Works by Sakagami, Hiroshi

Results: 91

Multi-Omics Analysis of Anti-Inflammatory Action of Alkaline Extract of the Leaves of Sasa sp.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 10, p. 2100, doi. 10.3390/jcm10102100

By:

Sakagami, Hiroshi;
Nakatani, Sachie;
Enomoto, Ayame;
Ota, Sana;
Kaneko, Miku;
Sugimoto, Masahiro;
Horiuchi, Misaki;
Toeda, Kazuki;
Oizumi, Takaaki;
Petricoin, Emanuel F.

Publication type:

Article

New Megastigmane and Polyphenolic Components of Henna Leaves and Their Tumor-Specific Cytotoxicity on Human Oral Squamous Carcinoma Cell Lines.

Published in:

Antioxidants, 2023, v. 12, n. 11, p. 1951, doi. 10.3390/antiox12111951

By:

Orabi, Mohamed A. A.;
Orabi, Esam A.;
Awadh, Ahmed Abdullah Al;
Alshahrani, Mohammed Merae;
Abdel-Wahab, Basel A.;
Sakagami, Hiroshi;
Hatano, Tsutomu

Publication type:

Article

Tetrahydrobiopterin impairs the action of endothelial nitric oxide via superoxide derived from platelets.

Published in:

British Journal of Pharmacology, 2000, v. 131, n. 5, p. 958, doi. 10.1038/sj.bjp.0703648

By:

Tajima, Masamichi;
Sakagami, Hiroshi

Publication type:

Article

ACE2: The Key Molecule for Understanding the Pathophysiology of Severe and Critical Conditions of COVID-19: Demon or Angel?

Published in:

Viruses (1999-4915), 2020, v. 12, n. 5, p. 491, doi. 10.3390/v12050491

By:

Xiao, Li;
Sakagami, Hiroshi;
Miwa, Nobuhiko

Publication type:

Article

Hypoxia and reoxygenation augment bone-resorbing factor production from human periodontal ligament cells.

Published in:

2007

By:

Motohira, Hitoshi;
Hayashi, Joichiro;
Tatsumi, Junichi;
Tajima, Masamichi;
Sakagami, Hiroshi;
Shin, Kitetsu

Publication type:

journal article

A new and 23 known cardenolide glycosides from Thevetia neriifolia seeds and their cytotoxic activities against human oral carcinoma cell lines.

Published in:

Natural Product Research, 2021, v. 35, n. 22, p. 4388, doi. 10.1080/14786419.2020.1716352

By:

Tatsuno, Satoru;
Iguchi, Tomoki;
Kuroda, Minpei;
Ishihara, Mai;
Sakagami, Hiroshi;
Mimaki, Yoshihiro

Publication type:

Article

Steroidal constituents isolated from the seeds of Withania somnifera.

Published in:

Natural Product Research, 2021, v. 35, n. 13, p. 2205, doi. 10.1080/14786419.2019.1667351

By:

Iguchi, Tomoki;
Kuroda, Minpei;
Ishihara, Mai;
Sakagami, Hiroshi;
Mimaki, Yoshihiro

Publication type:

Article

Does Ortho-Substitution Enhance Cytotoxic Potencies in a Series of 3,5-Bis(benzylidene)-4-piperidones?

Published in:

Medicines, 2024, v. 11, n. 8, p. 19, doi. 10.3390/medicines11080019

By:

Karki, Subhas S.;
Das, Umashankar;
Balzarini, Jan;
De Clercq, Erik;
Sakagami, Hiroshi;
Uesawa, Yoshihiro;
Roayapalley, Praveen K.;
Dimmock, Jonathan R.

Publication type:

Article

Medicines—Aims and Scope Updates.

Published in:

Medicines, 2024, v. 11, n. 5, p. 11, doi. 10.3390/medicines11050011

By:

Sakagami, Hiroshi

Publication type:

Article

Dimeric 3,5-Bis(benzylidene)-4-piperidones: Tumor-Selective Cytotoxicity and Structure-Activity Relationships.

Published in:

Medicines, 2024, v. 11, n. 1, p. 3, doi. 10.3390/medicines11010003

By:

Das, Swagatika;
Roayapalley, Praveen K.;
Sakagami, Hiroshi;
Umemura, Naoki;
Gorecki, Dennis K. J.;
Hossain, Mohammad;
Kawase, Masami;
Das, Umashankar;
Dimmock, Jonathan R.

