Works by Sang Geon Kim

Results: 81

Gα13 ablation reprograms myofibers to oxidative phenotype and enhances whole-body metabolism.

Published in:

2017

By:

Ja Hyun Koo;
Tae Hyun Kim;
Shi-Young Park;
Min Sung Joo;
Chang Yeob Han;
Cheol Soo Choi;
Sang Geon Kim;
Koo, Ja Hyun;
Kim, Tae Hyun;
Park, Shi-Young;
Joo, Min Sung;
Han, Chang Yeob;
Choi, Cheol Soo;
Kim, Sang Geon

Publication type:

journal article

Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1,3-dimethyluric acid formation.

Published in:

Journal of Pharmacy & Pharmacology, 2002, v. 54, n. 12, p. 1687, doi. 10.1211/002235702333

By:

Yu, Su Yeon;
Chung, Hye Chin;
Kim, Eun Jung;
Kim, So Hee;
Lee, Inchull;
Kim, Sang Geon;
Lee, Myung Gull

Publication type:

Article

Body Weight as a Determining Factor in the Predominance of Adverse Drug Reactions Induced by Fixed-Dose Adalimumab Injections in Female Patients in a Korean Hospital Setting.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 2, p. 461, doi. 10.3390/jcm9020461

By:

Kim, Kwi Suk;
Choi, Young Hee;
Moon, Aree;
Kim, Sang Geon

Publication type:

Article

Ginsenoside Rg3 inhibits phenylephrine-induced vascular contraction through induction of nitric oxide synthase.

Published in:

British Journal of Pharmacology, 2003, v. 140, n. 4, p. 661, doi. 10.1038/sj.bjp.0705490

By:

Nak Doo Kim;
Eun Mi Kim;
Keon Wook Kang;
Min Kyung Cho;
So Yeon Choi;
Sang Geon Kim

Publication type:

Article

Inhibition of lipopolysaccaride-inducible nitric oxide synthase, TNF-α and COX-2 expression by sauchinone effects on I-κBα phosphorylation, C/EBP and AP-1 activation.

Published in:

British Journal of Pharmacology, 2003, v. 139, n. 1, p. 11, doi. 10.1038/sj.bjp.0705231

By:

Ae Kyung Lee;
Sang Hyun Sung;
Young Choong Kim;
Sang Geon Kim

Publication type:

Article

NRF2-mediated SIRT3 induction protects hepatocytes from ER stress-induced liver injury.

Published in:

FASEB Journal, 2022, v. 36, n. 3, p. 1, doi. 10.1096/fj.202101470R

By:

Ayoung Kim;
Ja Hyun Koo;
Jung Min Lee;
Min Sung Joo;
Tae Hyun Kim;
Hyunsung Kim;
Dae Won Jun;
Sang Geon Kim

Publication type:

Article

Expression of Cytochrome P-450s and Glutathione S-Transferases in the Rat Liver during Water Deprivation: Effects of Glucose Supplementation.

Published in:

Journal of Applied Toxicology, 2001, v. 21, n. 2, p. 123, doi. 10.1002/jat.734

By:

Sang Geon Kim;
Eun Jung Kim;
Yoon Gyoon Kim;
Myung Gull Lee

Publication type:

Article

Hepatic Gα13 ablation shifts region-specific colonic inflammatory status by modulating the bile acid synthetic pathway in mice.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-70254-4

By:

Kwon, Soon Jae;
Kim, Yun Seok;
Tak, Jihoon;
Lee, Sang Gil;
Lee, Eun Byul;
Kim, Sang Geon

Publication type:

Article

A TRPC3/6 Channel Inhibitor Promotes Arteriogenesis after Hind-Limb Ischemia.

Published in:

Cells (2073-4409), 2022, v. 11, n. 13, p. N.PAG, doi. 10.3390/cells11132041

By:

Shimauchi, Tsukasa;
Numaga-Tomita, Takuro;
Kato, Yuri;
Morimoto, Hiroyuki;
Sakata, Kosuke;
Matsukane, Ryosuke;
Nishimura, Akiyuki;
Nishiyama, Kazuhiro;
Shibuta, Atsushi;
Horiuchi, Yutoku;
Kurose, Hitoshi;
Kim, Sang Geon;
Urano, Yasuteru;
Ohshima, Takashi;
Nishida, Motohiro

Publication type:

Article

Roles of X-box binding protein 1 in liver pathogenesis.

