Works matching AU Sansom, Mark S P

Results: 80

Structure of a KirBac potassium channel with an open bundle crossing indicates a mechanism of channel gating.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 2, p. 158, doi. 10.1038/nsmb.2208

By:

Bavro, Vassiliy N;
De Zorzi, Rita;
Schmidt, Matthias R;
Muniz, João R C;
Zubcevic, Lejla;
Sansom, Mark S P;
Vénien-Bryan, Catherine;
Tucker, Stephen J

Publication type:

Article

An aqueous H+ permeation pathway in the voltage-gated proton channel Hv1.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 7, p. 869, doi. 10.1038/nsmb.1826

By:

Ramsey, I. Scott;
Mokrab, Younes;
Carvacho, Ingrid;
Sands, Zara A.;
Sansom, Mark S. P.;
Clapham, David E.

Publication type:

Article

Epock: rapid analysis of protein pocket dynamics.

Published in:

2015

By:

Laurent, Benoist;
Chavent, Matthieu;
Cragnolini, Tristan;
Dahl, Anna Caroline E.;
Pasquali, Samuela;
Derreumaux, Philippe;
Sansom, Mark S. P.;
Baaden, Marc

Publication type:

Product Review

Bendix: intuitive helix geometry analysis and abstraction.

Published in:

Bioinformatics, 2012, v. 28, n. 16, p. 2193, doi. 10.1093/bioinformatics/bts357

By:

Dahl, Anna Caroline E.;
Chavent, Matthieu;
Sansom, Mark S. P.

Publication type:

Article

Analyzing protein topology based on Laguerre tessellation of a pore-traversing water network.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31422-5

By:

Esque, Jérémy;
Sansom, Mark S. P.;
Baaden, Marc;
Oguey, Christophe

Publication type:

Article

Membrane-binding mechanism of the EEA1 FYVE domain revealed by multi-scale molecular dynamics simulations.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.pcbi.1008807

By:

Larsen, Andreas Haahr;
Tata, Lilya;
John, Laura H.;
Sansom, Mark S. P.

Publication type:

Article

The Integrin Receptor in Biologically Relevant Bilayers: Insights from Molecular Dynamics Simulations.

Published in:

2017

By:

Kalli, Antreas;
Rog, Tomasz;
Vattulainen, Ilpo;
Campbell, Iain;
Sansom, Mark;
Kalli, Antreas C;
Campbell, Iain D;
Sansom, Mark S P

Publication type:

journal article

Lipidbook: a public repository for force-field parameters used in membrane simulations.

Published in:

2010

By:

Domański, Jan;
Stansfeld, Phillip J.;
Sansom, Mark S. P.;
Beckstein, Oliver;
Domański, Jan

Publication type:

journal article

Conformational dynamics of helix S6 from Shaker potassium channel: Simulation studies.

Published in:

Biopolymers, 2002, v. 64, n. 6, p. 303, doi. 10.1002/bip.10197

By:

Bright, Joanne N.;
Shrivastava, Indira H.;
Cordes, Frank S.;
Sansom, Mark S. P.

Publication type:

Article

Transmembrane domains of viral ion channel proteins: A molecular dynamics simulation study.

Published in:

Biopolymers, 2000, v. 53, n. 7, p. 529, doi. 10.1002/(SICI)1097-0282(200006)53:7<529::AID-BIP1>3.0.CO;2-6

By:

Fischer, Wolfgang B.;
Forrest, Lucy R.;
Smith, Graham R.;
Sansom, Mark S. P.

Publication type:

Article

Molecular dynamics simulations of isolated transmembrane helices of potassium channels.

Published in:

Biopolymers, 1996, v. 39, n. 4, p. 503, doi. 10.1002/(SICI)1097-0282(199610)39:4<503::AID-BIP3>3.0.CO;2-0

By:

Kerr, Ian D.;
Son, Hyeon S.;
Sankararamakrishnan, R.;
Sansom, Mark S. P.

Publication type:

Article

Supramolecular assemblies underpin turnover of outer membrane proteins in bacteria.

Published in:

Nature, 2015, v. 523, n. 7560, p. 333, doi. 10.1038/nature14461

By:

Rassam, Patrice;
Copeland, Nikki A.;
Birkholz, Oliver;
Tóth, Csaba;
Chavent, Matthieu;
Duncan, Anna L.;
Cross, Stephen J.;
Housden, Nicholas G.;
Kaminska, Renata;
Seger, Urban;
Quinn, Diana M.;
Garrod, Tamsin J.;
Sansom, Mark S. P.;
Piehler, Jacob;
Baumann, Christoph G.;
Kleanthous, Colin

Publication type:

Article

On the interpretation of reflectivity data from lipid bilayers in terms of molecular-dynamics models.