Publication type:

Article

A Comparative Study of Tumor-Specificity and Neurotoxicity between 3-Styrylchromones and Anti-Cancer Drugs.

Published in:

Medicines, 2023, v. 10, n. 7, p. 43, doi. 10.3390/medicines10070043

By:

Abe, Tomoyuki;
Sakagami, Hiroshi;
Amano, Shigeru;
Uota, Shin;
Bandow, Kenjiro;
Uesawa, Yoshihiro;
U, Shiori;
Shibata, Hiroki;
Takemura, Yuri;
Kimura, Yu;
Takao, Koichi;
Sugita, Yoshiaki;
Sato, Akira;
Tanuma, Sei-ichi;
Takeshima, Hiroshi

Publication type:

Article

Dichloroacetyl Amides of 3,5-Bis(benzylidene)-4-piperidones Displaying Greater Toxicity to Neoplasms than to Non-Malignant Cells.

Published in:

Medicines, 2022, v. 9, n. 6, p. 1, doi. 10.3390/medicines9060035

By:

Hossain, Mohammad;
Roayapalley, Praveen K.;
Hiroshi Sakagami;
Keitaro Satoh;
Kenjiro Bandow;
Das, Umashankar;
Dimmock, Jonathan R.

Publication type:

Article

Feiyanning Formula Induces Apoptosis of Lung Adenocarcinoma Cells by Activating the Mitochondrial Pathway.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.690878

By:

Zhu, Li-Min;
Shi, Hai-Xia;
Sugimoto, Masahiro;
Bandow, Kenjiro;
Sakagami, Hiroshi;
Amano, Shigeru;
Deng, Hai-Bin;
Ye, Qing-Yu;
Gai, Yun;
Xin, Xiao-Li;
Xu, Zhen-Ye

Publication type:

Article

Antileishmanial and lung adenocarcinoma cell toxicity of Withania somnifera (Linn.) dunal root and fruit extracts.

Published in:

Natural Product Research, 2022, v. 36, n. 16, p. 4231, doi. 10.1080/14786419.2021.1973462

By:

Orabi, Mohamed A. A.;
Zidan, Sabry A. H.;
Sakagami, Hiroshi;
Murakami, Yukio;
Ali, Ashraf A.;
Alyami, Hamad S.;
Alshabi, Ali Mohamed;
Matsunami, Katsuyoshi

Publication type:

Article

The contact Nd:YAG laser system in the treatment of bladder cancer: a preliminary report in 48 patients.

Published in:

1987

By:

Washida, Hiroto;
Watanabe, Hideki;
Sakagami, Hiroshi;
Sasaki, Syoichi;
Daikuzono, Norio;
Washida, H;
Watanabe, H;
Sakagami, H;
Sasaki, S;
Daikuzono, N

Publication type:

journal article

Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1722, doi. 10.1080/14756366.2019.1670657

By:

Bilginer, Sinan;
Gul, Halise Inci;
Erdal, Feyza Sena;
Sakagami, Hiroshi;
Levent, Serkan;
Gulcin, Ilhami;
Supuran, Claudiu T.

Publication type:

Article

Microwave-assisted synthesis and bioevaluation of new sulfonamides.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 369, doi. 10.1080/14756366.2016.1254207

By:

Gul, Halise Inci;
Yamali, Cem;
Yesilyurt, Fatma;
Sakagami, Hiroshi;
Kucukoglu, Kaan;
Gulcin, Ilhami;
Gul, Mustafa;
Supuran, Claudiu T.

Publication type:

Article

Designing, synthesis and bioactivities of 4-[3-(4-hydroxyphenyl)-5-aryl-4,5-dihydro-pyrazol-1-yl]benzenesulfonamides.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 169, doi. 10.1080/14756366.2016.1243536

By:

Gul, Halise Inci;
Mete, Ebru;
Eren, Sakip Emre;
Sakagami, Hiroshi;
Yamali, Cem;
Supuran, Claudiu T.

Publication type:

Article

Synthesis and bioactivities of halogen bearing phenolic chalcones and their corresponding bis Mannich bases.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, p. 125, doi. 10.1080/14756366.2016.1221825

By:

Yamali, Cem;
Gul, Halise Inci;
Sakagami, Hiroshi;
Supuran, Claudiu T.

