Works by Sandholm, Niina

Results: 53

Relationship between sRAGE and obesity in individuals with type 1 diabetes during a median follow-up of 6.3 years.

Published in:

Diabetologia, 2025, v. 68, n. 8, p. 1657, doi. 10.1007/s00125-025-06440-4

By:

Adeshara, Krishna;
Parente, Erika B.;
Harjutsalo, Valma;
Lehto, Markku;
Sandholm, Niina;
Groop, Per-Henrik

Publication type:

Article

Genome-wide characterization of 54 urinary metabolites reveals molecular impact of kidney function.

Published in:

Nature Communications, 2025, v. 16, p. 1, doi. 10.1038/s41467-024-55182-1

By:

Valo, Erkka;
Richmond, Anne;
Mutter, Stefan;
Dahlström, Emma H.;
Campbell, Archie;
Porteous, David J.;
Wilson, James F.;
FinnDiane Study Group;
Groop, Per-Henrik;
Hayward, Caroline;
Sandholm, Niina

Publication type:

Article

Differential metabolomic signatures of declining renal function in Types 1 and 2 diabetes.

Published in:

Nephrology Dialysis Transplantation, 2021, v. 36, n. 10, p. 1859, doi. 10.1093/ndt/gfaa175

By:

Manca, Maria Laura;
Solini, Anna;
Haukka, Jani K;
Sandholm, Niina;
Forsblom, Carol;
Groop, Per-Henrik;
Ferrannini, Ele

Publication type:

Article

Whole-genome sequencing identifies variants in ANK1, LRRN1, HAS1, and other genes and regulatory regions for stroke in type 1 diabetes.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-61840-7

By:

Antikainen, Anni A.;
Haukka, Jani K.;
Kumar, Anmol;
Syreeni, Anna;
Hägg-Holmberg, Stefanie;
Ylinen, Anni;
Kilpeläinen, Elina;
Kytölä, Anastasia;
Palotie, Aarno;
Putaala, Jukka;
Thorn, Lena M.;
Harjutsalo, Valma;
Groop, Per-Henrik;
Sandholm, Niina

Publication type:

Article

Genetic and epigenetic background of diabetic kidney disease.

Published in:

Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1163001

By:

Sandholm, Niina;
Dahlström, Emma H.;
Groop, Per-Henrik

Publication type:

Article

Genetic Risk Score Enhances Coronary Artery Disease Risk Prediction in Individuals With Type 1 Diabetes.

Published in:

2022

By:

Lithovius, Raija;
Antikainen, Anni A.;
Mutter, Stefan;
Valo, Erkka;
Forsblom, Carol;
Harjutsalo, Valma;
Sandholm, Niina;
Groop, Per-Henrik

Publication type:

journal article

Response to Comment on Parente et al. The Relationship Between Body Fat Distribution and Nonalcoholic Fatty Liver in Adults With Type 1 Diabetes. Diabetes Care 2021;44:1706-1713.

Published in:

Diabetes Care, 2022, v. 45, n. 1, p. e8, doi. 10.2337/dci21-0045

By:

Parente, Erika B.;
Dahlström, Emma H.;
Harjutsalo, Valma;
Inkeri, Jussi;
Mutter, Stefan;
Forsblom, Carol;
Sandholm, Niina;
Gordin, Daniel;
Groop, Per-Henrik

Publication type:

Article

The Relationship Between Body Fat Distribution and Nonalcoholic Fatty Liver in Adults With Type 1 Diabetes.

Published in:

2021

By:

Parente, Erika B.;
Dahlström, Emma H.;
Harjutsalo, Valma;
Inkeri, Jussi;
Mutter, Stefan;
Forsblom, Carol;
Sandholm, Niina;
Gordin, Daniel;
Groop, Per-Henrik;
FinnDiane Study Group

Publication type:

journal article

Variations in Risk of End-Stage Renal Disease and Risk of Mortality in an International Study of Patients With Type 1 Diabetes and Advanced Nephropathy.

