Works matching AU Sang Geon Kim

Results: 81

Gα13 ablation reprograms myofibers to oxidative phenotype and enhances whole-body metabolism.

Published in:

2017

By:

Ja Hyun Koo;
Tae Hyun Kim;
Shi-Young Park;
Min Sung Joo;
Chang Yeob Han;
Cheol Soo Choi;
Sang Geon Kim;
Koo, Ja Hyun;
Kim, Tae Hyun;
Park, Shi-Young;
Joo, Min Sung;
Han, Chang Yeob;
Choi, Cheol Soo;
Kim, Sang Geon

Publication type:

journal article

Drug-induced Hyperbilirubinemia and the Clinical Influencing Factors.

Published in:

Drug Metabolism Reviews, 2008, v. 40, n. 4, p. 511, doi. 10.1080/03602530802341133

By:

Ah, Young-Mi;
Kim, Young-Mi;
Kim, Min-Jung;
Choi, Young Hee;
Park, Kyoung-Ho;
Son, In-Ja;
Kim, Sang Geon

Publication type:

Article

Sex-biased differences in the correlation between epithelial-to-mesenchymal transition-associated genes in cancer cell lines.

Published in:

Oncology Letters, 2019, v. 18, n. 6, p. 6852, doi. 10.3892/ol.2019.11016

By:

Kim, Sun Young;
Lee, Seungeun;
Lee, Eunhye;
Lim, Hyesol;
Shin, Ji Yoon;
Jung, Joohee;
Kim, Sang Geon;
Moon, Aree

Publication type:

Article

Hypoxia-inducible factor-1α inhibition by a pyrrolopyrazine metabolite of oltipraz as a consequence of microRNAs 199a-5p and 20a induction.

Published in:

Carcinogenesis, 2012, v. 33, n. 3, p. 661, doi. 10.1093/carcin/bgr320

By:

Kang, Seul Gi;
Lee, Woo Hyung;
Lee, Young Hun;
Lee, Yong Sup;
Kim, Sang Geon

Publication type:

Article

Gα12/13 inhibition enhances the anticancer effect of bortezomib through PSMB5 downregulation.

Published in:

Carcinogenesis, 2010, v. 31, n. 7, p. 1230, doi. 10.1093/carcin/bgq097

By:

Yoon Mee Yang;
Lee, Sanghwan;
Chang Won Nam;
Ji Hee Ha;
Jayaraman, Muralidharan;
Dhanasekaran, Danny N.;
Chang Ho Lee;
Mi-Kyoung Kwak;
Sang Geon Kim

Publication type:

Article

Regulation of thymus-dependent and thymus-independent production of immunoglobulin G subclasses by Galpha12 and Galpha13.

Published in:

Journal of Molecular Signaling, 2008, v. 3, p. 1, doi. 10.1186/1750-2187-3-12

By:

Song Jin Lee;
Woo Hyung Lee;
Chang Ho Lee;
Sang Geon Kim

Publication type:

Article

NRF2-mediated SIRT3 induction protects hepatocytes from ER stress-induced liver injury.

Published in:

FASEB Journal, 2022, v. 36, n. 3, p. 1, doi. 10.1096/fj.202101470R

By:

Ayoung Kim;
Ja Hyun Koo;
Jung Min Lee;
Min Sung Joo;
Tae Hyun Kim;
Hyunsung Kim;
Dae Won Jun;
Sang Geon Kim

Publication type:

Article

Nrf2-lncRNA controls cell fate by modulating p53-dependent Nrf2 activation as an miRNA sponge for Plk2 and p21cip1.

Published in:

FASEB Journal, 2019, v. 33, n. 7, p. 7953, doi. 10.1096/fj.201802744R

By:

Min Sung Joo;
Sol-Bi Shin;
Eun Jung Kim;
Ja Hyun Koo;
Hyungshin Yim;
Sang Geon Kim

Publication type:

Article

S1P receptor‐1 and USP4 induced by microRNA‐148a deregulation facilitate liver cancer progression (766.1).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.766.1

By:

Heo, Mi Jeong;
Kim, Young Mi;
Koo, Ja Hyun;
Kim, Sang Geon

Publication type:

Article

miR‐125b transcriptionally induced by Nrf2 inhibits AhR repressor for AhR activation (663.12).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.663.12

By:

Joo, Min Sung;
Lee, Chan Gyu;
Koo, Ja Hyun;
Kim, Sang Geon

Publication type:

Article

Hypoxia inducible factor‐1α inhibition by protopophyrin IX through miR‐199a‐5p upregulation in mesenchymal‐typed hepatocellular carcinoma (1052.7).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.1052.7

By:

Lee, Jung Min;
Lee, Woo Hyung;
Kim, Sang Geon

Publication type:

Article

Sphingosine‐1‐phosphate (S1P) Signaling for Breast Cell Invasion.

