Works by Saravanan, Konda Mani

Results: 46

MicroRNA-mediated regulation of BCL-2 in breast cancer.

Published in:

AIMS Molecular Science, 2025, v. 12, n. 1, p. 1, doi. 10.3934/molsci.2025003

By:

Mayuri, Kannan;
Vickram, Sundaram;
Anand, Thirunavukarasou;
Saravanan, Konda Mani

Publication type:

Article

Importance of Inter-residue Contacts for Understanding Protein Folding and Unfolding Rates, Remote Homology, and Drug Design.

Published in:

Molecular Biotechnology, 2025, v. 67, n. 3, p. 862, doi. 10.1007/s12033-024-01119-4

By:

Harihar, Balasubramanian;
Saravanan, Konda Mani;
Gromiha, Michael M.;
Selvaraj, Samuel

Publication type:

Article

Waking Up the Sleep Field: An Overview on the Implications of Genetics and Bioinformatics of Sleep.

Published in:

Molecular Biotechnology, 2024, v. 66, n. 5, p. 919, doi. 10.1007/s12033-023-01009-1

By:

Pandi-Perumal, Seithikurippu R.;
Saravanan, Konda Mani;
Paul, Sayan;
Namasivayam, Ganesh Pandian;
Chidambaram, Saravana Babu

Publication type:

Article

CRISPR/Cas-Based Modifications for Therapeutic Applications: A Review.

Published in:

Molecular Biotechnology, 2022, v. 64, n. 4, p. 355, doi. 10.1007/s12033-021-00422-8

By:

Bharathkumar, Nagaraj;
Sunil, Abraham;
Meera, Prabhakar;
Aksah, Sam;
Kannan, Muthu;
Saravanan, Konda Mani;
Anand, Thirunavukarasou

Publication type:

Article

Methanodibenzo[ b , f ][1,5]dioxocins as Novel Glutaminase Inhibitor with Anti-Glioblastoma Potential.

Published in:

Cancers, 2023, v. 15, n. 4, p. 1010, doi. 10.3390/cancers15041010

By:

Murugesan, Akshaya;
Kari, Sana;
Shrestha, Anita;
Assoah, Benedicta;
Saravanan, Konda Mani;
Murugesan, Monica;
Thiyagarajan, Ramesh;
Candeias, Nuno R.;
Kandhavelu, Meenakshisundaram

Publication type:

Article

Targeting Orphan G Protein-Coupled Receptor 17 with T0 Ligand Impairs Glioblastoma Growth.

Published in:

Cancers, 2021, v. 13, n. 15, p. 3773, doi. 10.3390/cancers13153773

By:

Doan, Phuong;
Nguyen, Phung;
Murugesan, Akshaya;
Subramanian, Kumar;
Konda Mani, Saravanan;
Kalimuthu, Vignesh;
Abraham, Bobin George;
Stringer, Brett W.;
Balamuthu, Kadalmani;
Yli-Harja, Olli;
Kandhavelu, Meenakshisundaram

Publication type:

Article

DeepBindGCN: Integrating Molecular Vector Representation with Graph Convolutional Neural Networks for Protein–Ligand Interaction Prediction.

Published in:

Molecules, 2023, v. 28, n. 12, p. 4691, doi. 10.3390/molecules28124691

By:

Zhang, Haiping;
Saravanan, Konda Mani;
Zhang, John Z. H.

Publication type:

Article

Evaluation of anti-cancer effect of zerumbone and cisplatin on N-nitrosodiethylamine induced hepatic cancer in freshwater fish (Danio rerio).

Published in:

Natural Product Research, 2022, v. 36, n. 18, p. 4794, doi. 10.1080/14786419.2021.2012672

By:

Srimathi Devi, Jegannathan;
Haripriya, Dayalan;
Arul, Santhosh;
Saravanan, Konda Mani;
Bupesh, Giridharan

Publication type:

Article

Hexadecanoic acid analogs as potential CviR-mediated quorum sensing inhibitors in Chromobacterium violaceum: an in silico study.

