Works by Salerno, Loredana

Results: 37

Synthesis and Experimental Validation of New Designed Heterocyclic Compounds with Antiproliferative Activity versus Breast Cancer Cell Lines MCF-7 and MDA-MB-231.

Published in:

Journal of Chemistry, 2017, p. 1, doi. 10.1155/2017/9729284

By:

Barresi, Vincenza;
Bonaccorso, Carmela;
Cristaldi, Domenico A.;
Modica, Maria N.;
Musso, Nicolò;
Pittalà, Valeria;
Salerno, Loredana;
Fortuna, Cosimo G.

Publication type:

Article

Synthesis and biological activity of 1-, 2- or 3-Substituted benzothieno-[2,3- d]triazole derivatives structurally related to trazodone.

Published in:

Journal of Heterocyclic Chemistry, 1999, v. 36, n. 2, p. 549, doi. 10.1002/jhet.5570360235

By:

Guerrera, Francesco;
Salerno, Loredana;
Sarvà, Maria Concetta;
Siracusa, Maria Angela;
Corsaro, Antonino;
Pistarà, Venerando;
Capasso, Raffaele;
Raso, Giuseppina Mattace

Publication type:

Article

Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia.

Published in:

Molecules, 2022, v. 27, n. 10, p. 3220, doi. 10.3390/molecules27103220

By:

Ciaffaglione, Valeria;
Consoli, Valeria;
Intagliata, Sebastiano;
Marrazzo, Agostino;
Romeo, Giuseppe;
Pittalà, Valeria;
Greish, Khaled;
Vanella, Luca;
Floresta, Giuseppe;
Rescifina, Antonio;
Salerno, Loredana;
Sorrenti, Valeria

Publication type:

Article

Combination of Heme Oxygenase-1 Inhibition and Sigma Receptor Modulation for Anticancer Activity.

Published in:

Molecules, 2021, v. 26, n. 13, p. 3860, doi. 10.3390/molecules26133860

By:

Romeo, Giuseppe;
Ciaffaglione, Valeria;
Amata, Emanuele;
Dichiara, Maria;
Calabrese, Loredana;
Vanella, Luca;
Sorrenti, Valeria;
Grosso, Salvo;
D'Amico, Agata Grazia;
D'Agata, Velia;
Intagliata, Sebastiano;
Salerno, Loredana

Publication type:

Article

Design, Synthesis, and Antitumor Activity of Olmutinib Derivatives Containing Acrylamide Moiety.

Published in:

Molecules, 2021, v. 26, n. 10, p. 3041, doi. 10.3390/molecules26103041

By:

Hu, Xiaohan;
Tang, Sheng;
Yang, Feiyi;
Zheng, Pengwu;
Xu, Shan;
Pan, Qingshan;
Zhu, Wufu;
Salerno, Loredana;
Intagliata, Sebastiano

Publication type:

Article

Hybrid Drugs—A Strategy for Overcoming Anticancer Drug Resistance?

Published in:

Molecules, 2021, v. 26, n. 9, p. 2601, doi. 10.3390/molecules26092601

By:

Szumilak, Marta;
Wiktorowska-Owczarek, Anna;
Stanczak, Andrzej;
Salerno, Loredana

Publication type:

Article

Photocytotoxic Activity of Ruthenium(II) Complexes with Phenanthroline-Hydrazone Ligands.

Published in:

Molecules, 2021, v. 26, n. 7, p. 2084, doi. 10.3390/molecules26072084

By:

Silva-Caldeira, Priscila Pereira;
Oliveira Junior, Antônio Carlos Almendagna de;
Pereira-Maia, Elene Cristina;
Salerno, Loredana;
Intagliata, Sebastiano

Publication type:

Article

Synthesis and Evaluation of Thymol-Based Synthetic Derivatives as Dual-Action Inhibitors against Different Strains of H. pylori and AGS Cell Line.

Published in:

Molecules, 2021, v. 26, n. 7, p. 1829, doi. 10.3390/molecules26071829

By:

Sisto, Francesca;
Carradori, Simone;
Guglielmi, Paolo;
Spano, Mattia;
Secci, Daniela;
Granese, Arianna;
Sobolev, Anatoly P.;
Grande, Rossella;
Campestre, Cristina;
Di Marcantonio, Maria Carmela;
Mincione, Gabriella;
Salerno, Loredana

Publication type:

Article

Dual 2-Hydroxypropyl-β-Cyclodextrin and 5,10,15,20-Tetrakis (4-Hydroxyphenyl) Porphyrin System as a Novel Chiral-Achiral Selector Complex for Enantioseparation of Aminoalkanol Derivatives with Anticancer Activity in Capillary Electrophoresis.