Published in:

Clinical & Molecular Hepatology, 2025, v. 31, n. 1, p. 1, doi. 10.3350/cmh.2024.0441

By:

Jihoon Tak;
Yun Seok Kim;
Sang Geon Kim

Publication type:

Article

Endoplasmic reticulum stress and autophagy dysregulation in alcoholic and non-alcoholic liver diseases.

Published in:

Clinical & Molecular Hepatology, 2020, v. 26, n. 4, p. 715, doi. 10.3350/cmh.2020.0173

By:

Yun Seok Kim;
Sang Geon Kim

Publication type:

Article

Anti-Inflammatory and Pain-Relieving Effects of Arnica Extract Hydrogel Patch in Carrageenan-Induced Inflammation and Hot Plate Pain Models.

Published in:

Pharmaceutics, 2025, v. 17, n. 2, p. 171, doi. 10.3390/pharmaceutics17020171

By:

Lee, Sang Gil;
Lee, Eun Byul;
Nam, Tack Soo;
You, Sunho;
Im, Dahye;
Kim, Kyusun;
Gu, Bonseung;
Nam, Ga-young;
Lee, Hyerim;
Kwon, Soon Jae;
Kim, Yun Seok;
Kim, Sang Geon

Publication type:

Article

Gα12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration.

Published in:

2018

By:

Tae Hyun Kim;
Yoon Mee Yang;
Chang Yeob Han;
Ja Hyun Koo;
Hyunhee Oh;
Su Sung Kim;
Byoung Hoon You;
Young Hee Choi;
Tae-Sik Park;
Chang Ho Lee;
Hitoshi Kurose;
Mazen Noureddin;
Ekihiro Seki;
Yu-Jui Yvonne Wan;
Cheol Soo Choi;
Sang Geon Kim;
Kim, Tae Hyun;
Yang, Yoon Mee;
Han, Chang Yeob;
Koo, Ja Hyun

Publication type:

journal article

DA-125, a novel anthracycline derivative showing high-affinity DNA binding and topoisomerase II inhibitory activities, exerts cytotoxicity via c-Jun N-terminal kinase pathway.

Published in:

Cancer Chemotherapy & Pharmacology, 2001, v. 47, n. 6, p. 511, doi. 10.1007/s002800100276

By:

Sang Geon Kim;
Mina Sung;
Keon Wook Kang;
Soon Hoe Kim;
Moon Ho Son;
Won Bae Kim

Publication type:

Article

Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes.

Published in:

Journal of Cachexia, Sarcopenia & Muscle, 2021, v. 12, n. 6, p. 1669, doi. 10.1002/jcsm.12777

By:

Kim, Ayoung;
Koo, Ja Hyun;
Jin, Xing;
Kim, Wondong;
Park, Shi‐Young;
Park, Sunghyouk;
Rhee, Eugene P.;
Choi, Cheol Soo;
Kim, Sang Geon

Publication type:

Article

Regulation of thymus-dependent and thymus-independent production of immunoglobulin G subclasses by Galpha12 and Galpha13.

Published in:

Journal of Molecular Signaling, 2008, v. 3, p. 1, doi. 10.1186/1750-2187-3-12

By:

Song Jin Lee;
Woo Hyung Lee;
Chang Ho Lee;
Sang Geon Kim

Publication type:

Article

Gα12 regulates osteoclastogenesis by modulating NFATc1 expression.

Published in:

Journal of Cellular & Molecular Medicine, 2018, v. 22, n. 2, p. 849, doi. 10.1111/jcmm.13370

By:

Song, Min‐Kyoung;
Park, Cheolkyu;
Lee, Yong Deok;
Kim, Haemin;
Kim, Min Kyung;
Kwon, Jun‐Oh;
Koo, Ja Hyun;
Joo, Min Sung;
Kim, Sang Geon;
Kim, Hong‐Hee

Publication type:

Article

AMPK-Dependent Metabolic Regulation by PPAR Agonists.

