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Gene editing to induce FOXP3 expression in human CD4<sup>+</sup> T cells leads to a stable regulatory phenotype and function.
- Published in:
- Science Translational Medicine, 2020, v. 12, n. 546, p. 1, doi. 10.1126/scitranslmed.aay6422
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- Publication type:
- Article
Therapeutically relevant engraftment of a CRISPR-Cas9–edited HSC-enriched population with HbF reactivation in nonhuman primates.
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- Science Translational Medicine, 2019, v. 11, n. 503, p. 1, doi. 10.1126/scitranslmed.aaw3768
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- Publication type:
- Article
Correction: The BRCT Domain of PARP-1 Is Required for Immunoglobulin Gene Conversion.
- Published in:
- 2018
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- Publication type:
- Correction Notice
Characterization of homing endonuclease binding and cleavage specificities using yeast surface display SELEX (YSD-SELEX).
- Published in:
- Nucleic Acids Research, 2017, v. 45, n. 3, p. 1, doi. 10.1093/nar/gkw864
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- Publication type:
- Article
Digital detection of endonuclease mediated gene disruption in the HIV provirus.
- Published in:
- Scientific Reports, 2016, p. 20064, doi. 10.1038/srep20064
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- Publication type:
- Article
Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template.
- Published in:
- Science Translational Medicine, 2015, v. 7, n. 307, p. 1, doi. 10.1126/scitranslmed.aac5530
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- Publication type:
- Article
Genome Editing Technologies: Defining a Path to Clinic.
- Published in:
- Molecular Therapy, 2015, v. 23, n. 5, p. 796, doi. 10.1038/mt.2015.54
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- Publication type:
- Article
Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. 10, p. 6463, doi. 10.1093/nar/gku224
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- Publication type:
- Article
megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. 4, p. 2591, doi. 10.1093/nar/gkt1224
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- Publication type:
- Article
Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. 1, p. 1, doi. 10.1093/nar/gkt872
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- Publication type:
- Article
Characterization of three loci for homologous gene targeting and transgene expression.
- Published in:
- Biotechnology & Bioengineering, 2013, v. 110, n. 8, p. 2225, doi. 10.1002/bit.24892
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- Publication type:
- Article
Coupling endonucleases with DNA end-processing enzymes to drive gene disruption.
- Published in:
- Nature Methods, 2012, v. 9, n. 10, p. 973, doi. 10.1038/nmeth.2177
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- Publication type:
- Article
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases.
- Published in:
- Nucleic Acids Research, 2012, v. 40, n. 16, p. 7985, doi. 10.1093/nar/gks502
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- Publication type:
- Article
The B. subtilis MgtE Magnesium Transporter Can Functionally Compensate TRPM7-Deficiency in Vertebrate B-Cells.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044452
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- Publication type:
- Article
Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects.
- Published in:
- Nucleic Acids Research, 2012, v. 40, n. 13, p. 5560, doi. 10.1093/nar/gks179
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- Publication type:
- Article
Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects.
- Published in:
- Nucleic Acids Research, 2012, v. 40, n. 12, p. 5560, doi. 10.1093/nar/gks179
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- Publication type:
- Article
Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space.
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- Nucleic Acids Research, 2012, v. 40, n. 11, p. 4954, doi. 10.1093/nar/gkr1303
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- Publication type:
- Article
Novel reporter systems for facile evaluation of I-SceI-mediated genome editing.
- Published in:
- Nucleic Acids Research, 2012, v. 40, n. 2, p. e14, doi. 10.1093/nar/gkr897
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- Publication type:
- Article
Tracking genome engineering outcome at individual DNA breakpoints.
- Published in:
- Nature Methods, 2011, v. 8, n. 8, p. 671, doi. 10.1038/nmeth.1648
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- Publication type:
- Article
Successful Targeting and Disruption of an Integrated Reporter Lentivirus Using the Engineered Homing Endonuclease Y2 I-Anil.