Published in:

Acta Crystallographica: Section D, Structural Biology, 2016, v. 72, n. 12, p. 1227, doi. 10.1107/S2059798316016235

By:

Hughes, Arwel V.;
Ciesielski, Fillip;
Kalli, Antreas C.;
Clifton, Luke A.;
Charlton, Timothy R.;
Sansom, Mark S. P.;
Webster, John R. P.

Publication type:

Article

Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscs.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32594-5

By:

Kumar, Arvind;
Kindig, Kayla;
Rao, Shanlin;
Zaki, Afroditi-Maria;
Basak, Sandip;
Sansom, Mark S. P.;
Biggin, Philip C.;
Chakrapani, Sudha

Publication type:

Article

Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28511-5

By:

Jojoa-Cruz, Sebastian;
Saotome, Kei;
Tsui, Che Chun Alex;
Lee, Wen-Hsin;
Sansom, Mark S. P.;
Murthy, Swetha E.;
Patapoutian, Ardem;
Ward, Andrew B.

Publication type:

Article

An atomic detail model for the human ATP binding cassette transporter P-glycoprotein derived from disulfide cross-linking and homology modeling.

Published in:

FASEB Journal, 2003, v. 17, n. 15, p. 2287, doi. 10.1096/fj.03-0107fje

By:

Stenham, Daniella R.;
Campbell, Jeff D.;
Sansom, Mark S. P.;
Higgins, Christopher F.;
Kerr, Ian D.;
Linton, Kenneth J.

Publication type:

Article

Identification of a Functionally Important NegativelyCharged Residue Within the Second Catalytic Site of theSUR1 Nucleotide-Binding Domains.

Published in:

Diabetes, 2004, v. 53, p. S123, doi. 10.2337/diabetes.53.suppl_3.S123

By:

Campbell, Jeff D.;
Proks, Peter;
Lippiat, Jonathan D.;
Sansom, Mark S. P.;
Ashcroft, Frances M.

Publication type:

Article

The effects of stretch activation on ionic selectivity of the TREK-2 K2P K channel.

Published in:

Channels (19336950), 2017, v. 11, n. 5, p. 482, doi. 10.1080/19336950.2017.1356955

By:

Nematian-Ardestani, Ehsan;
Jarerattanachat, Viwan;
Aryal, Prafulla;
Sansom, Mark S. P.;
Tucker, Stephen J.

Publication type:

Article

A BEST example of channel structure annotation by molecular simulation.

Published in:

Channels (19336950), 2017, v. 11, n. 4, p. 347, doi. 10.1080/19336950.2017.1306163

By:

Rao, Shanlin;
Klesse, Gianni;
Stansfeld, Phillip J.;
Tucker, Stephen J.;
Sansom, Mark S. P.

Publication type:

Article

Anomalous Dynamics of a Lipid Recognition Protein on a Membrane Surface.

Published in:

Scientific Reports, 2015, p. 18245, doi. 10.1038/srep18245

By:

Yamamoto, Eiji;
Kalli, Antreas C.;
Akimoto, Takuma;
Yasuoka, Kenji;
Sansom, Mark S. P.

Publication type:

Article

The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids.

Published in:

Scientific Reports, 2015, p. 9198, doi. 10.1038/srep09198

By:

Hedger, George;
Sansom, Mark S. P.;
Koldsø, Heidi

Publication type:

Article

Functional characterization of a mutated chicken α7 nicotinic acetylcholine receptor subunit with a leucine residue inserted in transmembrane domain 2.

Published in:

British Journal of Pharmacology, 1998, v. 124, n. 4, p. 747, doi. 10.1038/sj.bjp.0701866

By:

Buckingham, Steven D;
Adcock, Charlotte;
Sansom, Mark S P;
Sattelle, David B;
Baylis, Howard A

Publication type:

Article

How nanoscale protein interactions determine the mesoscale dynamic organisation of bacterial outer membrane proteins.

Published in:

Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-05255-9

By:

Chavent, Matthieu;
Duncan, Anna L.;
Rassam, Patrice;
Birkholz, Oliver;
Hélie, Jean;
Reddy, Tyler;
Beliaev, Dmitry;
Hambly, Ben;
Piehler, Jacob;
Kleanthous, Colin;
Sansom, Mark S. P.

Publication type:

Article

Membrane Perturbation by Carbon Nanotube Insertion: Pathways to Internalization.

Published in:

Small, 2013, v. 9, n. 21, p. 3639, doi. 10.1002/smll.201202640

By:

Lelimousin, Mickaël;
Sansom, Mark S. P.

Publication type:

Article

Modeling and simulations of a bacterial outer membrane protein: OprF from Pseudomonas aeruginosa.

Published in:

Proteins, 2006, v. 63, n. 1, p. 6, doi. 10.1002/prot.20845

By:

Khalid, Syma;
Bond, Peter J.;
Deol, Sundeep S.;
Sansom, Mark S. P.

