Works by Sabroe, Ian

Results: 46

Maximal Exercise Testing Using the Incremental Shuttle Walking Test Can Be Used to Risk-Stratify Patients with Pulmonary Arterial Hypertension.

Published in:

2021

By:

Lewis, Robert A.;
Billings, Catherine G.;
Hurdman, Judith A.;
Smith, Ian A.;
Austin, Matthew;
Armstrong, Iain J.;
Middleton, Jennifer;
Rothman, Alexander M. K.;
Harrington, John;
Hamilton, Neil;
Hameed, Abdul G.;
Thompson, A. A. Roger;
Charalampopoulos, Athanasios;
Elliot, Charlie A.;
Lawrie, Allan;
Sabroe, Ian;
Wild, Jim M.;
Swift, Andrew J.;
Condliffe, Robin;
Kiely, David G.

Publication type:

journal article

The carboxyl terminus of the chemokine receptor CCR3 contains distinct domains which regulate chemotactic signaling and receptor down-regulation in a ligand-dependent manner.

Published in:

European Journal of Immunology, 2005, v. 35, n. 4, p. 1301, doi. 10.1002/eji.200425171

By:

Sabroe, Ian;
Jorritsma, Annelies;
Stubbs, Victoria E. L.;
Xanthou, Georgina;
Jopling, Louise A.;
Ponath, Paul D.;
Williams, Timothy J.;
Murphy, Philip M.;
Pease, James E.

Publication type:

Article

CCR4 in human allergen-induced late responses in the skin and lung.

Published in:

European Journal of Immunology, 2002, v. 32, n. 7, p. 1933, doi. 10.1002/1521-4141(200207)32:7<1933::AID-IMMU1933>3.0.CO;2-R

By:

Nouri-Aria, Kayhan T.;
Wilson, Duncan;
Francis, James N.;
Jopling, Louise A.;
Jacobson, Mikila R.;
Hodge, Martin R.;
Andrew, David P.;
Till, Stephen J.;
Varga, Eva-Maria;
Williams, Timothy J.;
Pease, James E.;
Lloyd, Clare M.;
Sabroe, Ian;
Durham, Stephen R.

Publication type:

Article

Examining the impact of pulmonary hypertension on nonprofessional caregivers: A mixed‐methods systematic review.

Published in:

Pulmonary Circulation, 2022, v. 12, n. 2, p. 1, doi. 10.1002/pul2.12077

By:

Rawlings, Gregg H.;
Beail, Nigel;
Condliffe, Robin;
Kiely, David G.;
Thompson, Andrew R.;
Sabroe, Ian;
Armstrong, Iain

Publication type:

Article

Elective lower limb orthopedic arthroplasty surgery in patients with pulmonary hypertension.

Published in:

Pulmonary Circulation, 2022, v. 12, n. 1, p. 1, doi. 10.1002/pul2.12019

By:

Wardle, Mikaela;
Nair, Amanda;
Saunders, Sarah;
Armstrong, Iain;
Charalampopoulos, Athanasios;
Elliot, Charlie;
Hameed, Abdul;
Hamilton, Neil;
Harrington, John;
Keen, Carol;
Lewis, Robert;
Sabroe, Ian;
Thompson, A. A. Roger;
Kerry, Robert M.;
Condliffe, Robin;
Kiely, David G.

Publication type:

Article

The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE Registry.

Published in:

Pulmonary Circulation, 2019, v. 9, n. 2, p. N.PAG, doi. 10.1177/2045894019848649

By:

Billings, Catherine G.;
Lewis, Robert;
Hurdman, Judith A.;
Condliffe, Robin;
Elliot, Charlie A.;
Thompson, A.A. Roger;
Smith, Ian A.;
Austin, Matthew;
Armstrong, Iain J.;
Hamilton, Neil;
Charalampopoulos, Athanasios;
Sabroe, Ian;
Swift, Andrew J.;
Rothman, Alexander M.;
Wild, Jim M.;
Lawrie, Allan;
Waterhouse, Judith C.;
Kiely, David G.