Published in:

FASEB Journal, 2013, v. 27, p. 598.2, doi. 10.1096/fasebj.27.1_supplement.598.2

By:

Moon, Aree;
Kim, Eun‐Sook;
Kim, Jong‐Sook;
Kim, Sang Geon;
Hwang, Sejin;
Lee, Chang Ho

Publication type:

Article

JNK1 phosphorylation of HNF4α represses miR‐122, which causes PTP1B induction.

Published in:

FASEB Journal, 2013, v. 27, p. 1169.9, doi. 10.1096/fasebj.27.1_supplement.1169.9

By:

Yang, Yoon Mee;
Seo, So Yeon;
Kim, Tae Hyun;
Kim, Sang Geon

Publication type:

Article

Role of Gα12/Gα13 as novel switches for the activity of Nrf2.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1181, doi. 10.1096/fasebj.21.6.a1181-b

By:

Won Dong Kim;
Min Kyung Cho;
Chang Ho Lee;
Sang Geon Kim

Publication type:

Article

Gα12 specifically regulates COX-2 induction by sphingosine 1-phosphate.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A978, doi. 10.1096/fasebj.21.6.a978-d

By:

Sung Hwan Ki;
Min Jung Choi;
Chang Ho Lee;
Sang Geon Kim

Publication type:

Article

Role of Gα12 family members in mdm4-mediated p53 expression.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A431, doi. 10.1096/fasebj.21.5.a431-b

By:

Sang Geon Kim;
Mi-Sung Kim;
Sang Min Lee;
Won Dong Kim;
Moon, Aree;
Chang Ho Lee

Publication type:

Article

A role of activating transcription factor (ATF)2 in transcriptional activation of matrix metalloproteinase (MMP)-2 in human breast epithelial cells.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A388, doi. 10.1096/fasebj.21.5.a388

By:

Hyun Song;
Sung Hwan Ki;
Sang Geon Kim;
Aree Moon

Publication type:

Article

Oltipraz regenerates cirrhotic liver through CCAAT/enhancer binding protein‐mediated stellate cell inactivation.

Published in:

FASEB Journal, 2002, v. 16, n. 14, p. 1988, doi. 10.1096/fj.02-0406fje

By:

Wook Kang, Keon;
Gyoon Kim, Yoon;
Kyong Cho, Min;
Kyung Bae, Soo;
Won Kim, Choon;
Gull Lee, Myung;
Geon Kim, Sang

Publication type:

Article

Efficacy and tolerability of diphenyl-dimethyl-dicarboxylate plus garlic oil in patients with chronic hepatitis.

Published in:

International Journal of Clinical Pharmacology & Therapeutics, 2012, v. 50, n. 11, p. 778, doi. 10.5414/CP201746

By:

Min Ho Lee;
Young Mi Kim;
Sang Geon Kim

Publication type:

Article

Expression of Cytochrome P-450s and Glutathione S-Transferases in the Rat Liver during Water Deprivation: Effects of Glucose Supplementation.

Published in:

Journal of Applied Toxicology, 2001, v. 21, n. 2, p. 123, doi. 10.1002/jat.734

By:

Sang Geon Kim;
Eun Jung Kim;
Yoon Gyoon Kim;
Myung Gull Lee

Publication type:

Article

Mitigation of carbon tetrachloride-induced hepatic injury by methylene blue, a repurposed drug, is mediated by dual inhibition of GSK3β downstream of PKA.

Published in:

2014

By:

Wu, Hong Min;
Lee, Chan Gyu;
Hwang, Se Jin;
Kim, Sang Geon

Publication type:

journal article

Mitigation of carbon tetrachloride-induced hepatic injury by methylene blue, a repurposed drug, is mediated by dual inhibition of GSK3β downstream of PKA.

