Works matching AU Sanger, G. J.

Results: 36

Inhibition of colonic motility and defecation by RS-127445 suggests an involvement of the 5-HT2B receptor in rodent large bowel physiology.

Published in:

2009

By:

Bassil, AK;
Taylor, CM;
Bolton, VJN;
Gray, KM;
Brown, JD;
Cutler, L;
Summerfield, SG;
Bruton, G;
Winchester, WJ;
Lee, K;
Sanger, GJ;
Bassil, A K;
Taylor, C M;
Bolton, V J N;
Gray, K M;
Brown, J D;
Summerfield, S G;
Winchester, W J;
Sanger, G J

Publication type:

journal article

Activation of prostaglandin EP receptors by lubiprostone in rat and human stomach and colon.

Published in:

2008

By:

Bassil, A. K.;
Borman, R. A.;
Jarvie, E. M.;
McArthur-Wilson, R. J.;
Thangiah, R.;
Sung, E. Z. H.;
Lee, K.;
Sanger, G. J.

Publication type:

journal article

Endocannabinoids and the gastrointestinal tract: what are the key questions?

Published in:

British Journal of Pharmacology, 2007, v. 152, n. 5, p. 663, doi. 10.1038/sj.bjp.0707422

By:

Sanger, G. J.

Publication type:

Article

Neuromedin U can exert colon-specific, enteric nerve-mediated prokinetic activity, via a pathway involving NMU1 receptor activation.

Published in:

British Journal of Pharmacology, 2007, v. 150, n. 4, p. 502, doi. 10.1038/sj.bjp.0707004

By:

Dass, N B;
Bassil, A K;
North-Laidler, V J;
Morrow, R;
Aziz, E;
Tuladhar, B R;
Sanger, G J

Publication type:

Article

Differences between the abilities of tegaserod and motilin receptor agonists to stimulate gastric motility in vitro.

Published in:

British Journal of Pharmacology, 2007, v. 150, n. 4, p. 455, doi. 10.1038/sj.bjp.0707118

By:

Jarvie, E M;
North Laidler, V J;
Corcoran, S;
Bassil, A;
Sanger, G J

Publication type:

Article

Little or no ability of obestatin to interact with ghrelin or modify motility in the rat gastrointestinal tract.

Published in:

British Journal of Pharmacology, 2007, v. 150, n. 1, p. 58, doi. 10.1038/sj.bjp.0706969

By:

Bassil, A. K.;
Häglund, Y.;
Brown, J.;
Rudholm, T.;
Hellström, P. M.;
Näslund, E.;
Lee, K.;
Sanger, G. J.

Publication type:

Article

Increased defecation during stress or after 5-hydroxytryptophan: selective inhibition by the 5-HT4 receptor antagonist, SB-207266.

Published in:

British Journal of Pharmacology, 2000, v. 130, n. 3, p. 706, doi. 10.1038/sj.bjp.0703367

By:

Sanger, G J;
Yoshida, M;
Yahyah, M;
Kitazumi, K

Publication type:

Article

The Relationship Between Symptom Improvement and Gastric Emptying in the Treatment of Gastroparesis: Remember the Pharmacology.

Published in:

American Journal of Gastroenterology (Springer Nature), 2014, v. 109, n. 3, p. 444, doi. 10.1038/ajg.2013.432

By:

Sanger, G J

Publication type:

Article

Ghrelin alleviates cancer chemotherapy-associated dyspepsia in rodents.

Published in:

Cancer Chemotherapy & Pharmacology, 2006, v. 58, n. 3, p. 326, doi. 10.1007/s00280-005-0179-0

By:

Liu, Y.-L.;
Malik, N. M.;
Sanger, G. J.;
Andrews, P. L. R.

Publication type:

Article

Farnesoid X receptor ‐ a molecular predictor of weight loss after vertical sleeve gastrectomy?

Published in:

Obesity Science & Practice, 2019, v. 5, n. 3, p. 273, doi. 10.1002/osp4.337

By:

Scott, F.;
Elahi, S.;
Adebibe, M.;
Parampalli, U.;
Mannur, K.;
Góralczyk, A.;
Sanger, G. J.

Publication type:

Article

Regionally dependent neuromuscular functions of motilin and 5- HT4 receptors in human isolated esophageal body and gastric fundus.

Published in:

Neurogastroenterology & Motility, 2014, v. 26, n. 9, p. 1311, doi. 10.1111/nmo.12394

By:

Broad, J.;
Hughes, F.;
Chin‐Aleong, J.;
Sifrim, D.;
Sanger, G. J.

Publication type:

Article

Drugs acting at 5- HT4, D2, motilin, and ghrelin receptors differ markedly in how they affect neuromuscular functions in human isolated stomach.