Publication type:

Article

Cooperative molecular and cellular networks regulate Toll-like receptor-dependent inflammatory responses.

Published in:

FASEB Journal, 2006, v. 20, n. 12, p. 2153, doi. 10.1096/fj.06-5910fje

By:

Morris, Gavin E.;
Parker, Lisa C.;
Ward, Jon R.;
Jones, Elizabeth C.;
Whyte, Moira K. B.;
Brightling, Christopher E.;
Bradding, Peter;
Dower, Steven K.;
Sabroe, Ian

Publication type:

Article

Effect of Hypoglycemia on Inflammatory Responses and the Response to Low-Dose Endotoxemia in Humans.

Published in:

2018

By:

Iqbal, Ahmed;
Prince, Lynne R;
Novodvorsky, Peter;
Bernjak, Alan;
Thomas, Mark R;
Birch, Lewis;
Lambert, Danielle;
Kay, Linda J;
Wright, Fiona J;
Macdonald, Ian A;
Jacques, Richard M;
Storey, Robert F;
McCrimmon, Rory J;
Francis, Sheila;
Heller, Simon R;
Sabroe, Ian

Publication type:

journal article

Identification of Cardiac Magnetic Resonance Imaging Thresholds for Risk Stratification in Pulmonary Arterial Hypertension.

Published in:

2020

By:

Lewis, Robert A.;
Johns, Christopher S.;
Cogliano, Marcella;
Capener, David;
Tubman, Euan;
Elliot, Charlie A.;
Charalampopoulos, Athanasios;
Sabroe, Ian;
Thompson, A. A. Roger;
Billings, Catherine G.;
Hamilton, Neil;
Baster, Kathleen;
Laud, Peter J.;
Hickey, Peter M.;
Middleton, Jennifer;
Armstrong, Iain J.;
Hurdman, Judith A.;
Lawrie, Allan;
Rothman, Alexander M. K.;
Wild, Jim M.

Publication type:

journal article

Human Rhinovirus Inhibits Macrophage Phagocytosis of Bacteria in Chronic Obstructive Pulmonary Disease. More Than a Common Cold.

Published in:

2019

By:

Sabroe, Ian;
Ho, Antonia;
Dockrell, David H

Publication type:

journal article

Toll-like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension.

Published in:

2019

By:

Farkas, Daniela;
Thompson, A A Roger;
Bhagwani, Aneel R;
Hultman, Schuyler;
Ji, Hyun;
Kotha, Naveen;
Farr, Grant;
Arnold, Nadine D;
Braithwaite, Adam;
Casbolt, Helen;
Cole, Jennifer E;
Sabroe, Ian;
Monaco, Claudia;
Cool, Carlyne D;
Goncharova, Elena A;
Lawrie, Allan;
Farkas, Laszlo

Publication type:

journal article

The effect of inhaled interferon-beta on worsening of asthma symptoms caused by viral infections: a randomised trial.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2014, v. 190, n. 2, p. E1, doi. 10.1164/rccm.201312-2235oc

By:

Djukanović, Ratko;
Davies, Donna E.;
Holgate, Stephen T.;
Harrison, Tim;
Brightling, Christopher;
Johnston, Sebastian;
Niven, Robert;
Reddel, Helen;
de Looze, Ferdinandus;
Wark, Peter;
Bardin, Phillip;
Thomson, Neil C.;
Heaney, Liam;
McGarvey, Lorcan;
Sabroe, Ian;
Higgins, Bernard;
Arya, Mark;
Strang, Christopher;
Rahman, Najib;
Oyesile, Babatunde

Publication type:

Article

Airway Epithelial Cells Generate Pro-inflammatory Tenascin-C and Small Extracellular Vesicles in Response to TLR3 Stimuli and Rhinovirus Infection.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01987

By:

Mills, Jake T.;
Schwenzer, Anja;
Marsh, Elizabeth K.;
Edwards, Michael R.;
Sabroe, Ian;
Midwood, Kim S.;
Parker, Lisa C.

