Found: 27
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Establishment of hyperoxic cell culture system for predicting drug-induced liver injury: reducing accumulated lipids in hepatocytes derived from chimeric mice with humanized liver.
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- Journal of Toxicological Sciences, 2023, v. 48, n. 2, p. 99, doi. 10.2131/jts.48.99
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- Article
Xanthine oxidase and aldehyde oxidase contribute to allopurinol metabolism in rats.
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- Journal of Pharmaceutical Health Care & Sciences, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s40780-022-00262-x
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- Article
Trehalose decreases mRNA and protein expressions of c-Jun and JunB in human cervical cancer HeLa cells.
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- Journal of Biochemistry, 2022, v. 172, n. 3, p. 177, doi. 10.1093/jb/mvac051
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Assessment of metabolic activation of felbamate in chimeric mice with humanized liver in combination with in vitro metabolic assays.
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- Journal of Toxicological Sciences, 2022, v. 47, n. 7, p. 277, doi. 10.2131/jts.47.277
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Prediction of human pharmacokinetics for low‐clearance compounds using pharmacokinetic data from chimeric mice with humanized livers.
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- CTS: Clinical & Translational Science, 2022, v. 15, n. 1, p. 79, doi. 10.1111/cts.13070
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- Article
Treatment with Histone Deacetylase Inhibitor Attenuates Peripheral Inflammation-Induced Cognitive Dysfunction and Microglial Activation: The Effect of SAHA as a Peripheral HDAC Inhibitor.
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- Neurochemical Research, 2021, v. 46, n. 9, p. 2285, doi. 10.1007/s11064-021-03367-1
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- Article
MiT/TFE family members suppress L-leucyl-L-leucine methyl ester-induced cell death.
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- Journal of Toxicological Sciences, 2021, v. 46, n. 3, p. 143, doi. 10.2131/jts.46.143
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- Article
Tributyltin induces epigenetic changes and decreases the expression of nuclear respiratory factor-1.
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- Metallomics, 2018, v. 10, n. 2, p. 337, doi. 10.1039/c7mt00290d
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- Article
Carbofuran causes neuronal vulnerability to glutamate by decreasing GluA2 protein levels in rat primary cortical neurons.
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- Archives of Toxicology, 2018, v. 92, n. 1, p. 401, doi. 10.1007/s00204-017-2018-6
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- Article
Assessment of amiodarone-induced phospholipidosis in chimeric mice with a humanized liver.
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- Journal of Toxicological Sciences, 2017, v. 42, n. 5, p. 589, doi. 10.2131/jts.42.589
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- Article
Developmental changes in drug-metabolizing enzyme expression during metamorphosis of Xenopus tropicalis.
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- Journal of Toxicological Sciences, 2017, v. 42, n. 5, p. 605, doi. 10.2131/jts.42.605
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- Article
Altered expression of the Olr59, Ethe1, and Slc10a2 genes in the liver of F344 rats by neonatal thyroid hormone disruption.
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- Journal of Applied Toxicology, 2017, v. 37, n. 9, p. 1030, doi. 10.1002/jat.3452
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- Article
Low-Concentration Tributyltin Decreases GluR2 Expression via Nuclear Respiratory Factor-1 Inhibition.
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- International Journal of Molecular Sciences, 2017, v. 18, n. 8, p. 1754, doi. 10.3390/ijms18081754
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- Article
Mild MPP<sup>+</sup> exposure-induced glucose starvation enhances autophagosome synthesis and impairs its degradation.
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- Scientific Reports, 2017, p. 46668, doi. 10.1038/srep46668
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- Article
Perfluorooctane sulfonate induces neuronal vulnerability by decreasing GluR2 expression.
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- Archives of Toxicology, 2017, v. 91, n. 2, p. 885, doi. 10.1007/s00204-016-1731-x
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Mild MPP<sup>+</sup> exposure impairs autophagic degradation through a novel lysosomal acidity-independent mechanism.
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- Journal of Neurochemistry, 2016, v. 139, n. 2, p. 294, doi. 10.1111/jnc.13700
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Metabolism of methiocarb and carbaryl by rat and human livers and plasma, and effect on their PXR, CAR and PPARa activities.
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- Journal of Toxicological Sciences, 2016, v. 41, n. 5, p. 677, doi. 10.2131/jts.41.677
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- Article
Mouse aldehyde-oxidase-4 controls diurnal rhythms, fat deposition and locomotor activity.
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- Scientific Reports, 2016, p. 30343, doi. 10.1038/srep30343
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Methoxychlor and fenvalerate induce neuronal death by reducing GluR2 expression.
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- Journal of Toxicological Sciences, 2016, v. 41, n. 2, p. 255, doi. 10.2131/jts.41.255
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- Article
Acetaminophen induces accumulation of functional rat CYP3A via polyubiquitination dysfunction.
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- Scientific Reports, 2016, p. 21373, doi. 10.1038/srep21373
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Detection of metabolic activation leading to drug-induced phospholipidosis in rat hepatocyte spheroids.
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- Journal of Toxicological Sciences, 2016, v. 41, n. 1, p. 155, doi. 10.2131/jts.41.155
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- Article
Endogenous neurotoxic dopamine derivative covalently binds to Parkinson's disease-associated ubiquitin C-terminal hydrolase L1 and alters its structure and function.
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- Journal of Neurochemistry, 2014, v. 130, n. 6, p. 826, doi. 10.1111/jnc.12762
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Chimeric mice transplanted with human hepatocytes as a model for prediction of human drug metabolism and pharmacokinetics.
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- Biopharmaceutics & Drug Disposition, 2014, v. 35, n. 2, p. 71, doi. 10.1002/bdd.1864
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- Article
Involvement of decreased glutamate receptor subunit GluR2 expression in lead-induced neuronal cell death.
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- Journal of Toxicological Sciences, 2013, v. 38, n. 3, p. 513, doi. 10.2131/jts.38.513
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Photodegradation of pharmaceuticals in the aquatic environment by sunlight and UV-A, -B and -C irradiation.
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- Journal of Toxicological Sciences, 2013, v. 38, n. 2, p. 215, doi. 10.2131/jts.38.215
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Comparative Study of the Endocrine-Disrupting Activity of Bisphenol A and 19 Related Compounds.
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- Toxicological Sciences, 2005, v. 84, n. 2, p. 249, doi. 10.1093/toxsci/kfi074
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Estrogenisc Activity of Styrene Oligomers after Metabolic Activation by Rat Liver Microsomes.
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- Environmental Health Perspectives, 2003, v. 111, n. 3, p. 329, doi. 10.1289/ehp.5723
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- Article