Works matching AU Salmena, Leonardo

Results: 26

Prediction and Analysis of SARS-CoV-2-Targeting MicroRNA in Human Lung Epithelium.

Published in:

Genes, 2020, v. 11, n. 9, p. 1002, doi. 10.3390/genes11091002

By:

Chow, Jonathan Tak-Sum;
Salmena, Leonardo

Publication type:

Article

SubID, a non-median dichotomization tool for heterogeneous populations, reveals the pan-cancer significance of INPP4B and its regulation by EVI1 in AML.

Published in:

PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0191510

By:

Dzneladze, Irakli;
Woolley, John F.;
Rossell, Carla;
Han, Youqi;
Rashid, Ayesha;
Jain, Michael;
Reimand, Jüri;
Minden, Mark D.;
Salmena, Leonardo

Publication type:

Article

A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer.

Published in:

Nature Genetics, 2013, v. 45, n. 7, p. 747, doi. 10.1038/ng.2650

By:

Lunardi, Andrea;
Ala, Ugo;
Epping, Mirjam T;
Salmena, Leonardo;
Clohessy, John G;
Webster, Kaitlyn A;
Wang, Guocan;
Mazzucchelli, Roberta;
Bianconi, Maristella;
Stack, Edward C;
Lis, Rosina;
Patnaik, Akash;
Cantley, Lewis C;
Bubley, Glenn;
Cordon-Cardo, Carlos;
Gerald, William L;
Montironi, Rodolfo;
Signoretti, Sabina;
Loda, Massimo;
Nardella, Caterina

Publication type:

Article

Subtle variations in Pten dose determine cancer susceptibility.

Published in:

Nature Genetics, 2010, v. 42, n. 5, p. 454, doi. 10.1038/ng.556

By:

Alimonti, Andrea;
Carracedo, Arkaitz;
Clohessy, John G.;
Trotman, Lloyd C.;
Nardella, Caterina;
Egia, Ainara;
Salmena, Leonardo;
Sampieri, Katia;
Haveman, William J.;
Brogi, Edi;
Richardson, Andrea L.;
Jiangwen Zhang;
Pandolfi, Pier Paolo

Publication type:

Article

Caspase-8 inactivation in T cells increases necroptosis and suppresses autoimmunity in Bim<sup>-/-</sup> mice.

Published in:

Journal of Cell Biology, 2011, v. 195, n. 2, p. 277, doi. 10.1083/jcb.201103053

By:

Bohgaki, Toshiyuki;
Mozo, Julien;
Salmena, Leonardo;
Matysiak-Zablocki, Elzbieta;
Bohgaki, Miyuki;
Sanchez, Otto;
Strasser, Andreas;
Hakem, Anne;
Hakem, Razqallah

Publication type:

Article

microRNAs and Acute Myeloid Leukemia Chemoresistance: A Mechanistic Overview.

Published in:

Frontiers in Oncology, 2017, p. 1, doi. 10.3389/fonc.2017.00255

By:

Gabra, Martino Marco;
Salmena, Leonardo

Publication type:

Article

Neuronal Deletion of Caspase 8 Protects against Brain Injury in Mouse Models of Controlled Cortical Impact and Kainic Acid-Induced Excitotoxicity.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024341

By:

Krajewska, Maryla;
You, Zerong;
Rong, Juan;
Kress, Christina;
Huang, Xianshu;
Yang, Jinsheng;
Kyoda, Tiffany;
Leyva, Ricardo;
Banares, Steven;
Yue Hu;
Chia-Hung Sze;
Whalen, Michael J.;
Salmena, Leonardo;
Hakem, Razqallah;
Head, Brian P.;
Reed, John C.;
Krajewski, Stan

Publication type:

Article

Identification of the miR-106b~25 MicroRNA Cluster as a Proto-Oncogenic PTEN-Targeting Intron That Cooperates with Its Host Gene MCM7 in Transformation.

Published in:

Science Signaling, 2010, v. 3, n. 123, p. 1, doi. 10.1126/scisignal.2000594

By:

Poliseno, Laura;
Salmena, Leonardo;
Riccardi, Luisa;
Fornari, Alessandro;
Song, Min Sup;
Hobbs, Robin M.;
Sportoletti, Paolo;
Varmeh, Shorheh;
Egia, Ainara;
Fedele, Giuseppe;
Rameh, Lucia;
Loda, Massimo;
Pandolfi, Pier Paolo

Publication type:

Article

Identification of the miR-106b~25 MicroRNA Cluster as a Proto-Oncogenic PTEN-Targeting Intron That Cooperates with Its Host Gene MCM7 in Transformation.

