Works by Schaffer, Jean

Results: 24

A Murine Niemann-Pick C1 I1061T Knock-In Model Recapitulates the Pathological Features of the Most Prevalent Human Disease Allele.
Published in:
Journal of Neuroscience, 2015, v. 35, n. 21, p. 8091, doi. 10.1523/JNEUROSCI.4173-14.2015
By:
- Praggastis, Maria;
- Tortelli, Brett;
- Zhang, Jessie;
- Fujiwara, Hideji;
- Sidhu, Rohini;
- Chacko, Anita;
- Zhouji Chen;
- Chan Chung;
- Lieberman, Andrew P.;
- Sikora, Jakub;
- Davidson, Cristin;
- Walkley, Steven U.;
- Pipalia, Nina H.;
- Maxfield, Frederick R.;
- Schaffer, Jean E.;
- Ory, Daniel S.
Publication type:
Article
A Diet Rich in Medium-Chain Fatty Acids Improves Systolic Function and Alters the Lipidomic Profile in Patients With Type 2 Diabetes: A Pilot Study.
Published in:
2016
By:
- Airhart, Sophia;
- Cade, W Todd;
- Jiang, Hui;
- Coggan, Andrew R;
- Racette, Susan B;
- Korenblat, Kevin;
- Spearie, Catherine Anderson;
- Waller, Suzanne;
- O'Connor, Robert;
- Bashir, Adil;
- Ory, Daniel S;
- Schaffer, Jean E;
- Novak, Eric;
- Farmer, Marsha;
- Waggoner, Alan D;
- Dávila-Román, Víctor G;
- Javidan-Nejad, Cylen;
- Peterson, Linda R
Publication type:
journal article
Author Correction: Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis.
Published in:
2021
By:
- Sletten, Arthur C.;
- Davidson, Jessica W.;
- Yagabasan, Busra;
- Moores, Samantha;
- Schwaiger-Haber, Michaela;
- Fujiwara, Hideji;
- Gale, Sarah;
- Jiang, Xuntian;
- Sidhu, Rohini;
- Gelman, Susan J.;
- Zhao, Shuang;
- Patti, Gary J.;
- Ory, Daniel S.;
- Schaffer, Jean E.
Publication type:
Correction Notice
Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25457-y
By:
- Sletten, Arthur C.;
- Davidson, Jessica W.;
- Yagabasan, Busra;
- Moores, Samantha;
- Schwaiger-Haber, Michaela;
- Fujiwara, Hideji;
- Gale, Sarah;
- Jiang, Xuntian;
- Sidhu, Rohini;
- Gelman, Susan;
- Zhao, Shuang;
- Patti, Gary;
- Ory, Daniel S.;
- Schaffer, Jean E.
Publication type:
Article
Lipotoxicity in the heart.
Published in:
Current Hypertension Reports, 2005, v. 7, n. 6, p. 412, doi. 10.1007/s11906-005-0035-y
By:
- Borradaile, Nica;
- Schaffer, Jean
Publication type:
Article
ApoA-1 in Diabetes: Damaged Goods.
Published in:
2010
By:
- Ory, Daniel S.;
- Schaffer, Jean E.
Publication type:
Opinion
Ueber den Desinfectionswerth des Aethylendiaminsilberphosphats und Aethylendiaminkresols, nebst Bemerkungen über die Anwendung der Centrifuge bei Desinfectionsversuchen.
Published in:
Medical Microbiology & Immunology, 1894, v. 16, n. 1, p. 189, doi. 10.1007/BF02284414
By:
- Schäffer, Jean
Publication type:
Article
Development of a bile acid–based newborn screen for Niemann-Pick disease type C.
Published in:
Science Translational Medicine, 2016, v. 8, n. 337, p. 1, doi. 10.1126/scitranslmed.aaf2326
By:
- Xuntian Jiang;
- Sidhu, Rohini;
- Mydock-McGrane, Laurel;
- Fong-Fu Hsu;
- Covey, Douglas F.;
- Scherrer, David E.;
- Earley, Brian;
- Gale, Sarah E.;
- Farhat, Nicole Y.;
- Porter, Forbes D.;
- Dietzen, Dennis J.;
- Orsini, Joseph J.;
- Berry-Kravis, Elizabeth;
- Xiaokui Zhang;
- Reunert, Janice;
- Marquardt, Thorsten;
- Runz, Heiko;
- Giugliani, Roberto;
- Schaffer, Jean E.;
- Ory, Daniel S.
