Works by Sakamoto, Takeharu

Results: 30

Trans‐homophilic interaction of CADM1 promotes organ infiltration of T‐cell lymphoma by adhesion to vascular endothelium.

Published in:

Cancer Science, 2022, v. 113, n. 5, p. 1669, doi. 10.1111/cas.15307

By:

Kasai, Yutaka;
Gan, Siew Pey;
Funaki, Toko;
Ohashi‐Kumagai, Yuki;
Tominaga, Mizuki;
Shiu, Shu‐Jen;
Suzuki, Daisuke;
Matsubara, Daisuke;
Sakamoto, Takeharu;
Sakurai‐Yageta, Mika;
Ito, Takeshi;
Murakami, Yoshinori

Publication type:

Article

CHIP‐associated mutant ASXL1 in blood cells promotes solid tumor progression.

Published in:

Cancer Science, 2022, v. 113, n. 4, p. 1182, doi. 10.1111/cas.15294

By:

Liu, Xiaoxiao;
Sato, Naru;
Shimosato, Yuko;
Wang, Teh‐Wei;
Denda, Tamami;
Chang, Yu‐Hsuan;
Yabushita, Tomohiro;
Fujino, Takeshi;
Asada, Shuhei;
Tanaka, Yosuke;
Fukuyama, Tomofusa;
Enomoto, Yutaka;
Ota, Yasunori;
Sakamoto, Takeharu;
Kitamura, Toshio;
Goyama, Susumu

Publication type:

Article

Integrated functions of membrane-type 1 matrix metalloproteinase in regulating cancer malignancy: Beyond a proteinase.

Published in:

Cancer Science, 2017, v. 108, n. 6, p. 1095, doi. 10.1111/cas.13231

By:

Sakamoto, Takeharu;
Seiki, Motoharu

Publication type:

Article

Scaffold protein Lin7 family in membrane skeletal protein complex in mouse seminiferous tubules.

Published in:

Histochemistry & Cell Biology, 2019, v. 152, n. 5, p. 333, doi. 10.1007/s00418-019-01807-2

By:

Kamijo, Akio;
Saitoh, Yurika;
Sakamoto, Takeharu;
Kubota, Hiroshi;
Yamauchi, Junji;
Terada, Nobuo

Publication type:

Article

The membrane palmitoylated protein, MPP6, is involved in myelin formation in the mouse peripheral nervous system.

Published in:

Histochemistry & Cell Biology, 2019, v. 151, n. 5, p. 385, doi. 10.1007/s00418-018-1745-y

By:

Saitoh, Yurika;
Kamijo, Akio;
Yamauchi, Junji;
Sakamoto, Takeharu;
Terada, Nobuo

Publication type:

Article

Deficiency of a membrane skeletal protein, 4.1G, results in myelin abnormalities in the peripheral nervous system.

Published in:

Histochemistry & Cell Biology, 2017, v. 148, n. 6, p. 597, doi. 10.1007/s00418-017-1600-6

By:

Saitoh, Yurika;
Ohno, Nobuhiko;
Yamauchi, Junji;
Sakamoto, Takeharu;
Terada, Nobuo

Publication type:

Article

Munc18-1-interacting protein 3 mitigates renal fibrosis through protection of tubular epithelial cells from apoptosis.

Published in:

Nephrology Dialysis Transplantation, 2020, v. 35, n. 4, p. 576, doi. 10.1093/ndt/gfz177

By:

Nasu, Kahori;
Kawakami, Takahisa;
Shinohara, Akinari;
Sakamoto, Takeharu;
Nangaku, Masaomi

Publication type:

Article

TGF-β-dependent reprogramming of amino acid metabolism induces epithelial–mesenchymal transition in non-small cell lung cancers.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02323-7

By:

Nakasuka, Fumie;
Tabata, Sho;
Sakamoto, Takeharu;
Hirayama, Akiyoshi;
Ebi, Hiromichi;
Yamada, Tadaaki;
Umetsu, Ko;
Ohishi, Maki;
Ueno, Ayano;
Goto, Hisatsugu;
Sugimoto, Masahiro;
Nishioka, Yasuhiko;
Yamada, Yasuhiro;
Tomita, Masaru;
Sasaki, Atsuo T.;
Yano, Seiji;
Soga, Tomoyoshi

Publication type:

Article

Mint3 as a Potential Target for Cooling Down HIF-1α-Mediated Inflammation and Cancer Aggressiveness.

Published in:

Biomedicines, 2023, v. 11, n. 2, p. 549, doi. 10.3390/biomedicines11020549

By:

Tanaka, Noritaka;
Sakamoto, Takeharu

Publication type:

Article

MT1-MMP as a Key Regulator of Metastasis.