Published in:

British Journal of Pharmacology, 2014, v. 171, n. 11, p. 2790, doi. 10.1111/bph.12637

By:

Wu, Hong Min;
Lee, Chan Gyu;
Hwang, Se Jin;
Kim, Sang Geon

Publication type:

Article

An active metabolite of oltipraz (M2) increases mitochondrial fuel oxidation and inhibits lipogenesis in the liver by dually activating AMPK.

Published in:

2013

By:

Kim, Tae Hyun;
Eom, Jeong Sik;
Lee, Chan Gyu;
Yang, Yoon Mee;
Lee, Yong Sup;
Kim, Sang Geon

Publication type:

journal article

An active metabolite of oltipraz ( M2) increases mitochondrial fuel oxidation and inhibits lipogenesis in the liver by dually activating AMPK.

Published in:

British Journal of Pharmacology, 2013, v. 168, n. 7, p. 1647, doi. 10.1111/bph.12057

By:

Kim, Tae Hyun;
Eom, Jeong Sik;
Lee, Chan Gyu;
Yang, Yoon Mee;
Lee, Yong Sup;
Kim, Sang Geon

Publication type:

Article

Nrf2-mediated liver protection by sauchinone, an antioxidant lignan, from acetaminophen toxicity through the PKCδ-GSK3β pathway.

Published in:

2011

By:

Kay, Hee Yeon;
Kim, Young Woo;
Ryu, Da Hye;
Sung, Sang Hyun;
Hwang, Se Jin;
Kim, Sang Geon

Publication type:

journal article

Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D.

Published in:

Nature Communications, 2022, v. 13, p. 1, doi. 10.1038/s41467-022-33749-0

By:

Kim, Yun Seok;
Ko, Bongsub;
Kim, Da Jung;
Tak, Jihoon;
Han, Chang Yeob;
Cho, Joo-Youn;
Kim, Won;
Kim, Sang Geon

Publication type:

Article

Overproduction of inter-α-trypsin inhibitor heavy chain 1 after loss of Gα13 in liver exacerbates systemic insulin resistance in mice.

Published in:

Science Translational Medicine, 2019, v. 11, n. 513, p. 1, doi. 10.1126/scitranslmed.aan4735

By:

Kim, Tae Hyun;
Koo, Ja Hyun;
Heo, Mi Jeong;
Han, Chang Yeob;
Kim, Yong-In;
Park, Shi-Young;
Cho, Il Je;
Lee, Chang Ho;
Choi, Cheol Soo;
Lee, Jung Weon;
Kim, Won;
Cho, Je-Yoel;
Kim, Sang Geon

Publication type:

Article

Non-alcoholic fatty liver disease and liver secretome.

Published in:

Archives of Pharmacal Research, 2022, v. 45, n. 12, p. 938, doi. 10.1007/s12272-022-01419-w

By:

Khan, Muhammad Sohaib;
Lee, Choongho;
Kim, Sang Geon

Publication type:

Article

Role of non-coding RNAs in liver disease progression to hepatocellular carcinoma.

Published in:

Archives of Pharmacal Research, 2019, v. 42, n. 1, p. 48, doi. 10.1007/s12272-018-01104-x

By:

Heo, Mi Jeong;
Yun, Jessica;
Kim, Sang Geon

Publication type:

Article

Induction of the Alcohol Inducible Form of Cytochrome P-450 By Nitrogen-Containing Heterocycles: Effects on Pyridine It-Oxide Production.

Published in:

Drug Metabolism Reviews, 1989, v. 20, n. 2/4, p. 781, doi. 10.3109/03602538909103578

By:

Novak, Raymond f.;
Kaul, Karen l.;
Kim, Sang Geon

Publication type:

Article

Essential role of phosphatidylinositol 3-kinase-dependent CCAAT/enhancer binding protein beta activation in the induction of glutathione S-transferase by oltipraz.

Published in:

2003

By:

Kang, Keon Wook;
Cho, Il Je;
Lee, Chang Ho;
Kim, Sang Geon

Publication type:

journal article

Essential Role of Phosphatidylinositol 3-Kinase-Dependent CCAAT/Enhancer Binding Protein Β Activation in the Induction of Glutathione S-Transferase by Oltipraz.