Published in:

PPAR Research, 2010, p. 1, doi. 10.1155/2010/549101

By:

Woo Hyung Lee;
Sang Geon Kim

Publication type:

Article

Intestinal Inflammation and Regeneration–Interdigitating Processes Controlled by Dietary Lipids in Inflammatory Bowel Disease.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 2, p. 1311, doi. 10.3390/ijms25021311

By:

Kwon, Soon Jae;
Khan, Muhammad Sohaib;
Kim, Sang Geon

Publication type:

Article

Dysregulated Liver Metabolism and Polycystic Ovarian Syndrome.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 8, p. 7454, doi. 10.3390/ijms24087454

By:

Khan, Muhammad Sohaib;
Kim, Hee-Sun;
Kim, Ranhee;
Yoon, Sang Ho;
Kim, Sang Geon

Publication type:

Article

Knockout of Purinergic P2Y 6 Receptor Fails to Improve Liver Injury and Inflammation in Non-Alcoholic Steatohepatitis.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 3800, doi. 10.3390/ijms24043800

By:

Nishiyama, Kazuhiro;
Ariyoshi, Kohei;
Nishimura, Akiyuki;
Kato, Yuri;
Mi, Xinya;
Kurose, Hitoshi;
Kim, Sang Geon;
Nishida, Motohiro

Publication type:

Article

Hypergravity Load Modulates Acetaminophen Nephrotoxicity via Endoplasmic Reticulum Stress in Association with Hepatic microRNA-122 Expression.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4901, doi. 10.3390/ijms22094901

By:

Wu, Hong-Min;
Lee, Sang-Gil;
Oh, Choong-Sik;
Kim, Sang-Geon;
Grimm, Daniela

Publication type:

Article

Gα12/13 signaling in metabolic diseases.

Published in:

Experimental & Molecular Medicine EMM, 2020, v. 52, n. 6, p. 896, doi. 10.1038/s12276-020-0454-5

By:

Yang, Yoon Mee;
Kuen, Da-Sol;
Chung, Yeonseok;
Kurose, Hitoshi;
Kim, Sang Geon

Publication type:

Article

Efficacy and tolerability of diphenyl-dimethyl-dicarboxylate plus garlic oil in patients with chronic hepatitis.

Published in:

International Journal of Clinical Pharmacology & Therapeutics, 2012, v. 50, n. 11, p. 778, doi. 10.5414/CP201746

By:

Min Ho Lee;
Young Mi Kim;
Sang Geon Kim

Publication type:

Article

Plk2-mediated phosphorylation and translocalization of Nrf2 activates anti-inflammation through p53/Plk2/p21cip1 signaling in acute kidney injury.

Published in:

Cell Biology & Toxicology, 2023, v. 39, n. 4, p. 1509, doi. 10.1007/s10565-022-09741-1

By:

Kim, Da-Eun;
Byeon, Hye Eun;
Kim, Dae-Hoon;
Kim, Sang Geon;
Yim, Hyungshin

Publication type:

Article

DA6034 promotes gastric epithelial cell migration and wound-healing through the mTOR pathway.

Published in:

Journal of Gastroenterology & Hepatology, 2012, v. 27, n. 2, p. 397, doi. 10.1111/j.1440-1746.2011.06873.x

By:

Kim, Young Woo;
Lee, Woo Hyung;
Choi, Seul Min;
Seo, Yoon Young;
Ahn, Byoung Ok;
Kim, Soon Hoe;
Kim, Sang Geon

Publication type:

Article

Mitigation of carbon tetrachloride-induced hepatic injury by methylene blue, a repurposed drug, is mediated by dual inhibition of GSK3β downstream of PKA.

Published in:

2014

By:

Wu, Hong Min;
Lee, Chan Gyu;
Hwang, Se Jin;
Kim, Sang Geon

Publication type:

journal article

Mitigation of carbon tetrachloride-induced hepatic injury by methylene blue, a repurposed drug, is mediated by dual inhibition of GSK3β downstream of PKA.

Published in:

British Journal of Pharmacology, 2014, v. 171, n. 11, p. 2790, doi. 10.1111/bph.12637

By:

Wu, Hong Min;
Lee, Chan Gyu;
Hwang, Se Jin;
Kim, Sang Geon

Publication type:

Article

An active metabolite of oltipraz (M2) increases mitochondrial fuel oxidation and inhibits lipogenesis in the liver by dually activating AMPK.

Published in:

2013

By:

Kim, Tae Hyun;
Eom, Jeong Sik;
Lee, Chan Gyu;
Yang, Yoon Mee;
Lee, Yong Sup;
Kim, Sang Geon

Publication type:

journal article

An active metabolite of oltipraz ( M2) increases mitochondrial fuel oxidation and inhibits lipogenesis in the liver by dually activating AMPK.