Publication type:
Article
Cholesterol Oxidation Products Are Sensitive and Specific Blood-Based Biomarkers for Niemann-Pick C1 Disease.
Published in:
Science Translational Medicine, 2010, v. 2, n. 56, p. 1, doi. 10.1126/scitranslmed.3001417
By:
- Porter, Forbes D.;
- Scherrer, David E.;
- Lanier, Michael H.;
- Langmade, S. Joshua;
- Molugu, Vasumathi;
- Gale, Sarah E.;
- Olzeski, Dana;
- Sidhu, Rohini;
- Dietzen, Dennis J.;
- Rao Fu;
- Wassif, Christopher A.;
- Yanjanin, Nicole M.;
- Marso, Steven P.;
- House, John;
- Vite, Charles;
- Schaffer, Jean E.;
- Ory, Daniel S.
Publication type:
Article
Death by Lipids: role of noncoding RNAs in metabolic stress.
Published in:
FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.00042
By:
- Schaffer, Jean
Publication type:
Article
Ceramide Remodeling and Risk of Cardiovascular Events and Mortality.
Published in:
2018
By:
- Peterson, Linda R.;
- Xanthakis, Vanessa;
- Duncan, Meredith S.;
- Gross, Stefan;
- Friedrich, Nele;
- Völzke, Henry;
- Felix, Stephan B.;
- Hui Jiang;
- Sidhu, Rohini;
- Nauck, Matthias;
- Xuntian Jiang;
- Ory, Daniel S.;
- Dörr, Marcus;
- Vasan, Ramachandran S.;
- Schaffer, Jean E.;
- Jiang, Hui;
- Jiang, Xuntian
Publication type:
journal article
The Association Between C24:0/C16:0 Ceramide Ratio and Cardiorespiratory Fitness is Robust to Effect Modifications by Age and Sex.
Published in:
Advanced Biology, 2024, v. 8, n. 4, p. 1, doi. 10.1002/adbi.202300633
By:
- Zatloukal, Jule;
- Zylla, Stephanie;
- Markus, Marcello R.P.;
- Ewert, Ralf;
- Gläser, Sven;
- Völzke, Henry;
- Albrecht, Diana;
- Friedrich, Nele;
- Nauck, Matthias;
- Peterson, Linda R.;
- Jiang, Xuntian;
- Schaffer, Jean E.;
- Felix, Stephan B.;
- Dörr, Marcus;
- Bahls, Martin;
- Gross, Stefan
Publication type:
Article
Bariatric Surgery-Induced Cardiac and Lipidomic Changes in Obesity-Related Heart Failure with Preserved Ejection Fraction.
Published in:
2018
By:
- Mikhalkova, Deana;
- Holman, Sujata R.;
- Jiang, Hui;
- Saghir, Mohammed;
- Novak, Eric;
- Coggan, Andrew R.;
- O'Connor, Robert;
- Bashir, Adil;
- Jamal, Ali;
- Ory, Daniel S.;
- Schaffer, Jean E.;
- Eagon, J. Christopher;
- Peterson, Linda R.;
- O'Connor, Robert
Publication type:
journal article
FACL4, encoding fatty acid-CoA ligase 4, is mutated in nonspecific X-linked mental retardation.
Published in:
Nature Genetics, 2002, v. 30, n. 4, p. 436, doi. 10.1038/ng857
By:
- Meloni, Ilaria;
- Muscettola, Maddalena;
- Raynaud, Martine;
- Longo, Ilaria;
- Bruttini, Mirella;
- Moizard, Marie-Pierre;
- Gomot, Marie;
- Chelly, Jamel;
- des Portes, Vincent;
- Fryns, Jean-Pierre;
- Ropers, Hans-Hilger;
- Magi, Barbara;
- Bellan, Cristina;
- Volpi, Nila;
- Yntema, Helger G.;
- Lewis, Sarah E.;
- Schaffer, Jean E.;
- Renieri, Alessandra
Publication type:
Article
Development and validation of LC-MS/MS method for determination of very long acyl chain (C22:0 and C24:0) ceramides in human plasma.
Published in:
Analytical & Bioanalytical Chemistry, 2013, v. 405, n. 23, p. 7357, doi. 10.1007/s00216-013-7166-9
By:
- Jiang, Hui;
- Hsu, Fong-Fu;
- Farmer, Marsha;
- Peterson, Linda;
- Schaffer, Jean;
- Ory, Daniel;
- Jiang, Xuntian
Publication type:
Article
Cholesterol homeostatic responses provide biomarkers for monitoring treatment for the neurodegenerative disease Niemann–Pick C1 (NPC1).
