Works matching AU Scannevin, Robert

Results: 14

Patient-derived three-dimensional cortical neurospheres to model Parkinson's disease.

Published in:

PLoS ONE, 2022, v. 17, n. 12, p. 1, doi. 10.1371/journal.pone.0277532

By:

Raja, Waseem K.;
Neves, Esther;
Burke, Christopher;
Jiang, Xin;
Xu, Ping;
Rhodes, Kenneth J.;
Khurana, Vikram;
Scannevin, Robert H.;
Chung, Chee Yeun

Publication type:

Article

Dimethyl fumarate impairs differentiated B cells and fosters central nervous system integrity in treatment of multiple sclerosis.

Published in:

Brain Pathology, 2019, v. 29, n. 5, p. 640, doi. 10.1111/bpa.12711

By:

Traub, Jan;
Traffehn, Sarah;
Ochs, Jasmin;
Häusser‐Kinzel, Silke;
Stephan, Schirin;
Scannevin, Robert;
Brück, Wolfgang;
Metz, Imke;
Weber, Martin S.

Publication type:

Article

Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2018, v. 38, n. 8, p. 1354, doi. 10.1177/0271678X17713105

By:

Fowler, Jill H.;
McQueen, Jamie;
Holland, Philip R.;
Manso, Yasmina;
Marangoni, Martina;
Scott, Fiona;
Chisholm, Emma;
Scannevin, Robert H.;
Hardingham, Giles E.;
Horsburgh, Karen

Publication type:

Article

Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31680-3

By:

Lin, Edward Y. S.;
Silvian, Laura F.;
Marcotte, Douglas J.;
Banos, Charles C.;
Jow, Flora;
Chan, Timothy R.;
Arduini, Robert M.;
Qian, Fang;
Baker, Darren P.;
Bergeron, Chris;
Hession, Catherine A.;
Huganir, Richard L.;
Borenstein, Cassandra F.;
Enyedy, Istvan;
Zou, Jinming;
Rohde, Ellen;
Wittmann, Marion;
Kumaravel, Gnanasambandam;
Rhodes, Kenneth J.;
Scannevin, Robert H.

Publication type:

Article

Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2.

Published in:

Nature Communications, 2015, v. 6, n. 5, p. 7066, doi. 10.1038/ncomms8066

By:

Bell, Karen F.S.;
Al-Mubarak, Bashayer;
Martel, Marc-André;
McKay, Sean;
Wheelan, Nicola;
Hasel, Philip;
Márkus, Nóra M.;
Baxter, Paul;
Deighton, Ruth F.;
Serio, Andrea;
Bilican, Bilada;
Chowdhry, Sudhir;
Meakin, Paul J.;
Ashford, Michael L.J.;
Wyllie, David J.A.;
Scannevin, Robert H.;
Chandran, Siddharthan;
Hayes, John D.;
Hardingham, Giles E.

Publication type:

Article

Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS.

Published in:

Acta Neuropathologica, 2015, v. 130, n. 2, p. 279, doi. 10.1007/s00401-015-1422-3

By:

Parodi, Benedetta;
Rossi, Silvia;
Morando, Sara;
Cordano, Christian;
Bragoni, Alberto;
Motta, Caterina;
Usai, Cesare;
Wipke, Brian;
Scannevin, Robert;
Mancardi, Giovanni;
Centonze, Diego;
Kerlero de Rosbo, Nicole;
Uccelli, Antonio

Publication type:

Article

POSTSYNAPTIC ORGANIZATION AND REGULATION OF EXCITATORY SYNAPSES.

Published in:

Nature Reviews Neuroscience, 2000, v. 1, n. 2, p. 133, doi. 10.1038/35039075

By:

Scannevin, Robert H.;
Huganir, Richard L.

Publication type:

Article

BG-12 (dimethyl fumarate): a review of mechanism of action, efficacy, and safety.

Published in:

Current Medical Research & Opinion, 2014, v. 30, n. 2, p. 251, doi. 10.1185/03007995.2013.849236

By:

Fox, Robert J.;
Kita, Mariko;
Cohan, Stanley L.;
Henson, Lily Jung;
Zambrano, Javier;
Scannevin, Robert H.;
O'Gorman, John;
Novas, Mark;
Dawson, Katherine T.;
Phillips, J. Theodore

Publication type:

Article

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.

Published in:

Brain: A Journal of Neurology, 2011, v. 134, n. 3, p. 678, doi. 10.1093/brain/awq386

By:

Linker, Ralf A.;
Lee, De-Hyung;
Ryan, Sarah;
van Dam, Anne M.;
Conrad, Rebecca;
Bista, Pradeep;
Zeng, Weike;
Hronowsky, Xiaoping;
Buko, Alex;
Chollate, Sowmya;
Ellrichmann, Gisa;
Brück, Wolfgang;
Dawson, Kate;
Goelz, Susan;
Wiese, Stefan;
Scannevin, Robert H.;
Lukashev, Matvey;
Gold, Ralf

Publication type:

Article

Dimethyl Fumarate and Monoethyl Fumarate Exhibit Differential Effects on KEAP1, NRF2 Activation, and Glutathione Depletion In Vitro.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0120254

By:

Brennan, Melanie S.;
Matos, Maria F.;
Li, Bing;
Hronowski, Xiaoping;
Gao, Benbo;
Juhasz, Peter;
Rhodes, Kenneth J.;
Scannevin, Robert H.

Publication type:

Article

Non-clinical Pharmacology of YTX-7739: a Clinical Stage Stearoyl-CoA Desaturase Inhibitor Being Developed for Parkinson's Disease.

Published in:

Molecular Neurobiology, 2022, v. 59, n. 4, p. 2171, doi. 10.1007/s12035-021-02695-1

By:

Tardiff, Daniel F.;
Lucas, Matthew;
Wrona, Iwona;
Chang, Belle;
Chung, Chee Yeun;
Le Bourdonnec, Bertrand;
Rhodes, Kenneth J.;
Scannevin, Robert H.

Publication type:

Article

SEVERE CEREBRAL HYPOPERFUSION INDUCES A DEFICIT IN WHITE MATTER FUNCTION THAT IS ATTENUATED BY MODULATING MICROGLIA WITH DIMETHYL FUMARATE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1302, doi. 10.1016/j.jalz.2017.06.1985

By:

Fowler, Jill Helen;
McQueen, Jamie;
Holland, Philip R.;
Manso, Yasmina;
Marangoni, Martina;
Scott, Fiona;
Chisholm, Emma;
Scannevin, Robert;
Hardingham, Giles;
Horsburgh, Karen

Publication type:

Article

The NRF2 transcriptional target, OSGIN1, contributes to monomethyl fumarate-mediated cytoprotection in human astrocytes.

Published in:

Scientific Reports, 2017, p. 42054, doi. 10.1038/srep42054

By:

Brennan, Melanie S.;
Matos, Maria F.;
Richter, Karl E.;
Li, Bing;
Scannevin, Robert H.

Publication type:

Article

Synapto-depressive effects of amyloid beta require PICK1.

Published in:

European Journal of Neuroscience, 2014, v. 39, n. 7, p. 1225, doi. 10.1111/ejn.12499

By:

Alfonso, Stephanie;
Kessels, Helmut W.;
Banos, Charles C.;
Chan, Timothy R.;
Lin, Edward T.;
Kumaravel, Gnanasambandam;
Scannevin, Robert H.;
Rhodes, Kenneth J.;
Huganir, Richard;
Guckian, Kevin M.;
Dunah, Anthone W.;
Malinow, Roberto

Publication type:

Article