Works by Sajjakulnukit, Peter

Results: 15

Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.100747

By:

Goswami, Moloy T.;
Weh, Eric;
Subramanya, Shubha;
Weh, Katherine M.;
Durumutla, Hima Bindu;
Hager, Heather;
Miller, Nicholas;
Chaudhury, Sraboni;
Andren, Anthony;
Sajjakulnukit, Peter;
Li Zhang;
Besirli, Cagri;
Lyssiotis, Costas A.;
Wubben, Thomas J.

Publication type:

Article

Multiomic characterization of pancreatic cancer-associated macrophage polarization reveals deregulated metabolic programs driven by the GM-CSF-PI3K pathway.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.73796

By:

Boyer, Seth;
Ho-Joon Lee;
Steele, Nina;
Li Zhang;
Sajjakulnukit, Peter;
Andren, Anthony;
Ward, Matthew H.;
Singh, Rima;
Basrur, Venkatesha;
Yaqing Zhang;
Nesvizhskii, Alexey I.;
di Magliano, Marina Pasca;
Halbrook, Christopher J.;
Lyssiotis, Costas A.

Publication type:

Article

Hyaluronic acid fuels pancreatic cancer cell growth.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.62645

By:

Kim, Peter K.;
Halbrook, Christopher J.;
Kerk, Samuel A.;
Radyk, Megan;
Wisner, Stephanie;
Kremer, Daniel M.;
Sajjakulnukit, Peter;
Andren, Anthony;
Hou, Sean W.;
Trivedi, Ayush;
Thurston, Galloway;
Anand, Abhinav;
Liang Yan;
Salamanca-Cardona, Lucia;
Welling, Samuel D.;
Li Zhang;
Pratt, Matthew R.;
Keshari, Kayvan R.;
Haoqiang Ying;
Lyssiotis, Costas A.

Publication type:

Article

GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24859-2

By:

Kremer, Daniel M.;
Nelson, Barbara S.;
Lin, Lin;
Yarosz, Emily L.;
Halbrook, Christopher J.;
Kerk, Samuel A.;
Sajjakulnukit, Peter;
Myers, Amy;
Thurston, Galloway;
Hou, Sean W.;
Carpenter, Eileen S.;
Andren, Anthony C.;
Nwosu, Zeribe C.;
Cusmano, Nicholas;
Wisner, Stephanie;
Mbah, Nneka E.;
Shan, Mengrou;
Das, Nupur K.;
Magnuson, Brian;
Little, Andrew C.

Publication type:

Article

Itaconate potentiates hepatic gluconeogenesis through NRF2 induction.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322946

By:

El-Derany, Marwa O.;
Ramakrishnan, Sadeesh K.;
Li, Yingjie;
Buscher, Kathryn;
Jarad, Christina A.;
Schaller, Megan L.;
Cantwell, Marc;
Vigil, Thomas M.;
Frieler, Ryan A.;
Sajjakulnukit, Peter;
Lyssiotis, Costas A.;
Mortensen, Richard M.;
Shah, Yatrik M.

Publication type:

Article

A large-scale analysis of targeted metabolomics data from heterogeneous biological samples provides insights into metabolite dynamics.

Published in:

Metabolomics, 2019, v. 15, n. 7, p. N.PAG, doi. 10.1007/s11306-019-1564-8

By:

Lee, Ho-Joon;
Kremer, Daniel M.;
Sajjakulnukit, Peter;
Zhang, Li;
Lyssiotis, Costas A.

Publication type:

Article

Purine metabolism regulates DNA repair and therapy resistance in glioblastoma.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17512-x

By:

Zhou, Weihua;
Yao, Yangyang;
Scott, Andrew J.;
Wilder-Romans, Kari;
Dresser, Joseph J.;
Werner, Christian K.;
Sun, Hanshi;
Pratt, Drew;
Sajjakulnukit, Peter;
Zhao, Shuang G.;
Davis, Mary;
Nelson, Barbara S.;
Halbrook, Christopher J.;
Zhang, Li;
Gatto, Francesco;
Umemura, Yoshie;
Walker, Angela K.;
Kachman, Maureen;
Sarkaria, Jann N.;
Xiong, Jianping

Publication type:

Article

HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.

Published in:

2021

By:

Singhal, Rashi;
Mitta, Sreedhar R.;
Das, Nupur K.;
Kerk, Samuel A.;
Sajjakulnukit, Peter;
Solanki, Sumeet;
Andren, Anthony;
Kumar, Roshan;
Olive, Kenneth P.;
Banerjee, Ruma;
Lyssiotis, Costas A.;
Shah, Yatrik M.

