Works by Savai, Rajkumar

Results: 82
    1

    Echocardiographic Measure of Right Ventricular–Pulmonary Arterial Coupling Predicts Survival in Lung Cancer.

    Published in:
    Annals of the American Thoracic Society, 2025, v. 22, n. 7, p. 1071, doi. 10.1513/AnnalsATS.202409-949OC
    By:
    • Rako, Zvonimir A.;
    • Cekay, Michael;
    • Yogeswaran, Athiththan;
    • Yildiz, Selin;
    • Arndt, Philipp F.;
    • Kremer, Nils;
    • Schäfer, Simon;
    • Janetzko, Patrick;
    • Thal, Bruno R.;
    • Mummert, Chris M.;
    • Franken, Johanna K.;
    • Soethe, Henrik;
    • Werner, Hannah F.;
    • Dumitrascu, Rio;
    • Grimminger, Friedrich;
    • Ghofrani, Hossein A.;
    • Pullamsetti, Soni S.;
    • Seeger, Werner;
    • Naeije, Robert;
    • Savai, Rajkumar
    Publication type:
    Article
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    The Role of Dimethylarginine Dimethylaminohydrolase in Idiopathic Pulmonary Fibrosis.

    Published in:
    Science Translational Medicine, 2011, v. 3, n. 87, p. 1, doi. 10.1126/scitranslmed.3001725
    By:
    • Pullamsetti, Soni Savai;
    • Savai, Rajkumar;
    • Dumitrascu, Rio;
    • Dahal, Bhola Kumar;
    • Wilhelm, Jochen;
    • Konigshoff, Melanie;
    • Zakrzewicz, Dariusz;
    • Ghofrani, Hossein Ardeschir;
    • Weissmann, Norbert;
    • Eickelberg, Oliver;
    • Guenther, Andreas;
    • Leiper, James;
    • Seeger, Werner;
    • Grimminger, Friedrich;
    • Schermuly, Ralph Theo
    Publication type:
    Article
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    Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: Multilayered cross-talks in the setting of coinfections and comorbidities.

    Published in:
    2023
    By:
    • Kumar, Rahul;
    • Aktay-Cetin, Öznur;
    • Craddock, Vaughn;
    • Morales-Cano, Daniel;
    • Kosanovic, Djuro;
    • Cogolludo, Angel;
    • Perez-Vizcaino, Francisco;
    • Avdeev, Sergey;
    • Kumar, Ashok;
    • Ram, Anil Kumar;
    • Agarwal, Stuti;
    • Chakraborty, Ananya;
    • Savai, Rajkumar;
    • de Jesus Perez, Vinicio;
    • Graham, Brian B.;
    • Butrous, Ghazwan;
    • Dhillon, Navneet K.
    Publication type:
    Literature Review
    11

    HIV and Schistosoma Co-Exposure Leads to Exacerbated Pulmonary Endothelial Remodeling and Dysfunction Associated with Altered Cytokine Landscape.

    Published in:
    Cells (2073-4409), 2022, v. 11, n. 15, p. 2414, doi. 10.3390/cells11152414
    By:
    • Medrano-Garcia, Sandra;
    • Morales-Cano, Daniel;
    • Barreira, Bianca;
    • Vera-Zambrano, Alba;
    • Kumar, Rahul;
    • Kosanovic, Djuro;
    • Schermuly, Ralph Theo;
    • Graham, Brian B.;
    • Perez-Vizcaino, Francisco;
    • Mathie, Alistair;
    • Savai, Rajkumar;
    • Pullamseti, Soni;
    • Butrous, Ghazwan;
    • Fernández-Malavé, Edgar;
    • Cogolludo, Angel
    Publication type:
    Article
    12

    Association of Clonal Hematopoiesis of Indeterminate Potential with Inflammatory Gene Expression in Patients with COPD.

    Published in:
    Cells (2073-4409), 2022, v. 11, n. 13, p. N.PAG, doi. 10.3390/cells11132121
    By:
    • Kuhnert, Stefan;
    • Mansouri, Siavash;
    • Rieger, Michael A.;
    • Savai, Rajkumar;
    • Avci, Edibe;
    • Díaz-Piña, Gabriela;
    • Padmasekar, Manju;
    • Looso, Mario;
    • Hadzic, Stefan;
    • Acker, Till;
    • Klatt, Stephan;
    • Wilhelm, Jochen;
    • Fleming, Ingrid;
    • Sommer, Natascha;
    • Weissmann, Norbert;
    • Vogelmeier, Claus;
    • Bals, Robert;
    • Zeiher, Andreas;
    • Dimmeler, Stefanie;
    • Seeger, Werner
    Publication type:
    Article
    13

    Fibroblast Growth Factor—14 Acts as Tumor Suppressor in Lung Adenocarcinomas.

