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Electronic adherence monitoring identifies severe preschool wheezers who are steroid responsive.
Published in:
Pediatric Pulmonology, 2020, v. 55, n. 9, p. 2254, doi. 10.1002/ppul.24943
By:
- Bingham, Yvonne;
- Sanghani, Nina;
- Cook, James;
- Hall, Pippa;
- Jamalzadeh, Angela;
- Moore‐Crouch, Rachael;
- Bush, Andrew;
- Fleming, Louise;
- Saglani, Sejal
Publication type:
Article
Lung clearance index and steroid response in pediatric severe asthma.
Published in:
Pediatric Pulmonology, 2020, v. 55, n. 4, p. 890, doi. 10.1002/ppul.24675
By:
- Irving, Samantha;
- Fleming, Louise;
- Ahmad, Fatima;
- Biggart, Elizabeth;
- Bingham, Yvvone;
- Cook, James;
- Hall, Pippa;
- Jamalzadeh, Angela;
- Nagakumar, Prasad;
- Bossley, Cara;
- Gupta, Atul;
- Macleod, Kenneth;
- Saglani, Sejal;
- Bush, Andrew
Publication type:
Article
Growth of the airway smooth muscle layer from late gestation to childhood is mediated initially by hypertrophy and subsequently hyperplasia.
Published in:
Respirology, 2022, v. 27, n. 7, p. 493, doi. 10.1111/resp.14240
By:
- Wang, Kimberley C. W.;
- Donovan, Graham M.;
- Saglani, Sejal;
- Mauad, Thais;
- James, Alan L.;
- Elliot, John G.;
- Noble, Peter B.
Publication type:
Article
Immunoregulation of asthma by type 2 cytokine therapies: Treatments for all ages?
Published in:
European Journal of Immunology, 2023, v. 53, n. 8, p. 1, doi. 10.1002/eji.202249919
By:
- Saglani, Sejal;
- Yates, Laura;
- Lloyd, Clare M.
Publication type:
Article
The role of 1α,25-dihydroxyvitamin D3 and cytokines in the promotion of distinct Foxp3+and IL-10+ CD4+ T cells.
Published in:
European Journal of Immunology, 2012, v. 42, n. 10, p. 2697, doi. 10.1002/eji.201242370
By:
- Urry, Zoë;
- Chambers, Emma S.;
- Xystrakis, Emmanuel;
- Dimeloe, Sarah;
- Richards, David F.;
- Gabryšová, Leona;
- Christensen, Jillian;
- Gupta, Atul;
- Saglani, Sejal;
- Bush, Andrew;
- O'Garra, Anne;
- Brown, Zarin;
- Hawrylowicz, Catherine M.
Publication type:
Article
Application of Metabolomics in Obesity-Related Childhood Asthma Subtyping: A Narrative Scoping Review.
Published in:
Metabolites (2218-1989), 2023, v. 13, n. 3, p. 328, doi. 10.3390/metabo13030328
By:
- Makrinioti, Heidi;
- Zhu, Zhaozhong;
- Camargo Jr., Carlos A.;
- Fainardi, Valentina;
- Hasegawa, Kohei;
- Bush, Andrew;
- Saglani, Sejal
Publication type:
Article
Microbial dysbiosis and childhood asthma development: Integrated role of the airway and gut microbiome, environmental exposures, and host metabolic and immune response.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1028209
By:
- Liu, Conglin;
- Makrinioti, Heidi;
- Saglani, Sejal;
- Bowman, Michael;
- Lih-Ling Lin;
- Camargo Jr., Carlos A.;
- Hasegawa, Kohei;
- Zhaozhong Zhu
Publication type:
Article
Lung microbiota promotes tolerance to allergens in neonates via PD-L1.
Published in:
Nature Medicine, 2014, v. 20, n. 6, p. 642, doi. 10.1038/nm.3568
By:
- Gollwitzer, Eva S;
- Saglani, Sejal;
- Trompette, Aurélien;
- Yadava, Koshika;
- Sherburn, Rebekah;
- McCoy, Kathy D;
- Nicod, Laurent P;
- Lloyd, Clare M;
- Marsland, Benjamin J
Publication type:
Article
Eosinophils in the Spotlight: Finding the link between obesity and asthma.
