Works by Savai, Rajkumar

Results: 78
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    Interferon Regulatory Factor 9 Promotes Lung Cancer Progression via Regulation of Versican.

    Published in:
    Cancers, 2021, v. 13, n. 2, p. 208, doi. 10.3390/cancers13020208
    By:
    • Brunn, David;
    • Turkowski, Kati;
    • Günther, Stefan;
    • Weigert, Andreas;
    • Muley, Thomas;
    • Kriegsmann, Mark;
    • Winter, Hauke;
    • Dammann, Reinhard H.;
    • Stathopoulos, Georgios T.;
    • Thomas, Michael;
    • Guenther, Andreas;
    • Grimminger, Friedrich;
    • Pullamsetti, Soni S.;
    • Seeger, Werner;
    • Savai, Rajkumar
    Publication type:
    Article
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    KRAS and TP53 co-mutation predicts benefit of immune checkpoint blockade in lung adenocarcinoma.

    Published in:
    British Journal of Cancer, 2024, v. 131, n. 3, p. 524, doi. 10.1038/s41416-024-02746-z
    By:
    • Budczies, Jan;
    • Romanovsky, Eva;
    • Kirchner, Martina;
    • Neumann, Olaf;
    • Blasi, Miriam;
    • Schnorbach, Johannes;
    • Shah, Rajiv;
    • Bozorgmehr, Farastuk;
    • Savai, Rajkumar;
    • Stiewe, Thorsten;
    • Peters, Solange;
    • Schirmacher, Peter;
    • Thomas, Michael;
    • Kazdal, Daniel;
    • Christopoulos, Petros;
    • Stenzinger, Albrecht
    Publication type:
    Article
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    Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate.

    Published in:
    EMBO Molecular Medicine, 2016, v. 8, n. 12, p. 1380, doi. 10.15252/emmm.201606382
    By:
    • Mehta, Aditi;
    • Cordero, Julio;
    • Dobersch, Stephanie;
    • Romero‐Olmedo, Addi J;
    • Savai, Rajkumar;
    • Bodner, Johannes;
    • Chao, Cho‐Ming;
    • Fink, Ludger;
    • Guzmán‐Díaz, Ernesto;
    • Singh, Indrabahadur;
    • Dobreva, Gergana;
    • Rapp, Ulf R;
    • Günther, Stefan;
    • Ilinskaya, Olga N;
    • Bellusci, Saverio;
    • Dammann, Reinhard H;
    • Braun, Thomas;
    • Seeger, Werner;
    • Gattenlöhner, Stefan;
    • Tresch, Achim
    Publication type:
    Article
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    Premalignant Progression in the Lung: Knowledge Gaps and Novel Opportunities for Interception of Non–Small Cell Lung Cancer. An Official American Thoracic Society Research Statement.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2024, v. 210, n. 5, p. 548, doi. 10.1164/rccm.202406-1168ST
    By:
    • Moghaddam, Seyed Javad;
    • Savai, Rajkumar;
    • Salehi-Rad, Ramin;
    • Sengupta, Shreoshi;
    • Kammer, Michael N.;
    • Massion, Pierre;
    • Beane, Jennifer E.;
    • Ostrin, Edwin J.;
    • Priolo, Carmen;
    • Tennis, Meredith A.;
    • Stabile, Laura P.;
    • Bauer, Alison K.;
    • Sears, Catherine R.;
    • Szabo, Eva;
    • Rivera, M. Patricia;
    • Powell, Charles A.;
    • Kadara, Humam;
    • Jenkins, Brendan J.;
    • Dubinett, Steven M.;
    • Houghton, A. McGarry
    Publication type:
    Article
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    Reply to Zheng .

    Published in:
    2021
    By:
    • Eul, Bastian;
    • Cekay, Michael;
    • Tello, Khodr;
    • Wilhelm, Jochen;
    • Gattenlöhner, Stefan;
    • Sibelius, Ulf;
    • Grimminger, Friedrich;
    • Seeger, Werner;
    • Pullamsetti, Soni Savai;
    • Savai, Rajkumar
    Publication type:
    Letter to the Editor
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    Immune and Inflammatory Cell Involvement in the Pathology of Idiopathic Pulmonary Arterial Hypertension.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2012, v. 186, n. 9, p. 897, doi. 10.1164/rccm.201202-0335OC
    By:
    • Savai, Rajkumar;
    • Pullamsetti, Soni S.;
    • Kolbe, Julia;
    • Bieniek, Ewa;
    • Voswinckel, Robert;
    • Fink, Ludger;
    • Scheed, Axel;
    • Ritter, Christin;
    • Dahal, Bhola K.;
    • Vater, Axel;
    • Klussmann, Sven;
    • Ghofrani, Hossein A.;
    • Weissmann, Norbert;
    • Klepetko, Walter;
    • Banat, Gamal A.;
    • Seeger, Werner;
    • Grimminger, Friedrich;
    • Schermuly, Ralph T.
    Publication type:
    Article
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    Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis.

