Works matching AU Sandtner, Walter

Results: 27

Modeling of SGLT1 in Reconstituted Systems Reveals Apparent Ion-Dependencies of Glucose Uptake and Strengthens the Notion of Water-Permeable Apo States.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.874472

By:

Barta, Thomas;
Sandtner, Walter;
Wachlmayr, Johann;
Hannesschlaeger, Christof;
Ebert, Andrea;
Speletz, Armin;
Horner, Andreas

Publication type:

Article

Cooperative Binding of Substrate and Ions Drives Forward Cycling of the Human Creatine Transporter-1.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.919439

By:

Farr, Clemens V.;
El-Kasaby, Ali;
Erdem, Fatma A.;
Sucic, Sonja;
Freissmuth, Michael;
Sandtner, Walter

Publication type:

Article

Modeling of SGLT1 in Reconstituted Systems Reveals Apparent Ion-Dependencies of Glucose Uptake and Strengthens the Notion of Water-Permeable Apo States.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.874472

By:

Barta, Thomas;
Sandtner, Walter;
Wachlmayr, Johann;
Hannesschlaeger, Christof;
Ebert, Andrea;
Speletz, Armin;
Horner, Andreas

Publication type:

Article

Optimizing the Substrate Uptake Rate of Solute Carriers.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.817886

By:

Schicker, Klaus;
Farr, Clemens V.;
Boytsov, Danila;
Freissmuth, Michael;
Sandtner, Walter

Publication type:

Article

The Environment Shapes the Inner Vestibule of LeuT.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 11, p. 1, doi. 10.1371/journal.pcbi.1005197

By:

Sohail, Azmat;
Jayaraman, Kumaresan;
Venkatesan, Santhoshkannan;
Gotfryd, Kamil;
Daerr, Markus;
Gether, Ulrik;
Loland, Claus J.;
Wanner, Klaus T.;
Freissmuth, Michael;
Sitte, Harald H.;
Sandtner, Walter;
Stockner, Thomas

Publication type:

Article

Kinetic Models of Secondary Active Transporters.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 21, p. 5365, doi. 10.3390/ijms20215365

By:

Burtscher, Verena;
Schicker, Klaus;
Freissmuth, Michael;
Sandtner, Walter

Publication type:

Article

Handling of intracellular K<sup>+</sup> determines voltage dependence of plasmalemmal monoamine transporter function.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.67996

By:

Bhat, Shreyas;
Niello, Marco;
Schicker, Klaus;
Pif, Christian;
Sitte, Harald H.;
Freissmuth, Michael;
Sandtner, Walter

Publication type:

Article

A quantitative model of amphetamine action on the 5- HT transporter.

Published in:

British Journal of Pharmacology, 2014, v. 171, n. 4, p. 1007, doi. 10.1111/bph.12520

By:

Sandtner, Walter;
Schmid, Diethart;
Schicker, Klaus;
Gerstbrein, Klaus;
Koenig, Xaver;
Mayer, Felix P;
Boehm, Stefan;
Freissmuth, Michael;
Sitte, Harald H

Publication type:

Article

The Amino Terminus of LeuT Changes Conformation in an Environment Sensitive Manner.

Published in:

Neurochemical Research, 2020, v. 45, n. 6, p. 1387, doi. 10.1007/s11064-019-02928-9

By:

Khan, Jawad A.;
Sohail, Azmat;
Jayaraman, Kumaresan;
Szöllősi, Dániel;
Sandtner, Walter;
Sitte, Harald H.;
Stockner, Thomas

Publication type:

Article

LRET-based intramolecular distance measurements in LeuT<sub>Aa</sub>.

Published in:

2011

By:

Sohail, Azmat;
Stolt-Bergner, Peggy;
Ecker, Gerhard F;
Freissmuth, Michael;
Stockner, Thomas;
Sitte, Harald H;
Sandtner, Walter

Publication type:

Abstract

The anti-addictive drug ibogaine modulates voltage-gated ion channels and may trigger cardiac arrhythmias.