Published in:
Nature Medicine, 2013, v. 19, n. 8, p. 976, doi. 10.1038/nm.3296
By:
- Lloyd, Clare M;
- Saglani, Sejal
Publication type:
Article
Asthma and allergy: The emerging epithelium.
Published in:
Nature Medicine, 2010, v. 16, n. 3, p. 273, doi. 10.1038/nm0310-273
By:
- Lloyd, Clare M.;
- Saglani, Sejal
Publication type:
Article
The relationship between inflammation and remodeling in childhood asthma: A systematic review.
Published in:
Pediatric Pulmonology, 2018, v. 53, n. 6, p. 824, doi. 10.1002/ppul.23968
By:
- Castro-Rodriguez, Jose A.;
- Saglani, Sejal;
- Rodriguez-Martinez, Carlos E.;
- Oyarzun, Maria A.;
- Fleming, Louis;
- Bush, Andrew
Publication type:
Article
Infection and inflammation in induced sputum from preschool children with chronic airways diseases.
Published in:
Pediatric Pulmonology, 2016, v. 51, n. 8, p. 778, doi. 10.1002/ppul.23366
By:
- Jochmann, Anja;
- Artusio, Luca;
- Robson, Karen;
- Nagakumar, Prasad;
- Collins, Nicola;
- Fleming, Louise;
- Bush, Andrew;
- Saglani, Sejal
Publication type:
Article
An alternative to lung transplantation.
Published in:
Pediatric Pulmonology, 2003, v. 36, n. 4, p. 357, doi. 10.1002/ppul.10355
By:
- Gordon Cohen;
- Sejal Saglani;
- Robert Dinwiddie;
- Michael Webb;
- Adam Jaffé
Publication type:
Article
Cystic fibrosis and down's syndrome: Not always a poor prognosis.
Published in:
Pediatric Pulmonology, 2001, v. 31, n. 4, p. 321, doi. 10.1002/ppul.1049
By:
- Saglani, Sejal;
- Bush, Andrew
Publication type:
Article
Asthma Inception: Epidemiologic Risk Factors and Natural History Across the Life Course.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2024, v. 210, n. 6, p. 737, doi. 10.1164/rccm.202312-2249SO
By:
- Melén, Erik;
- Zar, Heather J.;
- Siroux, Valerie;
- Shaw, Dominic;
- Saglani, Sejal;
- Koppelman, Gerard H.;
- Hartert, Tina;
- Gern, James E.;
- Gaston, Benjamin;
- Bush, Andrew;
- Zein, Joe
Publication type:
Article
Asthma: Closing in on the Biology of a Complex Life-course Disease.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2023, v. 207, n. 4, p. 375, doi. 10.1164/rccm.202212-2302ED
By:
- Bush, Andrew;
- Holguin, Fernando;
- Porsbjerg, Celeste;
- Saglani, Sejal
Publication type:
Article
Remodeling Phenotypes Take Center Stage in the Prediction of Preschool Wheeze Attacks.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2023, v. 207, n. 4, p. 381, doi. 10.1164/rccm.202209-1833ED
By:
- Saglani, Sejal;
- Baraldo, Simonetta
Publication type:
Article
An Alarmin Role for P2Y13 Receptor during Viral-driven Asthma Exacerbations.
Published in:
2022
By:
- Byrne, Adam J.;
- Saglani, Sejal;
- Snelgrove, Robert J.
Publication type:
Editorial
Recurrent Severe Preschool Wheeze: From Prespecified Diagnostic Labels to Underlying Endotypes.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2021, v. 204, n. 5, p. 523, doi. 10.1164/rccm.202009-3696OC
By:
- Robinson, Polly F. M.;
- Fontanella, Sara;
- Ananth, Sachin;
- Alonso, Aldara Martin;
- Cook, James;
- Kaya-de Vries, Daphne;
- Silveira, Luisa Polo;
- Gregory, Lisa;
- Lloyd, Clare;
- Fleming, Louise;
- Bush, Andrew;
- Custovic, Adnan;
- Saglani, Sejal
Publication type:
Article
Update in Asthma 2019.