Published in:

Molecules, 2021, v. 26, n. 4, p. 993, doi. 10.3390/molecules26040993

By:

Grodner, Błażej;
Napiórkowska, Mariola;
Salerno, Loredana

Publication type:

Article

In-Vitro and In-Silico Evaluations of Heterocyclic-Containing Diarylpentanoids as Bcl-2 Inhibitors Against LoVo Colorectal Cancer Cells.

Published in:

Molecules, 2020, v. 25, n. 17, p. 3877, doi. 10.3390/molecules25173877

By:

Leong, Sze Wei;
Chia, Suet Lin;
Abas, Faridah;
Yusoff, Khatijah;
Antonello, Mai;
Salerno, Loredana

Publication type:

Article

Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands.

Published in:

Molecules, 2020, v. 25, n. 8, p. 1851, doi. 10.3390/molecules25081851

By:

Intagliata, Sebastiano;
Helal, Mohamed A.;
Materia, Luisa;
Pittalà, Valeria;
Salerno, Loredana;
Marrazzo, Agostino;
Cagnotto, Alfredo;
Salmona, Mario;
Modica, Maria N.;
Romeo, Giuseppe

Publication type:

Article

Novel Structural Insight into Inhibitors of Heme Oxygenase-1 (HO-1) by New Imidazole-Based Compounds: Biochemical and In Vitro Anticancer Activity Evaluation.

Published in:

Molecules, 2018, v. 23, n. 5, p. 1209, doi. 10.3390/molecules23051209

By:

Greish, Khaled F.;
Salerno, Loredana;
Al Zahrani, Reem;
Amata, Emanuele;
Modica, Maria N.;
Romeo, Giuseppe;
Marrazzo, Agostino;
Prezzavento, Orazio;
Sorrenti, Valeria;
Rescifina, Antonio;
Floresta, Giuseppe;
Intagliata, Sebastiano;
Pittalà, Valeria

Publication type:

Article

In Vitro Antioxidant Activity of Idebenone Derivative-Loaded Solid Lipid Nanoparticles.

Published in:

Molecules, 2017, v. 22, n. 6, p. 887, doi. 10.3390/molecules22060887

By:

Montenegro, Lucia;
Modica, Maria N.;
Salerno, Loredana;
Panico, Anna Maria;
Crascì, Lucia;
Puglisi, Giovanni;
Romeo, Giuseppe

Publication type:

Article

A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis.

Published in:

Journal of Computer-Aided Molecular Design, 2021, v. 35, n. 3, p. 297, doi. 10.1007/s10822-021-00374-w

By:

Ben Khalaf, Noureddine;
Pham, Susie;
Romeo, Giuseppe;
Abdelghany, Sara;
Intagliata, Sebastiano;
Sedillo, Peter;
Salerno, Loredana;
Gonzales, Jessica;
Fathallah, Dahmani M.;
Perkins, Douglas J.;
Hurwitz, Ivy;
Pittalà, Valeria

Publication type:

Article

In vitro and in silico analysis of imatinib analogues as anti- Trypanosoma cruzi drug candidates.

Published in:

Parasitology, 2023, v. 150, n. 4, p. 359, doi. 10.1017/S0031182023000057

By:

Nesic de Freitas, Luca S. F.;
da Silva, Cristiane França;
Intagliata, Sebastiano;
Amata, Emanuele;
Salerno, Loredana;
Soeiro, Maria de Nazaré Correia

Publication type:

Article

Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5‐Fluorouracil and Imidazole‐Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells.

Published in:

ChemMedChem, 2023, v. 18, n. 8, p. 1, doi. 10.1002/cmdc.202300047

By:

Salerno, Loredana;
Sorrenti, Valeria;
Pittalà, Valeria;
Consoli, Valeria;
Modica, Maria N.;
Romeo, Giuseppe;
Marrazzo, Agostino;
Giuliano, Michela;
Zajdel, Paweł;
Vanella, Luca;
Intagliata, Sebastiano

Publication type:

Article

Mutual Prodrugs of 5‐Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs.

Published in:

ChemMedChem, 2021, v. 16, n. 23, p. 3496, doi. 10.1002/cmdc.202100473

By:

Ciaffaglione, Valeria;
Modica, Maria N.;
Pittalà, Valeria;
Romeo, Giuseppe;
Salerno, Loredana;
Intagliata, Sebastiano

Publication type:

Article

Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D‐QSAR Coupled to Scaffold‐Hopping Analysis.

Published in:

ChemMedChem, 2018, v. 13, n. 13, p. 1336, doi. 10.1002/cmdc.201800176

By:

Floresta, Giuseppe;
Amata, Emanuele;
Dichiara, Maria;
Marrazzo, Agostino;
Salerno, Loredana;
Romeo, Giuseppe;
Prezzavento, Orazio;
Pittalà, Valeria;
Rescifina, Antonio

Publication type:

Article

Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors.