Published in:

Neurogastroenterology & Motility, 2014, v. 26, n. 6, p. 851, doi. 10.1111/nmo.12338

By:

Broad, J.;
Góralczyk, A.;
Mannur, K.;
Dukes, G. E.;
Sanger, G. J.

Publication type:

Article

Ghrelin and motilin receptor agonists: time to introduce bias into drug design.

Published in:

Neurogastroenterology & Motility, 2014, v. 26, n. 2, p. 149, doi. 10.1111/nmo.12300

By:

Sanger, G. J.

Publication type:

Article

Ghrelin and motilin receptor agonists: a long and winding misconception.

Published in:

Neurogastroenterology & Motility, 2013, v. 25, n. 12, p. 1002, doi. 10.1111/nmo.12241

By:

Sanger, G. J.

Publication type:

Article

GSK962040: a small molecule motilin receptor agonist which increases gastrointestinal motility in conscious dogs.

Published in:

Neurogastroenterology & Motility, 2011, v. 23, n. 10, p. 958, doi. 10.1111/j.1365-2982.2011.01770.x

By:

Leming, S.;
Broad, J.;
Cozens, S. J.;
Otterson, M.;
Winchester, W.;
Lee, K.;
Dukes, G. E.;
Sanger, G. J.

Publication type:

Article

Actions of prolonged ghrelin infusion on gastrointestinal transit and glucose homeostasis in humans.

Published in:

Neurogastroenterology & Motility, 2010, v. 22, n. 6, p. e192, doi. 10.1111/j.1365-2982.2009.01463.x

By:

FALKÉN, Y.;
HELLSTRÖM, P. M.;
SANGER, G. J.;
DEWIT, O.;
DUKES, G.;
GRYBÄCK, P.;
HOLST, J. J.;
NÄSLUND, E.

Publication type:

Article

Translating 5-HT4 receptor pharmacology.

Published in:

Neurogastroenterology & Motility, 2009, v. 21, n. 12, p. 1235, doi. 10.1111/j.1365-2982.2009.01425.x

By:

SANGER, G. J.

Publication type:

Article

5-hydroxyindalpine, an agonist at the putative 5-HT1P receptor, has no activity on human recombinant monoamine receptors but accelerates distension-induced peristalsis in mouse isolated colon.

Published in:

Neurogastroenterology & Motility, 2009, v. 21, n. 7, p. 760, doi. 10.1111/j.1365-2982.2009.01275.x

By:

MITCHELL, N. A.;
PEPPERELL, E.;
OCIEPKA, S.;
BROWN, J. D.;
WITHERINGTON, J.;
TULADHAR, B.;
SANGER, G. J.;
LEE, K.;
CELLEK, S.

Publication type:

Article

GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility.

Published in:

Neurogastroenterology & Motility, 2009, v. 21, n. 6, p. 657, doi. 10.1111/j.1365-2982.2009.01270.x

By:

SANGER, G. J.;
WESTAWAY, S. M.;
BARNES, A. A.;
MACPHERSON, D. T.;
MUIR, A. I.;
JARVIE, E. M.;
BOLTON, V. N.;
CELLEK, S.;
NÄSLUND, E.;
HELLSTRÖM, P. M.;
BORMAN, R. A.;
UNSWORTH, W. P.;
MATTHEWS, K. L.;
LEE, K.

Publication type:

Article

Oral administration of a centrally acting ghrelin receptor agonist to conscious rats triggers defecation.

Published in:

Neurogastroenterology & Motility, 2009, v. 21, n. 1, p. 71, doi. 10.1111/j.1365-2982.2008.01176.x

By:

Shafton, A. D.;
Sanger, G. J.;
Witherington, J.;
Brown, J. D.;
Muir, A.;
Butler, S.;
Abberley, L.;
Shimizu, Y.;
Furness, J. B.

Publication type:

Article

Synergy between 5-HT4 receptor activation and acetylcholinesterase inhibition in human colon and rat forestomach.

Published in:

Neurogastroenterology & Motility, 2008, v. 20, n. 5, p. 539, doi. 10.1111/j.1365-2982.2007.01062.x

By:

Cellek, S.;
Thangiah, R.;
Jarvie, E. M.;
Vivekanandan, S.;
Lalude, O.;
Sanger, G. J.

Publication type:

Article

Development of drugs for gastrointestinal motor disorders: translating science to clinical need.

Published in:

Neurogastroenterology & Motility, 2008, v. 20, n. 3, p. 177, doi. 10.1111/j.1365-2982.2008.01084.x

By:

Sanger, G. J.;
Alpers, D. H.