Published in:
2020
By:
- Saglani, Sejal;
- Wisnivesky, Juan P.;
- Charokopos, Antonios;
- Pascoe, Christopher D.;
- Halayko, Andrew J.;
- Custovic, Adnan
Publication type:
journal article
Childhood Asthma: Advances Using Machine Learning and Mechanistic Studies.
Published in:
2019
By:
- Saglani, Sejal;
- Custovic, Adnan
Publication type:
journal article
Asthma Attacks in Children: Does Blocking IgE Reduce Rhinovirus Infections?
Published in:
2017
By:
- Saglani, Sejal;
- Bush, Andrew
Publication type:
journal article
Prostacyclin as a Potential Novel Means to Manipulate Type 2 Innate Lymphoid Cell Function.
Published in:
2016
By:
- Saglani, Sejal;
- Lloyd, Clare M.
Publication type:
commentary
Onset of Structural Airway Changes in Preschool Wheezers. A Window and Target for Secondary Asthma Prevention?
Published in:
2015
By:
- Saglani, Sejal;
- Bush, Andrew
Publication type:
Editorial
Onset of Structural Airway Changes in Preschool Wheezers.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2015, v. 192, n. 2, p. 121, doi. 10.1164/rccm.201505-0989ed
By:
- Saglani, Sejal;
- Bush, Andrew
Publication type:
Article
Managing the pediatric patient with refractory asthma: a multidisciplinary approach.
Published in:
Journal of Asthma & Allergy, 2017, v. 10, p. 123, doi. 10.2147/JAA.S129159
By:
- Cook, James;
- Beresford, Fran;
- Fainardi, Valentina;
- Hall, Pippa;
- Housley, Georgie;
- Jamalzadeh, Angela;
- Nightingale, Michelle;
- Winch, David;
- Bush, Andrew;
- Fleming, Louise;
- Saglani, Sejal
Publication type:
Article
Structurally Unsound? Why Airways Become Asthmatic.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2018, v. 59, n. 4, p. 405, doi. 10.1165/rcmb.2018-0181ed
By:
- Bush, Andrew;
- Saglani, Sejal
Publication type:
Article
Pathophysiological Features of Asthma Develop in Parallel in House Dust Mite-Exposed Neonatal Mice.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2009, v. 41, n. 3, p. 281, doi. 10.1165/rcmb.2008-0396OC
By:
- Saglani, Sejal;
- Mathie, Sara A.;
- Gregory, Lisa G.;
- Bell, Matthew J.;
- Bush, Andrew;
- Lloyd, Clare M.
Publication type:
Article
Development of allergic immunity in early life.
Published in:
Immunological Reviews, 2017, v. 278, n. 1, p. 101, doi. 10.1111/imr.12562
By:
- Lloyd, Clare M.;
- Saglani, Sejal
Publication type:
Article
Comparative primary paediatric nasal epithelial cell culture differentiation and RSV-induced cytopathogenesis following culture in two commercial media.
Published in:
PLoS ONE, 2020, v. 15, n. 3, p. 1, doi. 10.1371/journal.pone.0228229
By:
- Broadbent, Lindsay;
- Manzoor, Sheerien;
- Zarcone, Maria C.;
- Barabas, Judit;
- Shields, Michael D.;
- Saglani, Sejal;
- Lloyd, Claire M.;
- Bush, Andrew;
- Custovic, Adnan;
- Ghazal, Peter;
- Gore, Mindy;
- Marsland, Ben;
- Roberts, Graham;
- Schwarze, Jurgen;
- Turner, Steve;
- Power, Ultan F.
Publication type:
Article
Primary care of children and young people with asthma during the COVID-19 era.
Published in:
2020
By:
- Creese, Hanna;
- Taylor-Robinson, David;
- Saglani, Sejal;
- Saxena, Sonia
Publication type:
Editorial
Adolescence: the last frontier.