    Published in:
    Respiratory Research, 2010, v. 11, p. 146, doi. 10.1186/1465-9921-11-146
    By:
    • Nikolova, Sevdalina;
    • Guenther, Andreas;
    • Savai, Rajkumar;
    • Weissmann, Norbert;
    • Ghofrani, Hossein A.;
    • Konigshoff, Melanie;
    • Eickelberg, Oliver;
    • Klepetko, Walter;
    • Voswinckel, Robert;
    • Seeger, Werner;
    • Grimminger, Friedrich;
    • Schermuly, Ralph T.;
    • Pullamsetti, Soni S.
    Publication type:
    Article
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    Endotoxin induces proliferation of NSCLC in vitro and in vivo: role of COX-2 and EGFR activation.

    Published in:
    Cancer Immunology, Immunotherapy, 2013, v. 62, n. 2, p. 309, doi. 10.1007/s00262-012-1341-2
    By:
    • Hattar, Katja;
    • Savai, Rajkumar;
    • Subtil, Florentine;
    • Wilhelm, Jochen;
    • Schmall, Anja;
    • Lang, Dagmar;
    • Goldmann, Torsten;
    • Eul, Bastian;
    • Dahlem, Gabriele;
    • Fink, Ludger;
    • Schermuly, Ralph-Theo;
    • Banat, Gamal-Andre;
    • Sibelius, Ulf;
    • Grimminger, Friedrich;
    • Vollmer, Ekkehard;
    • Seeger, Werner;
    • Grandel, Ulrich
    Publication type:
    Article
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    RUNX1 interacts with lncRNA SMANTIS to regulate monocytic cell functions.

    Published in:
    Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06794-2
    By:
    • Weiss, Lisa M.;
    • Warwick, Timothy;
    • Zehr, Simonida;
    • Günther, Stefan;
    • Wolf, Sebastian;
    • Schmachtel, Tessa;
    • Izquierdo Ponce, Judit;
    • Pálfi, Katalin;
    • Teichmann, Tom;
    • Schneider, Alicia;
    • Stötzel, Julia;
    • Knapp, Stefan;
    • Weigert, Andreas;
    • Savai, Rajkumar;
    • Rieger, Michael A.;
    • Oellerich, Thomas;
    • Wittig, Ilka;
    • Oo, James A.;
    • Brandes, Ralf P.;
    • Leisegang, Matthias S.
    Publication type:
    Article
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    The Role of Dimethylarginine Dimethylaminohydrolase in Idiopathic Pulmonary Fibrosis.

    Published in:
    Science Translational Medicine, 2011, v. 3, n. 87, p. 1, doi. 10.1126/scitranslmed.3001725
    By:
    • Pullamsetti, Soni Savai;
    • Savai, Rajkumar;
    • Dumitrascu, Rio;
    • Dahal, Bhola Kumar;
    • Wilhelm, Jochen;
    • Konigshoff, Melanie;
    • Zakrzewicz, Dariusz;
    • Ghofrani, Hossein Ardeschir;
    • Weissmann, Norbert;
    • Eickelberg, Oliver;
    • Guenther, Andreas;
    • Leiper, James;
    • Seeger, Werner;
    • Grimminger, Friedrich;
    • Schermuly, Ralph Theo
    Publication type:
    Article
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    Inhibition of MicroRNA-17 Improves Lung and Heart Function in Experimental Pulmonary Hypertension.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2012, v. 185, n. 4, p. 409, doi. 10.1164/rccm.201106-1093OC
    By:
    • Pullamsetti, Soni S.;
    • Doebele, Carmen;
    • Fischer, Ariane;
    • Savai, Rajkumar;
    • Kojonazarov, Baktybek;
    • Daha, Bhola K.;
    • Ghofran, Hossein A.;
    • Weissmann, Norbert;
    • Grimminger, Friedrich;
    • Bonauer, Angelika;
    • Seeger, Werner;
    • Zeiher, Andreas M.;
    • Dimmeler, Stefanie;
    • Schermuly, Ralph T.
    Publication type:
    Article
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    Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-10066-7
    By:
    • Rubio, Karla;
    • Singh, Indrabahadur;
    • Dobersch, Stephanie;
    • Sarvari, Pouya;
    • Günther, Stefan;
    • Cordero, Julio;
    • Mehta, Aditi;
    • Wujak, Lukasz;
    • Cabrera-Fuentes, Hector;
    • Cho-Ming Chao;
    • Braubach, Peter;
    • Bellusci, Saverio;
    • Seeger, Werner;
    • Günther, Andreas;
    • Preissner, Klaus T.;
    • Wygrecka, Malgorzata;
    • Savai, Rajkumar;
    • Papy-Garcia, Dulce;
    • Dobreva, Gergana;
    • Heikenwalder, Mathias
    Publication type:
    Article
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    A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10044-z
    By:
    • Dabral, Swati;
    • Muecke, Christian;
    • Valasarajan, Chanil;
    • Schmoranzer, Mario;
    • Wietelmann, Astrid;
    • Semenza, Gregg L.;
    • Meister, Michael;
    • Muley, Thomas;
    • Seeger-Nukpezah, Tamina;
    • Samakovlis, Christos;
    • Weissmann, Norbert;
    • Grimminger, Friedrich;
    • Seeger, Werner;
    • Savai, Rajkumar;
    • Pullamsetti, Soni S.
    Publication type:
    Article
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    Epigenetic reactivation of transcriptional programs orchestrating fetal lung development in human pulmonary hypertension.