Published in:

JNCI: Journal of the National Cancer Institute, 2003, v. 95, n. 1, p. 53, doi. 10.1093/jnci/95.1.53

By:

Keon Wook Kang;
Il Je Cho;
Chang Ho Lee;
Sang Geon Kim

Publication type:

Article

Corrigendum: A load of mice to hypergravity causes AMPKα repression with liver injury, which is overcome by preconditioning loads via Nrf2.

Published in:

Scientific Reports, 2016, p. 34677, doi. 10.1038/srep34677

By:

Lee, Sang Gil;
Lee, Chan Gyu;
Wu, Hong Min;
Oh, Choong Sik;
Chung, So Won;
Kim, Sang Geon

Publication type:

Article

DA6034 promotes gastric epithelial cell migration and wound-healing through the mTOR pathway.

Published in:

Journal of Gastroenterology & Hepatology, 2012, v. 27, n. 2, p. 397, doi. 10.1111/j.1440-1746.2011.06873.x

By:

Kim, Young Woo;
Lee, Woo Hyung;
Choi, Seul Min;
Seo, Yoon Young;
Ahn, Byoung Ok;
Kim, Soon Hoe;
Kim, Sang Geon

Publication type:

Article

Ginsenoside Rg3 inhibits phenylephrine-induced vascular contraction through induction of nitric oxide synthase.

Published in:

British Journal of Pharmacology, 2003, v. 140, n. 4, p. 661, doi. 10.1038/sj.bjp.0705490

By:

Nak Doo Kim;
Eun Mi Kim;
Keon Wook Kang;
Min Kyung Cho;
So Yeon Choi;
Sang Geon Kim

Publication type:

Article

Inhibition of lipopolysaccaride-inducible nitric oxide synthase, TNF-α and COX-2 expression by sauchinone effects on I-κBα phosphorylation, C/EBP and AP-1 activation.

Published in:

British Journal of Pharmacology, 2003, v. 139, n. 1, p. 11, doi. 10.1038/sj.bjp.0705231

By:

Ae Kyung Lee;
Sang Hyun Sung;
Young Choong Kim;
Sang Geon Kim

Publication type:

Article

Hemin, an iron-binding porphyrin, inhibits HIF-1α induction through its binding with heat shock protein 90.

Published in:

International Journal of Cancer, 2012, v. 130, n. 3, p. 716, doi. 10.1002/ijc.26075

By:

Lee, Jung Min;
Lee, Woo Hyung;
Kay, Hee Yeon;
Kim, Eun-sook;
Moon, Aree;
Kim, Sang Geon

Publication type:

Article

Discovery of an integrative network of microRNAs and transcriptomics changes for acute kidney injury.

Published in:

Kidney International, 2014, v. 86, n. 5, p. 943, doi. 10.1038/ki.2014.117

By:

Lee, Chan Gyu;
Kim, Jin Geol;
Kim, Hyun Joo;
Kwon, Hyuk-Kwon;
Cho, Il Je;
Choi, Dal Woong;
Lee, Woo Hyung;
Kim, Won Dong;
Hwang, Se Jin;
Choi, Sangdun;
Kim, Sang Geon

Publication type:

Article

Gα12/13 signaling in metabolic diseases.

Published in:

Experimental & Molecular Medicine EMM, 2020, v. 52, n. 6, p. 896, doi. 10.1038/s12276-020-0454-5

By:

Yang, Yoon Mee;
Kuen, Da-Sol;
Chung, Yeonseok;
Kurose, Hitoshi;
Kim, Sang Geon

Publication type:

Article

AMPK Facilitates Nuclear Accumulation of Nrf2 by Phosphorylating at Serine 550.

Published in:

Molecular & Cellular Biology, 2016, v. 36, n. 14, p. 1931, doi. 10.1128/MCB.00118-16

By:

Min Sung Joo;
Won Dong Kim;
Ki Young Lee;
Ji Hyun Kim;
Ja Hyun Koo;
Sang Geon Kim

Publication type:

Article

Role of Gα12 and Gα13 as Novel Switches for the Activity of Nrf2, a Key Antioxidative Transcription Factor.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 17, p. 22, doi. 10.1128/MCB.02065-06

By:

Min Kyung Cho;
Won Dong Kim;
Sung Hwan Ki;
Jong-IK Hwang;
Sangdun Choi;
Chang Ho Lee;
Sang Geon Kim

Publication type:

Article

Glucocorticoid Receptor (GR)-Associated SMRT Binding to C/EBPβ TAD and Nrf2 Neh4/5: Role of SMRT Recruited to GR in GSTA2 Gene Repression.