Published in:

ChemMedChem, 2017, v. 12, n. 22, p. 1873, doi. 10.1002/cmdc.201700321

By:

Amata, Emanuele;
Marrazzo, Agostino;
Dichiara, Maria;
Modica, Maria N.;
Salerno, Loredana;
Prezzavento, Orazio;
Nastasi, Giovanni;
Rescifina, Antonio;
Romeo, Giuseppe;
Pittalà, Valeria

Publication type:

Article

Evaluation of Imidazole-Based Compounds as Heme Oxygenase-1 Inhibitors.

Published in:

Chemical Biology & Drug Design, 2012, v. 80, n. 6, p. 876, doi. 10.1111/cbdd.12015

By:

Sorrenti, Valeria;
Guccione, Salvatore;
Di Giacomo, Claudia;
Modica, Maria N.;
Pittalà, Valeria;
Acquaviva, Rosaria;
Basile, Livia;
Pappalardo, Morena;
Salerno, Loredana

Publication type:

Article

Non-competitive heme oxygenase-1 activity inhibitor reduces non-small cell lung cancer glutathione content and regulates cell proliferation.

Published in:

Molecular Biology Reports, 2020, v. 47, n. 3, p. 1949, doi. 10.1007/s11033-020-05292-y

By:

Spampinato, Mariarita;
Sferrazzo, Giuseppe;
Pittalà, Valeria;
Di Rosa, Michelino;
Vanella, Luca;
Salerno, Loredana;
Sorrenti, Valeria;
Carota, Giuseppe;
Parrinello, Nunziatina;
Raffaele, Marco;
Tibullo, Daniele;
Li Volti, Giovanni;
Barbagallo, Ignazio

Publication type:

Article

The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated.

Published in:

Antioxidants, 2023, v. 12, n. 10, p. 1859, doi. 10.3390/antiox12101859

By:

Suárez-Rojas, Irene;
Pérez-Fernández, Montse;
Bai, Xue;
Martínez-Martel, Ignacio;
Intagliata, Sebastiano;
Pittalà, Valeria;
Salerno, Loredana;
Pol, Olga

Publication type:

Article

Novel Heme Oxygenase-1 Inducers Palliate Inflammatory Pain and Emotional Disorders by Regulating NLRP3 Inflammasome and Activating the Antioxidant Pathway.

Published in:

Antioxidants, 2023, v. 12, n. 10, p. 1794, doi. 10.3390/antiox12101794

By:

Pérez-Fernández, Montse;
Suárez-Rojas, Irene;
Bai, Xue;
Martínez-Martel, Ignacio;
Ciaffaglione, Valeria;
Pittalà, Valeria;
Salerno, Loredana;
Pol, Olga

Publication type:

Article

Fourfold Filtered Statistical/Computational Approach for the Identification of Imidazole Compounds as HO-1 Inhibitors from Natural Products.

Published in:

Marine Drugs, 2019, v. 17, n. 2, p. 113, doi. 10.3390/md17020113

By:

Floresta, Giuseppe;
Amata, Emanuele;
Gentile, Davide;
Romeo, Giuseppe;
Marrazzo, Agostino;
Pittalà, Valeria;
Salerno, Loredana;
Rescifina, Antonio

Publication type:

Article

Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts.

Published in:

Scientific World Journal, 2014, p. 1, doi. 10.1155/2014/719486

By:

Salerno, Loredana;
Modica, Maria N.;
Pittalà, Valeria;
Romeo, Giuseppe;
Siracusa, Maria A.;
Di Giacomo, Claudia;
Sorrenti, Valeria;
Acquaviva, Rosaria

Publication type:

Article

Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries.

Published in:

Clinical Science, 2017, v. 131, n. 14, p. 1701, doi. 10.1042/CS20170157

By:

Amata, Emanuele;
Pittalà, Valeria;
Marrazzo, Agostino;
Parenti, Carmela;
Prezzavento, Orazio;
Arena, Emanuela;
Nabavi, Seyed Mohammad;
Salerno, Loredana

Publication type:

Article

Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 10, p. 5709, doi. 10.3390/ijms23105709

By:

Consoli, Valeria;
Sorrenti, Valeria;
Pittalà, Valeria;
Greish, Khaled;
D'Amico, Agata Grazia;
Romeo, Giuseppe;
Intagliata, Sebastiano;
Salerno, Loredana;
Vanella, Luca

Publication type:

Article

Novel Heme Oxygenase-1 (HO-1) Inducers Based on Dimethyl Fumarate Structure.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 24, p. 9541, doi. 10.3390/ijms21249541

