Works by Schalkwijk, Stein

Results: 23

Normal fat mass cannot be reliably estimated in typical pharmacokinetic studies.

Published in:

European Journal of Clinical Pharmacology, 2021, v. 77, n. 5, p. 727, doi. 10.1007/s00228-020-03042-4

By:

Wasmann, Roeland E.;
Svensson, Elin M.;
Schalkwijk, Stein J.;
Brüggemann, Roger J.;
ter Heine, Rob

Publication type:

Article

Lidocaine-Associated Cardiac Events in Newborns with Seizures: Incidence, Symptoms and Contributing Factors.

Published in:

Neonatology (16617800), 2015, v. 108, n. 2, p. 130, doi. 10.1159/000430767

By:

Weeke, Lauren C.;
Schalkwijk, Stein;
Toet, Mona C.;
van Rooij, Linda G.M.;
de Vries, Linda S.;
van den Broek, Marcel P.H.

Publication type:

Article

Physiologically Based Pharmacokinetic Modeling for Selumetinib to Evaluate Drug‐Drug Interactions and Pediatric Dose Regimens.

Published in:

Journal of Clinical Pharmacology, 2021, v. 61, n. 11, p. 1493, doi. 10.1002/jcph.1935

By:

Cohen‐Rabbie, Sarit;
Zhou, Li;
Vishwanathan, Karthick;
Wild, Martin;
Xu, Sherrie;
Freshwater, Tomoko;
Jain, Lokesh;
Schalkwijk, Stein;
Tomkinson, Helen;
Zhou, Diansong

Publication type:

Article

The Impact of Dose and Simultaneous Use of Acid-Reducing Agents on the Effectiveness of Vemurafenib in Metastatic BRAF V600 Mutated Melanoma: a Retrospective Cohort Study.

Published in:

2018

By:

Knapen, Lotte M.;
Koornstra, Rutger H. T.;
Driessen, Johanna H. M.;
van Vlijmen, Bas;
Croes, Sander;
Schalkwijk, Stein;
Colbers, Angela;
Gerritsen, Winald R.;
Burger, David M.;
de Vries, Frank;
van Erp, Nielka P.

Publication type:

journal article

Evaluating darunavir/ritonavir dosing regimens for HIV-positive pregnant women using semi-mechanistic pharmacokinetic modelling.

Published in:

2019

By:

Schalkwijk, Stein;
Heine, Rob ter;
Colbers, Angela;
Capparelli, Edmund;
Best, Brookie M;
Cressey, Tim R;
Greupink, Rick;
Russel, Frans G M;
Moltó, José;
Mirochnick, Mark;
Karlsson, Mats O;
Burger, David M;
Ter Heine, Rob

Publication type:

journal article

Placental transfer of the HIV integrase inhibitor dolutegravir in an ex vivo human cotyledon perfusion model.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2016, v. 71, n. 2, p. 480, doi. 10.1093/jac/dkv358

By:

Schalkwijk, Stein;
Greupink, Rick;
Colbers, Angela P.;
Wouterse, Alfons C.;
Verweij, Vivienne G. M.;
van Drongelen, Joris;
Teulen, Marga;
van den Oetelaar, Daphne;
Burger, David M.;
Russel, Frans G. M.

Publication type:

Article

Etravirine Pharmacokinetics in HIV-Infected Pregnant Women.

Published in:

Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00239

By:

Mulligan, Nikki;
Schalkwijk, Stein;
Best, Brookie M.;
Colbers, Angela;
Wang, Jiajia;
Capparelli, Edmund V.;
Moltó, José;
Stek, Alice M.;
Taylor, Graham;
Smith, Elizabeth;
Tenorio, Carmen Hidalgo;
Chakhtoura, Nahida;
van Kasteren, Marjo;
Fletcher, Courtney V.;
Mirochnick, Mark;
Burger, David

Publication type:

Article

Importance of Prospective Studies in Pregnant and Breastfeeding Women Living With Human Immunodeficiency Virus.