Published in:

2019

By:

Skupien, Jan;
Smiles, Adam M.;
Valo, Erkka;
Ahluwalia, Tarunveer S.;
Gyorgy, Beata;
Sandholm, Niina;
Croall, Stephanie;
Lajer, Maria;
McDonnell, Kevin;
Forsblom, Carol;
Harjutsalo, Valma;
Marre, Michel;
Galecki, Andrzej T.;
Tregouet, David-Alexandre;
Chun Yi Wu;
Mychaleckyj, Josyf C.;
Nickerson, Helen;
Pragnell, Marlon;
Rich, Stephen S.;
Pezzolesi, Marcus G.

Publication type:

journal article

Kidney Injury Molecule-1 and the Loss of Kidney Function in Diabetic Nephropathy: A Likely Causal Link in Patients With Type 1 Diabetes.

Published in:

Diabetes Care, 2015, v. 38, n. 6, p. 1130, doi. 10.2337/dc14-2330

By:

Panduru, Nicolae M.;
Sandholm, Niina;
Forsblom, Carol;
Saraheimo, Markku;
Dahlström, Emma H.;
Thorn, Lena M.;
Gordin, Daniel;
Tolonen, Nina;
Wadén, Johan;
Harjutsalo, Valma;
Bierhaus, Angelika;
Humpert, Per M.;
Groop, Per-Henrik

Publication type:

Article

New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes.

Published in:

PLoS Genetics, 2012, v. 8, n. 9, p. 1, doi. 10.1371/journal.pgen.1002921

By:

Sandholm, Niina;
Salem, Rany M.;
Mcknight, Amy Jayne;
Brennan, Eoin P.;
Forsblom, Carol;
Isakova, Tamara;
McKay, Gareth J.;
Williams, Winfred W.;
Sadlier, Denise M.;
Mäkinen, Ville-Petteri;
Swan, Elizabeth J.;
Palmer, Cameron;
Boright, Andrew P.;
Ahlqvist, Emma;
Deshmukh, Harshal A.;
Keller, Benjamin J.;
Huateng Huang;
Ahola, Aila J.;
Fagerholm, Emma;
Gordin, Daniel

Publication type:

Article

Thymocyte regulatory variant alters transcription factor binding and protects from type 1 diabetes in infants.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-18296-4

By:

Sandholm, Niina;
Rubio García, Arcadio;
Pekalski, Marcin L.;
Inshaw, Jamie R. J.;
Cutler, Antony J.;
Todd, John A.

Publication type:

Article

Differential Methylation of Telomere-Related Genes Is Associated with Kidney Disease in Individuals with Type 1 Diabetes.

Published in:

Genes, 2023, v. 14, n. 5, p. 1029, doi. 10.3390/genes14051029

By:

Hill, Claire;
Duffy, Seamus;
Kettyle, Laura M.;
McGlynn, Liane;
Sandholm, Niina;
Salem, Rany M.;
Thompson, Alex;
Swan, Elizabeth J.;
Kilner, Jill;
Rossing, Peter;
Shiels, Paul G.;
Lajer, Maria;
Groop, Per-Henrik;
Maxwell, Alexander Peter;
McKnight, Amy Jayne

Publication type:

Article

Genome-wide association study on coronary artery disease in type 1 diabetes suggests beta-defensin 127 as a risk locus.

Published in:

Cardiovascular Research, 2021, v. 117, n. 2, p. 600, doi. 10.1093/cvr/cvaa045

By:

Antikainen, Anni A V;
Sandholm, Niina;
Trégouët, David-Alexandre;
Charmet, Romain;
McKnight, Amy Jayne;
Ahluwalia, Tarunveer S;
Syreeni, Anna;
Valo, Erkka;
Forsblom, Carol;
Gordin, Daniel;
Harjutsalo, Valma;
Hadjadj, Samy;
Maxwell, Alexander P;
Rossing, Peter;
Groop, Per-Henrik

Publication type:

Article

Osteopontin Is a Strong Predictor of Incipient Diabetic Nephropathy, Cardiovascular Disease, and All-Cause Mortality in Patients With Type 1 Diabetes.

Published in:

Diabetes Care, 2014, v. 37, n. 9, p. 2593, doi. 10.2337/dc14-0065

By:

Gordin, Daniel;
Forsblom, Carol;
Panduru, Nicolae M.;
Thomas, Merlin C.;
Bjerre, Mette;
Soro-Paavonen, Aino;
Tolonen, Nina;
Sandholm, Niina;
Flyvbjerg, Allan;
Harjutsalo, Valma;
Groop, Per-Henrik

Publication type:

Article

Different Lipid Variables Predict Incident Coronary Artery Disease in Patients With Type 1 Diabetes With or Without Diabetic Nephropathy: The FinnDiane Study.