    Published in:
    Cells (2073-4409), 2020, v. 9, n. 8, p. 1755, doi. 10.3390/cells9081755
    By:
    • Turkowski, Kati;
    • Herzberg, Frederik;
    • Günther, Stefan;
    • Brunn, David;
    • Weigert, Andreas;
    • Meister, Michael;
    • Muley, Thomas;
    • Kriegsmann, Mark;
    • Schneider, Marc A.;
    • Winter, Hauke;
    • Thomas, Michael;
    • Grimminger, Friedrich;
    • Seeger, Werner;
    • Savai Pullamsetti, Soni;
    • Savai, Rajkumar
    Publication type:
    Article
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    Premalignant Progression in the Lung: Knowledge Gaps and Novel Opportunities for Interception of Non–Small Cell Lung Cancer. An Official American Thoracic Society Research Statement.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2024, v. 210, n. 5, p. 548, doi. 10.1164/rccm.202406-1168ST
    By:
    • Moghaddam, Seyed Javad;
    • Savai, Rajkumar;
    • Salehi-Rad, Ramin;
    • Sengupta, Shreoshi;
    • Kammer, Michael N.;
    • Massion, Pierre;
    • Beane, Jennifer E.;
    • Ostrin, Edwin J.;
    • Priolo, Carmen;
    • Tennis, Meredith A.;
    • Stabile, Laura P.;
    • Bauer, Alison K.;
    • Sears, Catherine R.;
    • Szabo, Eva;
    • Rivera, M. Patricia;
    • Powell, Charles A.;
    • Kadara, Humam;
    • Jenkins, Brendan J.;
    • Dubinett, Steven M.;
    • Houghton, A. McGarry
    Publication type:
    Article
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    Reply to Zheng .

    Published in:
    2021
    By:
    • Eul, Bastian;
    • Cekay, Michael;
    • Tello, Khodr;
    • Wilhelm, Jochen;
    • Gattenlöhner, Stefan;
    • Sibelius, Ulf;
    • Grimminger, Friedrich;
    • Seeger, Werner;
    • Pullamsetti, Soni Savai;
    • Savai, Rajkumar
    Publication type:
    Letter to the Editor
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    Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase.

    Published in:
    Molecular Cancer, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12943-022-01661-2
    By:
    • Merle, Nastasja;
    • Elmshäuser, Sabrina;
    • Strassheimer, Florian;
    • Wanzel, Michael;
    • König, Alexander M.;
    • Funk, Julianne;
    • Neumann, Michelle;
    • Kochhan, Katharina;
    • Helmprobst, Frederik;
    • Pagenstecher, Axel;
    • Nist, Andrea;
    • Mernberger, Marco;
    • Schneider, André;
    • Braun, Thomas;
    • Borggrefe, Tilman;
    • Savai, Rajkumar;
    • Timofeev, Oleg;
    • Stiewe, Thorsten
    Publication type:
    Article
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    Reversal of experimental pulmonary hypertension by PDGF inhibition.

    Published in:
    Journal of Clinical Investigation, 2005, v. 115, n. 10, p. 2811, doi. 10.1172/JCI24838
    By:
    • Schermuly, Ralph Theo;
    • Dony, Eva;
    • Ghofrani, Hossein Ardeschir;
    • Pullamsetti, Soni;
    • Savai, Rajkumar;
    • Roth, Markus;
    • Sydykov, Akylbek;
    • Ying Ju Lai;
    • Weissmann, Norbert;
    • Seeger, Werner;
    • Grimminger, Friedrich
    Publication type:
    Article
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    Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system.

    Published in:
    Nature Communications, 2022, v. 13, p. 1, doi. 10.1038/s41467-022-33458-8
    By:
    • Weigert, Andreas;
    • Zheng, Xiang;
    • Nenzel, Alina;
    • Turkowski, Kati;
    • Günther, Stefan;
    • Strack, Elisabeth;
    • Sirait-Fischer, Evelyn;
    • Elwakeel, Eiman;
    • Kur, Ivan M.;
    • Nikam, Vandana S.;
    • Valasarajan, Chanil;
    • Winter, Hauke;
    • Wissgott, Alexander;
    • Voswinkel, Robert;
    • Grimminger, Friedrich;
    • Brüne, Bernhard;
    • Seeger, Werner;
    • Pullamsetti, Soni Savai;
    • Savai, Rajkumar
    Publication type:
    Article
    35

