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An integrated computational-experimental approach reveals Yersinia pestis genes essential across a narrow or a broad range of environmental conditions.
Published in:
BMC Microbiology, 2017, v. 17, p. 1, doi. 10.1186/s12866-017-1073-8
By:
- Senior, Nicola J.;
- Sasidharan, Kalesh;
- Saint, Richard J.;
- Scott, Andrew E.;
- Sarkar-Tyson, Mitali;
- Ireland, Philip M.;
- Bullifent, Helen L.;
- Yang, Z. Rong;
- Moore, Karen;
- Oyston, Petra C. F.;
- Atkins, Timothy P.;
- Atkins, Helen S.;
- Soyer, Orkun S.;
- Titball, Richard W.
Publication type:
Article
Phosphoethanolamine Transferases as Drug Discovery Targets for Therapeutic Treatment of Multi-Drug Resistant Pathogenic Gram-Negative Bacteria.
Published in:
Antibiotics (2079-6382), 2023, v. 12, n. 9, p. 1382, doi. 10.3390/antibiotics12091382
By:
- Thai, Van C.;
- Stubbs, Keith A.;
- Sarkar-Tyson, Mitali;
- Kahler, Charlene M.
Publication type:
Article
Anti-Virulence Therapeutic Approaches for Neisseria gonorrhoeae.
Published in:
Antibiotics (2079-6382), 2021, v. 10, n. 2, p. 103, doi. 10.3390/antibiotics10020103
By:
- Lim, Katherine Y. L.;
- Mullally, Christopher A.;
- Haese, Ethan C.;
- Kibble, Emily A.;
- McCluskey, Nicolie R.;
- Mikucki, Edward C.;
- Thai, Van C.;
- Stubbs, Keith A.;
- Sarkar-Tyson, Mitali;
- Kahler, Charlene M.;
- Brown, Angela
Publication type:
Article
A Noise Trimming and Positional Significance of Transposon Insertion System to Identify Essential Genes in Yersinia pestis.
Published in:
Scientific Reports, 2017, p. 41923, doi. 10.1038/srep41923
By:
- Yang, Zheng Rong;
- Bullifent, Helen L.;
- Moore, Karen;
- Paszkiewicz, Konrad;
- Saint, Richard J.;
- Southern, Stephanie J.;
- Champion, Olivia L.;
- Senior, Nicola J.;
- Sarkar-Tyson, Mitali;
- Oyston, Petra C. F.;
- Atkins, Timothy P.;
- Titball, Richard W.
Publication type:
Article
Characterization of secreted sphingosine-1-phosphate lyases required for virulence and intracellular survival of Burkholderia pseudomallei.
Published in:
Molecular Microbiology, 2016, v. 102, n. 6, p. 1004, doi. 10.1111/mmi.13531
By:
- Custódio, Rafael;
- McLean, Christopher J.;
- Scott, Andrew E.;
- Lowther, Jonathan;
- Kennedy, Amanda;
- Clarke, David J.;
- Campopiano, Dominic J.;
- Sarkar‐Tyson, Mitali;
- Brown, Alan R.
Publication type:
Article
Identification of active main metabolites of anti‐infective inhibitors of the macrophage infectivity potentiator protein by liquid chromatography using mass detection.
Published in:
Archiv der Pharmazie, 2024, v. 357, n. 8, p. 1, doi. 10.1002/ardp.202400032
By:
- Lohr, Theresa;
- Scheuplein, Nicolas Julian;
- Jenkins, Christopher;
- Norville, Isobel;
- Erk, Christine;
- Stapf, Maximilian;
- Kirchner, Lukas;
- Sarkar‐Tyson, Mitali;
- Holzgrabe, Ulrike
Publication type:
Article
Inhibition of macrophage infectivity potentiator in Burkholderia pseudomallei suppresses pro-inflammatory responses in murine macrophages.
Published in:
Frontiers in Cellular & Infection Microbiology, 2024, p. 1, doi. 10.3389/fcimb.2024.1353682
By:
- Iwasaki, Jua;
- Bzdyl, Nicole M.;
- Lin-Sullivan, Dion J. M.;
- Scheuplein, Nicolas J.;
- Dueñas, Maria Emilia;
- de Jong, Emma;
- Harmer, Nicholas J.;
- Holzgrabe, Ulrike;
- Sarkar-Tyson, Mitali
Publication type:
Article
A Genomic Survey of Positive Selection in Burkholderia pseudomallei Provides Insights into the Evolution of Accidental Virulence.
Published in:
PLoS Pathogens, 2010, v. 6, n. 4, p. 1, doi. 10.1371/journal.ppat.1000845
By:
- Nandi, Tannistha;
- Ong, Catherine;
- Pratap Singh, Arvind;
- Boddey, Justin;
- Atkins, Timothy;
- Sarkar-Tyson, Mitali;
- Essex-Lopresti, Angela E.;
- Hui Hoon Chua;
- Pearson, Talima;
- Kreisberg, Jason F.;
- Nilsson, Christina;
- Ariyaratne, Pramila;
- Ronning, Catherine;
- Losada, Liliana;
- Yijun Ruan;
- Wing-Kin Sung;
- Woods, Donald;
- Titball, Richard W.;
- Beacham, Ifor;
- Peak, Ian
Publication type:
Article
Novel small molecules that increase the susceptibility of Neisseria gonorrhoeae to cationic antimicrobial peptides by inhibiting lipid A phosphoethanolamine transferase.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2022, v. 77, n. 9, p. 2441, doi. 10.1093/jac/dkac204
By:
- Mullally, Christopher;
- Stubbs, Keith A;
- Thai, Van C;
- Anandan, Anandhi;
- Bartley, Stephanie;
- Scanlon, Martin J;
- Jarvis, Gary A;
- John, Constance M;
- Lim, Katherine Y L;
- Sullivan, Courtney M;
- Sarkar-Tyson, Mitali;
- Vrielink, Alice;
- Kahler, Charlene M
Publication type:
Article
N‐acetyl‐β‐hexosaminidase activity is important for chitooligosaccharide metabolism and biofilm formation in Burkholderia pseudomallei.
Published in:
Environmental Microbiology, 2024, v. 26, n. 1, p. 1, doi. 10.1111/1462-2920.16571
By:
- Moran, Clare L.;
- Debowski, Aleksandra;
- Vrielink, Alice;
- Stubbs, Keith;
- Sarkar‐Tyson, Mitali
Publication type:
Article
Macrophage infectivity potentiator protein, a peptidyl prolyl cis-trans isomerase, essential for Coxiella burnetii growth and pathogenesis.
Published in:
PLoS Pathogens, 2023, v. 19, n. 7, p. 1, doi. 10.1371/journal.ppat.1011491
By:
- Debowski, Aleksandra W.;
- Bzdyl, Nicole M.;
- Thomas, David R.;
- Scott, Nichollas E.;
- Jenkins, Christopher H.;
- Iwasaki, Jua;
- Kibble, Emily A.;
- Khoo, Chen Ai;
- Scheuplein, Nicolas J.;
- Seibel, Pamela M.;
- Lohr, Theresa;
- Metters, Georgie;
- Bond, Charles S.;
- Norville, Isobel H.;
- Stubbs, Keith A.;
- Harmer, Nicholas J.;
- Holzgrabe, Ulrike;
- Newton, Hayley J.;
- Sarkar-Tyson, Mitali
Publication type:
Article

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