- Published in:
- PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0016825
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- Publication type:
- Article
The BRCT Domain of PARP-1 Is Required for Immunoglobulin Gene Conversion.
- Published in:
- PLoS Biology, 2010, v. 8, n. 7, p. 1, doi. 10.1371/journal.pbio.1000428
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- Publication type:
- Article
Zinc-finger nucleases: a powerful tool for genetic engineering of animals.
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- Transgenic Research, 2010, v. 19, n. 3, p. 363, doi. 10.1007/s11248-009-9323-7
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- Publication type:
- Article
High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display.
- Published in:
- Nucleic Acids Research, 2009, v. 37, n. 20, p. 6871, doi. 10.1093/nar/gkp726
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- Publication type:
- Article
Exploitation of binding energy for catalysis and design.
- Published in:
- Nature, 2009, v. 461, n. 7268, p. 1300, doi. 10.1038/nature08508
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- Publication type:
- Article
Structure/Function Analysis of PARP-1 in Oxidative and Nitrosative Stress-Induced Monomeric ADPR Formation.
- Published in:
- PLoS ONE, 2009, v. 4, n. 7, p. 1, doi. 10.1371/journal.pone.0006339
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- Publication type:
- Article
Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation.
- Published in:
- Nucleic Acids Research, 2009, v. 37, n. 3, p. 877, doi. 10.1093/nar/gkn1007
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- Publication type:
- Article
Characterization of Parameters Required for Effective Use of Tamoxifen-Regulated Recombination.
- Published in:
- PLoS ONE, 2008, v. 3, n. 9, p. 1, doi. 10.1371/journal.pone.0003264
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- Publication type:
- Article
Calcium signalling and cell-fate choice in B cells.
- Published in:
- 2007
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- Publication type:
- journal article
Flow cytometric analysis of DNA binding and cleavage by cell surface-displayed homing endonucleases.
- Published in:
- Nucleic Acids Research, 2007, v. 35, n. 8, p. 2748, doi. 10.1093/nar/gkm182
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- Publication type:
- Article
Protein kinase D enzymes are dispensable for proliferation, survival and antigen receptor-regulated NFκB activity in vertebrate B-cells
- Published in:
- FEBS Letters, 2007, v. 581, n. 7, p. 1377, doi. 10.1016/j.febslet.2007.02.055
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- Publication type:
- Article
TRPM2 and TRPM7: channel/enzyme fusions to generate novel intracellular sensors.
- Published in:
- Pflügers Archiv: European Journal of Physiology, 2005, v. 451, n. 1, p. 220, doi. 10.1007/s00424-005-1444-0
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- Publication type:
- Article
1048. Engineering and Development of I-AniI Homing Endonucleases for Gene Correction Applications
- Published in:
- 2005
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- Publication type:
- Abstract
Dissociation of the store-operated calcium current I<sub>CRAC</sub> and the Mg-nucleotide-regulated metal ion current MagNuM.
- Published in:
- Journal of Physiology, 2002, v. 539, n. 2, p. 445, doi. 10.1113/jphysiol.2001.013361
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- Publication type:
- Article
LTRPC7 is a Mg-ATP-regulated divalent cation channel required for cell viability.
- Published in:
- Nature, 2001, v. 411, n. 6837, p. 590, doi. 10.1038/35079092
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- Publication type:
- Article
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology.
- Published in:
- Nature, 2001, v. 411, n. 6837, p. 595, doi. 10.1038/35079100
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- Publication type:
- Article
Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1.
- Published in:
- Oncogene, 1999, v. 18, n. 14, p. 2291, doi. 10.1038/sj.onc.1202552
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- Publication type:
- Article
Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P<sub>3</sub>)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals.
- Published in:
- EMBO Journal, 1998, v. 17, n. 7, p. 1961, doi. 10.1093/emboj/17.7.1961
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- Publication type:
- Article