Published in:
Jornal de Pediatria, 2012, v. 88, n. 5, p. 371, doi. 10.2223/JPED.2226
By:
- Bush, Andrew;
- Saglani, Sejal
Publication type:
Article
Inception of early-life allergen-induced airway hyperresponsiveness is reliant on IL-13+CD4+ T cells.
Published in:
Science Immunology, 2018, v. 3, n. 27, p. 1, doi. 10.1126/sciimmunol.aan4128
By:
- Saglani, Sejal;
- Gregory, Lisa G.;
- Manghera, Avneet K.;
- Branchett, William J.;
- Uwadiae, Faith;
- Entwistle, Lewis J.;
- Oliver, R. A.;
- Vasiliou, Jessica E.;
- Sherburn, Rebekah;
- Lui, Stephen;
- Puttur, F.;
- Vöhringer, David;
- Walker, Simone A.;
- Buckley, James;
- Grychtol, Ruth;
- Fainardi, Valentina;
- Denney, Laura;
- Byrne, Adam;
- von Mutius, Erika;
- Bush, Andrew
Publication type:
Article
Preventing progression of preschool wheezing to asthma: Opportunities for intervention.
Published in:
Pediatric Allergy & Immunology, 2024, v. 35, n. 6, p. 1, doi. 10.1111/pai.14180
By:
- Saglani, Sejal
Publication type:
Article
Changes in blood eosinophil levels in early childhood and asthma development: A case-control study.
Published in:
Pediatric Allergy & Immunology, 2022, v. 33, n. 2, p. 1, doi. 10.1111/pai.13734
By:
- Levina, Daria;
- Leontjeva, Marina;
- Abbasova, Nilgyun;
- Petrova, Yulia;
- Bitieva, Rita;
- Erdes, Svetlana I.;
- Aminova, Alfiya I.;
- Nurtazina, Asel;
- Blyuss, Boris;
- Pikuza, Maria;
- Avdeenko, Nina V.;
- Gadetskaya, Svetlana;
- Ivanova, Yulia V.;
- Saglani, Sejal;
- Bush, Andrew;
- Munblit, Daniel
Publication type:
Article
Blood eosinophils in managing preschool wheeze: Lessons learnt from a proof‐of‐concept trial.
Published in:
Pediatric Allergy & Immunology, 2022, v. 33, n. 1, p. 1, doi. 10.1111/pai.13697
By:
- Saglani, Sejal;
- Bingham, Yvonne;
- Balfour‐Lynn, Ian;
- Goldring, Stephen;
- Gupta, Atul;
- Banya, Winston;
- Moreiras, John;
- Fleming, Louise;
- Bush, Andrew;
- Rosenthal, Mark;
- Kalayci, Ömer
Publication type:
Article
Pediatric problematic severe asthma: Recent advances in management.
Published in:
Pediatric Allergy & Immunology, 2021, v. 32, n. 7, p. 1405, doi. 10.1111/pai.13543
By:
- Scotney, Elizabeth;
- Burchett, Saskia;
- Goddard, Thomas;
- Saglani, Sejal;
- Kalaycı, Ömer
Publication type:
Article
Airway Inflammation and Remodelling in Childhood Asthma.
Published in:
Arerugi: Japanese Journal of Allergology, 2021, v. 70, n. 6/7, p. 568
By:
- Saglani, Sejal
Publication type:
Article
Glucocorticosteroids Are Potential Confounders in Studies of Vitamin D and Asthma.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2012, v. 185, n. 11, p. 1245, doi. 10.1164/ajrccm.185.11.1245a
By:
- GUPTA, ATUL;
- HAWRYLOWICZ, CATHERINE;
- RICHARDS, DAVID;
- BUSH, ANDREW;
- SAGLANI, SEJAL
Publication type:
Article
Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma.