Published in:

Diabetes Care, 2014, v. 37, n. 8, p. 2374, doi. 10.2337/dc13-2873

By:

Tolonen, Nina;
Forsblom, Carol;
Mäkinen, Ville-Petteri;
Harjutsalo, Valma;
Gordin, Daniel;
Feodoroff, Maija;
Sandholm, Niina;
Thorn, Lena M.;
Waden, Johan;
Taskinen, Marja-Riitta;
Groop, Per-Henrik

Publication type:

Article

Whole-exome sequencing identifies novel protein-altering variants associated with serum apolipoprotein and lipid concentrations.

Published in:

Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01135-6

By:

Sandholm, Niina;
Hotakainen, Ronja;
Haukka, Jani K.;
Jansson Sigfrids, Fanny;
Dahlström, Emma H.;
Antikainen, Anni A.;
Valo, Erkka;
Syreeni, Anna;
Kilpeläinen, Elina;
Kytölä, Anastasia;
Palotie, Aarno;
Harjutsalo, Valma;
Forsblom, Carol;
Groop, Per-Henrik

Publication type:

Article

Long‐term favorable prognosis in late onset dominant distal titinopathy: Tibial muscular dystrophy.

Published in:

European Journal of Neurology, 2023, v. 30, n. 4, p. 1080, doi. 10.1111/ene.15688

By:

Lillback, Victoria;
Savarese, Marco;
Sandholm, Niina;
Hackman, Peter;
Udd, Bjarne

Publication type:

Article

<i>CD2AP</i> is associated with end-stage renal disease in patients with type 1 diabetes.

Published in:

Acta Diabetologica, 2013, v. 50, n. 6, p. 887, doi. 10.1007/s00592-013-0475-9

By:

Hyvönen, Mervi E.;
Ihalmo, Pekka;
Sandholm, Niina;
Stavarachi, Monica;
Forsblom, Carol;
McKnight, Amy Jayne;
Lajer, Maria;
Maestroni, Anna;
Lewis, Gareth;
Tarnow, Lise;
Maestroni, Silvia;
Zerbini, Gianpaolo;
Parving, Hans-Henrik;
Maxwell, Alexander P.;
Groop, Per-Henrik;
Lehtonen, Sanna

Publication type:

Article

Genetic Profile of Endotoxemia Reveals an Association With Thromboembolism and Stroke.

Published in:

2021

By:

Leskelä, Jaakko;
Toppila, Iiro;
Härma, Mari-Anne;
Palviainen, Teemu;
Salminen, Aino;
Sandholm, Niina;
Pietiäinen, Milla;
Kopra, Elisa;
Pais de Barros, Jean-Paul;
Lassenius, Mariann I.;
Kumar, Anmol;
Harjutsalo, Valma;
Roslund, Kajsa;
Forsblom, Carol;
Loukola, Anu;
Havulinna, Aki S.;
Lagrost, Laurent;
Salomaa, Veikko;
Groop, Per-Henrik;
Perola, Markus

Publication type:

journal article

Whole-exome and whole-genome sequencing of 1064 individuals with type 1 diabetes reveals novel genes for diabetic kidney disease.

Published in:

Diabetologia, 2024, v. 67, n. 11, p. 2494, doi. 10.1007/s00125-024-06241-1

By:

Haukka, Jani K.;
Antikainen, Anni A.;
Valo, Erkka;
Syreeni, Anna;
Dahlström, Emma H.;
Lin, Bridget M.;
Franceschini, Nora;
Krolewski, Andrzej S.;
Harjutsalo, Valma;
Groop, Per-Henrik;
Sandholm, Niina

Publication type:

Article

Genome-wide meta-analysis and omics integration identifies novel genes associated with diabetic kidney disease.