Publication type:

Article

Pellino-1 Regulates Immune Responses to Haemophilus influenzae in Models of Inflammatory Lung Disease.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01721

By:

Hughes, Bethany M.;
Burton, Charlotte S.;
Reese, Abigail;
Jabeen, Maisha F.;
Wright, Carl;
Willis, Jessica;
Khoshaein, Nika;
Marsh, Elizabeth K.;
Peachell, Peter;
Sun, Shao C.;
Dockrell, David H.;
Marriott, Helen M.;
Sabroe, Ian;
Condliffe, Alison M.;
Prince, Lynne R.

Publication type:

Article

Ex Vivo-Expanded Bone Marrow CD34+ Derived Neutrophils Have Limited Bactericidal Ability.

Published in:

Stem Cells, 2008, v. 26, n. 10, p. 2552, doi. 10.1634/stemcells.2008-0328

By:

Dick, Emily Patricia;
Prince, Lynne Rebecca;
Sabroe, Ian

Publication type:

Article

Targeting the Networks that Underpin Contiguous Immunity in Asthma and Chronic Obstructive Pulmonary Disease.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2007, v. 175, n. 4, p. 306, doi. 10.1164/rccm.200606-777pp

By:

Sabroe, Ian;
Parker, Lisa C.;
Dockrell, David H.;
Davies, Donna E.;
Dower, Steven K.;
Whyte, Moira K. B.

Publication type:

Article

Agonists of Toll-like Receptors 2 and 4 Activate Airway Smooth Muscle via Mononuclear Leukocytes.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2005, v. 171, n. 8, p. 814, doi. 10.1164/rccm.200403-406OC

By:

Morris, Gavin E.;
Whyte, Moira K. B.;
Martin, Gillian F.;
Jose, Peter J.;
Dower, Steven K.;
Sabroe, Ian

Publication type:

Article

Invited review: Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease.

Published in:

Innate Immunity, 2006, v. 12, n. 3, p. 133, doi. 10.1177/09680519060120030201

By:

Medvedev, Andrei E.;
Sabroe, Ian;
Hasday, Jeffrey D.;
Vogel, Stefanie N.

Publication type:

Article

The Role of Toll-Like Receptors in the Regulation of Neutrophil Migration, Activation, and Apoptosis.

Published in:

Clinical Infectious Diseases, 2005, v. 41, p. S421, doi. 10.1086/431992

By:

Sabroe, Ian;
Dower, Steven K.;
Whyte, Moira K. B.

Publication type:

Article

Incapacitating the immune system in cystic fibrosis.

Published in:

Nature Medicine, 2007, v. 13, n. 12, p. 1417, doi. 10.1038/nm1207-1417

By:

Sabroe, Ian;
Whyte, Moira K. B.

Publication type:

Article

Effect of Hypoglycemia on Inflammatory Responses and the Response to Low-Dose Endotoxemia in Humans.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2019, v. 104, n. 4, p. 1187, doi. 10.1210/jc.2018-01168

By:

Iqbal, Ahmed;
Prince, Lynne R.;
Novodvorsky, Peter;
Bernjak, Alan;
Thomas, Mark R.;
Birch, Lewis;
Lambert, Danielle;
Kay, Linda J.;
Wright, Fiona J.;
Macdonald, Ian A.;
Jacques, Richard M.;
Storey, Robert F.;
McCrimmon, Rory J.;
Francis, Sheila;
Heller, Simon R.;
Sabroe, Ian

Publication type:

Article

Management of acute pulmonary embolism.

