Works by Schönbrunn, Ernst

Results: 15

Comparative X-ray analysis of the un-liganded fosfomycin-target MurA.

Published in:

Proteins, 2000, v. 40, n. 2, p. 290, doi. 10.1002/(SICI)1097-0134(20000801)40:2<290::AID-PROT90>3.0.CO;2-0

By:

Eschenburg, Susanne;
Schönbrunn, Ernst

Publication type:

Article

Identification and Screening of Selective WEE2 Inhibitors to Develop Non‐Hormonal Contraceptives that Specifically Target Meiosis.

Published in:

ChemistrySelect, 2019, v. 4, n. 45, p. 13363, doi. 10.1002/slct.201903696

By:

Hanna, Carol B.;
Yao, Shan;
Martin, Mat;
Schönbrunn, Ernst;
Georg, Gunda I.;
Jensen, Jeffrey T.;
Cuellar, Rebecca A. D.

Publication type:

Article

Differential antibacterial properties of the MurA inhibitors terreic acid and fosfomycin.

Published in:

Journal of Basic Microbiology, 2014, v. 54, n. 4, p. 322, doi. 10.1002/jobm.201200617

By:

Olesen, Sanne H.;
Ingles, Donna J.;
Yang, Yan;
Schönbrunn, Ernst

Publication type:

Article

How the mutation glycine96 to alanine confers glyphosate insensitivity to 5-enolpyruvyl shikimate-3-phosphate synthase from Escherichia coli.

Published in:

Planta: An International Journal of Plant Biology, 2002, v. 216, n. 1, p. 129, doi. 10.1007/s00425-002-0908-0

By:

Eschenburg, Susanne;
Healy, Martha L.;
Priestman, Melanie A.;
Lushington, Gerald H.;
Schönbrunn, Ernst

Publication type:

Article

Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38732-x

By:

Faber, Erik B.;
Sun, Luxin;
Tang, Jian;
Roberts, Emily;
Ganeshkumar, Sornakala;
Wang, Nan;
Rasmussen, Damien;
Majumdar, Abir;
Hirsch, Laura E.;
John, Kristen;
Yang, An;
Khalid, Hira;
Hawkinson, Jon E.;
Levinson, Nicholas M.;
Chennathukuzhi, Vargheese;
Harki, Daniel A.;
Schönbrunn, Ernst;
Georg, Gunda I.

Publication type:

Article

Molecular basis for the glyphosate-insensitivity of the reaction of 5-enolpyruvylshikimate 3-phosphate synthase with shikimate

Published in:

FEBS Letters, 2005, v. 579, n. 25, p. 5773, doi. 10.1016/j.febslet.2005.09.066

By:

Priestman, Melanie A.;
Healy, Martha L.;
Funke, Todd;
Becker, Andreas;
Schönbrunn, Ernst

Publication type:

Article

5-Enolpyruvylshikimate-3-phosphate synthase from Staphylococcus aureus is insensitive to glyphosate

Published in:

FEBS Letters, 2005, v. 579, n. 3, p. 728, doi. 10.1016/j.febslet.2004.12.057

By:

Priestman, Melanie A.;
Funke, Todd;
Singh, Inder M.;
Crupper, Scott S.;
Schönbrunn, Ernst

Publication type:

Article

MurA as a Primary Target of Tulipalin B and 6-Tuliposide B.

Published in:

Bioscience, Biotechnology & Biochemistry, 2013, v. 77, n. 12, p. 2517, doi. 10.1271/bbb.130663

By:

Kengo SHIGETOMI;
OLESEN, Sanne Harder;
Yan YANG;
Shinya MITSUHASHI;
SCHÖNBRUNN, Ernst;
Makoto UBUKATA

Publication type:

Article

A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2.

Published in:

ChemBioChem, 2012, v. 13, n. 14, p. 2128, doi. 10.1002/cbic.201200316

By:

Martin, Mathew P.;
Alam, Riazul;
Betzi, Stephane;
Ingles, Donna J.;
Zhu, Jin-Yi;
Schönbrunn, Ernst

Publication type:

Article

Structure-Activity Studies of N-Butyl-1-deoxynojirimycin ( NB-DNJ) Analogues: Discovery of Potent and Selective Aminocyclopentitol Inhibitors of GBA1 and GBA2.

Published in:

ChemMedChem, 2017, v. 12, n. 23, p. 1977, doi. 10.1002/cmdc.201700558

By:

Gu, Xingxian;
Gupta, Vijayalaxmi;
Yang, Yan;
Zhu, Jin‐Yi;
Carlson, Erick J.;
Kingsley, Carolyn;
Tash, Joseph S.;
Schönbrunn, Ernst;
Hawkinson, Jon;
Georg, Gunda I.

Publication type:

Article

Discovery of Diverse Small-Molecule Inhibitors of Mammalian Sterile20-like Kinase 3 (MST3).

Published in:

ChemMedChem, 2016, v. 11, n. 11, p. 1137, doi. 10.1002/cmdc.201600115

By:

Olesen, Sanne H.;
Zhu, Jin‐Yi;
Martin, Mathew P.;
Schönbrunn, Ernst

Publication type:

Article

1,4‐Dihydropyridinebutyrolactone‐derived ring‐opened ester and amide analogs targeting BET bromodomains.

Published in:

Archiv der Pharmazie, 2022, v. 355, n. 11, p. 1, doi. 10.1002/ardp.202200288

By:

Jiang, Jiewei;
Zhao, Pei‐Liang;
Sigua, Logan H.;
Chan, Alice;
Schönbrunn, Ernst;
Qi, Jun;
Georg, Gunda I.

Publication type:

Article

Stability of the Human Hsp90-p50<sup>Cdc37</sup> Chaperone Complex against Nucleotides and Hsp90 Inhibitors, and the Influence of Phosphorylation by Casein Kinase 2.

Published in:

Molecules, 2015, v. 20, n. 1, p. 1643, doi. 10.3390/molecules20011643

By:

Olesen, Sanne H.;
Ingles, Donna J.;
Jin-Yi Zhu;
Martin, Mathew P.;
Betzi, Stephane;
Georg, Gunda I.;
Tash, Joseph S.;
Schönbrunn, Ernst

Publication type:

Article

Ack1 Mediated AKT/PKB Tyrosine 176 Phosphorylation Regulates Its Activation.

Published in:

PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009646

By:

Mahajan, Kiran;
Coppola, Domenico;
Challa, Sridevi;
Bin Fang;
Chen, Y. Ann;
Weiwei Zhu;
Lopez, Alexis S.;
Koomen, John;
Engelman, Robert W.;
Rivera, Charlene;
Muraoka-Cook, Rebecca S.;
Cheng, Jin Q.;
Schönbrunn, Ernst;
Sebti, Said M.;
Earp, H. Shelton;
Mahajan, Nupam P.

Publication type:

Article

Dihydropyridine Lactam Analogs Targeting BET Bromodomains.

Published in:

ChemMedChem, 2022, v. 17, n. 1, p. 1, doi. 10.1002/cmdc.202100407

By:

Jiang, Jiewei;
Sigua, Logan H.;
Chan, Alice;
Kalra, Prakriti;
Pomerantz, William C.K.;
Schönbrunn, Ernst;
Qi, Jun;
Georg, Gunda I.

Publication type:

Article