Works matching AU Salah, Eidarus

Results: 21

Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation.

Published in:

PLoS Biology, 2010, v. 8, n. 7, p. 1, doi. 10.1371/journal.pbio.1000426

By:

Rellos, Peter;
Pike, Ashley C. W.;
Niesen, Frank H.;
Salah, Eidarus;
Wen Hwa Lee;
von Delft, Frank;
Knapp, Stefan

Publication type:

Article

JmjC catalysed histone H2a N-methyl arginine demethylation and C4-arginine hydroxylation reveals importance of sequence-reactivity relationships.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07183-5

By:

Bonnici, Joanna;
Oueini, Razanne;
Salah, Eidarus;
Johansson, Catrine;
Pires, Elisabete;
Abboud, Martine;
Dawber, Robert S.;
Tumber, Anthony;
Rabe, Patrick;
Saraç, Hilal;
Schofield, Christopher J.;
Kawamura, Akane

Publication type:

Article

2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26673-2

By:

Nakashima, Yu;
Brewitz, Lennart;
Tumber, Anthony;
Salah, Eidarus;
Schofield, Christopher J.

Publication type:

Article

The catalytic domains of all human KDM5 JmjC demethylases catalyse N‐methyl arginine demethylation.

Published in:

FEBS Letters, 2023, v. 597, n. 7, p. 933, doi. 10.1002/1873-3468.14586

By:

Bonnici, Joanna;
Oueini, Razanne;
Salah, Eidarus;
Johansson, Catrine;
Schofield, Christopher J.;
Kawamura, Akane

Publication type:

Article

Cyclic β²,³-amino acids improve the serum stability of macrocyclic peptide inhibitors targeting the SARS-CoV-2 main protease.

Published in:

Bulletin of the Chemical Society of Japan, 2024, v. 97, n. 5, p. 1, doi. 10.1093/bulcsj/uoae018

By:

Takashi Miura;
Malla, Tika R.;
Brewitz, Lennart;
Tumber, Anthony;
Salah, Eidarus;
Kang Ju Lee;
Naohiro Terasaka;
Owen, C. David;
Damerell, Claire Strain;
Lukacik, Petra;
Walsh, Martin A.;
Akane Kawamura;
Schofield, Christopher J.;
Takayuki Katoh;
Hiroaki Suga

Publication type:

Article

Substrate selectivity and inhibition of the human lysyl hydroxylase JMJD7.

Published in:

Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 10, p. 1, doi. 10.1002/pro.5162

By:

Bilgin, Nurgül;
Tumber, Anthony;
Dhingra, Siddhant;
Salah, Eidarus;
Al‐Salmy, Aziza;
Martín, Sandra Pinzón;
Wang, Yicheng;
Schofield, Christopher J.;
Mecinović, Jasmin

Publication type:

Article

Innenrücktitelbild: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. 40/2024).

Published in:

Angewandte Chemie, 2024, v. 136, n. 40, p. 1, doi. 10.1002/ange.202414504

By:

Wu, Yue;
Chen, Yafen;
Corner, Thomas P.;
Nakashima, Yu;
Salah, Eidarus;
Li, Zhihong;
Zhang, Linjian;
Yang, Le;
Tumber, Anthony;
Sun, Zhuoli;
Wen, Yukang;
Zhong, Ailin;
Yang, Fulai;
Li, Xiang;
Zhang, Zhihong;
Schofield, Christopher J.;
Zhang, Xiaojin

Publication type:

Article

A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity.

Published in:

Angewandte Chemie, 2024, v. 136, n. 40, p. 1, doi. 10.1002/ange.202410438

By:

Wu, Yue;
Chen, Yafen;
Corner, Thomas P.;
Nakashima, Yu;
Salah, Eidarus;
Li, Zhihong;
Zhang, Linjian;
Yang, Le;
Tumber, Anthony;
Sun, Zhuoli;
Wen, Yukang;
Zhong, Ailin;
Yang, Fulai;
Li, Xiang;
Zhang, Zhihong;
Schofield, Christopher J.;
Zhang, Xiaojin

Publication type:

Article

Formaldehyde reacts with N-terminal proline residues to give bicyclic aminals.

Published in:

Communications Chemistry, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42004-022-00801-5

By:

John, Tobias;
Pires, Elisabete;
Hester, Svenja S.;
Salah, Eidarus;
Hopkinson, Richard J.;
Schofield, Christopher J.

Publication type:

Article

Reading and erasing of the phosphonium analogue of trimethyllysine by epigenetic proteins.

Published in:

Communications Chemistry, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42004-022-00640-4

By:

Belle, Roman;
Kamps, Jos J. A. G.;
Poater, Jordi;
Kumar, Kiran;
Pieters, Bas J. G. E.;
Salah, Eidarus;
Claridge, Timothy D. W.;
Paton, Robert S.;
Bickelhaupt, F. Matthias;
Kawamura, Akane;
Schofield, Christopher J.;
Mecinović, Jasmin

Publication type:

Article

Reading and erasing of the phosphonium analogue of trimethyllysine by epigenetic proteins.

Published in:

Communications Chemistry, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42004-022-00640-4

By:

Belle, Roman;
Kamps, Jos J. A. G.;
Poater, Jordi;
Kumar, Kiran;
Pieters, Bas J. G. E.;
Salah, Eidarus;
Claridge, Timothy D. W.;
Paton, Robert S.;
Bickelhaupt, F. Matthias;
Kawamura, Akane;
Schofield, Christopher J.;
Mecinović, Jasmin

Publication type:

Article

Conformational plasticity of the ULK3 kinase domain.