Published in:

Journal of Biomolecular Structure & Dynamics, 2025, v. 43, n. 7, p. 3635, doi. 10.1080/07391102.2023.2299945

By:

Senthil, Renganathan;
Archunan, Govindaraju;
Vithya, Dharmaraj;
Saravanan, Konda Mani

Publication type:

Article

Molecular modeling and dynamics studies of the synthetic small molecule agonists with GPR17 and P2Y1 receptor.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 23, p. 12908, doi. 10.1080/07391102.2021.1977707

By:

Murugesan, Akshaya;
Nguyen, Phung;
Ramesh, Thiyagarajan;
Yli-Harja, Olli;
Kandhavelu, Meenakshisundaram;
Saravanan, Konda Mani

Publication type:

Article

Transcriptomic analysis of glioblastoma multiforme providing new insights into GPR17 signaling communication.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 6, p. 2586, doi. 10.1080/07391102.2020.1841029

By:

Mutharasu, Gnanavel;
Murugesan, Akshaya;
Konda Mani, Saravanan;
Yli-Harja, Olli;
Kandhavelu, Meenakshisundaram

Publication type:

Article

Structural basis for the inhibition of SARS-CoV2 main protease by Indian medicinal plant-derived antiviral compounds.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 5, p. 1970, doi. 10.1080/07391102.2020.1834457

By:

Saravanan, Konda Mani;
Zhang, Haiping;
Senthil, Renganathan;
Vijayakumar, Kevin Kumar;
Sounderrajan, Vignesh;
Wei, Yanjie;
Shakila, Harshavardhan

Publication type:

Article

Systematic analysis of NO Regular Secondary structural regions (NORS) in membrane and non-membrane proteins.

Published in:

2020

By:

Saravanan, Konda Mani;
Peng, Yin;
Wei, Yanjie

Publication type:

Letter

Sequence fingerprints distinguish erroneous from correct predictions of intrinsically disordered protein regions.

Published in:

Journal of Biomolecular Structure & Dynamics, 2018, v. 36, n. 16, p. 4338, doi. 10.1080/07391102.2017.1415822

By:

Saravanan, Konda Mani;
Dunker, A. Keith;
Krishnaswamy, Sankaran

Publication type:

Article

Computational profiling of pore properties of outer membrane proteins.

Published in:

Journal of Biomolecular Structure & Dynamics, 2017, v. 35, n. 11, p. 2372, doi. 10.1080/07391102.2016.1220329

By:

Manoharan, Prabu;
Saravanan, Konda Mani

Publication type:

Article

Preliminary phytochemical screening, Antibacterial potential and GCMS analysis of two medicinal plant extracts.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2016, v. 29, n. 3, p. 819

By:

Vijayaram, Seerangaraj;
Kannan, Suruli;
Saravanan, Konda Mani;
Vasantharaj, Seerangaraj;
Sathiyavimal, Selvam;
Palanisamy, Senthilkumar P.

Publication type:

Article

Identifying Potent Fat Mass and Obesity-Associated Protein Inhibitors Using Deep Learning-Based Hybrid Procedures.

Published in:

BioMedInformatics, 2024, v. 4, n. 1, p. 347, doi. 10.3390/biomedinformatics4010020

By:

Mayuri, Kannan;
Varalakshmi, Durairaj;
Tharaheswari, Mayakrishnan;
Somala, Chaitanya Sree;
Priya, Selvaraj Sathya;
Bharathkumar, Nagaraj;
Senthil, Renganathan;
Kushwah, Raja Babu Singh;
Vickram, Sundaram;
Anand, Thirunavukarasou;
Saravanan, Konda Mani

Publication type:

Article

Neurogranin in Alzheimer's Disease: Roles in synaptic function, pathology, and potential as a diagnostic biomarker.

Published in:

AIMS Molecular Science, 2024, v. 11, n. 4, p. 1, doi. 10.3934/molsci.2024020

By:

Bavaharini, Rajkumar;
Somala, Chaitanya Sree;
Saravanan, Konda Mani;
Anand, Thirunavukarasou

Publication type:

Article

Instrumentals behind embryo and cancer: a platform for prospective future in cancer research.