Publication type:

Article

Synthesis, cytotoxicity and carbonic anhydrase inhibitory activities of new pyrazolines.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, p. 20, doi. 10.1080/14756366.2016.1217852

By:

Kucukoglu, Kaan;
Oral, Fatih;
Aydin, Tevfik;
Yamali, Cem;
Algul, Oztekin;
Sakagami, Hiroshi;
Gulcin, Ilhami;
Supuran, Claudiu T.;
Gul, Halise Inci

Publication type:

Article

Synthesis and bioactivity studies of 1-aryl-3-(2-hydroxyethylthio)-1- propanones.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, p. 105, doi. 10.1080/14756366.2016.1209495

By:

Unluer, Elif;
Gul, Halise Inci;
Demirtas, Alkan;
Sakagami, Hiroshi;
Umemura, Naoki;
Tanc, Muhammet;
Kazaz, Cavit;
Supuran, Claudiu T.

Publication type:

Article

Synthesis and bioactivity studies of 1-aryl-3-(2-hydroxyethylthio)-1-propanones.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, p. 105, doi. 10.1080/14756366.2016.1209495

By:

Unluer, Elif;
Gul, Halise Inci;
Demirtas, Alkan;
Sakagami, Hiroshi;
Umemura, Naoki;
Tanc, Muhammet;
Kazaz, Cavit;
Supuran, Claudiu T.

Publication type:

Article

Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3 H -indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1619, doi. 10.3109/14756366.2016.1160077

By:

Gul, Halise Inci;
Tugrak, Mehtap;
Sakagami, Hiroshi;
Taslimi, Parham;
Gulcin, Ilhami;
Supuran, Claudiu T.

Publication type:

Article

Niacin esters of chalcones with tumor-selective properties.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1451, doi. 10.3109/14756366.2016.1144595

By:

Panda, Atulya K.;
Das, Umashankar;
Roayapalley, Praveen K.;
Sakagami, Hiroshi;
Kawase, Masami;
Balzarini, Jan;
De Clercq, Erik;
Dimmock, Jonathan R.

Publication type:

Article

Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1375, doi. 10.3109/14756366.2016.1140755

By:

Inci Gul, Halise;
Yamali, Cem;
Tugce Yasa, Asiye;
Unluer, Elif;
Sakagami, Hiroshi;
Tanc, Muhammet;
Supuran, Claudiu T.

Publication type:

Article

Synthesis of mono Mannich bases of 2-(4-hydroxybenzylidene)-2,3-dihydroinden-1-one and evaluation of their cytotoxicities.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 5, p. 818, doi. 10.3109/14756366.2015.1070263

By:

Tugrak, Mehtap;
Yamali, Cem;
Sakagami, Hiroshi;
Gul, Halise Inci

Publication type:

Article

Synthesis of some acrylophenones with N -methylpiperazine and evaluation of their cytotoxicities.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 1, p. 147, doi. 10.3109/14756366.2015.1014474

By:

Gul, Halise Inci;
Tugrak, Mehtap;
Sakagami, Hiroshi

Publication type:

Article

Synthesis and biological evaluation of 1,5-bis(4-hydroxy-3-methoxyphenyl)penta-1,4-dien-3-one and its aminomethyl derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2015, v. 30, n. 3, p. 383, doi. 10.3109/14756366.2014.940934

By:

Yerdelen, Kadir Ozden;
Gul, Halise Inci;
Sakagami, Hiroshi;
Umemura, Naoki

Publication type:

Article

1-(3-Aminomethyl-4-hydroxyphenyl)-3-pyridinyl-2-propen-1-ones: A novel group of tumour-selective cytotoxins.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2013, v. 28, n. 5, p. 974, doi. 10.3109/14756366.2012.700927

By:

Bilginer, Sinan;
Gul, Halise Inci;
Mete, Ebru;
Das, Umashankar;
Sakagami, Hiroshi;
Umemura, Naoki;
Dimmock, Jonathan Richard

Publication type:

Article

A comparative in vitro efficacy of conventional rotatory and chemomechanical caries removal: Influence on cariogenic flora, microhardness, and residual composition.