Published in:

Diabetologia, 2022, v. 65, n. 9, p. 1495, doi. 10.1007/s00125-022-05735-0

By:

Sandholm, Niina;
Cole, Joanne B.;
Nair, Viji;
Sheng, Xin;
Liu, Hongbo;
Ahlqvist, Emma;
van Zuydam, Natalie;
Dahlström, Emma H.;
Fermin, Damian;
Smyth, Laura J.;
Salem, Rany M.;
Forsblom, Carol;
Valo, Erkka;
Harjutsalo, Valma;
Brennan, Eoin P.;
McKay, Gareth J.;
Andrews, Darrell;
Doyle, Ross;
Looker, Helen C.;
Nelson, Robert G.

Publication type:

Article

Urinary metabolite profiling and risk of progression of diabetic nephropathy in 2670 individuals with type 1 diabetes.

Published in:

Diabetologia, 2022, v. 65, n. 1, p. 140, doi. 10.1007/s00125-021-05584-3

By:

Mutter, Stefan;
Valo, Erkka;
Aittomäki, Viljami;
Nybo, Kristian;
Raivonen, Lassi;
Thorn, Lena M.;
Forsblom, Carol;
Sandholm, Niina;
Würtz, Peter;
Groop, Per-Henrik

Publication type:

Article

Sphingomyelin and progression of renal and coronary heart disease in individuals with type 1 diabetes.

Published in:

Diabetologia, 2020, v. 63, n. 9, p. 1847, doi. 10.1007/s00125-020-05201-9

By:

Pongrac Barlovic, Drazenka;
Harjutsalo, Valma;
Sandholm, Niina;
Forsblom, Carol;
Groop, Per-Henrik

Publication type:

Article

Decreased plasma kallikrein activity is associated with reduced kidney function in individuals with type 1 diabetes.

Published in:

Diabetologia, 2020, v. 63, n. 7, p. 1349, doi. 10.1007/s00125-020-05144-1

By:

Härma, Mari-Anne;
Dahlström, Emma H.;
Sandholm, Niina;
Forsblom, Carol;
Groop, Per-Henrik;
Lehto, Markku

Publication type:

Article

Biomarker panels associated with progression of renal disease in type 1 diabetes.

Published in:

Diabetologia, 2019, v. 62, n. 9, p. 1616, doi. 10.1007/s00125-019-4915-0

By:

Colombo, Marco;
Valo, Erkka;
McGurnaghan, Stuart J.;
Sandholm, Niina;
Blackbourn, Luke A. K.;
Dalton, R. Neil;
Dunger, David;
Groop, Per-Henrik;
McKeigue, Paul M.;
Forsblom, Carol;
Colhoun, Helen M.

Publication type:

Article

Soluble receptor for AGE in diabetic nephropathy and its progression in Finnish individuals with type 1 diabetes.

Published in:

Diabetologia, 2019, v. 62, n. 7, p. 1268, doi. 10.1007/s00125-019-4883-4

By:

Wadén, Jenny M.;
Dahlström, Emma H.;
Elonen, Nina;
Thorn, Lena M.;
Wadén, Johan;
Sandholm, Niina;
Forsblom, Carol;
Groop, Per-Henrik

Publication type:

Article

A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria.

Published in:

Diabetologia, 2019, v. 62, n. 2, p. 292, doi. 10.1007/s00125-018-4783-z

By:

Ahluwalia, Tarunveer S.;
Schulz, Christina-Alexandra;
Waage, Johannes;
Skaaby, Tea;
Sandholm, Niina;
van Zuydam, Natalie;
Charmet, Romain;
Bork-Jensen, Jette;
Almgren, Peter;
Thuesen, Betina H.;
Bedin, Mathilda;
Brandslund, Ivan;
Christensen, Cramer K.;
Linneberg, Allan;
Ahlqvist, Emma;
Groop, Per-Henrik;
Hadjadj, Samy;
Tregouet, David-Alexandre;
Jørgensen, Marit E.;
Grarup, Niels

Publication type:

Article

SORBS1 gene, a new candidate for diabetic nephropathy: results from a multi-stage genome-wide association study in patients with type 1 diabetes.