Published in:

AIMS Molecular Science, 2022, v. 9, n. 1, p. 25, doi. 10.3934/molsci.2022002

By:

Sundaram, Kishore Kumar Meenakshi;
Bupesh, Giridharan;
Saravanan, Konda Mani

Publication type:

Article

Synthesis and preclinical validation of novel P2Y1 receptor ligands as a potent anti-prostate cancer agent.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-55194-8

By:

Le, Hien Thi Thu;
Rimpilainen, Tatu;
Konda Mani, Saravanan;
Murugesan, Akshaya;
Yli-Harja, Olli;
Candeias, Nuno R.;
Kandhavelu, Meenakshisundaram

Publication type:

Article

An Integrated Deep Learning and Molecular Dynamics Simulation-Based Screening Pipeline Identifies Inhibitors of a New Cancer Drug Target TIPE2.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.772296

By:

Zhang, Haiping;
Li, Junxin;
Saravanan, Konda Mani;
Wu, Hao;
Wang, Zhichao;
Wu, Du;
Wei, Yanjie;
Lu, Zhen;
Chen, Youhai H.;
Wan, Xiaochun;
Pan, Yi

Publication type:

Article

Sequence and structural analysis of fibronectin‐binding protein reveals importance of multiple intrinsic disordered tandem repeats.

Published in:

Journal of Molecular Recognition, 2019, v. 32, n. 4, p. N.PAG, doi. 10.1002/jmr.2768

By:

Saravanan, Konda Mani;
Ponnuraj, Karthe

Publication type:

Article

A novel machine learning based approach for iPS progenitor cell identification.

Published in:

PLoS Computational Biology, 2019, v. 15, n. 12, p. N.PAG, doi. 10.1371/journal.pcbi.1007351

By:

Zhang, Haishan;
Shao, Ximing;
Peng, Yin;
Teng, Yanning;
Saravanan, Konda Mani;
Zhang, Huiling;
Li, Hongchang;
Wei, Yanjie

Publication type:

Article

Cross‐Kingdom Genomic Conservation of Putative Human Sleep‐Related Genes: Phylogenomic Evidence From Chlamydomonas reinhardtii.

Published in:

Journal of Cellular Biochemistry, 2025, v. 126, n. 4, p. 1, doi. 10.1002/jcb.70030

By:

Pandi‐Perumal, Seithikurippu R.;
Saravanan, Konda Mani;
Paul, Sayan;
Abraham, George C.;
Warren Spence, David;
Chidambaram, Saravana Babu

Publication type:

Article

Structural analysis of human G‐protein‐coupled receptor 17 ligand binding sites.

Published in:

Journal of Cellular Biochemistry, 2023, v. 124, n. 4, p. 533, doi. 10.1002/jcb.30388

By:

Konda Mani, Saravanan;
Thiyagarajan, Ramesh;
Yli‐Harja, Olli;
Kandhavelu, Meenakshisundaram;
Murugesan, Akshaya

Publication type:

Article

PreFRP: Prediction and visualization of fluctuation residues in proteins.

Published in:

Journal of Natural Science, Biology & Medicine, 2016, v. 7, n. 2, p. 124, doi. 10.4103/0976-9668.184696

By:

Saravanan, Konda Mani;
Senthil, Renganathan

Publication type:

Article

Better theoretical models and protein design experiments can help to understand protein folding.

Published in:

Journal of Natural Science, Biology & Medicine, 2015, v. 6, n. 1, p. 202, doi. 10.4103/0976-9668.149122

By:

Saravanan, Konda Mani;
Selvaraj, Samuel

Publication type:

Article

Unraveling the Mysteries of Sleep: Exploring Phylogenomic Sleep Signals in the Recently Characterized Archaeal Phylum Lokiarchaeota near Loki's Castle.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 1, p. 60, doi. 10.3390/ijms26010060

By:

Pandi-Perumal, Seithikurippu R.;
Saravanan, Konda Mani;
Paul, Sayan;
Spence, David Warren;
Chidambaram, Saravana Babu

Publication type:

Article

Benzenesulfonamide Analogs: Synthesis, Anti-GBM Activity and Pharmacoprofiling.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 15, p. 12276, doi. 10.3390/ijms241512276

By:

Murugesan, Akshaya;
Konda Mani, Saravanan;
Thiyagarajan, Ramesh;
Palanivel, Suresh;
Gurbanov, Atash V.;
Zubkov, Fedor I.;
Kandhavelu, Meenakshisundaram