Published in:

British Journal of Hospital Medicine (17508460), 2015, v. 76, n. 10, p. C150, doi. 10.12968/hmed.2015.76.10.C150

By:

Quadery, Rehan;
Elliot, Charlie A.;
Hurdman, Judith;
Kiely, David G.;
Maclean, Rhona M.;
Sabroe, Ian;
van Veen, Joost J.;
Condliffe, Robin

Publication type:

Article

Diagnostic accuracy of CT pulmonary angiography in suspected pulmonary hypertension.

Published in:

2020

By:

Swift, Andrew J.;
Dwivedi, Krit;
Johns, Chris;
Garg, Pankaj;
Chin, Matthew;
Currie, Ben J;
Rothman, Alex MK;
Capener, Dave;
Shahin, Yousef;
Elliot, Charlie A;
Charalampopolous, Thanos;
Sabroe, Ian;
Rajaram, Smitha;
Hill, Catherine;
Wild, Jim M.;
Condliffe, Robin;
Kiely, David G.

Publication type:

journal article

The care of dying people in 16th- and 17th-century England.

Published in:

Death Studies, 2020, v. 44, n. 5, p. 270, doi. 10.1080/07481187.2018.1541941

By:

Germain, Lewis;
Sabroe, Ian

Publication type:

Article

A central role for monocytes in Toll-like receptor-mediated activation of the vasculature.

Published in:

Immunology, 2009, v. 128, n. 1, p. 58, doi. 10.1111/j.1365-2567.2009.03071.x

By:

Ward, Jon R.;
Francis, Sheila E.;
Marsden, Luke;
Suddason, Tesha;
Lord, Graham M.;
Dower, Steven K.;
Crossman, David C.;
Sabroe, Ian

Publication type:

Article

Pathways regulating lipopolysaccharide-induced neutrophil survival revealed by lentiviral transduction of primary human neutrophils.

Published in:

Immunology, 2009, v. 127, n. 2, p. 249, doi. 10.1111/j.1365-2567.2008.02949.x

By:

Dick, Emily P.;
Prince, Lynne R.;
Prestwich, Elizabeth C.;
Renshaw, Stephen A.;
Whyte, Moira K. B.;
Sabroe, Ian

Publication type:

Article

Differential and cell-type specific regulation of responses to Toll-like receptor agonists by ISO-1.

Published in:

Immunology, 2008, v. 125, n. 1, p. 101, doi. 10.1111/j.1365-2567.2008.02825.x

By:

West, Peter W.;
Parker, Lisa C.;
Ward, Jon R.;
Sabroe, Ian

Publication type:

Article

Regulation of human neutrophil chemokine receptor expression and function by activation of Toll-like receptors 2 and 4.

Published in:

Immunology, 2005, v. 115, n. 1, p. 90, doi. 10.1111/j.1365-2567.2005.02133.x

By:

Sabroe, Ian;
Jones, Elizabeth C.;
Whyte, Moira K. B.;
Dower, Steven K.

Publication type:

Article

Circulating MicroRNA Levels Indicate Platelet and Leukocyte Activation in Endotoxemia Despite Platelet P2Y12 Inhibition.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 8, p. 2897, doi. 10.3390/ijms21082897

By:

Braza-Boïls, Aitana;
Barwari, Temo;
Gutmann, Clemens;
Thomas, Mark R.;
Judge, Heather M.;
Joshi, Abhishek;
Pechlaner, Raimund;
Shankar-Hari, Manu;
Ajjan, Ramzi A.;
Sabroe, Ian;
Storey, Robert F.;
Mayr, Manuel

Publication type:

Article

A social-technological epistemology of clinical decision-making as mediated by imaging.

Published in:

Journal of Evaluation in Clinical Practice, 2017, v. 23, n. 5, p. 949, doi. 10.1111/jep.12637

By:

Baalen, Sophie;
Carusi, Annamaria;
Sabroe, Ian;
Kiely, David G.

Publication type:

Article

UK consensus statement on the diagnosis of inducible laryngeal obstruction in light of the COVID‐19 pandemic.

