of recombinant human coagulation factors VII (rFVII) and IX (rFIX) in various cell types, glycosylation analysis, and pharmacokinetic comparison.
- Published in:
- 2011
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- Publication type:
- Abstract
Preclinical safety and efficacy of a new recombinant FIX drug product for treatment of hemophilia B.
- Published in:
- International Journal of Hematology, 2013, v. 98, n. 5, p. 525, doi. 10.1007/s12185-013-1448-z
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- Publication type:
- Article
Differences in N-glycosylation of recombinant human coagulation factor VII derived from BHK, CHO, and HEK293 cells.
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- BMC Biotechnology, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12896-015-0205-1
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- Article
Ca concentration-dependent conformational change of FVIII B-domain observed by atomic force microscopy.
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- Analytical & Bioanalytical Chemistry, 2015, v. 407, n. 20, p. 6051, doi. 10.1007/s00216-015-8778-z
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- Publication type:
- Article
Genome editing for scalable production of alloantigen-free lentiviral vectors for in vivo gene therapy.
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- EMBO Molecular Medicine, 2017, v. 9, n. 11, p. 1558, doi. 10.15252/emmm.201708148
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- Publication type:
- Article
Poor responder to plasma exchange therapy in acquired thrombotic thrombocytopenic purpura is associated with ADAMTS13 inhibitor boosting: visualization of an ADAMTS13 inhibitor complex and its proteolytic clearance from plasma.
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- 2015
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- Publication type:
- journal article
How Full-Length FVIII Benefits from Its Heterogeneity – Insights into the Role of the B-Domain.
- Published in:
- Pharmaceutical Research, 2019, v. 36, n. 5, p. N.PAG, doi. 10.1007/s11095-019-2599-2
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- Publication type:
- Article
The Mystery of Antibodies Against Polyethylene Glycol (PEG) - What do we Know?
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- Pharmaceutical Research, 2016, v. 33, n. 9, p. 2239, doi. 10.1007/s11095-016-1961-x
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- Publication type:
- Article
A Flow-Cytometry-Based Approach to Facilitate Quantification, Size Estimation and Characterization of Sub-visible Particles in Protein Solutions.
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- Pharmaceutical Research, 2015, v. 32, n. 9, p. 2863, doi. 10.1007/s11095-015-1669-3
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- Publication type:
- Article
Development of a Transgenic Mouse Model with Immune Tolerance for Human Coagulation Factor VIIa.
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- Pharmaceutical Research, 2013, v. 30, n. 11, p. 2855, doi. 10.1007/s11095-013-1115-3
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- Publication type:
- Article
Mining ancient proteins for next-generation drugs.
- Published in:
- Nature Biotechnology, 2017, v. 35, n. 1, p. 28, doi. 10.1038/nbt.3762
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- Publication type:
- Article
Immunochemical detection of prion protein on dipsticks prepared with crystalline bacterial cell-surface layers.
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- Transfusion, 2003, v. 43, n. 12, p. 1677, doi. 10.1111/j.0041-1132.2003.00567.x
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- Publication type:
- Article