Published in:

Diabetologia, 2015, v. 58, n. 3, p. 543, doi. 10.1007/s00125-014-3459-6

By:

Germain, Marine;
Pezzolesi, Marcus;
Sandholm, Niina;
McKnight, Amy;
Susztak, Katalin;
Lajer, Maria;
Forsblom, Carol;
Marre, Michel;
Parving, Hans-Henrik;
Rossing, Peter;
Toppila, Iiro;
Skupien, Jan;
Roussel, Ronan;
Ko, Yi-An;
Ledo, Nora;
Folkersen, Lasse;
Civelek, Mete;
Maxwell, Alexander;
Tregouet, David-Alexandre;
Groop, Per-Henrik

Publication type:

Article

Metabolomic Profile Predicts Development of Microalbuminuria in Individuals with Type 1 Diabetes.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-32085-y

By:

Haukka, Jani K.;
Sandholm, Niina;
Forsblom, Carol;
Cobb, Jeffrey E.;
Groop, Per-Henrik;
Ferrannini, Ele

Publication type:

Article

Confirmation of GLRA3 as a susceptibility locus for albuminuria in Finnish patients with type 1 diabetes.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-29211-1

By:

Sandholm, Niina;
Haukka, Jani K;
Toppila, Iiro;
Valo, Erkka;
Harjutsalo, Valma;
Forsblom, Carol;
Groop, Per-Henrik

Publication type:

Article

A Targeted Multiomics Approach to Identify Biomarkers Associated with Rapid eGFR Decline in Type 1 Diabetes.

Published in:

American Journal of Nephrology, 2020, v. 51, n. 10, p. 839, doi. 10.1159/000510830

By:

Limonte, Christine P.;
Valo, Erkka;
Montemayor, Daniel;
Afshinnia, Farsad;
Ahluwalia, Tarunveer S.;
Costacou, Tina;
Darshi, Manjula;
Forsblom, Carol;
Hoofnagle, Andrew N.;
Groop, Per-Henrik;
Miller, Rachel G.;
Orchard, Trevor J.;
Pennathur, Subramaniam;
Rossing, Peter;
Sandholm, Niina;
Snell-Bergeon, Janet K.;
Ye, Hongping;
Zhang, Jing;
Natarajan, Loki;
de Boer, Ian H.

Publication type:

Article

Progress in Defining the Genetic Basis of Diabetic Complications.

Published in:

2017

By:

Dahlström, Emma;
Sandholm, Niina;
Dahlström, Emma

Publication type:

journal article

Urinary metabolomics provide insights into coronary artery disease in individuals with type 1 diabetes.

Published in:

Cardiovascular Diabetology, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12933-024-02512-8

By:

Antikainen, Anni A.;
Mutter, Stefan;
Harjutsalo, Valma;
Thorn, Lena M.;
Groop, Per-Henrik;
Sandholm, Niina

Publication type:

Article

Variation in SLC19A3 and Protection From Microvascular Damage in Type 1 Diabetes.

Published in:

2016

By:

Porta, Massimo;
Toppila, Iiro;
Sandholm, Niina;
Hosseini, S. Mohsen;
Forsblom, Carol;
Hietala, Kustaa;
Borio, Lorenzo;
Harjutsalo, Valma;
Klein, Barbara E.;
Klein, Ronald;
Paterson, Andrew D.;
Groop, Per-Henrik;
DCCT/EDIC Research Group;
FinnDiane Study Group

Publication type:

journal article

Genetic Evidence for a Causal Role of Obesity in Diabetic Kidney Disease.

Published in:

2015

By:

Todd, Jennifer N.;
Dahlström, Emma H.;
Salem, Rany M.;
Sandholm, Niina;
Forsblom, Carol;
McKnight, Amy J.;
Maxwell, Alexander P.;
Brennan, Eoin;
Sadlier, Denise;
Godson, Catherine;
Groop, Per-Henrik;
Hirschhorn, Joel N.;
Florez, Jose C.;
FinnDiane Study Group

Publication type:

journal article

Association Testing of Previously Reported Variants in a Large Case-Control Meta-analysis of Diabetic Nephropathy.