Publication type:

Article

Identifying the miRNA Signature Association with Aging-Related Senescence in Glioblastoma.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 2, p. 517, doi. 10.3390/ijms22020517

By:

Gnanavel, Mutharasu;
Murugesan, Akshaya;
Konda Mani, Saravanan;
Yli-Harja, Olli;
Kandhavelu, Meenakshisundaram

Publication type:

Article

Evaluation of residue-residue contact prediction methods: From retrospective to prospective.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 5, p. 1, doi. 10.1371/journal.pcbi.1009027

By:

Zhang, Huiling;
Bei, Zhendong;
Xi, Wenhui;
Hao, Min;
Ju, Zhen;
Saravanan, Konda Mani;
Zhang, Haiping;
Guo, Ning;
Wei, Yanjie

Publication type:

Article

A novel virtual screening procedure identifies Pralatrexate as inhibitor of SARS-CoV-2 RdRp and it reduces viral replication in vitro.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008489

By:

Zhang, Haiping;
Yang, Yang;
Li, Junxin;
Wang, Min;
Saravanan, Konda Mani;
Wei, Jinli;
Tze-Yang Ng, Justin;
Tofazzal Hossain, Md.;
Liu, Maoxuan;
Zhang, Huiling;
Ren, Xiaohu;
Pan, Yi;
Peng, Yin;
Shi, Yi;
Wan, Xiaochun;
Liu, Yingxia;
Wei, Yanjie

Publication type:

Article

Importance of Fluctuating Amino Acid Residues in Folding and Binding of Proteins.

Published in:

Avicenna Journal of Medical Biotechnology, 2019, v. 11, n. 4, p. 339

By:

Senthil, Renganathan;
Usha, Singaravelu;
Saravanan, Konda Mani

Publication type:

Article

Deep Learning Based Drug Screening for Novel Coronavirus 2019-nCov.

Published in:

Interdisciplinary Sciences: Computational Life Sciences, 2020, v. 12, n. 3, p. 368, doi. 10.1007/s12539-020-00376-6

By:

Zhang, Haiping;
Saravanan, Konda Mani;
Yang, Yang;
Hossain, Md. Tofazzal;
Li, Junxin;
Ren, Xiaohu;
Pan, Yi;
Wei, Yanjie

Publication type:

Article

Enhancing oral cancer research with natural language processing: From insights to innovations.

Published in:

2024

By:

Saravanan, Konda Mani

Publication type:

Letter

DeepBindPoc: a deep learning method to rank ligand binding pockets using molecular vector representation.

Published in:

PeerJ, 2020, p. 1, doi. 10.7717/peerj.8864

By:

Haiping Zhang;
Saravanan, Konda Mani;
Jinzhi Lin;
Linbu Liao;
Ng, Justin Tze-Yang;
Jiaxiu Zhou;
Yanjie Wei

Publication type:

Article

DeepBindRG: a deep learning based method for estimating effective protein–ligand affinity.

Published in:

PeerJ, 2019, p. 1, doi. 10.7717/peerj.7362

By:

Haiping Zhang;
Linbu Liao;
Saravanan, Konda Mani;
Peng Yin;
Yanjie Wei

Publication type:

Article

Erratum: Viswanathan, A., et al. Battling Glioblastoma: A Novel Tyrosine Kinase Inhibitor with Multi-Dimensional Anti-Tumor Effect (Running Title: Cancer Cells Death Signalling Activation). Cells 2019, 8 , 1624.

Published in:

2020

By:

Viswanathan, Anisha;
Musa, Aliyu;
Murugesan, Akshaya;
Vale, João R.;
Afonso, Carlos A. M.;
Mani, Saravanan Konda;
Yli-Harja, Olli;
Candeias, Nuno R.;
Kandhavelu, Meenakshisundaram

Publication type:

Correction Notice

Battling Glioblastoma: A Novel Tyrosine Kinase Inhibitor with Multi-Dimensional Anti-Tumor Effect (Running Title: Cancer Cells Death Signalling Activation).