Published in:

Clinical & Experimental Allergy, 2020, v. 50, n. 12, p. 1287, doi. 10.1111/cea.13745

By:

Haines, Jemma;
Esposito, Karen;
Slinger, Claire;
Pargeter, Nicola;
Murphy, Jennifer;
Selby, Julia;
Prior, Kathryn;
Mansur, Adel;
Vyas, Aashish;
Stanton, Andrew E.;
Sabroe, Ian;
Hull, James H.;
Fowler, Stephen J.

Publication type:

Article

Phosphoinositide-3 Kinase Inhibition Modulates Responses to Rhinovirus by Mechanisms that Are Predominantly Independent of Autophagy.

Published in:

PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0116055

By:

Ismail, Saila;
Stokes, Clare A.;
Prestwich, Elizabeth C.;
Roberts, Rebecca L.;
Juss, Jatinder K.;
Sabroe, Ian;
Parker, Lisa C.

Publication type:

Article

Macrophage Phenotype Is Associated with Disease Severity in Preterm Infants with Chronic Lung Disease.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0103059

By:

Prince, Lynne R.;
Maxwell, Nicola C.;
Gill, Sharonjit K.;
Dockrell, David H.;
Sabroe, Ian;
McGreal, Eamon P.;
Kotecha, Sailesh;
Whyte, Moira K.

Publication type:

Article

The Role of Interleukin-1 and Interleukin-18 in Pro-Inflammatory and Anti-Viral Responses to Rhinovirus in Primary Bronchial Epithelial Cells

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063365

By:

Piper, Siân C.;
Ferguson, John;
Kay, Linda;
Parker, Lisa C.;
Sabroe, Ian;
Sleeman, Matthew A.;
Briend, Emmanuel;
Finch, Donna K.

Publication type:

Article

Diesel Exhaust Particle Exposure In Vitro Alters Monocyte Differentiation and Function.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051107

By:

Chaudhuri, Nazia;
Jary, Hannah;
Lea, Simon;
Khan, Naimat;
Piddock, Katie C.;
Dockrell, David H.;
Donaldson, Ken;
Duffin, Rodger;
Singh, Dave;
Parker, Lisa C.;
Sabroe, Ian

Publication type:

Article

Staphylococcus aureus Induces Eosinophil Cell Death Mediated by α-hemolysin.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031506

By:

Prince, Lynne R.;
Graham, Kirstie J.;
Connolly, John;
Anwar, Sadia;
Ridley, Robert;
Sabroe, Ian;
Foster, Simon J.;
Whyte, Moira K. B.

Publication type:

Article

Effective Caspase Inhibition Blocks Neutrophil Apoptosis and Reveals Mcl-1 as Both a Regulator and a Target of Neutrophil Caspase Activation.

Published in:

PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0015768

By:

Wardle, David J.;
Burgon, Joseph;
Sabroe, Ian;
Bingle, Colin D.;
Whyte, Moira K. B.;
Renshaw, Stephen A.

Publication type:

Article

Ambrisentan therapy in pulmonary hypertension: clinical use and tolerability in a referral centre.

Published in:

Therapeutic Advances in Respiratory Disease, 2014, v. 8, n. 3, p. 71, doi. 10.1177/1753465814532304

By:

Condliffe, Robin;
Elliot, Charlie A.;
Hurdman, Judith;
Sabroe, Ian;
Billings, Catherine;
Kiely, David G.;
Hamilton, Neil

Publication type:

Article

Lung MRI with hyperpolarised gases: current & future clinical perspectives.