Published in:

Diabetes, 2012, v. 61, n. 8, p. 2187, doi. 10.2337/db11-0751

By:

Williams, Winfred W.;
Salem, Rany M.;
Mcknight, Amy Jayne;
Sandholm, Niina;
Forsblom, Carol;
Taylor, Andrew;
Guiducci, Candace;
McAteer, Jarred B.;
McKay, Gareth J.;
Isakova, Tamara;
Brennan, Eoin P.;
Sadlier, Denise M.;
Palmer, Cameron;
Söderlund, Jenny;
Fagerholm, Emma;
Harjutsalo, Valma;
Lithovius, Raija;
Gordin, Daniel;
Hietala, Kustaa;
Kytö, Janne

Publication type:

Article

Genetic Examination of SETD7 and SUV39H1/H2 Methyltransferases and the Risk of Diabetes Complications in Patients With Type 1 Diabetes.

Published in:

Diabetes, 2011, v. 60, n. 11, p. 3073, doi. 10.2337/db11-0073

By:

Syreeni, Anna;
El-Osta, Assam;
Forsblom, Carol;
Sandholm, Niina;
Parkkonen, Maikki;
Tarnow, Lise;
Parving, Hans-Henrik;
McKnight, Amy J.;
Maxwell, Alexander P.;
Cooper, Mark E.;
Groop, Per-Henrik

Publication type:

Article

Novel genetic susceptibility loci for diabetic end-stage renal disease identified through robust naive Bayes classification.

Published in:

Diabetologia, 2014, v. 57, n. 8, p. 1611, doi. 10.1007/s00125-014-3256-2

By:

Sambo, Francesco;
Malovini, Alberto;
Sandholm, Niina;
Stavarachi, Monica;
Forsblom, Carol;
Mäkinen, Ville-Petteri;
Harjutsalo, Valma;
Lithovius, Raija;
Gordin, Daniel;
Parkkonen, Maija;
Saraheimo, Markku;
Thorn, Lena;
Tolonen, Nina;
Wadén, Johan;
He, Bing;
Österholm, Anne-May;
Tuomilehto, Jaako;
Lajer, Maria;
Salem, Rany;
McKnight, Amy

Publication type:

Article

Genome-wide association study of urinary albumin excretion rate in patients with type 1 diabetes.

Published in:

Diabetologia, 2014, v. 57, n. 6, p. 1143, doi. 10.1007/s00125-014-3202-3

By:

Sandholm, Niina;
Forsblom, Carol;
Mäkinen, Ville-Petteri;
McKnight, Amy;
Österholm, Anne-May;
He, Bing;
Harjutsalo, Valma;
Lithovius, Raija;
Gordin, Daniel;
Parkkonen, Maija;
Saraheimo, Markku;
Thorn, Lena;
Tolonen, Nina;
Wadén, Johan;
Tuomilehto, Jaakko;
Lajer, Maria;
Ahlqvist, Emma;
Möllsten, Anna;
Marcovecchio, M.;
Cooper, Jason

Publication type:

Article

Genetic factors affect the susceptibility to bacterial infections in diabetes.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88273-w

By:

Simonsen, Johan R.;
Käräjämäki, Annemari;
Antikainen, Anni A.;
Toppila, Iiro;
Ahlqvist, Emma;
Prasad, Rashmi;
Mansour-Aly, Dina;
Harjutsalo, Valma;
Järvinen, Asko;
Tuomi, Tiinamaija;
Groop, Leif;
Forsblom, Carol;
Groop, Per-Henrik;
Sandholm, Niina;
Lehto, Markku

Publication type:

Article

Body Mass Index and Mortality in Individuals With Type 1 Diabetes.

Published in:

2019

By:

Dahlström, Emma H;
Sandholm, Niina;
Forsblom, Carol M;
Thorn, Lena M;
Jansson, Fanny J;
Harjutsalo, Valma;
Groop, Per-Henrik;
FinnDiane Study Group

Publication type:

journal article

Dextran sodium sulfate‐induced colitis in male BALB/c mice leads to albuminuria and increased markers of inflammation and tissue damage in the kidney.