Published in:
2011
By:
- Gupta A;
- Sjoukes A;
- Richards D;
- Banya W;
- Hawrylowicz C;
- Bush A;
- Saglani S;
- Gupta, Atul;
- Sjoukes, Alies;
- Richards, David;
- Banya, Winston;
- Hawrylowicz, Catherine;
- Bush, Andrew;
- Saglani, Sejal
Publication type:
journal article
Relationship between Serum Vitamin D, Disease Severity, and Airway Remodeling in Children with Asthma.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2011, v. 184, n. 12, p. 1342, doi. 10.1164/rccm.201107-1239oc
By:
- Gupta, Atul;
- Sioukes, Alies;
- Richards, David;
- Banya, Winston;
- Hawrylowicz, Catherine;
- Bush, Andrew;
- Saglani, Sejal
Publication type:
Article
Airway Remodeling and Inflammation in Symptomatic Infants with Reversible Airflow Obstruction.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2005, v. 171, n. 7, p. 722, doi. 10.1164/rccm.200410-1404OC
By:
- Saglani, Sejal;
- Malmström, Kristiina;
- Pelkonen, Anna S.;
- Malmberg, L. Pekka;
- Lindahl, Harry;
- Kajosaari, Merja;
- Turpeinen, Markku;
- Rogers, Andrew V.;
- Payne, Donald N.;
- Bush, Andrew;
- Haahtela, Tari;
- Mäkelä, Mika J.;
- Jeffery, Peter K.
Publication type:
Article
Severe asthma in children.
Published in:
Respirology, 2017, v. 22, n. 5, p. 886, doi. 10.1111/resp.13085
By:
- Bush, Andrew;
- Fleming, Louise;
- Saglani, Sejal
Publication type:
Article
Role of epithelial barrier function in inducing type 2 immunity following early‐life viral infection.
Published in:
Clinical & Experimental Allergy, 2024, v. 54, n. 2, p. 109, doi. 10.1111/cea.14425
By:
- Tian, Kunyuan;
- Dangarh, Prakrati;
- Zhang, Haina;
- Hines, Christian L.;
- Bush, Andrew;
- Pybus, Hannah J.;
- Harker, James A.;
- Lloyd, Clare M.;
- Tanaka, Reiko J.;
- Saglani, Sejal
Publication type:
Article
Impaired airway epithelial cell wound‐healing capacity is associated with airway remodelling following RSV infection in severe preschool wheeze.
Published in:
Allergy, 2020, v. 75, n. 12, p. 3195, doi. 10.1111/all.14466
By:
- Andersson, Cecilia K.;
- Iwasaki, Jua;
- Cook, James;
- Robinson, Polly;
- Nagakumar, Prasad;
- Mogren, Sofia;
- Fleming, Louise;
- Bush, Andrew;
- Saglani, Sejal;
- Lloyd, Clare M.
Publication type:
Article
Preschool wheeze: Challenges and research prospects reply to: Dr Jartti and Colleagues; in response to our manuscript entitled: Medical algorithm: Diagnosis and treatment of preschool asthma.
Published in:
Allergy, 2020, v. 75, n. 10, p. 2718, doi. 10.1111/all.14291
By:
- Bush, Andrew;
- Saglani, Sejal
Publication type:
Article
Medical algorithm: Diagnosis and treatment of preschool asthma.
Published in:
Allergy, 2020, v. 75, n. 10, p. 2711, doi. 10.1111/all.14172
By:
- Bush, Andrew;
- Saglani, Sejal
Publication type:
Article
Enhanced frequency and function of follicular T cells in the tonsils of house dust mite‐sensitized children.
Published in:
Allergy, 2020, v. 75, n. 5, p. 1240, doi. 10.1111/all.14150
By:
- Foster, William S.;
- Grime, Christopher J.;
- Tan, Hui‐Leng;
- Williams, Geoffrey S.;
- Robinson, Matthew J.;
- Carlesso, Gianluca;
- Saglani, Sejal;
- Lloyd, Clare M.;
- Harker, James A.
Publication type:
Article
Difficult-to-Treat Asthma in Childhood.
Published in:
Pediatric Drugs, 2013, v. 15, n. 3, p. 171, doi. 10.1007/s40272-013-0025-5
By:
- Adams, Alexandra;
- Saglani, Sejal
Publication type:
Article
Diagnosis and Management of Problematic Severe Asthma.
Published in:
Acta Medica Academica, 2020, v. 49, n. 2, p. 117, doi. 10.5644/ama2006-124.291
By:
- Scotney, Elizabeth;
- Saglani, Sejal
Publication type:
Article

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