Published in:

Cells (2073-4409), 2023, v. 12, n. 17, p. 2187, doi. 10.3390/cells12172187

By:

Tanaka, Noritaka;
Sakamoto, Takeharu

Publication type:

Article

Hypoxia drives progression of multiple sclerosis by enhancing the inflammasome activation in macrophages with Porphyromonas gingivalis infection.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02548-z

By:

Okano, Tokuju;
Ashida, Hiroshi;
Tsukasaki, Masayuki;
Iida, Tamako;
Yamamoto, Masahiro;
Takayanagi, Hiroshi;
Sakamoto, Takeharu;
Suzuki, Toshihiko

Publication type:

Article

SHARPIN is a novel gene of colorectal cancer that promotes tumor growth potentially via inhibition of p53 expression.

Published in:

International Journal of Oncology, 2024, v. 65, n. 6, p. N.PAG, doi. 10.3892/ijo.2024.5701

By:

Nakano, Yusuke;
Masuda, Takaaki;
Sakamoto, Takeharu;
Tanaka, Noritaka;
Tobo, Taro;
Hashimoto, Masahiro;
Tatsumi, Takanari;
Saito, Hideyuki;
Takahashi, Junichi;
Koike, Kensuke;
Abe, Tadashi;
Ando, Yuki;
Ozato, Yuki;
Hosoda, Kiyotaka;
Hirose, Kosuke;
Higuchi, Satoshi;
Ikehara, Tomohiko;
Hisamatsu, Yuichi;
Toshima, Takeo;
Yonemura, Yusuke

Publication type:

Article

Involvement of membrane palmitoylated protein 6 (MPP6) in synapses of mouse cerebrum.

Published in:

Histochemistry & Cell Biology, 2025, v. 163, n. 1, p. 1, doi. 10.1007/s00418-025-02378-1

By:

Saitoh, Yurika;
Motofuji, Sayaka;
Kamijo, Akio;
Suzuki, Tatsuo;
Yoshizawa, Takahiro;
Sakamoto, Takeharu;
Kametani, Kiyokazu;
Terada, Nobuo

Publication type:

Article

Involvement of membrane palmitoylated protein 2 (MPP2) in the synaptic molecular complex at the mouse cerebellar glomerulus.

Published in:

Histochemistry & Cell Biology, 2022, v. 158, n. 5, p. 497, doi. 10.1007/s00418-022-02137-6

By:

Yamada, Tomoki;
Saitoh, Yurika;
Kametani, Kiyokazu;
Kamijo, Akio;
Sakamoto, Takeharu;
Terada, Nobuo

Publication type:

Article

Pharmacological inhibition of Mint3 attenuates tumour growth, metastasis, and endotoxic shock.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02701-1

By:

Sakamoto, Takeharu;
Fukui, Yuya;
Kondoh, Yasumitsu;
Honda, Kaori;
Shimizu, Takeshi;
Hara, Toshiro;
Hayashi, Tetsuro;
Saitoh, Yurika;
Murakami, Yoshinori;
Inoue, Jun-ichiro;
Kaneko, Shuichi;
Osada, Hiroyuki;
Seiki, Motoharu

Publication type:

Article

ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center.

Published in:

Cell Adhesion & Migration, 2011, v. 5, n. 1, p. 23, doi. 10.4161/cam.5.1.13492

By:

Nagano, Makoto;
Hoshino, Daisuke;
Sakamoto, Takeharu;
Akizawa, Toshifumi;
Koshikawa, Naohiko;
Seiki, Motoharu

Publication type:

Article

Hypoxia-Inducible Factor 1 Regulation through Cross Talk between mTOR and MT1-MMP.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 1, p. 30, doi. 10.1128/MCB.01169-13

By:

Sakamoto, Takeharu;
Weng, Jane S.;
Hara, Toshiro;
Yoshino, Seiko;
Kozuka-Hata, Hiroko;
Oyama, Masaaki;
Seiki, Motoharu

Publication type:

Article

Electron microscopic observation of photoreceptor cells in directly inserted anesthetized Drosophila into a high‐pressure freezing unit.

Published in:

Microscopy Research & Technique, 2019, v. 82, n. 3, p. 244, doi. 10.1002/jemt.23166

By:

Terada, Hitomi;
Saitoh, Yurika;
Kametani, Kiyokazu;
Sakaguchi, Masahiko;
Sakamoto, Takeharu;
Kamijo, Akio;
Terada, Nobuo

Publication type:

Article

EXOSC9 depletion attenuates P-body formation, stress resistance, and tumorigenicity of cancer cells.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-66455-2

By:

Yoshino, Seiko;
Matsui, Yusuke;
Fukui, Yuya;
Seki, Masahide;
Yamaguchi, Kiyoshi;
Kanamori, Akane;
Saitoh, Yurika;
Shimamura, Teppei;
Suzuki, Yutaka;
Furukawa, Yoichi;
Kaneko, Shuichi;
Seiki, Motoharu;
Murakami, Yoshinori;
Inoue, Jun-ichiro;
Sakamoto, Takeharu

Publication type:

Article

Cytoplasmic tail of MT1-MMP regulates macrophage motility independently from its protease activity.

Published in:

Genes to Cells, 2009, v. 14, n. 5, p. 617, doi. 10.1111/j.1365-2443.2009.01293.x

By:

Sakamoto, Takeharu;
Seiki, Motoharu

Publication type:

Article

Establishment of an MT4-MMP-deficient mouse strain representing an efficient tracking system for MT4-MMP/MMP-17 expression in vivo using β-galactosidase.