Published in:

Cells (2073-4409), 2019, v. 8, n. 12, p. 1624, doi. 10.3390/cells8121624

By:

Viswanathan, Anisha;
Musa, Aliyu;
Murugesan, Akshaya;
Vale, João R.;
Afonso, Carlos A. M.;
Konda Mani, Saravanan;
Yli-Harja, Olli;
Candeias, Nuno R.;
Kandhavelu, Meenakshisundaram

Publication type:

Article

A Review on the Potential Species of the Zingiberaceae Family with Anti-viral Efficacy Towards Enveloped Viruses.

Published in:

Journal of Pure & Applied Microbiology, 2022, v. 16, n. 2, p. 796, doi. 10.22207/JPAM.16.2.35

By:

Balaji, A. P. B.;
Bhuvaneswari, Srinivasan;
Raj, Leon Stephan;
Bupesh, Giridharan;
Meenakshisundaram, Kishore Kumar;
Saravanan, Konda Mani

Publication type:

Article

Characterization of Novel Antimicrobial Peptides from the Epidermis of Clarias batrachus Catfish.

Published in:

International Journal of Peptide Research & Therapeutics, 2024, v. 30, n. 2, p. 1, doi. 10.1007/s10989-024-10589-8

By:

Giridharan, Bupesh;
Chinnaiah, Amutha;
Saravanan, Konda Mani;
Parthasarathy, Sudharsan;
Meenakshi Sundaram, Kishore Kumar;
Tharumasivam, Siva Vijayakumar;
Pankaj, Pranay Punj;
Govindaraju, Archunan;
Haripriya, Dayalan;
Sahoo, Uttam Kumar

Publication type:

Article

Therapeutic Potential of FTO Demethylase in Metabolism and Disease Pathways.

Published in:

2025

By:

Somala, Chaitanya Sree;
Sathyapriya, Selvaraj;
Bharathkumar, Nagaraj;
Anand, Thirunavukarasou;
Mathangi, Damal Chandrasekar;
Saravanan, Konda Mani

Publication type:

Literature Review

Revolutionizing GPCR–ligand predictions: DeepGPCR with experimental validation for high-precision drug discovery.

Published in:

Briefings in Bioinformatics, 2024, v. 25, n. 4, p. 1, doi. 10.1093/bib/bbae281

By:

Zhang, Haiping;
Fan, Hongjie;
Wang, Jixia;
Hou, Tao;
Saravanan, Konda Mani;
Xia, Wei;
Kan, Hei Wun;
Li, Junxin;
Zhang, John Z H;
Liang, Xinmiao;
Chen, Yang

Publication type:

Article

Generating and screening de novo compounds against given targets using ultrafast deep learning models as core components.

Published in:

Briefings in Bioinformatics, 2022, v. 23, n. 4, p. 1, doi. 10.1093/bib/bbac226

By:

Zhang, Haiping;
Saravanan, Konda Mani;
Yang, Yang;
Wei, Yanjie;
Yi, Pan;
Zhang, John Z H

Publication type:

Article

RETRACTED ARTICLE: Expression and preliminary characterization of the potential vaccine candidate LipL32 of leptospirosis.

Published in:

2023

By:

Govindan, Pothiaraj;
Manjusha, Packiyadass;
Saravanan, Konda Mani;
Natesan, Vijayakumar;
Salmen, Saleh H.;
Alfarraj, Saleh;
Wainwright, Milton;
Shakila, Harshavardhan

Publication type:

Correction Notice

A novel EGFR inhibitor, HNPMI, regulates apoptosis and oncogenesis by modulating BCL‐2/BAX and p53 in colon cancer.

Published in:

British Journal of Pharmacology, 2024, v. 181, n. 1, p. 107, doi. 10.1111/bph.16141

By:

Kandhavelu, Jeyalakshmi;
Subramanian, Kumar;
Naidoo, Vivash;
Sebastianelli, Giulia;
Doan, Phuong;
Konda Mani, Saravanan;
Yapislar, Hande;
Haciosmanoglu, Ebru;
Arslan, Leman;
Ozer, Samed;
Thiyagarajan, Ramesh;
Candeias, Nuno R.;
Penny, Clement;
Kandhavelu, Meenakshisundaram;
Murugesan, Akshaya

Publication type:

Article