Publication type:

Article

Comparative molecular dynamics-Similar folds and similar motions?

Published in:

Proteins, 2005, v. 61, n. 4, p. 809, doi. 10.1002/prot.20672

By:

Pang, Andrew;
Arinaminpathy, Yalini;
Sansom, Mark S. P.;
Biggin, Philip C.

Publication type:

Article

A mutation (R826W) in nucleotide-binding domain 1 of ABCC8 reduces ATPase activity and causes transient neonatal diabetes.

Published in:

EMBO Reports, 2008, v. 9, n. 7, p. 648, doi. 10.1038/embor.2008.71

By:

de Wet, Heidi;
Proks, Peter;
Lafond, Mathilde;
Aittoniemi, Jussi;
Sansom, Mark S P;
Flanagan, Sarah E;
Pearson, Ewan R;
Hattersley, Andrew T;
Ashcroft, Frances M

Publication type:

Article

Structural and functional analysis of the putative pH sensor in the Kir1.1 (ROMK) potassium channel.

Published in:

EMBO Reports, 2006, v. 7, n. 6, p. 611, doi. 10.1038/sj.embor.7400678

By:

Rapedius, Markus;
Haider, Shozeb;
Browne, Katharine F.;
Lijun Shang;
Sansom, Mark S. P.;
Baukrowitz, Thomas;
Tucker, Stephen J.

Publication type:

Article

Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17364-5

By:

Kumar, Arvind;
Basak, Sandip;
Rao, Shanlin;
Gicheru, Yvonne;
Mayer, Megan L.;
Sansom, Mark S. P.;
Chakrapani, Sudha

Publication type:

Article

An N-glycan on the C2 domain of JAGGED1 is important for Notch activation.

Published in:

Science Signaling, 2022, v. 15, n. 755, p. 1, doi. 10.1126/scisignal.abo3507

By:

Meng, Yao;
Sanlidag, Sami;
Jensen, Sacha A.;
Burnap, Sean A.;
Struwe, Weston B.;
Larsen, Andreas H.;
Feng, Xinyi;
Mittal, Shruti;
Sansom, Mark S. P.;
Sahlgren, Cecilia;
Handford, Penny A.

Publication type:

Article

Molecular simulation studies of hydrophobic gating in nanopores and ion channels.

Published in:

Biochemical Society Transactions, 2015, v. 43, n. 2, p. 146, doi. 10.1042/BST20140256

By:

Trick, Jemma L.;
Aryal, Prafulla;
Tucker, Stephen J.;
Sansom, Mark S. P.

Publication type:

Article

Interactions of peripheral proteins with model membranes as viewed by molecular dynamics simulations.

Published in:

Biochemical Society Transactions, 2014, v. 42, n. 5, p. 1418, doi. 10.1042/BST20140144

By:

Kalli, Antreas C.;
Sansom, Mark S. P.

Publication type:

Article

Molecular Dynamics Simulations of the Bacterial UraA H+-Uracil Symporter in Lipid Bilayers Reveal a Closed State and a Selective Interaction with Cardiolipin.

Published in:

PLoS Computational Biology, 2015, v. 11, n. 3, p. 1, doi. 10.1371/journal.pcbi.1004123

By:

Kalli, Antreas C.;
Sansom, Mark S. P.;
Reithmeier, Reinhart A. F.

Publication type:

Article

Lipid Clustering Correlates with Membrane Curvature as Revealed by Molecular Simulations of Complex Lipid Bilayers.

Published in:

PLoS Computational Biology, 2014, v. 10, n. 10, p. 1, doi. 10.1371/journal.pcbi.1003911

By:

Koldsø, Heidi;
Shorthouse, David;
Hélie, Jean;
Sansom, Mark S. P.

Publication type:

Article

A Multiscale Approach to Modelling Drug Metabolism by Membrane-Bound Cytochrome P450 Enzymes.

Published in:

PLoS Computational Biology, 2014, v. 10, n. 7, p. 1, doi. 10.1371/journal.pcbi.1003714

By:

Lonsdale, Richard;
Rouse, Sarah L.;
Sansom, Mark S. P.;
Mulholland, Adrian J.

Publication type:

Article

The Free Energy Landscape of Dimerization of a Membrane Protein, NanC.

Published in:

PLoS Computational Biology, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.pcbi.1003417

By:

Dunton, Thomas A.;
Goose, Joseph E.;
Gavaghan, David J.;
Sansom, Mark S. P.;
Osborne, James M.

Publication type:

Article

Conformational Changes in Talin on Binding to Anionic Phospholipid Membranes Facilitate Signaling by Integrin Transmembrane Helices.