Published in:

Genes to Cells, 2007, v. 12, n. 9, p. 1091, doi. 10.1111/j.1365-2443.2007.01110.x

By:

Rikimaru, Akiko;
Komori, Kiyoshi;
Sakamoto, Takeharu;
Ichise, Hirotake;
Yoshida, Nobuaki;
Yana, Ikuo;
Seiki, Motoharu

Publication type:

Article

Investigation of a MMP-2 Activity-Dependent Anchoring Probe for Nuclear Imaging of Cancer.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0102180

By:

Temma, Takashi;
Hanaoka, Hirofumi;
Yonezawa, Aki;
Kondo, Naoya;
Sano, Kohei;
Sakamoto, Takeharu;
Seiki, Motoharu;
Ono, Masahiro;
Saji, Hideo

Publication type:

Article

Genetic Screening of New Genes Responsible for Cellular Adaptation to Hypoxia Using a Genome-Wide shRNA Library.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035590

By:

Yoshino, Seiko;
Hara, Toshiro;
Weng, Jane S.;
Takahashi, Yuka;
Seiki, Motoharu;
Sakamoto, Takeharu

Publication type:

Article

Mint3 as a Molecular Target Activated in the Early Stage of Hepatocarcinogenesis.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1430, doi. 10.3390/ijms26041430

By:

Nishitani, Masaki;
Okada, Hikari;
Nio, Kouki;
Hayashi, Tomoyuki;
Terashima, Takeshi;
Iida, Noriho;
Shimakami, Tetsuro;
Takatori, Hajime;
Honda, Masao;
Kaneko, Shuichi;
Sakamoto, Takeharu;
Yamashita, Taro

Publication type:

Article

IGSF3 is a homophilic cell adhesion molecule that drives lung metastasis of melanoma by promoting adhesion to vascular endothelium.

Published in:

Cancer Science, 2024, v. 115, n. 6, p. 1936, doi. 10.1111/cas.16166

By:

Guo, Yue;
Kasai, Yutaka;
Tanaka, Yuto;
Ohashi‐Kumagai, Yuki;
Sakamoto, Takeharu;
Ito, Takeshi;
Murakami, Yoshinori

Publication type:

Article

Recent Progress on Genetically Modified Animal Models for Membrane Skeletal Proteins: The 4.1 and MPP Families.

Published in:

Genes, 2023, v. 14, n. 10, p. 1942, doi. 10.3390/genes14101942

By:

Terada, Nobuo;
Saitoh, Yurika;
Saito, Masaki;
Yamada, Tomoki;
Kamijo, Akio;
Yoshizawa, Takahiro;
Sakamoto, Takeharu

Publication type:

Article

Mint3/Apba3 depletion ameliorates severe murine influenza pneumonia and macrophage cytokine production in response to the influenza virus.

Published in:

Scientific Reports, 2016, p. 37815, doi. 10.1038/srep37815

By:

Uematsu, Takayuki;
Fujita, Tomoko;
Nakaoka, Hiroki J.;
Hara, Toshiro;
Kobayashi, Noritada;
Murakami, Yoshinori;
Seiki, Motoharu;
Sakamoto, Takeharu

Publication type:

Article

NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells.

Published in:

Scientific Reports, 2016, p. 22784, doi. 10.1038/srep22784

By:

Nakaoka, Hiroki J.;
Hara, Toshiro;
Yoshino, Seiko;
Kanamori, Akane;
Matsui, Yusuke;
Shimamura, Teppei;
Sato, Hiroshi;
Murakami, Yoshinori;
Seiki, Motoharu;
Sakamoto, Takeharu

Publication type:

Article

Mint3-depletion-induced energy stress sensitizes triple-negative breast cancer to chemotherapy via HSF1 inactivation.

Published in:

Cell Death & Disease, 2023, v. 14, n. 12, p. 1, doi. 10.1038/s41419-023-06352-4

By:

Tanaka, Noritaka;
Okada, Hikari;
Yamaguchi, Kiyoshi;
Seki, Masahide;
Matsubara, Daisuke;
Gotoh, Noriko;
Suzuki, Yutaka;
Furukawa, Yoichi;
Yamashita, Taro;
Inoue, Jun-ichiro;
Kaneko, Shuichi;
Sakamoto, Takeharu

Publication type:

Article

Mint3 depletion-mediated glycolytic and oxidative alterations promote pyroptosis and prevent the spread of Listeria monocytogenes infection in macrophages.

Published in:

Cell Death & Disease, 2021, v. 12, n. 4, p. 1, doi. 10.1038/s41419-021-03691-y

By:

Uematsu, Takayuki;
Tsuchiya, Kohsuke;
Kobayashi, Noritada;
Seiki, Motoharu;
Inoue, Jun-ichiro;
Kaneko, Shuichi;
Sakamoto, Takeharu

Publication type:

Article