Published in:

British Journal of Pharmacology, 2013, v. 168, n. 7, p. 1647, doi. 10.1111/bph.12057

By:

Kim, Tae Hyun;
Eom, Jeong Sik;
Lee, Chan Gyu;
Yang, Yoon Mee;
Lee, Yong Sup;
Kim, Sang Geon

Publication type:

Article

Nrf2-mediated liver protection by sauchinone, an antioxidant lignan, from acetaminophen toxicity through the PKCδ-GSK3β pathway.

Published in:

2011

By:

Kay, Hee Yeon;
Kim, Young Woo;
Ryu, Da Hye;
Sung, Sang Hyun;
Hwang, Se Jin;
Kim, Sang Geon

Publication type:

journal article

Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D.

Published in:

Nature Communications, 2022, v. 13, p. 1, doi. 10.1038/s41467-022-33749-0

By:

Kim, Yun Seok;
Ko, Bongsub;
Kim, Da Jung;
Tak, Jihoon;
Han, Chang Yeob;
Cho, Joo-Youn;
Kim, Won;
Kim, Sang Geon

Publication type:

Article

Metformin Prevents an Adaptive Increase in GSH and Induces Apoptosis Under the Conditions of GSH Deficiency in H4IIE Cells.

Published in:

Journal of Toxicology & Environmental Health: Part A, 2007, v. 70, n. 15/16, p. 1371, doi. 10.1080/15287390701434430

By:

Eun Ju Bae;
Min Joo Cho;
Sang Geon Kim

Publication type:

Article

DEPRENYL, A THERAPEUTIC AGENT FOR PARKINSON’S DISEASE, INHIBITS ARSENIC TOXICITY POTENTIATED BY GSH DEPLETION VIA INHIBITION OF JNK ACTIVATION.

Published in:

Journal of Toxicology & Environmental Health: Part A, 2004, v. 67, n. 23/24, p. 2013, doi. 10.1080/15287390490514732

By:

Sang Geon Kim;
Chang Ho Lee;
Jeong Weon Park

Publication type:

Article

AMPK Facilitates Nuclear Accumulation of Nrf2 by Phosphorylating at Serine 550.

Published in:

Molecular & Cellular Biology, 2016, v. 36, n. 14, p. 1931, doi. 10.1128/MCB.00118-16

By:

Min Sung Joo;
Won Dong Kim;
Ki Young Lee;
Ji Hyun Kim;
Ja Hyun Koo;
Sang Geon Kim

Publication type:

Article

Role of Gα12 and Gα13 as Novel Switches for the Activity of Nrf2, a Key Antioxidative Transcription Factor.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 17, p. 22, doi. 10.1128/MCB.02065-06

By:

Min Kyung Cho;
Won Dong Kim;
Sung Hwan Ki;
Jong-IK Hwang;
Sangdun Choi;
Chang Ho Lee;
Sang Geon Kim

Publication type:

Article

Etoposide Induces Necrosis Through p53-Mediated Antiapoptosis in Human Kidney Proximal Tubule Cells.

Published in:

Toxicological Sciences, 2015, v. 148, n. 1, p. 204, doi. 10.1093/toxsci/kfv182

By:

Hyuk-Kwon Kwon;
Hyeon-Jun Shin;
Jae-Hyeok Lee;
Seol-Hee Park;
Min-Cheol Kwon;
Panneerselvam, Suresh;
Chan Gyu Lee;
Sang Geon Kim;
Jae-Ho Kim;
Sangdun Choi

Publication type:

Article

PI3K, RSK, and mTOR Signal Networks for the GST Gene Regulation.

Published in:

Toxicological Sciences, 2007, v. 96, n. 2, p. 206

By:

Sang Geon Kim

Publication type:

Article

Inhibition of dynamin‐related protein 1‐filamin interaction improves systemic glucose metabolism.

Published in:

British Journal of Pharmacology, 2024, v. 181, n. 21, p. 4328, doi. 10.1111/bph.16487

By:

Kato, Yuri;
Ariyoshi, Kohei;
Nohara, Yasunobu;
Matsunaga, Naoya;
Shimauchi, Tsukasa;
Shindo, Naoya;
Nishimura, Akiyuki;
Mi, Xinya;
Kim, Sang Geon;
Ide, Tomomi;
Kawanishi, Eiji;
Ojida, Akio;
Nakashima, Naoki;
Mori, Yasuo;
Nishida, Motohiro

Publication type:

Article

Hemin, an iron-binding porphyrin, inhibits HIF-1α induction through its binding with heat shock protein 90.