Published in:

British Journal of Radiology, 2022, v. 95, n. 1132, p. 1, doi. 10.1259/bjr.20210207

By:

Stewart, Neil J;
Smith, Laurie J;
Chan, Ho-Fung;
Eaden, James A;
Rajaram, Smitha;
Swift, Andrew J;
Weatherley, Nicholas D;
Biancardi, Alberto;
Collier, Guilhem J;
Hughes, David;
Klafkowski, Gill;
Johns, Christopher S;
West, Noreen;
Ugonna, Kelechi;
Bianchi, Stephen M;
Lawson, Rod;
Sabroe, Ian;
Marshall, Helen;
Wild, Jim M

Publication type:

Article

Identifying and hurdling obstacles to translational research.

Published in:

2007

By:

Sabroe, Ian;
Dockrell, David H.;
Vogel, Stefanie N.;
Renshaw, Stephen A.;
Whyte, Moira K. B.;
Dower, Steven K.

Publication type:

journal article

9α,11β-PGF2 and its stereoisomer PGF2α are novel agonists of the chemoattractant receptor, CRTH2

Published in:

FEBS Letters, 2006, v. 580, n. 2, p. 373, doi. 10.1016/j.febslet.2005.11.052

By:

Sandig, Hilary;
Andrew, David;
Barnes, Ashley A.;
Sabroe, Ian;
Pease, James

Publication type:

Article

Partial anomalous pulmonary venous drainage in patients presenting with suspected pulmonary hypertension: A series of 90 patients from the ASPIRE registry.

Published in:

Respirology, 2020, v. 25, n. 10, p. 1066, doi. 10.1111/resp.13815

By:

Lewis, Robert A.;
Billings, Catherine G.;
Bolger, Aidan;
Bowater, Sarah;
Charalampopoulos, Athanasios;
Clift, Paul;
Elliot, Charlie A.;
English, Kate;
Hamilton, Neil;
Hill, Catherine;
Hurdman, Judith;
Jenkins, Petra J.;
Johns, Christopher;
MacDonald, Simon;
Oliver, James;
Papaioannou, Vasilios;
Rajaram, Smitha;
Sabroe, Ian;
Swift, Andy J.;
Thompson, A.A. Roger

Publication type:

Article

Long-term outcomes of domiciliary intravenous iloprost in idiopathic and connective tissue disease-associated pulmonary arterial hypertension.

Published in:

Respirology, 2017, v. 22, n. 2, p. 372, doi. 10.1111/resp.12899

By:

Ramjug, Sheila;
Hussain, Nehal;
Hurdman, Judith;
Elliot, Charlie A.;
Sabroe, Ian;
Armstrong, Iain J.;
Billings, Catherine;
Hamilton, Neil;
Kiely, David G.;
Condliffe, Robin

Publication type:

Article

A Bittersweet Response to Infection in Diabetes; Targeting Neutrophils to Modify Inflammation and Improve Host Immunity.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.678771

By:

Dowey, Rebecca;
Iqbal, Ahmed;
Heller, Simon R.;
Sabroe, Ian;
Prince, Lynne R.

Publication type:

Article

DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator.

Published in:

Journal of Leukocyte Biology, 2018, v. 104, n. 1, p. 159, doi. 10.1002/JLB.3MA1017-404R

By:

Peinhaupt, Miriam;
Roula, David;
Theiler, Anna;
Sedej, Miriam;
Schicho, Rudolf;
Marsche, Gunther;
Sturm, Eva M.;
Sabroe, Ian;
Rothenberg, Marc E.;
Heinemann, Akos

Publication type:

Article

Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice.

Published in:

2011

By:

Walmsley, Sarah R.;
Chilvers, Edwin R.;
Thompson, Alfred A.;
Vaughan, Kathryn;
Marriott, Helen M.;
Parker, Lisa C.;
Shaw, Gary;
Parmar, Selina;
Schneider, Martin;
Sabroe, Ian;
Dockrell, David H.;
Milo, Marta;
Taylor, Cormac T.;
Johnson, Randall S.;
Pugh, Christopher W.;
Ratcliffe, Peter J.;
Maxwell, Patrick H.;
Carmeliet, Peter;
Whyte, Moira K. B.

Publication type:

journal article