Published in:

2011

By:

Kovar, Michael;
Koenig, Xaver;
Mike, Ágnes;
Cervenka, René;
Lukács, Péter;
Todt, Hannes;
Sandtner,, Walter;
Hilber, Karlheinz

Publication type:

Abstract

Luminescence resonance energy transfer-based intramolecular distance measurements in leucine transporter from Aquifex aeolicus.

Published in:

2010

By:

Sohail, Azmat;
Stolt-Bergner, Peggy;
Ecker, Gerhard F.;
Freissmuth, Michael;
Sitte, Harald;
Sandtner, Walter

Publication type:

Abstract

A relationship between membrane permeability of amphetamines and serotonin efflux via serotonin transporters.

Published in:

BMC Pharmacology, 2009, v. 9, p. 1, doi. 10.1186/1471-2210-9-S2-A37

By:

Sandtner, Walter;
Gerstbrein, Klaus;
Sitte, Harald H.

Publication type:

Article

Mutations in the amino-terminus impair amphetamine-induced efflux by inducing inward-facing conformations of the serotonin transporter.

Published in:

BMC Pharmacology, 2009, v. 9, p. 1, doi. 10.1186/1471-2210-9-S2-A12

By:

Sucic, Sonja;
Dallinger, Stephan;
Zdrazil, Barbara;
Kudlacek, Oliver;
Sandtner, Walter;
Ecker, Gerhard F;
Freissmuth, Michael;
Sitte, Harald H.

Publication type:

Article

Entropic barrier of water permeation through single-file channels.

Published in:

Communications Chemistry, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42004-023-00919-0

By:

Wachlmayr, Johann;
Fläschner, Gotthold;
Pluhackova, Kristyna;
Sandtner, Walter;
Siligan, Christine;
Horner, Andreas

Publication type:

Article

'Second-Generation' Mephedrone Analogs, 4-MEC and 4-MePPP, Differentially Affect Monoamine Transporter Function.

Published in:

Neuropsychopharmacology, 2015, v. 40, n. 6, p. 1321, doi. 10.1038/npp.2014.325

By:

Saha, Kusumika;
Partilla, John S;
Lehner, Kurt R;
Seddik, Amir;
Stockner, Thomas;
Holy, Marion;
Sandtner, Walter;
Ecker, Gerhard F;
Sitte, Harald H;
Baumann, Michael H

Publication type:

Article

Evidence for a Role of Transporter-Mediated Currents in the Depletion of Brain Serotonin Induced by Serotonin Transporter Substrates.

Published in:

Neuropsychopharmacology, 2014, v. 39, n. 6, p. 1355, doi. 10.1038/npp.2013.331

By:

Baumann, Michael H;
Bulling, Simon;
Benaderet, Tova S;
Saha, Kusumika;
Ayestas, Mario A;
Partilla, John S;
Ali, Syed F;
Stockner, Thomas;
Rothman, Richard B;
Sandtner, Walter;
Sitte, Harald H

Publication type:

Article

The synthetic cathinones, butylone and pentylone, are stimulants that act as dopamine transporter blockers but 5-HT transporter substrates.

Published in:

Psychopharmacology, 2019, v. 236, n. 3, p. 953, doi. 10.1007/s00213-018-5075-5

By:

Saha, Kusumika;
Li, Yang;
Holy, Marion;
Lehner, Kurt R.;
Bukhari, Mohammad O.;
Partilla, John S.;
Sandtner, Walter;
Sitte, Harald H.;
Baumann, Michael H.

Publication type:

Article

Careful Examination of a Novel Azobenzene Paroxetine Derivative and Its Interactions With Biogenic Amine Transporters.

Published in:

Journal of Neurochemistry, 2025, v. 169, n. 4, p. 1, doi. 10.1111/jnc.70068

By:

Dreier, Dominik;
Belleza, Oliver John V.;
Schlögl, Katharina;
Kickinger, Stefanie;
Hellsberg, Eva;
Mayer, Felix P.;
Sandtner, Walter;
Mikšovsky, Philipp;
Schittmayer, Matthias;
Hu, Yuntao;
Jäntsch, Kathrin;
Holy, Marion;
Ecker, Gerhard F.;
Sitte, Harald H.;
Mihovilovic, Marko D.