Published in:
Human Molecular Genetics, 2014, v. 23, n. 22, p. 6022, doi. 10.1093/hmg/ddu331
By:
- Tortelli, Brett;
- Fujiwara, Hideji;
- Bagel, Jessica H.;
- Zhang, Jessie;
- Sidhu, Rohini;
- Jiang, Xuntian;
- Yanjanin, Nicole M.;
- Shankar, Roopa Kanakatti;
- Carillo-Carasco, Nuria;
- Heiss, John;
- Ottinger, Elizabeth;
- Porter, Forbes D.;
- Schaffer, Jean E.;
- Vite, Charles H.;
- Ory, Daniel S.
Publication type:
Article
Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking.
Published in:
2008
By:
- Zhang, Jessie R.;
- Coleman, Trey;
- Langmade, S. Joshua;
- Scherrer, David E.;
- Lane, Lindsay;
- Lanier, M. Hunter;
- Chu Feng;
- Sands, Mark S.;
- Schaffer, Jean E.;
- Semenkovich, Clay F.;
- Ory, Daniel S.;
- Feng, Chu
Publication type:
journal article
A HILIC‐MS/MS method for simultaneous quantification of the lysosomal disease markers galactosylsphingosine and glucosylsphingosine in mouse serum.
Published in:
Biomedical Chromatography, 2018, v. 32, n. 7, p. 1, doi. 10.1002/bmc.4235
By:
- Sidhu, Rohini;
- Mikulka, Christina R.;
- Fujiwara, Hideji;
- Sands, Mark S.;
- Schaffer, Jean E.;
- Ory, Daniel S.;
- Jiang, Xuntian
Publication type:
Article
Gonorrhea Rates: What Denominator is Most Appropriate?
Published in:
American Journal of Public Health, 1988, v. 78, n. 6, p. 702, doi. 10.2105/AJPH.78.6.702
By:
- Aral, Sevgi O.;
- Schaffer, Jean E.;
- Mosher, William D.;
- Cates Jr., Willard
Publication type:
Article
P3‐253: PLASMA CERAMIDES AND RISK OF DEMENTIA.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1033, doi. 10.1016/j.jalz.2019.06.3284
By:
- McGrath, Emer R.;
- Himali, Jayandra J.;
- Xanthakis, Vanessa;
- Duncan, Meredith S.;
- Schaffer, Jean E.;
- Ory, Daniel S.;
- Peterson, Linda R.;
- DeCarli, Charlie S.;
- Pase, Matthew P.;
- Satizabal, Claudia L.;
- Vasan, Ramachandran S.;
- Beiser, Alexa S.;
- Seshadri, Sudha
Publication type:
Article
Circulating ceramide ratios and risk of vascular brain aging and dementia.
Published in:
Annals of Clinical & Translational Neurology, 2020, v. 7, n. 2, p. 160, doi. 10.1002/acn3.50973
By:
- McGrath, Emer R.;
- Himali, Jayandra J.;
- Xanthakis, Vanessa;
- Duncan, Meredith S.;
- Schaffer, Jean E.;
- Ory, Daniel S.;
- Peterson, Linda R.;
- DeCarli, Charles;
- Pase, Matthew P.;
- Satizabal, Claudia L.;
- Vasan, Ramachandran S.;
- Beiser, Alexa S.;
- Seshadri, Sudha
Publication type:
Article
RNA Regulation of Lipotoxicity and Metabolic Stress.
Published in:
2016
By:
- Caputa, George;
- Schaffer, Jean E.
Publication type:
journal article
Plasma Sphingolipids Associated with Chronic Obstructive Pulmonary Disease Phenotypes.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2015, v. 191, n. 3, p. 275, doi. 10.1164/rccm.201410-1771OC
By:
- Bowler, Russell P.;
- Jacobson, Sean;
- Cruickshank, Charmion;
- Hughes, Grant J.;
- Siska, Charlotte;
- Ory, Daniel S.;
- Petrache, Irina;
- Schaffer, Jean E.;
- Reisdorph, Nichole;
- Kechris, Katerina
Publication type:
Article
SmD3 Regulates Intronic Noncoding RNA Biogenesis.
Published in:
Molecular & Cellular Biology, 2012, v. 32, n. 20, p. 4092, doi. 10.1128/MCB.00022-12
By:
- Scruggs, Benjamin S.;
- Michel, Carlos I.;
- Ory, Daniel S.;
- Schaffer, Jean E.
Publication type:
Article