Published in:

Clinical Infectious Diseases, 2019, v. 69, n. 7, p. 1254, doi. 10.1093/cid/ciz121

By:

Colbers, Angela;
Mirochnick, Mark;
Schalkwijk, Stein;
Penazzato, Martina;
Townsend, Claire;
Burger, David

Publication type:

Article

Lowered Rilpivirine Exposure During the Third Trimester of Pregnancy in Human Immunodeficiency Virus Type 1-Infected Women.

Published in:

Clinical Infectious Diseases, 2017, v. 65, n. 8, p. 1335, doi. 10.1093/cid/cix534

By:

Schalkwijk, Stein;
Colbers, Angela;
Konopnicki, Deborah;
Gingelmaier, Andrea;
Lambert, John;
van der Ende, Marchina;
Moltó, José;
Burger, David

Publication type:

Article

Maraviroc Pharmacokinetics in HIV-1-Infected Pregnant Women.

Published in:

Clinical Infectious Diseases, 2015, v. 61, n. 10, p. 1582, doi. 10.1093/cid/civ587

By:

Colbers, Angela;
Best, Brookie;
Schalkwijk, Stein;
Jiajia Wang;
Stek, Alice;
Tenorio, Carmen Hidalgo;
Hawkins, David;
Taylor, Graham;
Kreitchmann, Regis;
Burchett, Sandra;
Haberl, Annette;
Kabeya, Kabamba;
van Kasteren, Marjo;
Smith, Elizabeth;
Capparelli, Edmund;
Burger, David;
Mirochnick, Mark

Publication type:

Article

Population pharmacokinetics and exposure–response of selumetinib and its N‐desmethyl metabolite in pediatric patients with neurofibromatosis type 1 and inoperable plexiform neurofibromas.

Published in:

Cancer Chemotherapy & Pharmacology, 2021, v. 88, n. 2, p. 189, doi. 10.1007/s00280-021-04274-6

By:

Schalkwijk, Stein;
Zhou, Li;
Cohen‐Rabbie, Sarit;
Jain, Lokesh;
Freshwater, Tomoko;
So, Karen;
He, Zhongqing;
Gioni, Ioanna;
Tomkinson, Helen;
Vishwanathan, Karthick;
Zhou, Diansong

Publication type:

Article

Declining efficacy in controlled trials of antidepressants: effects of placebo dropout.

Published in:

International Journal of Neuropsychopharmacology, 2014, v. 17, n. 8, p. 1343, doi. 10.1017/S1461145714000224

By:

Schalkwijk, Stein;
Undurraga, Juan;
Tondo, Leonardo;
Baldessarini, Ross J.

Publication type:

Article

Assessment of Maternal and Fetal Dolutegravir Exposure by Integrating Ex Vivo Placental Perfusion Data and Physiologically‐Based Pharmacokinetic Modeling.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 107, n. 6, p. 1352, doi. 10.1002/cpt.1748

By:

Freriksen, Jolien J.M.;
Schalkwijk, Stein;
Colbers, Angela P.;
Abduljalil, Khaled;
Russel, Frans G.M.;
Burger, David M.;
Greupink, Rick

Publication type:

Article

Free dug concentrations in pregnancy: Bound to measure unbound?

Published in:

2017

By:

Schalkwijk, Stein;
Greupink, Rick;
Burger, David

Publication type:

Editorial

Parent and Metabolite Concentration-QT Modeling to Evaluate QT-Interval Prolongation at Savolitinib Therapeutic Doses.

Published in:

AAPS Journal, 2021, v. 23, n. 3, p. 1, doi. 10.1208/s12248-021-00573-1

By:

Schalkwijk, Stein;
Sahota, Tarjinder;
Verheijen, Remy B.;
Harmer, Alexander R.;
Ahmed, Ghada F.

Publication type:

Article

Pharmacokinetics of Depemokimab Delivered by Safety Syringe Device or Autoinjector in Healthy Adults: A Phase 1, Single‐Dose Study.

Published in:

Clinical Pharmacology in Drug Development, 2025, v. 14, n. 3, p. 190, doi. 10.1002/cpdd.1506

By:

Schalkwijk, Stein;
Zecchin, Chiara;
Sen, Anusmita;
Choi, Sei;
Wang, Kai;
Min, Jeff;
Spears, Brian

Publication type:

Article

Concentration‐QT modelling in early clinical oncology settings: Simulation evaluation of performance.