Published in:

Biochemical Journal, 2021, v. 478, n. 14, p. 2811, doi. 10.1042/BCJ20210257

By:

Mathea, Sebastian;
Salah, Eidarus;
Tallant, Cynthia;
Chatterjee, Deep;
Berger, Benedict-Tilman;
Konietzny, Rebecca;
Müller, Susanne;
Kessler, Benedikt M.;
Knapp, Stefan

Publication type:

Article

Lessons from LIMK1 enzymology and their impact on inhibitor design.

Published in:

Biochemical Journal, 2019, v. 476, n. 21, p. 3197, doi. 10.1042/BCJ20190517

By:

Salah, Eidarus;
Chatterjee, Deep;
Beltrami, Alessandra;
Tumber, Anthony;
Preuss, Franziska;
Canning, Peter;
Chaikuad, Apirat;
Knaus, Petra;
Knapp, Stefan;
Bullock, Alex N.;
Mathea, Sebastian

Publication type:

Article

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.

Published in:

Nature, 2014, v. 508, n. 7495, p. 222, doi. 10.1038/nature13194

By:

Huber, Kilian V. M.;
Salah, Eidarus;
Radic, Branka;
Gridling, Manuela;
Elkins, Jonathan M.;
Stukalov, Alexey;
Jemth, Ann-Sofie;
Göktürk, Camilla;
Sanjiv, Kumar;
Strömberg, Kia;
Pham, Therese;
Berglund, Ulrika Warpman;
Colinge, Jacques;
Bennett, Keiryn L.;
Loizou, Joanna I.;
Helleday, Thomas;
Knapp, Stefan;
Superti-Furga, Giulio

Publication type:

Article

Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.13909

By:

Coutandin, Daniel;
Osterburg, Christian;
Srivastav, Ratnesh Kumar;
Sumyk, Manuela;
Kehrloesser, Sebastian;
Gebel, Jakob;
Tuppi, Marcel;
Hannewald, Jens;
Schäfer, Birgit;
Salah, Eidarus;
Mathea, Sebastian;
Müller-Kuller, Uta;
Doutch, James;
Grez, Manuel;
Knapp, Stefan;
Dötsch, Volker

Publication type:

Article

Crystallographic and Selectivity Studies on the Approved HIF Prolyl Hydroxylase Inhibitors Desidustat and Enarodustat.

Published in:

ChemMedChem, 2024, v. 19, n. 24, p. 1, doi. 10.1002/cmdc.202400504

By:

Corner, Thomas P.;
Salah, Eidarus;
Tumber, Anthony;
Kaur, Samanpreet;
Nakashima, Yu;
Allen, Mark D.;
Schnaubelt, Lara I.;
Fiorini, Giorgia;
Brewitz, Lennart;
Schofield, Christopher J.

Publication type:

Article

Structure‐Activity Studies Reveal Scope for Optimisation of Ebselen‐Type Inhibition of SARS‐CoV‐2 Main Protease.

Published in:

ChemMedChem, 2022, v. 17, n. 4, p. 1, doi. 10.1002/cmdc.202100582

By:

Thun‐Hohenstein, Siegfried T. D.;
Suits, Timothy F.;
Malla, Tika R.;
Tumber, Anthony;
Brewitz, Lennart;
Choudhry, Hani;
Salah, Eidarus;
Schofield, Christopher J.

Publication type:

Article

Synthesis of Novel Pyridine‐Carboxylates as Small‐Molecule Inhibitors of Human Aspartate/Asparagine‐β‐Hydroxylase.

Published in:

ChemMedChem, 2020, v. 15, n. 13, p. 1139, doi. 10.1002/cmdc.202000147

By:

Brewitz, Lennart;
Tumber, Anthony;
Thalhammer, Armin;
Salah, Eidarus;
Christensen, Kirsten E.;
Schofield, Christopher J.

Publication type:

Article

Comprehensive characterization of the Published Kinase Inhibitor Set.

Published in:

Nature Biotechnology, 2016, v. 34, n. 1, p. 95, doi. 10.1038/nbt.3374

By:

Elkins, Jonathan M;
Fedele, Vita;
Szklarz, Marta;
Abdul Azeez, Kamal R;
Salah, Eidarus;
Mikolajczyk, Jowita;
Romanov, Sergei;
Sepetov, Nikolai;
Huang, Xi-Ping;
Roth, Bryan L;
Al Haj Zen, Ayman;
Fourches, Denis;
Muratov, Eugene;
Tropsha, Alex;
Morris, Joel;
Teicher, Beverly A;
Kunkel, Mark;
Polley, Eric;
Lackey, Karen E;
Atkinson, Francis L

Publication type:

Article

Inside Back Cover: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. Int. Ed. 40/2024).

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 40, p. 1, doi. 10.1002/anie.202414504

By:

Wu, Yue;
Chen, Yafen;
Corner, Thomas P.;
Nakashima, Yu;
Salah, Eidarus;
Li, Zhihong;
Zhang, Linjian;
Yang, Le;
Tumber, Anthony;
Sun, Zhuoli;
Wen, Yukang;
Zhong, Ailin;
Yang, Fulai;
Li, Xiang;
Zhang, Zhihong;
Schofield, Christopher J.;
Zhang, Xiaojin

Publication type:

Article

A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 40, p. 1, doi. 10.1002/anie.202410438

By:

Wu, Yue;
Chen, Yafen;
Corner, Thomas P.;
Nakashima, Yu;
Salah, Eidarus;
Li, Zhihong;
Zhang, Linjian;
Yang, Le;
Tumber, Anthony;
Sun, Zhuoli;
Wen, Yukang;
Zhong, Ailin;
Yang, Fulai;
Li, Xiang;
Zhang, Zhihong;
Schofield, Christopher J.;
Zhang, Xiaojin

Publication type:

Article