Publication type:

journal article

The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics.

Published in:

2021

By:

Giblin, William;
Bringman-Rodenbarger, Lauren;
Guo, Angela H.;
Kumar, Surinder;
Monovich, Alexander C.;
Mostafa, Ahmed M.;
Skinner, Mary E.;
Azar, Michelle;
Mady, Ahmed S. A.;
Chung, Carolina H.;
Kadambi, Namrata;
Melong, Keith-Allen;
Ho-Joon Lee;
Li Zhang;
Sajjakulnukit, Peter;
Trefely, Sophie;
Varner, Erika L.;
Iyer, Sowmya;
Min Wang;
Wilmott, James S.

Publication type:

journal article

Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52973-4

By:

Mbah, Nneka E.;
Myers, Amy L.;
Sajjakulnukit, Peter;
Chung, Chan;
Thompson, Joyce K.;
Hong, Hanna S.;
Giza, Heather;
Dang, Derek;
Nwosu, Zeribe C.;
Shan, Mengrou;
Sweha, Stefan R.;
Maydan, Daniella D.;
Chen, Brandon;
Zhang, Li;
Magnuson, Brian;
Zhu, Zirui;
Radyk, Megan;
Lavoie, Brooke;
Yadav, Viveka Nand;
Koo, Imhoi

Publication type:

Article

Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.73245

By:

Kerk, Samuel A.;
Lin Lin;
Myers, Amy L.;
Sutton, Damien J.;
Andren, Anthony;
Sajjakulnukit, Peter;
Li Zhang;
Yaqing Zhang;
Jiménez, Jennifer A.;
Nelson, Barbara S.;
Chen, Brandon;
Robinson, Anthony;
Thurston, Galloway;
Kemp, Samantha B.;
Steele, Nina G.;
Hoffman, Megan T.;
Hui-Ju Wen;
Long, Daniel;
Ackenhusen, Sarah E.;
Ramos, Johanna

Publication type:

Article

Purine salvage promotes treatment resistance in H3K27M-mutant diffuse midline glioma.

Published in:

Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00341-7

By:

Peterson, Erik R.;
Sajjakulnukit, Peter;
Scott, Andrew J.;
Heaslip, Caleb;
Andren, Anthony;
Wilder-Romans, Kari;
Zhou, Weihua;
Palavalasa, Sravya;
Korimerla, Navyateja;
Lin, Angelica;
O'Brien, Alexandra;
Kothari, Ayesha;
Zhao, Zitong;
Zhang, Li;
Morgan, Meredith A.;
Venneti, Sriram;
Koschmann, Carl;
Jabado, Nada;
Lyssiotis, Costas A.;
Castro, Maria G.

Publication type:

Article

Auditory metabolomics, an approach to identify acute molecular effects of noise trauma.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-45385-8

By:

Ji, Lingchao;
Lee, Ho-Joon;
Wan, Guoqiang;
Wang, Guo-Peng;
Zhang, Li;
Sajjakulnukit, Peter;
Schacht, Jochen;
Lyssiotis, Costas A.;
Corfas, Gabriel

Publication type:

Article

Deep annotation of untargeted LC-MS metabolomics data with Binner.

Published in:

Bioinformatics, 2020, v. 36, n. 6, p. 1801, doi. 10.1093/bioinformatics/btz798

By:

Kachman, Maureen;
Habra, Hani;
Duren, William;
Wigginton, Janis;
Sajjakulnukit, Peter;
Michailidis, George;
Burant, Charles;
Karnovsky, Alla

Publication type:

Article

OXPHOS promotes apoptotic resistance and cellular persistence in T<sub>H</sub>17 cells in the periphery and tumor microenvironment.

Published in:

Science Immunology, 2022, v. 7, n. 77, p. 1, doi. 10.1126/sciimmunol.abm8182

By:

Hong, Hanna S.;
Mbah, Nneka E.;
Shan, Mengrou;
Loesel, Kristen;
Lin, Lin;
Sajjakulnukit, Peter;
Correa, Luis O.;
Andren, Anthony;
Lin, Jason;
Hayashi, Atsushi;
Magnuson, Brian;
Chen, Judy;
Li, Zhaoheng;
Xie, Yuying;
Zhang, Li;
Goldstein, Daniel R.;
Carty, Shannon A.;
Lei, Yu Leo;
Opipari, Anthony W.;
Argüello, Rafael J.

Publication type:

Article