Published in:

Physiological Reports, 2025, v. 13, n. 5, p. 1, doi. 10.14814/phy2.70161

By:

Salmenkari, Hanne;
Adeshara, Krishna;
Pirttiniemi, Anniina;
Lindén, Jere;
Lehtonen, Sanna;
Sandholm, Niina;
Groop, Per‐Henrik;
Lehto, Markku

Publication type:

Article

Effect of serum sample storage temperature on metabolomic and proteomic biomarkers.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-08429-0

By:

Valo, Erkka;
Colombo, Marco;
Sandholm, Niina;
McGurnaghan, Stuart J.;
Blackbourn, Luke A. K.;
Dunger, David B.;
McKeigue, Paul M.;
Forsblom, Carol;
Groop, Per-Henrik;
Colhoun, Helen M.;
Turner, Charles;
Dalton, R. Neil

Publication type:

Article

Integrated analysis of blood DNA methylation, genetic variants, circulating proteins, microRNAs, and kidney failure in type 1 diabetes.

Published in:

Science Translational Medicine, 2024, v. 16, n. 748, p. 1, doi. 10.1126/scitranslmed.adj3385

By:

Chen, Zhuo;
Satake, Eiichiro;
Pezzolesi, Marcus G.;
Md Dom, Zaipul I.;
Stucki, Devorah;
Kobayashi, Hiroki;
Syreeni, Anna;
Johnson, Adam T.;
Wu, Xiwei;
Dahlström, Emma H.;
King, Jaxon B.;
Groop, Per-Henrik;
Rich, Stephen S.;
Sandholm, Niina;
Krolewski, Andrzej S.;
Natarajan, Rama

Publication type:

Article

Haptoglobin Genotype Does Not Confer a Risk of Stroke in Type 1 Diabetes.

Published in:

Diabetes, 2022, v. 71, n. 12, p. 2728, doi. 10.2337/db22-0327

By:

Syreeni, Anna;
Dahlström, Emma H.;
Hägg-Holmberg, Stefanie;
Forsblom, Carol;
Eriksson, Marika I.;
Harjutsalo, Valma;
Putaala, Jukka;
Groop, Per-Henrik;
Sandholm, Niina;
Thorn, Lena M.

Publication type:

Article

The Low-Expression Variant of Is Associated With Cardiovascular Disease in Type 1 Diabetes.

Published in:

2021

By:

Dahlström, Emma H.;
Saksi, Jani;
Forsblom, Carol;
Uglebjerg, Nicoline;
Mars, Nina;
Thorn, Lena M.;
Harjutsalo, Valma;
Rossing, Peter;
Ahluwalia, Tarunveer S.;
Lindsberg, Perttu J.;
Sandholm, Niina;
Groop, Per-Henrik;
FinnDiane Study Group

Publication type:

journal article

Novel Linkage Peaks Discovered for Diabetic Nephropathy in Individuals With Type 1 Diabetes.

Published in:

2021

By:

Haukka, Jani;
Sandholm, Niina;
Valo, Erkka;
Forsblom, Carol;
Harjutsalo, Valma;
Cole, Joanne B.;
McGurnaghan, Stuart J.;
Colhoun, Helen M.;
Groop, Per-Henrik;
FinnDiane Study Group

Publication type:

journal article

Is a Novel Susceptibility Gene for Diabetic Retinopathy in Type 1 Diabetes.

Published in:

2019

By:

Vuori, Nadja;
Sandholm, Niina;
Kumar, Anmol;
Hietala, Kustaa;
Syreeni, Anna;
Forsblom, Carol;
Juuti-Uusitalo, Kati;
Skottman, Heli;
Minako Imamura;
Shiro Maeda;
Summanen, Paula A.;
Lehto, Markku;
Groop, Per-Henrik;
Minako Imamura;
Imamura, Minako;
Maeda, Shiro;
FinnDiane Study

Publication type:

journal article

Genetic Determinants of Glycated Hemoglobin in Type 1 Diabetes.

Published in:

2019

By:

Syreeni, Anna;
Sandholm, Niina;
Jingjing Cao;
Toppila, Iiro;
Maahs, David M.;
Rewers, Marian J.;
Snell-Bergeon, Janet K.;
Costacou, Tina;
Orchard, Trevor J.;
Caramori, M. Luiza;
Mauer, Michael;
Klein, Barbara E. K.;
Klein, Ronald;
Valo, Erkka;
Parkkonen, Maija;
Forsblom, Carol;
Harjutsalo, Valma;
Paterson, Andrew D.;
Groop, Per-Henrik;
Cao, Jingjing

Publication type:

journal article