Published in:

PLoS Computational Biology, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.pcbi.1003316

By:

Kalli, Antreas C.;
Campbell, Iain D.;
Sansom, Mark S. P.

Publication type:

Article

Reduced Lateral Mobility of Lipids and Proteins in Crowded Membranes.

Published in:

PLoS Computational Biology, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.pcbi.1003033

By:

Goose, Joseph E.;
Sansom, Mark S. P.

Publication type:

Article

Formation of Raft-Like Assemblies within Clusters of Influenza Hemagglutinin Observed by MD Simulations.

Published in:

PLoS Computational Biology, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.pcbi.1003034

By:

Parton, Daniel L.;
Tek, Alex;
Baaden, Marc;
Sansom, Mark S. P.

Publication type:

Article

Mechanism of Bacterial Signal Transduction Revealed by Molecular Dynamics of Tsr Dimers and Trimers of Dimers in Lipid Vesicles.

Published in:

PLoS Computational Biology, 2012, v. 8, n. 9, p. 1, doi. 10.1371/journal.pcbi.1002685

By:

Hall, Benjamin A.;
Armitage, Judith P.;
Sansom, Mark S. P.

Publication type:

Article

Finding a Needle in a Haystack: The Role of Electrostatics in Target Lipid Recognition by PH Domains.

Published in:

PLoS Computational Biology, 2012, v. 8, n. 7, p. 1, doi. 10.1371/journal.pcbi.1002617

By:

Lumb, Craig N.;
Sansom, Mark S. P.

Publication type:

Article

Transmembrane Helix Dynamics of Bacterial Chemoreceptors Supports a Piston Model of Signalling.

Published in:

PLoS Computational Biology, 2011, v. 7, n. 10, p. 1, doi. 10.1371/journal.pcbi.1002204

By:

Hall, Benjamin A.;
Armitage, Judith P.;
Sansom, Mark S. P.

Publication type:

Article

Structure and Dynamics of the Membrane-Bound Cytochrome P450 2C9.

Published in:

PLoS Computational Biology, 2011, v. 7, n. 8, p. 1, doi. 10.1371/journal.pcbi.1002152

By:

Cojocaru, Vlad;
Balali-Mood, Kia;
Sansom, Mark S. P.;
Wade, Rebecca C.

Publication type:

Article

Asymmetric Switching in a Homodimeric ABC Transporter: A Simulation Study.

Published in:

PLoS Computational Biology, 2010, v. 6, n. 4, p. 1, doi. 10.1371/journal.pcbi.1000762

By:

Aittoniemi, Jussi;
de Wet, Heidi;
Ashcroft, Frances M.;
Sansom, Mark S. P.

Publication type:

Article

The Role of C2 Domains in Two Different Phosphatases: PTEN and SHIP2.

Published in:

Membranes, 2023, v. 13, n. 4, p. 408, doi. 10.3390/membranes13040408

By:

John, Laura H.;
Naughton, Fiona B.;
Sansom, Mark S. P.;
Larsen, Andreas Haahr

Publication type:

Article

Specific interactions of peripheral membrane proteins with lipids: what can molecular simulations show us?

Published in:

Bioscience Reports, 2022, v. 42, n. 4, p. 1, doi. 10.1042/BSR20211406

By:

Larsen, Andreas H.;
John, Laura H.;
Sansom, Mark S. P.;
Corey, Robin A.

Publication type:

Article

Coarse-Grain Simulations of the R-SNARE Fusion Protein in its Membrane Environment Detect Long-Lived Conformational Sub-States.

Published in:

ChemPhysChem, 2009, v. 10, n. 9/10, p. 1548, doi. 10.1002/cphc.200900216

By:

Durrieu, Marie-Pierre;
Bond, Peter J.;
Sansom, Mark S. P.;
Lavery, Richard;
Baaden, Marc

Publication type:

Article

Ion channel gates: comparative analysis of energy barriers.

Published in:

European Biophysics Journal, 2009, v. 38, n. 4, p. 347, doi. 10.1007/s00249-008-0377-x

By:

Tai, Kaihsu;
Haider, Shozeb;
Grottesi, Alessandro;
Sansom, Mark S. P.

Publication type:

Article

Molecular dynamics simulations and membrane protein structure quality.

Published in:

European Biophysics Journal, 2008, v. 37, n. 4, p. 403, doi. 10.1007/s00249-007-0225-4

By:

Ivetac, Anthony;
Sansom, Mark S. P.

Publication type:

Article

Outer membrane proteins: comparing X-ray and NMR structures by MD simulations in lipid bilayers.

Published in:

European Biophysics Journal, 2008, v. 37, n. 2, p. 131, doi. 10.1007/s00249-007-0185-8

By:

Cox, Katherine;
Bond, Peter J.;
Grottesi, Alessandro;
Baaden, Marc;
Sansom, Mark S. P.

Publication type:

Article