Published in:

Molecular & Cellular Biology, 2005, v. 25, n. 10, p. 4150, doi. 10.1128/MCB.25.10.4150-4165.2005

By:

Sung Hwan Ki;
Il Je Cho;
Dal Woong Choi;
Sang Geon Kim

Publication type:

Article

Gα12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration.

Published in:

2018

By:

Tae Hyun Kim;
Yoon Mee Yang;
Chang Yeob Han;
Ja Hyun Koo;
Hyunhee Oh;
Su Sung Kim;
Byoung Hoon You;
Young Hee Choi;
Tae-Sik Park;
Chang Ho Lee;
Hitoshi Kurose;
Mazen Noureddin;
Ekihiro Seki;
Yu-Jui Yvonne Wan;
Cheol Soo Choi;
Sang Geon Kim;
Kim, Tae Hyun;
Yang, Yoon Mee;
Han, Chang Yeob;
Koo, Ja Hyun

Publication type:

journal article

Hepatic Gα13 ablation shifts region-specific colonic inflammatory status by modulating the bile acid synthetic pathway in mice.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-70254-4

By:

Kwon, Soon Jae;
Kim, Yun Seok;
Tak, Jihoon;
Lee, Sang Gil;
Lee, Eun Byul;
Kim, Sang Geon

Publication type:

Article

Gα12 and endoplasmic reticulum stress-mediated pyroptosis in a single cycle of dextran sulfate-induced mouse colitis.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-56685-z

By:

Tak, Jihoon;
An, Quanxi;
Lee, Sang Gil;
Lee, Chang Hoon;
Kim, Sang Geon

Publication type:

Article

Roles of X-box binding protein 1 in liver pathogenesis.

Published in:

Clinical & Molecular Hepatology, 2025, v. 31, n. 1, p. 1, doi. 10.3350/cmh.2024.0441

By:

Jihoon Tak;
Yun Seok Kim;
Sang Geon Kim

Publication type:

Article

Endoplasmic reticulum stress and autophagy dysregulation in alcoholic and non-alcoholic liver diseases.

Published in:

Clinical & Molecular Hepatology, 2020, v. 26, n. 4, p. 715, doi. 10.3350/cmh.2020.0173

By:

Yun Seok Kim;
Sang Geon Kim

Publication type:

Article

ERα inhibits mesenchymal and amoeboidal movement of liver cancer cell via Gα12.

Published in:

International Journal of Cancer, 2022, v. 150, n. 10, p. 1690, doi. 10.1002/ijc.33929

By:

Yun, Jessica;
Kim, Yun Seok;
Heo, Mi Jeong;
Kim, Min Joo;
Moon, Aree;
Kim, Sang Geon

Publication type:

Article

UBC12‐mediated SREBP‐1 neddylation worsens metastatic tumor prognosis.

Published in:

International Journal of Cancer, 2020, v. 147, n. 9, p. 2550, doi. 10.1002/ijc.33113

By:

Heo, Mi Jeong;
Kang, Sung Hyun;
Kim, Yun Seok;
Lee, Jung Min;
Yu, Jinha;
Kim, Hong‐Rae;
Lim, Hyesol;
Kim, Kyoung Mee;
Jung, Joohee;
Jeong, Lak Shin;
Moon, Aree;
Kim, Sang Geon

Publication type:

Article

Expression of microsomal epoxide hydrolase is elevated in Alzheimer's hippocampus and induced by exogenous β-amyloid and trimethyl-tin.

Published in:

European Journal of Neuroscience, 2006, v. 23, n. 8, p. 2027, doi. 10.1111/j.1460-9568.2006.04724.x

By:

Liu, Mei;
Sun, Anyang;
Shin, Eun‐Joo;
Liu, Xianxi;
Kim, Sang‐Geon;
Runyons, Cecil R.;
Markesbery, William;
Kim, Hyoung‐Chun;
Bing, Guoying

Publication type:

Article