Published in:

British Journal of Clinical Pharmacology, 2022, v. 88, n. 3, p. 1010, doi. 10.1111/bcp.15047

By:

Cantet, Gael;
Berges, Alienor;
O'Sullivan, Rhianna;
Cohen‐Rabbie, Sarit;
Dota, Corina;
Dubois, Vincent;
Benoist, Guillemette E.;
Tomkinson, Helen;
Rekić, Dinko;
Parkinson, Joanna;
Schalkwijk, Stein

Publication type:

Article

Clinical evaluation of the potential drug–drug interactions of savolitinib: Interaction with rifampicin, itraconazole, famotidine or midazolam.

Published in:

British Journal of Clinical Pharmacology, 2022, v. 88, n. 2, p. 655, doi. 10.1111/bcp.14994

By:

Ren, Song;
Vishwanathan, Karthick;
Cantarini, Mireille;
Frewer, Paul;
Hara, Indira;
Scarfe, Graeme;
Burke, Wendy;
Schalkwijk, Stein;
Li, Yan;
Han, David;
Goldwater, Ronald

Publication type:

Article

Safety, tolerability, and pharmacokinetics of Aurora kinase B inhibitor AZD2811: a phase 1 dose-finding study in patients with advanced solid tumours.

Published in:

British Journal of Cancer, 2023, v. 128, n. 10, p. 1906, doi. 10.1038/s41416-023-02185-2

By:

Johnson, Melissa L.;
Wang, Judy S.;
Falchook, Gerald;
Greenlees, Carol;
Jones, Suzanne;
Strickland, Donald;
Fabbri, Giulia;
Kennedy, Caroline;
Elizabeth Pease, J.;
Sainsbury, Liz;
MacDonald, Alexander;
Schalkwijk, Stein;
Szekeres, Philip;
Cosaert, Jan;
Burris III, Howard

Publication type:

Article

Pharmacokinetics of HIV-Integrase Inhibitors During Pregnancy: Mechanisms, Clinical Implications and Knowledge Gaps.

Published in:

2019

By:

van der Galiën, Ruben;
ter Heine, Rob;
Greupink, Rick;
Schalkwijk, Stein J.;
van Herwaarden, Antonius E.;
Colbers, Angela;
Burger, David M.

Publication type:

journal article

A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women.

Published in:

2018

By:

Schalkwijk, Stein;
ter Heine, Rob;
Colbers, Angela C.;
Huitema, Alwin D. R.;
Denti, Paolo;
Dooley, Kelly E.;
Capparelli, Edmund;
Best, Brookie M.;
Cressey, Tim R.;
Greupink, Rick;
Russel, Frans G. M.;
Mirochnick, Mark;
Burger, David M.

Publication type:

journal article

Prediction of Fetal Darunavir Exposure by Integrating Human Ex-Vivo Placental Transfer and Physiologically Based Pharmacokinetic Modeling.

Published in:

2018

By:

Schalkwijk, Stein;
Buaben, Aaron O.;
Freriksen, Jolien J. M.;
Colbers, Angela P.;
Burger, David M.;
Greupink, Rick;
Russel, Frans G. M.

Publication type:

journal article

A phase 1/2 study of the combination of acalabrutinib and vistusertib in patients with relapsed/refractory B-cell malignancies.

Published in:

Leukemia & Lymphoma, 2021, v. 62, n. 11, p. 2625, doi. 10.1080/10428194.2021.1938027

By:

Collins, Graham P.;
Clevenger, Tracy N.;
Burke, Kathleen A.;
Yang, Buyue;
MacDonald, Alex;
Cunningham, David;
Fox, Christopher P.;
Goy, Andre;
Gribben, John;
Nowakowski, Grzegorz S.;
Roschewski, Mark;
Vose, Julie M.;
Vallurupalli, Anusha;
Cheung, Jean;
Raymond, Amelia;
Nuttall, Barrett;
Stetson, Dan;
Dougherty, Brian A.;
Schalkwijk, Stein;
Carnevalli, Larissa S.

Publication type:

Article