By:

Sorrenti, Valeria;
Vanella, Luca;
Platania, Chiara Bianca Maria;
Greish, Khaled;
Bucolo, Claudio;
Pittalà, Valeria;
Salerno, Loredana

Publication type:

Article

New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 6, p. 1923, doi. 10.3390/ijms21061923

By:

Ciaffaglione, Valeria;
Intagliata, Sebastiano;
Pittalà, Valeria;
Marrazzo, Agostino;
Sorrenti, Valeria;
Vanella, Luca;
Rescifina, Antonio;
Floresta, Giuseppe;
Sultan, Ameera;
Greish, Khaled;
Salerno, Loredana

Publication type:

Article

Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 10, p. 2593, doi. 10.3390/ijms20102593

By:

Raffaele, Marco;
Pittalà, Valeria;
Zingales, Veronica;
Barbagallo, Ignazio;
Salerno, Loredana;
Li Volti, Giovanni;
Romeo, Giuseppe;
Carota, Giuseppe;
Sorrenti, Valeria;
Vanella, Luca

Publication type:

Article

Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 10, p. 2441, doi. 10.3390/ijms20102441

By:

Sorrenti, Valeria;
Raffaele, Marco;
Vanella, Luca;
Acquaviva, Rosaria;
Salerno, Loredana;
Pittalà, Valeria;
Intagliata, Sebastiano;
Di Giacomo, Claudia

Publication type:

Article

Glucose-Impaired Corneal Re-Epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate.

Published in:

Antioxidants, 2021, v. 10, n. 6, p. 831, doi. 10.3390/antiox10060831

By:

Giurdanella, Giovanni;
Longo, Anna;
Salerno, Loredana;
Romeo, Giuseppe;
Intagliata, Sebastiano;
Lupo, Gabriella;
Distefano, Alfio;
Platania, Chiara Bianca Maria;
Bucolo, Claudio;
Li Volti, Giovanni;
Anfuso, Carmelina Daniela;
Pittalà, Valeria

Publication type:

Article

Heme Oxygenase Inhibition Sensitizes Neuroblastoma Cells to Carfilzomib.

Published in:

Molecular Neurobiology, 2019, v. 56, n. 2, p. 1451, doi. 10.1007/s12035-018-1133-6

By:

Barbagallo, Ignazio;
Giallongo, Cesarina;
Volti, Giovanni Li;
Distefano, Alfio;
Camiolo, Giuseppina;
Raffaele, Marco;
Salerno, Loredana;
Pittalà, Valeria;
Sorrenti, Valeria;
Avola, Roberto;
Di Rosa, Michelino;
Vanella, Luca;
Di Raimondo, Francesco;
Tibullo, Daniele

Publication type:

Article

Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells.

Published in:

Oxidative Medicine & Cellular Longevity, 2017, p. 1, doi. 10.1155/2017/1420892

By:

Pittalà, Valeria;
Fidilio, Annamaria;
Lazzara, Francesca;
Platania, Chiara Bianca Maria;
Salerno, Loredana;
Foresti, Roberta;
Drago, Filippo;
Bucolo, Claudio

Publication type:

Article

Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2024, v. 39, n. 1, p. 1, doi. 10.1080/14756366.2024.2337191

By:

Salerno, Loredana;
Notaro, Antonietta;
Consoli, Valeria;
Affranchi, Federica;
Pittalà, Valeria;
Sorrenti, Valeria;
Vanella, Luca;
Giuliano, Michela;
Intagliata, Sebastiano

Publication type:

Article

Novel mutual prodrug of 5-fluorouracil and heme oxygenase-1 inhibitor (5-FU/HO-1 hybrid): design and preliminary in vitro evaluation.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1377, doi. 10.1080/14756366.2021.1928111

By:

Salerno, Loredana;
Vanella, Luca;
Sorrenti, Valeria;
Consoli, Valeria;
Ciaffaglione, Valeria;
Fallica, Antonino N.;
Canale, Vittorio;
Zajdel, Paweł;
Pignatello, Rosario;
Intagliata, Sebastiano

Publication type:

Article

How does binding of imidazole-based inhibitors to heme oxygenase-1 influence their conformation? Insights combining crystal structures and molecular modelling.

Published in:

Acta Crystallographica Section B: Structural Science, Crystal Engineering & Materials, 2015, v. 71, n. 4, p. 447, doi. 10.1107/S2052520615010410

By:

Carletta, Andrea;
Tilborg, Anaëlle;
Moineaux, Laurence;
de Ruyck, Jérôme;
Basile, Livia;
Salerno, Loredana;
Romeo, Giuseppe;
Wouters, Johan;
Guccione, Salvatore

Publication type:

Article