Published in:

Journal of Conservative Dentistry, 2014, v. 17, n. 6, p. 536, doi. 10.4103/0972-0707.144588

By:

Garcia-Contreras, Rene;
Scougall-Vilchis, Rogelio Jose;
Contreras-Bulnes, Rosalia;
Hiroshi Sakagami;
Morales-Luckie, Raul Alberto;
Hiroshi Nakajima

Publication type:

Article

Isolation of Pro-Osteogenic Compounds from Euptelea polyandra That Reciprocally Regulate Osteoblast and Osteoclast Differentiation.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 24, p. 17479, doi. 10.3390/ijms242417479

By:

Suzuki, Ryuichiro;
Shirataki, Yoshiaki;
Tomomura, Akito;
Bandow, Kenjiro;
Sakagami, Hiroshi;
Tomomura, Mineko

Publication type:

Article

A Dual Anti-Inflammatory and Anti-Proliferative 3-Styrylchromone Derivative Synergistically Enhances the Anti-Cancer Effects of DNA-Damaging Agents on Colon Cancer Cells by Targeting HMGB1-RAGE-ERK1/2 Signaling.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 3426, doi. 10.3390/ijms23073426

By:

Tanuma, Sei-ichi;
Oyama, Takahiro;
Okazawa, Miwa;
Yamazaki, Hiroaki;
Takao, Koichi;
Sugita, Yoshiaki;
Amano, Shigeru;
Abe, Takehiko;
Sakagami, Hiroshi

Publication type:

Article

Tumor-Specificity, Neurotoxicity, and Possible Involvement of the Nuclear Receptor Response Pathway of 4,6,8-Trimethyl Azulene Amide Derivatives.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 5, p. 2601, doi. 10.3390/ijms23052601

By:

Naitoh, Kotone;
Orihara, Yuta;
Sakagami, Hiroshi;
Miura, Takumi;
Satoh, Keitaro;
Amano, Shigeru;
Bandow, Kenjiro;
Iijima, Yosuke;
Kurosaki, Kota;
Uesawa, Yoshihiro;
Hashimoto, Masashi;
Wakabayashi, Hidetsugu

Publication type:

Article

Plasma pteridine concentrations in patients with chronic renal failure.

Published in:

Nephrology Dialysis Transplantation, 2002, v. 17, n. 6, p. 1032, doi. 10.1093/ndt/17.6.1032

By:

Yokoyama, Keitaro;
Tajima, Masamich;
Yoshida, Hiraku;
Nakayama, Masaaki;
Tokutome, Goro;
Sakagami, Hiroshi;
Hosoya, Tatsuo

Publication type:

Article

Hyaluronan induces odontoblastic differentiation of dental pulp stem cells via CD44.

Published in:

Stem Cell Research & Therapy, 2016, v. 7, p. 1, doi. 10.1186/s13287-016-0399-8

By:

Naoki Umemura;
Emika Ohkoshi;
Masamichi Tajima;
Hirotaka Kikuchi;
Tadashi Katayama;
Hiroshi Sakagami

Publication type:

Article

Metabolomic profiling of sodium fluoride-induced cytotoxicity in an oral squamous cell carcinoma cell line.

Published in:

Metabolomics, 2014, v. 10, n. 2, p. 270, doi. 10.1007/s11306-013-0576-z

By:

Sakagami, Hiroshi;
Sugimoto, Masahiro;
Tanaka, Shoji;
Onuma, Hiromi;
Ota, Sana;
Kaneko, Miku;
Soga, Tomoyoshi;
Tomita, Masaru

Publication type:

Article

Non-targeted metabolite profiling in activated macrophage secretion.

Published in:

Metabolomics, 2012, v. 8, n. 4, p. 624, doi. 10.1007/s11306-011-0353-9

By:

Sugimoto, Masahiro;
Sakagami, Hiroshi;
Yokote, Yoshiko;
Onuma, Hiromi;
Kaneko, Miku;
Mori, Masayo;
Sakaguchi, Yasuko;
Soga, Tomoyoshi;
Tomita, Masaru

Publication type:

Article

Induction of Apoptosis in Human Eosinophilic Leukemic Cell Line (EOL-1).

Published in:

International Archives of Allergy & Immunology, 1997, v. 114, n. S1, p. 84, doi. 10.1159/000237727

By:

Noda, Hiromichi;
Sakagami, Hiroshi;
Kokubu, Fumio;
Kurokawa, Masatsugu;
Tokunaga, Hisahiro;
Takeda, Minoru;
Adachi, Mitsuru

Publication type:

Article

Biological Activities and Drug-Likeness Properties of Phenol-Based Heterocyclic Compounds.

Published in:

Pharmaceutical Chemistry Journal, 2024, v. 57, n. 11, p. 1754, doi. 10.1007/s11094-024-03076-3

By:

Yamali, Cem;
Nenni, Merve;
Sakarya, Mehtap Tugrak;
Sakagami, Hiroshi;
Gul, Halise Inci

Publication type:

Article

Anatomical and electrophysiological mechanisms for asymmetrical excitatory propagation in the rat insular cortex: In vivo optical imaging and whole-cell patch-clamp studies.