Published in:

Science Signaling, 2010, v. 3, n. 117, p. 1, doi. 10.1126/scisignal.2000594

By:

Poliseno, Laura;
Salmena, Leonardo;
Riccardi, Luisa;
Fornari, Alessandro;
Song, Min Sup;
Hobbs, Robin M.;
Sportoletti, Paolo;
Varmeh, Shorheh;
Egia, Ainara;
Fedele, Giuseppe;
Rameh, Lucia;
Loda, Massimo;
Pandolfi, Pier Paolo

Publication type:

Article

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.

Published in:

2008

By:

Carracedo, Arkaitz;
Li Ma;
Teruya-Feldstein, Julie;
Rojo, Federico;
Salmena, Leonardo;
Alimonti, Andrea;
Egia, Ainara;
Sasaki, Atsuo T.;
Thomas, George;
Kozma, Sara C.;
Papa, Antonella;
Nardella, Caterina;
Cantley, Lewis C.;
Baselga, Jose;
Pandolfi, Pier Paolo;
Ma, Li

Publication type:

journal article

From photomorphogenesis to cancer: A CSN journey.

Published in:

Cell Cycle, 2013, v. 12, n. 2, p. 205, doi. 10.4161/cc.23422

By:

Salmena, Leonardo;
Hakem, Razqallah

Publication type:

Article

INPP4B promotes PDAC aggressiveness via PIKfyve and TRPML-1-mediated lysosomal exocytosis.

Published in:

Journal of Cell Biology, 2024, v. 223, n. 11, p. 1, doi. 10.1083/jcb.202401012

By:

Saffi, Golam T.;
To, Lydia;
Kleine, Nicholas;
Melo, Ché M. P.;
Keyue Chen;
Genc, Gizem;
Lee, K. C. Daniel;
Tak-Sum Chow, Jonathan;
Gun Ho Jang;
Gallinger, Steven;
Botelho, Roberto J.;
Salmena, Leonardo

Publication type:

Article

Changing venues for tumour suppression: balancing destruction and localization by monoubiquitylation.

Published in:

2007

By:

Salmena, Leonardo;
Pandolfi, Pier Paolo

Publication type:

research

Increased Serum Mir-150-3p Expression Is Associated with Radiological Lung Injury Improvement in Patients with COVID-19.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 7, p. N.PAG, doi. 10.3390/v14071363

By:

Bueno, Larissa C. M.;
Paim, Layde R.;
Minin, Eduarda O. Z.;
da Silva, Luís Miguel;
Mendes, Paulo R.;
Kiyota, Tatiana A.;
Schreiber, Angelica Z.;
Bombassaro, Bruna;
Mansour, Eli;
Moretti, Maria Luiza;
Chow, Jonathan Tak-Sum;
Salmena, Leonardo;
Coelho-Filho, Otavio R.;
Velloso, Licio A.;
Nadruz, Wilson;
Schreiber, Roberto

Publication type:

Article

Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.

Published in:

2012

By:

Kotsopoulos, Joanne;
Lubinski, Jan;
Salmena, Leonardo;
Lynch, Henry T;
Kim-Sing, Charmaine;
Foulkes, William D;
Ghadirian, Parviz;
Neuhausen, Susan L;
Demsky, Rochelle;
Tung, Nadine;
Ainsworth, Peter;
Senter, Leigha;
Eisen, Andrea;
Eng, Charis;
Singer, Christian;
Ginsburg, Ophira;
Blum, Joanne;
Huzarski, Tomasz;
Poll, Aletta;
Sun, Ping

Publication type:

journal article

Serum osteoprotegerin levels and mammographic density among high-risk women.

Published in:

2018

By:

Moran, Olivia;
Zaman, Tasnim;
Eisen, Andrea;
Demsky, Rochelle;
Blackmore, Kristina;
Knight, Julia A.;
Elser, Christine;
Ginsburg, Ophira;
Zbuk, Kevin;
Yaffe, Martin;
Narod, Steven A.;
Salmena, Leonardo;
Kotsopoulos, Joanne

Publication type:

journal article

The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network.

Published in:

Nature, 2008, v. 455, n. 7214, p. 813, doi. 10.1038/nature07290

By:

Min Sup Song;
Salmena, Leonardo;
Carracedo, Arkaitz;
Egia, Ainara;
Lo-Coco, Francesco;
Teruya-Feldstein, Julie;
Pandolfi, Pier Paolo

Publication type:

Article

The functions and regulation of the PTEN tumour suppressor.

