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Telomere Targeting Approaches in Cancer: Beyond Length Maintenance.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 3784, doi. 10.3390/ijms23073784
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- Publication type:
- Article
Targeting of Telomeric Repeat-Containing RNA G-Quadruplexes: From Screening to Biophysical and Biological Characterization of a New Hit Compound.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10315, doi. 10.3390/ijms221910315
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- Publication type:
- Article
Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect.
- Published in:
- 2007
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- Publication type:
- journal article
Editorial: Novel insights connecting telomere biology to cancer development and progression.
- Published in:
- Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1405618
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- Publication type:
- Article
Editorial: RNA recognition landscapes and anticancer drug targeting.
- Published in:
- Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1222883
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- Publication type:
- Article
SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.
- Published in:
- Nucleic Acids Research, 2017, v. 45, n. 4, p. 1820, doi. 10.1093/nar/gkw1202
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- Publication type:
- Article
Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance.
- Published in:
- Nucleic Acids Research, 2016, v. 44, n. 4, p. 1579, doi. 10.1093/nar/gkv1122
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- Publication type:
- Article
A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.
- Published in:
- Nucleic Acids Research, 2015, v. 43, n. 3, p. 1759, doi. 10.1093/nar/gkv006
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- Publication type:
- Article
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. 5, p. 2945, doi. 10.1093/nar/gkt1289
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- Publication type:
- Article
Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway.
- Published in:
- Nucleic Acids Research, 2009, v. 37, n. 16, p. 5353, doi. 10.1093/nar/gkp582
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- Publication type:
- Article
TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells.
- Published in:
- Nature Cell Biology, 2013, v. 15, n. 7, p. 818, doi. 10.1038/ncb2774
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- Publication type:
- Article
Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2014, v. 33, n. 1, p. 1, doi. 10.1186/s13046-014-0081-x
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- Publication type:
- Article
On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2013, v. 32, n. 1, p. 1, doi. 10.1186/1756-9966-32-68
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- Publication type:
- Article
Dyads of G‐Quadruplex Ligands Triggering DNA Damage Response and Tumour Cell Growth Inhibition at Subnanomolar Concentration.
- Published in:
- Chemistry - A European Journal, 2019, v. 25, n. 47, p. 11085, doi. 10.1002/chem.201900766
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- Publication type:
- Article
Diagnosis and treatment of ALT tumors: is Trabectedin a new therapeutic option?
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2017, v. 36, p. 1, doi. 10.1186/s13046-017-0657-3
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- Publication type:
- Article
The β-arrestin1/endothelin axis bolsters ovarian fibroblast-dependent invadosome activity and cancer cell metastatic potential.
- Published in:
- Cell Death & Disease, 2024, v. 15, n. 5, p. 1, doi. 10.1038/s41419-024-06730-6
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- Publication type:
- Article
Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells.
- Published in:
- Cell Death & Disease, 2018, v. 9, n. 10, p. 1, doi. 10.1038/s41419-018-1065-0
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- Publication type:
- Article
TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment.
- Published in:
- Nucleic Acids Research, 2019, v. 47, n. 7, p. 3365, doi. 10.1093/nar/gkz041
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- Publication type:
- Article
Fibroblast-Induced Paradoxical PI3K Pathway Activation in PTEN-Competent Colorectal Cancer: Implications for Therapeutic PI3K/mTOR Inhibition.
- Published in:
- Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.862806
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- Publication type:
- Article
G-quadruplex Stabilization Fuels the ALT Pathway in ALT-positive Osteosarcoma Cells.
- Published in:
- Genes, 2020, v. 11, n. 3, p. 304, doi. 10.3390/genes11030304
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- Publication type:
- Article
BRCA2 Deletion Induces Alternative Lengthening of Telomeres in Telomerase Positive Colon Cancer Cells.
- Published in:
- Genes, 2019, v. 10, n. 9, p. 697, doi. 10.3390/genes10090697
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- Publication type:
- Article
Aromatic Core Extension in the Series of N-Cyclic Bay-Substituted Perylene G-Quadruplex Ligands: Increased Telomere Damage, Antitumor Activity, and Strong Selectivity for Neoplastic over Healthy Cells.
- Published in:
- ChemMedChem, 2012, v. 7, n. 12, p. 2144, doi. 10.1002/cmdc.201200348
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- Publication type:
- Article
Drug repositioning strategy for the identification of novel telomere‐damaging agents: A role for NAMPT inhibitors.
- Published in:
- Aging Cell, 2023, v. 22, n. 11, p. 1, doi. 10.1111/acel.13944
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- Publication type:
- Article