    Published in:
    Science Translational Medicine, 2022, v. 14, n. 648, p. 1, doi. 10.1126/scitranslmed.abe5407
    By:
    • Chelladurai, Prakash;
    • Kuenne, Carsten;
    • Bourgeois, Alice;
    • Günther, Stefan;
    • Valasarajan, Chanil;
    • Cherian, Anoop V.;
    • Rottier, Robbert J.;
    • Romanet, Charlotte;
    • Weigert, Andreas;
    • Boucherat, Olivier;
    • Eichstaedt, Christina A.;
    • Ruppert, Clemens;
    • Guenther, Andreas;
    • Braun, Thomas;
    • Looso, Mario;
    • Savai, Rajkumar;
    • Seeger, Werner;
    • Bauer, Uta-Maria;
    • Bonnet, Sébastien;
    • Pullamsetti, Soni Savai
    Publication type:
    Article
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    Tumor-derived exosomes in the regulation of macrophage polarization.

    Published in:
    Inflammation Research, 2020, v. 69, n. 5, p. 435, doi. 10.1007/s00011-020-01318-0
    By:
    • Baig, Mirza S.;
    • Roy, Anjali;
    • Rajpoot, Sajjan;
    • Liu, Dongfang;
    • Savai, Rajkumar;
    • Banerjee, Sreeparna;
    • Kawada, Manabu;
    • Faisal, Syed M.;
    • Saluja, Rohit;
    • Saqib, Uzma;
    • Ohishi, Tomokazu;
    • Wary, Kishore K.
    Publication type:
    Article
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    Lung cancer-associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell-immune cell cross-talk.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 416, p. 1, doi. 10.1126/scitranslmed.aai9048
    By:
    • Pullamsetti, Soni Savai;
    • Kojonazarov, Baktybek;
    • Storn, Samantha;
    • Gall, Henning;
    • Salazar, Ylia;
    • Wolf, Janine;
    • Weigert, Andreas;
    • El-Nikhely, Nefertiti;
    • Ghofrani, Hossein Ardeschir;
    • Krombach, Gabriele A.;
    • Fink, Ludger;
    • Gattenlöhner, Stefan;
    • Rapp, Ulf R.;
    • Schermuly, Ralph Theo;
    • Grimminger, Friedrich;
    • Seeger, Werner;
    • Savai, Rajkumar
    Publication type:
    Article
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    CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia.

    Published in:
    Inflammation & Regeneration, 2023, v. 43, n. 1, p. 1, doi. 10.1186/s41232-023-00301-6
    By:
    • Hirani, Dharmesh V.;
    • Thielen, Florian;
    • Mansouri, Siavash;
    • Danopoulos, Soula;
    • Vohlen, Christina;
    • Haznedar-Karakaya, Pinar;
    • Mohr, Jasmine;
    • Wilke, Rebecca;
    • Selle, Jaco;
    • Grosch, Thomas;
    • Mizik, Ivana;
    • Odenthal, Margarete;
    • Alvira, Cristina M.;
    • Kuiper-Makris, Celien;
    • Pryhuber, Gloria S.;
    • Pallasch, Christian;
    • van Koningsbruggen-Rietschel, S.;
    • Al-Alam, Denise;
    • Seeger, Werner;
    • Savai, Rajkumar
    Publication type:
    Article
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    Repurposing Thioridazine (TDZ) as an anti-inflammatory agent.

    Published in:
    Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-30763-5
    By:
    • Baig, Mirza S.;
    • Roy, Anjali;
    • Saqib, Uzma;
    • Rajpoot, Sajjan;
    • Srivastava, Mansi;
    • Naim, Adnan;
    • Liu, Dongfang;
    • Saluja, Rohit;
    • Faisal, Syed M.;
    • Pan, Qiuwei;
    • Turkowski, Kati;
    • Darwhekar, Gajanan N.;
    • Savai, Rajkumar
    Publication type:
    Article
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    The Multi-Modal Effect of the Anti-fibrotic Drug Pirfenidone on NSCLC.

    Published in:
    Frontiers in Oncology, 2020, v. 9, p. 1, doi. 10.3389/fonc.2019.01550
    By:
    • Marwitz, Sebastian;
    • Turkowski, Kati;
    • Nitschkowski, Dörte;
    • Weigert, Andreas;
    • Brandenburg, Julius;
    • Reiling, Norbert;
    • Thomas, Michael;
    • Reck, Martin;
    • Drömann, Daniel;
    • Seeger, Werner;
    • Rabe, Klaus F.;
    • Savai, Rajkumar;
    • Goldmann, Torsten
    Publication type:
    Article
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