Publication type:

Article

Refinement of the Central Steps of Substrate Transport by the Aspartate Transporter GltPh: Elucidating the Role of the Na2 Sodium Binding Site.

Published in:

PLoS Computational Biology, 2015, v. 11, n. 10, p. 1, doi. 10.1371/journal.pcbi.1004551

By:

Venkatesan, SanthoshKannan;
Saha, Kusumika;
Sohail, Azmat;
Sandtner, Walter;
Freissmuth, Michael;
Ecker, Gerhard F.;
Sitte, Harald H.;
Stockner, Thomas

Publication type:

Article

Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites.

Published in:

Angewandte Chemie, 2016, v. 128, n. 5, p. 1751, doi. 10.1002/ange.201508755

By:

Zhu, Rong;
Sinwel, Doris;
Hasenhuetl, Peter S.;
Saha, Kusumika;
Kumar, Vivek;
Zhang, Peng;
Rankl, Christian;
Holy, Marion;
Sucic, Sonja;
Kudlacek, Oliver;
Karner, Andreas;
Sandtner, Walter;
Stockner, Thomas;
Gruber, Hermann J.;
Freissmuth, Michael;
Newman, Amy Hauck;
Sitte, Harald H.;
Hinterdorfer, Peter

Publication type:

Article

Lanthanide resonance energy transfer‐based distance measurements in the mammalian glutamate transporter excitatory amino acid transporter 3 (1064.12).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.1064.12

By:

Saha, Kusumika;
Venkatesan, Santhosh;
Sohail, Azmat;
Stockner, Thomas;
Sandtner, Walter;
Ecker, Gerhard;
Sitte, Harald

Publication type:

Article

A mechanism of uncompetitive inhibition of the serotonin transporter.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.82641

By:

Bhat, Shreyas;
El-Kasaby, Ali;
Kasture, Ameya;
Boytsov, Danila;
Reichelt, Julian B.;
Hummel, Thomas;
Sucic, Sonja;
Pifl, Christian;
Freissmuth, Michael;
Sandtner, Walter

Publication type:

Article

Editorial: Combining computational and experimental approaches to characterize ion channels and transporters.

Published in:

Frontiers in Physiology, 2023, p. 1, doi. 10.3389/fphys.2023.1320336

By:

Fahlke, Christoph;
Machtens, Jan-Philipp;
Sandtner, Walter;
Schicker, Klaus;
Han Sun

Publication type:

Article

Anti-addiction drug ibogaine inhibits hERG channels: a cardiac arrhythmia risk.

Published in:

Addiction Biology, 2014, v. 19, n. 2, p. 237, doi. 10.1111/j.1369-1600.2012.00447.x

By:

Koenig, Xaver;
Kovar, Michael;
Boehm, Stefan;
Sandtner, Walter;
Hilber, Karlheinz

Publication type:

Article

Descriptors of Secondary Active Transporter Function and How They Relate to Partial Reactions in the Transport Cycle.

Published in:

Membranes, 2021, v. 11, n. 3, p. 178, doi. 10.3390/membranes11030178

By:

Schicker, Klaus;
Bhat, Shreyas;
Farr, Clemens;
Burtscher, Verena;
Horner, Andreas;
Freissmuth, Michael;
Sandtner, Walter;
Sarkadi, Balazs

Publication type:

Article

Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 5, p. 1719, doi. 10.1002/anie.201508755

By:

Zhu, Rong;
Sinwel, Doris;
Hasenhuetl, Peter S.;
Saha, Kusumika;
Kumar, Vivek;
Zhang, Peng;
Rankl, Christian;
Holy, Marion;
Sucic, Sonja;
Kudlacek, Oliver;
Karner, Andreas;
Sandtner, Walter;
Stockner, Thomas;
Gruber, Hermann J.;
Freissmuth, Michael;
Hauck Newman, Amy;
Sitte, Harald H.;
Hinterdorfer, Peter

Publication type:

Article