Published in:

International Journal of Cancer, 2012, v. 130, n. 3, p. 716, doi. 10.1002/ijc.26075

By:

Lee, Jung Min;
Lee, Woo Hyung;
Kay, Hee Yeon;
Kim, Eun-sook;
Moon, Aree;
Kim, Sang Geon

Publication type:

Article

Dual regulation of NEMO by Nrf2 and miR-125a inhibits ferroptosis and protects liver from endoplasmic reticulum stress-induced injury.

Published in:

Theranostics, 2024, v. 14, n. 5, p. 1841, doi. 10.7150/thno.89703

By:

Jihoon Tak;
Min Sung Joo;
Yun Seok Kim;
Hyun Woo Park;
Chang Hoon Lee;
Gil-Chun Park;
Shin Hwang;
Sang Geon Kim

Publication type:

Article

Gα12 overexpression in hepatocytes by ER stress exacerbates acute liver injury via ROCK1-mediated miR-15a and ALOX12 dysregulation.

Published in:

Theranostics, 2022, v. 12, n. 4, p. 1570, doi. 10.7150/thno.67722

By:

Jihoon Tak;
Yun Seok Kim;
Tae Hyun Kim;
Gil-Chun Park;
Shin Hwang;
Sang Geon Kim

Publication type:

Article

Hepcidin inhibits Smad3 phosphorylation in hepatic stellate cells by impeding ferroportin-mediated regulation of Akt.

Published in:

Nature Communications, 2016, v. 7, n. 12, p. 13817, doi. 10.1038/ncomms13817

By:

Han, Chang Yeob;
Koo, Ja Hyun;
Kim, Sung Hoon;
Gardenghi, Sara;
Rivella, Stefano;
Strnad, Pavel;
Hwang, Se Jin;
Kim, Sang Geon

Publication type:

Article

Non-alcoholic fatty liver disease and liver secretome.

Published in:

Archives of Pharmacal Research, 2022, v. 45, n. 12, p. 938, doi. 10.1007/s12272-022-01419-w

By:

Khan, Muhammad Sohaib;
Lee, Choongho;
Kim, Sang Geon

Publication type:

Article

Role of non-coding RNAs in liver disease progression to hepatocellular carcinoma.

Published in:

Archives of Pharmacal Research, 2019, v. 42, n. 1, p. 48, doi. 10.1007/s12272-018-01104-x

By:

Heo, Mi Jeong;
Yun, Jessica;
Kim, Sang Geon

Publication type:

Article

Identifying drugs needing pharmacogenetic monitoring in a Korean hospital.

Published in:

American Journal of Health-System Pharmacy, 2007, v. 64, n. 2, p. 166, doi. 10.2146/ajhp050490

By:

Young Mi Kim;
Seung Hee Yoo;
Rae Young Kang;
Min Jung Kim;
Yoon Young Bae;
Yeon Kyung Lee;
Su Jin Jeon;
Kung Ju Chon;
Sang Mi Shin;
Sang Geon Kim;
Kyoung Ho Park;
In Ja Son

Publication type:

Article

Sex-biased differences in the correlation between epithelial-to-mesenchymal transition-associated genes in cancer cell lines.

Published in:

Oncology Letters, 2019, v. 18, n. 6, p. 6852, doi. 10.3892/ol.2019.11016

By:

Kim, Sun Young;
Lee, Seungeun;
Lee, Eunhye;
Lim, Hyesol;
Shin, Ji Yoon;
Jung, Joohee;
Kim, Sang Geon;
Moon, Aree

Publication type:

Article

Gα12 and endoplasmic reticulum stress-mediated pyroptosis in a single cycle of dextran sulfate-induced mouse colitis.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-56685-z

By:

Tak, Jihoon;
An, Quanxi;
Lee, Sang Gil;
Lee, Chang Hoon;
Kim, Sang Geon

Publication type:

Article

Nrf2-lncRNA controls cell fate by modulating p53-dependent Nrf2 activation as an miRNA sponge for Plk2 and p21cip1.

Published in:

FASEB Journal, 2019, v. 33, n. 7, p. 7953, doi. 10.1096/fj.201802744R

By:

Min Sung Joo;
Sol-Bi Shin;
Eun Jung Kim;
Ja Hyun Koo;
Hyungshin Yim;
Sang Geon Kim

Publication type:

Article

S1P receptor‐1 and USP4 induced by microRNA‐148a deregulation facilitate liver cancer progression (766.1).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.766.1

By:

Heo, Mi Jeong;
Kim, Young Mi;
Koo, Ja Hyun;
Kim, Sang Geon

Publication type:

Article