Published in:

Nature Reviews Molecular Cell Biology, 2012, v. 13, n. 5, p. 283, doi. 10.1038/nrm3330

By:

Song, Min Sup;
Salmena, Leonardo;
Pandolfi, Pier Paolo

Publication type:

Article

Reduced BRCA1 transcript levels in freshly isolated blood leukocytes from BRCA1 mutation carriers is mutation specific.

Published in:

2016

By:

Chehade, Rania;
Pettapiece-Phillips, Rachael;
Salmena, Leonardo;
Kotlyar, Max;
Jurisica, Igor;
Narod, Steven A.;
Akbari, Mohammad R.;
Kotsopoulos, Joanne

Publication type:

journal article

Distinct In Vivo Roles of Caspase-8 in β-Cells in Physiological and Diabetes Models.

Published in:

Diabetes, 2007, v. 56, n. 9, p. 2302, doi. 10.2337/db06-1771

By:

Liadis, Nicole;
Salmena, Leonardo;
Kwan, Edwin;
Tajmir, Panteha;
Schroer, Stephanie A.;
Radziszewska, Anna;
Li, Xie;
Sheu, Laura;
Eweida, Mohamed;
Xu, Shilong;
Gaisano, Herbert Y.;
Hakem, Razqallah;
Woo, Minna

Publication type:

Article

PTENP1 is a ceRNA for PTEN: it's CRISPR clear.

Published in:

Journal of Hematology & Oncology, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s13045-020-00894-2

By:

Vitiello, Marianna;
Evangelista, Monica;
Zhang, Yang;
Salmena, Leonardo;
Pandolfi, Pier Paolo;
Poliseno, Laura

Publication type:

Article

Reactive oxygen species prevent lysosome coalescence during PIKfyve inhibition.

Published in:

PLoS ONE, 2021, v. 16, n. 11, p. 1, doi. 10.1371/journal.pone.0259313

By:

Saffi, Golam T.;
Tang, Evan;
Mamand, Sami;
Inpanathan, Subothan;
Fountain, Aaron;
Salmena, Leonardo;
Botelho, Roberto J.

Publication type:

Article

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology.

Published in:

Nature, 2010, v. 465, n. 7301, p. 1033, doi. 10.1038/nature09144

By:

Poliseno, Laura;
Salmena, Leonardo;
Zhang, Jiangwen;
Carver, Brett;
Haveman, William J.;
Pandolfi, Pier Paolo

Publication type:

Article

Stroma-derived miR-214 coordinates tumor dissemination.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2023, v. 42, p. 1, doi. 10.1186/s13046-022-02553-5

By:

Orso, Francesca;
Virga, Federico;
Dettori, Daniela;
Dalmasso, Alberto;
Paradzik, Mladen;
Savino, Aurora;
Pomatto, Margherita A. C.;
Quirico, Lorena;
Cucinelli, Stefania;
Coco, Martina;
Mareschi, Katia;
Fagioli, Franca;
Salmena, Leonardo;
Camussi, Giovanni;
Provero, Paolo;
Poli, Valeria;
Mazzone, Massimiliano;
Pandolfi, Pier Paolo;
Taverna, Daniela

Publication type:

Article

Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity.

Published in:

EMBO Journal, 2004, v. 23, n. 18, p. 3677, doi. 10.1038/sj.emboj.7600371

By:

McPherson, John Peter;
Tamblyn, Laura;
Elia, Andrew;
Migon, Eva;
Shehabeldin, Amro;
Matysiak-Zablocki, Elzbieta;
Lemmers, Bénédicte;
Salmena, Leonardo;
Hakem, Anne;
Fish, Jason;
Kassam, Farah;
Squire, Jeremy;
Bruneau, Benoit G.;
Hande, M. Prakash;
Hakem, Razqallah

Publication type:

Article

Role of Pirh2 in Mediating the Regulation of p53 and c-Myc.

Published in:

PLoS Genetics, 2011, v. 7, n. 11, p. 1, doi. 10.1371/journal.pgen.1002360

By:

Hakem, Anne;
Bohgaki, Miyuki;
Lemmers, Bénédicte;
Tai, Elisabeth;
Salmena, Leonardo;
Matysiak-Zablocki, Elzbieta;
Yong-Sam Jung;
Karaskova, Jana;
Kaustov, Lilia;
Duan, Shili;
Madore, Jason;
Boutros, Paul;
Yi Sheng;
Chesi, Marta;
Bergsagel, P. Leif;
Perez-Ordonez, Bayardo;
Mes-Masson, Anne-Marie;
Penn, Linda;
Squire, Jeremy;
Xinbin Chen

Publication type:

Article