    Lung cancer-associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell-immune cell cross-talk.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 416, p. 1, doi. 10.1126/scitranslmed.aai9048
    By:
    • Pullamsetti, Soni Savai;
    • Kojonazarov, Baktybek;
    • Storn, Samantha;
    • Gall, Henning;
    • Salazar, Ylia;
    • Wolf, Janine;
    • Weigert, Andreas;
    • El-Nikhely, Nefertiti;
    • Ghofrani, Hossein Ardeschir;
    • Krombach, Gabriele A.;
    • Fink, Ludger;
    • Gattenlöhner, Stefan;
    • Rapp, Ulf R.;
    • Schermuly, Ralph Theo;
    • Grimminger, Friedrich;
    • Seeger, Werner;
    • Savai, Rajkumar
    Publication type:
    Article
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    Immune and Inflammatory Cell Involvement in the Pathology of Idiopathic Pulmonary Arterial Hypertension.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2012, v. 186, n. 9, p. 897, doi. 10.1164/rccm.201202-0335OC
    By:
    • Savai, Rajkumar;
    • Pullamsetti, Soni S.;
    • Kolbe, Julia;
    • Bieniek, Ewa;
    • Voswinckel, Robert;
    • Fink, Ludger;
    • Scheed, Axel;
    • Ritter, Christin;
    • Dahal, Bhola K.;
    • Vater, Axel;
    • Klussmann, Sven;
    • Ghofrani, Hossein A.;
    • Weissmann, Norbert;
    • Klepetko, Walter;
    • Banat, Gamal A.;
    • Seeger, Werner;
    • Grimminger, Friedrich;
    • Schermuly, Ralph T.
    Publication type:
    Article
    38

    Inhibition of MicroRNA-17 Improves Lung and Heart Function in Experimental Pulmonary Hypertension.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2012, v. 185, n. 4, p. 409, doi. 10.1164/rccm.201106-1093OC
    By:
    • Pullamsetti, Soni S.;
    • Doebele, Carmen;
    • Fischer, Ariane;
    • Savai, Rajkumar;
    • Kojonazarov, Baktybek;
    • Daha, Bhola K.;
    • Ghofran, Hossein A.;
    • Weissmann, Norbert;
    • Grimminger, Friedrich;
    • Bonauer, Angelika;
    • Seeger, Werner;
    • Zeiher, Andreas M.;
    • Dimmeler, Stefanie;
    • Schermuly, Ralph T.
    Publication type:
    Article
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    The Multi-Modal Effect of the Anti-fibrotic Drug Pirfenidone on NSCLC.

    Published in:
    Frontiers in Oncology, 2020, v. 9, p. 1, doi. 10.3389/fonc.2019.01550
    By:
    • Marwitz, Sebastian;
    • Turkowski, Kati;
    • Nitschkowski, Dörte;
    • Weigert, Andreas;
    • Brandenburg, Julius;
    • Reiling, Norbert;
    • Thomas, Michael;
    • Reck, Martin;
    • Drömann, Daniel;
    • Seeger, Werner;
    • Rabe, Klaus F.;
    • Savai, Rajkumar;
    • Goldmann, Torsten
    Publication type:
    Article
    42

    Interferon Regulatory Factor 9 Promotes Lung Cancer Progression via Regulation of Versican.

    Published in:
    Cancers, 2021, v. 13, n. 2, p. 208, doi. 10.3390/cancers13020208
    By:
    • Brunn, David;
    • Turkowski, Kati;
    • Günther, Stefan;
    • Weigert, Andreas;
    • Muley, Thomas;
    • Kriegsmann, Mark;
    • Winter, Hauke;
    • Dammann, Reinhard H.;
    • Stathopoulos, Georgios T.;
    • Thomas, Michael;
    • Guenther, Andreas;
    • Grimminger, Friedrich;
    • Pullamsetti, Soni S.;
    • Seeger, Werner;
    • Savai, Rajkumar
    Publication type:
    Article
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    Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate.

    Published in:
    EMBO Molecular Medicine, 2016, v. 8, n. 12, p. 1380, doi. 10.15252/emmm.201606382
    By:
    • Mehta, Aditi;
    • Cordero, Julio;
    • Dobersch, Stephanie;
    • Romero‐Olmedo, Addi J;
    • Savai, Rajkumar;
    • Bodner, Johannes;
    • Chao, Cho‐Ming;
    • Fink, Ludger;
    • Guzmán‐Díaz, Ernesto;
    • Singh, Indrabahadur;
    • Dobreva, Gergana;
    • Rapp, Ulf R;
    • Günther, Stefan;
    • Ilinskaya, Olga N;
    • Bellusci, Saverio;
    • Dammann, Reinhard H;
    • Braun, Thomas;
    • Seeger, Werner;
    • Gattenlöhner, Stefan;
    • Tresch, Achim
    Publication type:
    Article
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    Endotoxin induces proliferation of NSCLC in vitro and in vivo: role of COX-2 and EGFR activation.

    Published in:
    Cancer Immunology, Immunotherapy, 2013, v. 62, n. 2, p. 309, doi. 10.1007/s00262-012-1341-2
    By:
    • Hattar, Katja;
    • Savai, Rajkumar;
    • Subtil, Florentine;
    • Wilhelm, Jochen;
    • Schmall, Anja;
    • Lang, Dagmar;
    • Goldmann, Torsten;
    • Eul, Bastian;
    • Dahlem, Gabriele;
    • Fink, Ludger;
    • Schermuly, Ralph-Theo;
    • Banat, Gamal-Andre;
    • Sibelius, Ulf;
    • Grimminger, Friedrich;
    • Vollmer, Ekkehard;
    • Seeger, Werner;
    • Grandel, Ulrich
    Publication type:
    Article