Published in:

Journal of Comparative Neurology, 2013, v. 521, n. 7, p. 1598, doi. 10.1002/cne.23246

By:

Adachi, Kazunori;
Fujita, Satoshi;
Yoshida, Atsushi;
Sakagami, Hiroshi;
Koshikawa, Noriaki;
Kobayashi, Masayuki

Publication type:

Article

Three new flavonoids, proanthocyanidin, and accompanying phenolic constituents from Feijoa sellowiana.

Published in:

Bioscience, Biotechnology & Biochemistry, 2018, v. 82, n. 1, p. 31, doi. 10.1080/09168451.2017.1412246

By:

Aoyama, Hiroe;
Sakagami, Hiroshi;
Hatano, Tsutomu

Publication type:

Article

Metabolomic profiling of tumor-infiltrating macrophages during tumor growth.

Published in:

Cancer Immunology, Immunotherapy, 2020, v. 69, n. 11, p. 2357, doi. 10.1007/s00262-020-02622-8

By:

Umemura, Naoki;
Sugimoto, Masahiro;
Kitoh, Yusuke;
Saio, Masanao;
Sakagami, Hiroshi

Publication type:

Article

Visit to UWC, and presentation of Anti-UVC potential of Rooibos in SAJU6.

Published in:

New Food Industry, 2024, v. 66, n. 12, p. 763

By:

Koji Sakiyama;
Hiroshi Sakagami;
Satoshi Kawano;
Katsuyuki Ohtomo;
Maki Izawa;
Yusei Otaka;
Shinji Kito;
Hiroshi Nakajima;
Shu Fujiwara;
Izumi Den;
Jun Miyata;
Katsuyoshi Sunaga;
Ryuichiro Suzuki;
Suvarna Indermun;
Veerasamy Yengopal;
Umesh Bawa;
Ghaleeb Jeppie

Publication type:

Article

Identification of Potent Anti-tumor, Anti-viral and Anti-UVC Entities among Hundreds of Natural and Synthetic Products.

Published in:

New Food Industry, 2024, v. 66, n. 6, p. 369

By:

Hiroshi Sakagami

Publication type:

Article

Bridging Mexico and Japan: Exploring the Significance of Research Stays.

Published in:

New Food Industry, 2023, v. 65, n. 11, p. 664

By:

Lopez-Ayuso, Christian Andrea;
Shin Uota;
Acra, Alejandro Mena;
Masahiko Kobayashi;
Acosta-Torres, Laura Susana;
Garcia-Contreras, Rene;
Hiroshi Sakagami

Publication type:

Article

JAPANESE AND MEXICAN FOOD.

Published in:

New Food Industry, 2023, v. 65, n. 4, p. 227

By:

Acra, Alejandro Mena;
Shin Uota;
Hiroshi Sakagami

Publication type:

Article

Age‐ and Periodontal Disease Independent Correlation of Salivary Amino Acids.

Published in:

In Vivo, 2025, v. 39, n. 3, p. 1237, doi. 10.21873/invivo.13928

By:

SHOJI TANAKA;
HIROSHI SAKAGAMI;
MASAHIRO SUGIMOTO

Publication type:

Article

Potential Medicinal Efficacy of Alkaline Extract of Pine Seed Shell: Anti-UVC Activity and Macrophage Activation.

Published in:

In Vivo, 2024, v. 38, n. 6, p. 2629, doi. 10.21873/invivo.13739

By:

ACRA, ALEJANDRO MENA;
SHIN UOTA;
MASAAKI YOSHIHARA;
YUKIO MURAKAMI;
HIROSHI SAKAGAMI

Publication type:

Article

Augmentation of Therapeutic Efficacy of Extraction of Causative Teeth by Irrigation for Odontogenic Maxillary Sinusitis.

Published in:

In Vivo, 2024, v. 38, n. 3, p. 1236, doi. 10.21873/invivo.13560

By:

TAKAO KATO;
HIROSHI SAKAGAMI

Publication type:

Article

Dectin-1/SYK Activation Induces Antimicrobial Peptide and Negative Regulator of NF-κB Signaling in Human Oral Epithelial Cells.

Published in:

In Vivo, 2024, v. 38, n. 3, p. 1042, doi. 10.21873/invivo.13537

By:

MEGUMI INOMATA;
MASAYO ABE;
YASUKO KAWASE;
TORU HAYASHI;
SHIGERU AMANO;
HIROSHI SAKAGAMI

Publication type:

Article