Publication type:

Article

Effects of NMDA receptor antagonists on visceromotor reflexes and on intestinal motility, in vivo.

Published in:

Neurogastroenterology & Motility, 2007, v. 19, n. 7, p. 617, doi. 10.1111/j.1365-2982.2007.00942.x

By:

Shafton, A. D.;
Bogeski, G.;
Kitchener, P. D.;
Sanger, G. J.;
Furness, J. B.;
Shimizu, Y.

Publication type:

Article

The relationship between the effects of short-chain fatty acids on intestinal motility in vitro and GPR43 receptor activation.

Published in:

Neurogastroenterology & Motility, 2007, v. 19, n. 1, p. 66, doi. 10.1111/j.1365-2982.2006.00853.x

By:

Dass, N. B.;
John, A. K.;
Bassil, A. K.;
Crumbley, C. W.;
Shehee, W. R.;
Maurio, F. P.;
Moore, G. B. T.;
Taylor, C. M.;
Sanger, G. J.

Publication type:

Article

5-HT4 receptor agonists enhance both cholinergic and nitrergic activities in human isolated colon circular muscle.

Published in:

Neurogastroenterology & Motility, 2006, v. 18, n. 9, p. 853, doi. 10.1111/j.1365-2982.2006.00810.x

By:

Cellek, S.;
John, A. K.;
Thangiah, R.;
Dass, N. B.;
Bassil, A. K.;
Jarvie, E. M.;
Lalude, O.;
Vivekanandan, S.;
Sanger, G. J.

Publication type:

Article

The role of endogenous opioids in the control of gastrointestinal motility: predictions fromin vitromodelling.

Published in:

Neurogastroenterology & Motility, 2004, v. 16, p. 38, doi. 10.1111/j.1743-3150.2004.00556.x

By:

Sanger, G. J.;
Tuladhar, B. R.

Publication type:

Article

Effects of the peripherally acting NK3 receptor antagonist, SB-235375, on intestinal and somatic nociceptive responses and on intestinal motility in anaesthetized rats.

Published in:

Neurogastroenterology & Motility, 2004, v. 16, n. 2, p. 223, doi. 10.1111/j.1365-2982.2004.00501.x

By:

Shafton, A. D.;
Bogeski, G.;
Kitchener, P. D.;
Lewis, V. A.;
Sanger, G. J.;
Furness, J. B.

Publication type:

Article

Intestinal anti-nociceptive behaviour of NK3 receptor antagonism in conscious rats: evidence to support a peripheral mechanism of action.

Published in:

Neurogastroenterology & Motility, 2003, v. 15, n. 4, p. 363, doi. 10.1046/j.1365-2982.2003.00420.x

By:

Fioramonti, J.;
Gaultier, E.;
Toulouse, M.;
Sanger, G. J.;
Bueno, L.

Publication type:

Article

Analysis of factors that determine the compliance of rat jejunum to distension in vivo.

Published in:

Neurogastroenterology & Motility, 2003, v. 15, n. 4, p. 417, doi. 10.1046/j.1365-2982.2003.00423.x

By:

Bogeski, G.;
Lean, N. P.;
Kitchener, P. D.;
Timar-Peregrin, A.;
Sanger, G. J.;
Shafton, A. D.;
Furness, J. B.

Publication type:

Article

The relationship between propagated contractions and pseudoaffective changes in blood pressure in response to intestinal distension.

Published in:

Neurogastroenterology & Motility, 2001, v. 13, n. 6, p. 575, doi. 10.1046/j.1365-2982.2001.00289.x

By:

Timar-Peregrin, A.;
Kumano, K.;
Khalil, Z.;
Sanger, G. J.;
Furness, J. B.

Publication type:

Article

Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists.

Published in:

2013

By:

Sanger, G J;
Wang, Y;
Hobson, A;
Broad, J

Publication type:

journal article

Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists.

Published in:

British Journal of Pharmacology, 2013, v. 170, n. 7, p. 1323, doi. 10.1111/bph.12075

By:

Sanger, G J;
Wang, Y;
Hobson, A;
Broad, J

Publication type:

Article

Cholinergic interactions between donepezil and prucalopride in human colon: potential to treat severe intestinal dysmotility.

Published in:

British Journal of Pharmacology, 2013, v. 170, n. 6, p. 1253, doi. 10.1111/bph.12397

By:

Broad, J;
Kung, V W S;
Boundouki, G;
Aziz, Q;
De Maeyer, J H;
Knowles, C H;
Sanger, G J

Publication type:

Article

5-Hydroxytryptamine and functional bowel disorders.

Published in:

Neurogastroenterology & Motility, 1996, v. 8, n. 4, p. 319, doi. 10.1111/j.1365-2982.1996.tb00270.x

By:

SANGER, G. J.

Publication type:

Article

Stimulation of Canine Gastric Motility by BRL 24924, a New Gastric Prokinetic Agent.

Published in:

Neurogastroenterology & Motility, 1990, v. 2, n. 4, p. 281, doi. 10.1111/j.1365-2982.1990.tb00036.x

By:

Bermudez, J.;
Dunbar, A.;
Sanger, G. J.;
Turner, D. H.

Publication type:

Article

Increased plasma ghrelin following infliximab in Crohn’s disease.

Published in:

Alimentary Pharmacology & Therapeutics, 2009, v. 29, n. 1, p. 83, doi. 10.1111/j.1365-2036.2008.03850.x

By:

SUNG, E. Z. H.;
DA SILVA, N. F.;
GOODYEAR, S.;
MCTERNAN, P. G.;
SANGER, G. J.;
NWOKOLO, C. U.

Publication type:

Article

Works matching AU Sanger, G. J.

Inhibition of colonic motility and defecation by RS-127445 suggests an involvement of the 5-HT2B receptor in rodent large bowel physiology.

Activation of prostaglandin EP receptors by lubiprostone in rat and human stomach and colon.

Endocannabinoids and the gastrointestinal tract: what are the key questions?

Neuromedin U can exert colon-specific, enteric nerve-mediated prokinetic activity, via a pathway involving NMU<sub>1</sub> receptor activation.

Differences between the abilities of tegaserod and motilin receptor agonists to stimulate gastric motility in vitro.

Little or no ability of obestatin to interact with ghrelin or modify motility in the rat gastrointestinal tract.

Increased defecation during stress or after 5-hydroxytryptophan: selective inhibition by the 5-HT<sub>4</sub> receptor antagonist, SB-207266.

The Relationship Between Symptom Improvement and Gastric Emptying in the Treatment of Gastroparesis: Remember the Pharmacology.

Ghrelin alleviates cancer chemotherapy-associated dyspepsia in rodents.

Farnesoid X receptor ‐ a molecular predictor of weight loss after vertical sleeve gastrectomy?

Regionally dependent neuromuscular functions of motilin and 5- HT<sub>4</sub> receptors in human isolated esophageal body and gastric fundus.

Drugs acting at 5- HT<sub>4</sub>, D<sub>2</sub>, motilin, and ghrelin receptors differ markedly in how they affect neuromuscular functions in human isolated stomach.

Ghrelin and motilin receptor agonists: time to introduce bias into drug design.

Ghrelin and motilin receptor agonists: a long and winding misconception.

GSK962040: a small molecule motilin receptor agonist which increases gastrointestinal motility in conscious dogs.

Actions of prolonged ghrelin infusion on gastrointestinal transit and glucose homeostasis in humans.

Translating 5-HT<sub>4</sub> receptor pharmacology.

5-hydroxyindalpine, an agonist at the putative 5-HT<sub>1P</sub> receptor, has no activity on human recombinant monoamine receptors but accelerates distension-induced peristalsis in mouse isolated colon.

GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility.

Oral administration of a centrally acting ghrelin receptor agonist to conscious rats triggers defecation.

Synergy between 5-HT<sub>4</sub> receptor activation and acetylcholinesterase inhibition in human colon and rat forestomach.

Development of drugs for gastrointestinal motor disorders: translating science to clinical need.

Effects of NMDA receptor antagonists on visceromotor reflexes and on intestinal motility, in vivo.

The relationship between the effects of short-chain fatty acids on intestinal motility in vitro and GPR43 receptor activation.

5-HT<sub>4</sub> receptor agonists enhance both cholinergic and nitrergic activities in human isolated colon circular muscle.

The role of endogenous opioids in the control of gastrointestinal motility: predictions fromin vitromodelling.

Effects of the peripherally acting NK<sub>3</sub> receptor antagonist, SB-235375, on intestinal and somatic nociceptive responses and on intestinal motility in anaesthetized rats.

Intestinal anti-nociceptive behaviour of NK<sub>3</sub> receptor antagonism in conscious rats: evidence to support a peripheral mechanism of action.

Analysis of factors that determine the compliance of rat jejunum to distension in vivo.

The relationship between propagated contractions and pseudoaffective changes in blood pressure in response to intestinal distension.

Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists.

Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists.

Cholinergic interactions between donepezil and prucalopride in human colon: potential to treat severe intestinal dysmotility.

5-Hydroxytryptamine and functional bowel disorders.

Stimulation of Canine Gastric Motility by BRL 24924, a New Gastric Prokinetic Agent.

Increased plasma ghrelin following infliximab in Crohn’s disease.